UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549

SCHEDULE 13G

UNDER THE SECURITIES EXCHANGE ACT OF 1934

(Amendment No. 2)

Avigen, Inc.

___________________________________________

Name of Issuer

Common Stock, par value $0.001

___________________________________________

(Title of Class of Securities)

053690103

___________________________________________

(CUSIP Number)

December 18, 2009

_____________________________________________________________________

(Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

[ X ] Rule 13d-1(b)

[ _ ] Rule 13d-1(c)

[ _ ] Rule 13d-1(d)

The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the notes).


1	NAMES OF REPORTING PERSONS:

	Southpaw Asset Management LP

2	CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP			(a)	[__]
				(b)	[__]

3	SEC USE ONLY


4	CITIZENSHIP OR PLACE OF ORGANIZATION:

	Delaware


NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH		5	SOLE VOTING POWER	0

		6	SHARED VOTING POWER	0

		7	SOLE DISPOSITIVE POWER	0

		8	SHARED DISPOSITIVE POWER	0


9	AGGREGATE AMOUNT BENEFICALLY OWNED BY EACH REPORTING PERSON:

	0


10	CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES:				[__]


11	PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

	0.0%


12	TYPE OF REPORTING PERSON:

	PN


1	NAMES OF REPORTING PERSONS:

	Southpaw Holdings LLC

2	CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP			(a)	[__]
				(b)	[__]

3	SEC USE ONLY


4	CITIZENSHIP OR PLACE OF ORGANIZATION:

	Delaware


NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH		5	SOLE VOTING POWER	0

		6	SHARED VOTING POWER	0

		7	SOLE DISPOSITIVE POWER	0

		8	SHARED DISPOSITIVE POWER	0


9	AGGREGATE AMOUNT BENEFICALLY OWNED BY EACH REPORTING PERSON:

	0


10	CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES:				[__]


11	PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

	0.0%


12	TYPE OF REPORTING PERSON:

	OO


1	NAMES OF REPORTING PERSONS:

	Southpaw Credit Opportunity Master Fund LP

2	CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP			(a)	[__]
				(b)	[__]

3	SEC USE ONLY


4	CITIZENSHIP OR PLACE OF ORGANIZATION:

	Cayman Islands


NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH		5	SOLE VOTING POWER	0

		6	SHARED VOTING POWER	0

		7	SOLE DISPOSITIVE POWER	0

		8	SHARED DISPOSITIVE POWER	0


9	AGGREGATE AMOUNT BENEFICALLY OWNED BY EACH REPORTING PERSON:

	0


10	CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES:				[__]


11	PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

	0.0%


12	TYPE OF REPORTING PERSON:

	PN


1	NAMES OF REPORTING PERSONS:

	Kevin Wyman

2	CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP			(a)	[__]
				(b)	[__]

3	SEC USE ONLY


4	CITIZENSHIP OR PLACE OF ORGANIZATION:

	United States


NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH		5	SOLE VOTING POWER	0

		6	SHARED VOTING POWER	0

		7	SOLE DISPOSITIVE POWER	0

		8	SHARED DISPOSITIVE POWER	0


9	AGGREGATE AMOUNT BENEFICALLY OWNED BY EACH REPORTING PERSON:

	0


10	CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES:				[__]


11	PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

	0.0%


12	TYPE OF REPORTING PERSON:

	IN


1	NAMES OF REPORTING PERSONS:

	Howard Golden

2	CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP			(a)	[__]
				(b)	[__]

3	SEC USE ONLY


4	CITIZENSHIP OR PLACE OF ORGANIZATION:

	United States


NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH		5	SOLE VOTING POWER	0

		6	SHARED VOTING POWER	0

		7	SOLE DISPOSITIVE POWER	0

		8	SHARED DISPOSITIVE POWER	0


9	AGGREGATE AMOUNT BENEFICALLY OWNED BY EACH REPORTING PERSON:

	0


10	CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES:				[__]


11	PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

	0.0%


12	TYPE OF REPORTING PERSON:

	IN

ITEM 1(a)	NAME OF ISSUER:

	Avigen, Inc. (the “Issuer”)

ITEM 1(b)	ADDRESS OF ISSUER’S PRINICIPAL EXECUTIVE OFFICES:

	1301 Harbor Bay Parkway Alameda, California 94502

ITEM 2(a)	NAME OF PERSON FILING:

	This statement is filed on behalf of the following persons (collectively, the “Reporting Persons”):

	(i) Southpaw Asset Management LP

	(ii) Southpaw Credit Opportunity Master Fund LP

	(iii) Southpaw Holdings LLC

	(iv) Kevin Wyman

	(v) Howard Golden

	As of December 18, 2009, none of the Reporting Persons beneficially owns any shares of par value $0.001 per share common stock of the Issuer (“Common Stock”) nor has the power to vote or dispose of any shares of Common Stock.

ITEM 2(b)	ADDRESS OF PRINCIPAL BUSINESS OFFICE OR, IF NONE, RESIDENCE:

	Four Greenwich Office Park Greenwich, CT 06831

ITEM 2(c)	CITIZENSHIP:

	(i) Southpaw Asset Management LP is a limited partnership organized under the laws of Delaware.

	(ii) Southpaw Credit Opportunity Master Fund LP is a limited partnership organized under the laws of the Cayman Islands.

	(iii) Southpaw Holdings LLC is a limited liability company organized under the laws of Delaware.

	(iv) Kevin Wyman is an individual having citizenship in the United States.

	(v) Howard Golden is an individual having citizenship in the United States.


ITEM 2(d)	TITLE OF CLASS OF SECURITIES: Common Stock


ITEM 2(e)	CUSIP NUMBER: 053690103


ITEM 3	IF THIS STATEMENT IS FILED PURSUANT TO §§ 240.13d-1(b) OR 240.13d-2(b) OR (c), CHECK WHETHER THE FILING PERSON IS:


	(a) o Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o).
	(b) o Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c).
	(c) o Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c).
	(d) o Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8).
	(e) x An investment advisor in accordance with §240.13d-1(b)(1)(ii)(E).
	(f) o An employee benefit plan or endowment fund in accordance with §240.13d-1(b)(1)(ii)(F).
	(g) o A parent holding company or control person in accordance with §240.13d-1(b)(1)(ii)(G).
	(h) o A savings association as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813).
	(i) o A church plan that is excluded from the definition of an investment company under Section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3).
	(j) o Group, in accordance with §240.13d-1(b)(1)(ii)(J).

ITEM 4	OWNERSHIP:

	As of December 18, 2009, none of the Reporting Persons beneficially owns any shares of Common Stock nor has the power to vote or dispose of any shares of Common Stock.

ITEM 5	OWNERSHIP OF FIVE PERCENT OR LESS OF A CLASS.

	If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than 5 percent of the class of securities, check the following [ X ].


ITEM 6	OWNERSHIP OF MORE THAN FIVE PERCENT ON BEHALF OF ANOTHER PERSON.

	Not Applicable.

ITEM 7	IDENTIFICATION AND CLASSIFICATION OF THE SUBSIDIARY WHICH ACQUIRED THE SECURITY BEING REPORTED ON BY THE PARENT HOLDING COMPANY OR CONTROL PERSON.

	Not Applicable.

ITEM 8	IDENTIFICATION AND CLASSIFICATION OF MEMBERS OF THE GROUP.

	Not Applicable.


ITEM 9	NOTICE OF DISSOLUTION OF GROUP.

	Not Applicable.

ITEM 10	CERTIFICATIONS.

	By signing below each of the Reporting Persons certifies that, to the best of such person’s knowledge and belief, the securities referred to above were acquired and held in the ordinary course of business and were not acquired and were not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect.

SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

December 21, 2009

Southpaw Credit Opportunity Master Fund LP

By: Southpaw GP LLC, its general partner

By:	/s/ Kevin Wyman
Name: Kevin Wyman
Title: Managing Member



Southpaw Asset Management LP

By: Southpaw Holdings LLC, its general partner

By:	/s/ Kevin Wyman
Name: Kevin Wyman
Title: Managing Member



Southpaw Holdings, LLC

By:	/s/ Kevin Wyman
Name: Kevin Wyman
Title: Managing Member


/s/ Kevin Wyman
Kevin Wyman


/s/ Howard Golden
Howard Golden

EXHIBIT INDEX

Exhibit Number	Exhibit

1.	Joint Filing Agreement, dated December 21, 2009, by and among the Reporting Persons.

AVIGEN INC \DE SC 13G/A