Product revenue and reserves - Summary of Product Revenue (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2024	Dec. 31, 2023
Revenue from External Customer [Line Items]
Revenue	$ 83,795	$ 29,065
ZYNTEGLO
Revenue from External Customer [Line Items]
Revenue	62,273	16,692
SKYSONA
Revenue from External Customer [Line Items]
Revenue	9,917	12,373
LYFGENIA
Revenue from External Customer [Line Items]
Revenue	$ 11,605	$ 0

Amount, excluding tax collected from customer, of revenue from satisfaction of performance obligation by transferring promised good or service to customer. Tax collected from customer is tax assessed by governmental authority that is both imposed on and concurrent with specific revenue-producing transaction, including, but not limited to, sales, use, value added and excise.

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+ Details

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