UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

WASHINGTON, D.C. 20549

SCHEDULE 13D

(Rule 13d-101)

Under the Securities Exchange Act of 1934

(Amendment No. 8)*

Spark Therapeutics, Inc.

(Name of Issuer)

Common Stock. $0.001 par value

(Title of Class of Securities)

84652J 103

(CUSIP Number)

Jeffrey Kahn

Executive Vice President and General Counsel

The Children’s Hospital of Philadelphia Foundation

3401 Civic Center Boulevard, Philadelphia, PA 19104

(267-426-6148)

(Name, Address and Telephone Number of Person Authorized to Receive Notices and Communications)

October 28, 2019

(Date of Event which Requires Filing of this Statement)

If the filing person has previously filed a statement on Schedule 13G to report the acquisition that is the subject of this Schedule 13D, and is filing this schedule because of §§240.13d-l(e), 240.13d-l(f) or 240.13d-l(g), check the following box. ☐

Note: Schedules filed in paper format shall include a signed original and five copies of the schedule, including all exhibits. See §240.13d-7 for other parties to whom copies are to be sent.

*	The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter disclosures provided in a prior cover page.

The information required on the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).


CUSIP No. 84652J 103		13D		Page 2 of 5 Pages


1		NAMES OF REPORTING PERSONS. IRS. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY). The Children’s Hospital of Philadelphia Foundation EIN 23-2237932
2		CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS) (a) ☐ (b) ☐
3		SEC USE ONLY
4		SOURCE OF FUNDS (SEE INSTRUCTIONS) OO
5		CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) or 2(e) ☐
6		CITIZENSHIP OR PLACE OF ORGANIZATION Pennsylvania


CUSIP No. 84652J 103		13D		Page 3 of 5 Pages

Schedule 13D

This Amendment No. 8 to Schedule 13D (this “Amendment”) amends and supplements the Schedule 13D filed with the Securities and Exchange Commission (the “SEC”) on February 5, 2015, Amendment No. 1 thereto, filed with the SEC on December 22, 2015, Amendment No. 2 thereto, filed with the SEC on January 7, 2016, Amendment 3 thereto, filed with the SEC on July 5, 2016, Amendment 4 thereto, filed with the SEC on August 31, 2016, Amendment 5 thereto, filed with the SEC on June 1, 2017, Amendment 6 thereto, filed with the SEC on March 9, 2018, and Amendment No. 7 thereto, filed with the SEC on March 7, 2019 (collectively the “Schedule 13D”) by, among others, The Children’s Hospital of Philadelphia Foundation (the “Foundation”).

Items 3, 4, and 5 of the Schedule 13D are hereby amended to the extent hereinafter expressly set forth. All capitalized terms used and not expressly defined in this Amendment have the respective meanings ascribed to them in the Schedule 13D.

Item 3. Source and Amount of Funds or Other Consideration.

As of the date of this Amendment, the Foundation beneficially owns a total of 1,629,932 shares of the Issuer’s Common Stock, representing 4.2% of the Issuer’s outstanding Common Stock.

Item 4 Purpose of Transaction.

Item 4 of the Schedule 13D is hereby amended and supplemented as follows:

The Foundation sold 262,228 shares of the Issuer’s Common Stock in market transactions on October 28, 2019.

Item 5. Interest in Securities of the Issuer.

(a) As of the date of this Amendment, the Foundation is the beneficial owner of 1,629,932 shares of Common Stock, consisting of 1,592,729 shares of common stock, 37,203 shares of Common Stock purchasable upon the exercise of a stock option held by Steven Altschuler, M.D., the former Chief Executive Officer of the Foundation and the current Chairman of the Issuer’s Board of Directors. Dr. Altschuler holds these stock options for the benefit of the Foundation.

The Foundation’s Board of Trustees, or a committee designated by the Board of Trustees, has voting and investment power over the shares of Common Stock held by the Foundation, and makes decisions by majority vote. No member of the Board of Trustees or investment committee may act individually to vote or sell shares of Common Stock held by the Foundation, nor does any such member have a veto right concerning the vote or sale of any such common stock. Accordingly, no individual board or committee member is deemed to beneficially own, within the meaning of Rule 13d-3, any shares of Common Stock held by the Foundation solely by virtue of the fact that he or she is a member of the board or the investment committee.


CUSIP No. 84652J 103		13D		Page 4 of 5 Pages

(c) The transactions effected by the Foundation in the Common Stock during the past 60 days are included below. The shares indicated as having been sold were sold by the Foundation pursuant to Rule 144:

Name of Reporting Person

Trade Date

Purchased /
(Sold)

Average Price
per share

The Children’s Hospital of Philadelphia Foundation

October 28, 2019

(262,228

)

109.86

The percentage of outstanding Common Stock of the Issuer which has been reported as being beneficially owned by the Foundation on Line 13 of the cover sheet was calculated based on the 38,486,258 shares of Common Stock reported to be outstanding as of August 2, 2019 on the Issuer’s Quarterly Report on Form 10-Q filed with the SEC on August 8, 2019.


CUSIP No. 84652J 103		13D		Page 5 of 5 Pages

SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

Date: October 28, 2019

THE CHILDREN’S HOSPITAL OF PHILADELPHIA FOUNDATION


By:		/s/ Jeffrey Kahn
		Jeffrey Kahn
		Executive Vice President and General Counsel

NUMBER OF

SHARES BENEFICIALLY

OWNED BY EACH

REPORTING

PERSON

WITH

SOLE VOTING POWER

1,592,729 shares

SHARED VOTING POWER

37,203 shares

SOLE DISPOSITIVE POWER

1,592,729 shares

SHARED DISPOSITIVE POWER

37,203 shares

Spark Therapeutics, Inc. SC 13D/A