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UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

SCHEDULE 13G

Under the Securities Exchange Act of 1934

(Amendment No. 4)*

Monogram Biosciences, Inc.

(Name of Issuer)

COMMON STOCK

(Title of Class of Securities)

60975U207

(CUSIP Number)

August 31, 2009

(Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

X Rule 13d-1(b)

____ Rule 13d-1(c)

____ Rule 13d-1(d)

*The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.

CUSIP No. 60975U207

____________________________________________________________________________

Names of Reporting Persons.

I.R.S. Identification Nos. of above persons (entities only).

Federated Investors, Inc.

2. Check the Appropriate Box if a Member of a Group (See Instructions)

(a)

(b)

3. SEC Use Only

4. Citizenship or Place of Organization: Pennsylvania

Number of 5. Sole Voting Power -0-

Shares Bene-

ficially by 6. Shared Voting Power

Owned by Each

Reporting 7. Sole Dispositive Power -0-

Person With:

8. Shared Dispositive Power

9. Aggregate Amount Beneficially Owned by Each Reporting Person -0-

10. Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)

11. Percent of Class Represented by Amount in Row (9) 0%

12. Type of Reporting Person (See Instructions) HC

Names of Reporting Persons.

I.R.S. Identification Nos. of above persons (entities only).

Voting Shares Irrevocable Trust

2. Check the Appropriate Box if a Member of a Group (See Instructions)

(a)

(b)

3. SEC Use Only

4. Citizenship or Place of Organization: Pennsylvania

Number of 5. Sole Voting Power -0-

Shares Bene-

ficially by 6. Shared Voting Power

Owned by Each

Reporting 7. Sole Dispositive Power -0-

Person With:

8. Shared Dispositive Power

9. Aggregate Amount Beneficially Owned by Each Reporting Person -0-

10. Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)

11. Percent of Class Represented by Amount in Row (9) 0%

12. Type of Reporting Person (See Instructions) OO

Names of Reporting Persons.

I.R.S. Identification Nos. of above persons (entities only).

John F. Donahue

2. Check the Appropriate Box if a Member of a Group (See Instructions)

(a)

(b)

3. SEC Use Only

4. Citizenship or Place of Organization: United States

Number of 5. Sole Voting Power

Shares Bene-

ficially by 6. Shared Voting Power -0-

Owned by Each

Reporting 7. Sole Dispositive Power

Person With:

8. Shared Dispositive Power -0-

9. Aggregate Amount Beneficially Owned by Each Reporting Person -0-

10. Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)

11. Percent of Class Represented by Amount in Row (9) 0%

12. Type of Reporting Person (See Instructions) IN

Names of Reporting Persons.

I.R.S. Identification Nos. of above persons (entities only).

Rhodora J. Donahue

2. Check the Appropriate Box if a Member of a Group (See Instructions)

(a)

(b)

3. SEC Use Only

4. Citizenship or Place of Organization: United States

Number of 5. Sole Voting Power

Shares Bene-

ficially by 6. Shared Voting Power -0-

Owned by Each

Reporting 7. Sole Dispositive Power

Person With:

8. Shared Dispositive Power -0-

9. Aggregate Amount Beneficially Owned by Each Reporting Person -0-

10. Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)

11. Percent of Class Represented by Amount in Row (9) 0%

12. Type of Reporting Person (See Instructions) IN

Names of Reporting Persons.

I.R.S. Identification Nos. of above persons (entities only).

J. Christopher Donahue

2. Check the Appropriate Box if a Member of a Group (See Instructions)

(a)

(b)

3. SEC Use Only

4. Citizenship or Place of Organization: United States

Number of 5. Sole Voting Power

Shares Bene-

ficially by 6. Shared Voting Power -0-

Owned by Each

Reporting 7. Sole Dispositive Power

Person With:

8. Shared Dispositive Power -0-

9. Aggregate Amount Beneficially Owned by Each Reporting Person -0-

10. Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)

11. Percent of Class Represented by Amount in Row (9) 0%

12. Type of Reporting Person (See Instructions) IN

Item 1.

(a) Name of Issuer

Monogram Biosciences, Inc.

(b) Address of Issuer’s Principal Executive Offices

345 Oyster Point Boulevard

South San Francisco, CA 94080

Item 2.

(a) Name of Person Filing

(b) Address of Principal Business Office or, if none, Residence

Federated Investors Tower, Pittsburgh, PA 15222-3779

(d) Title of Class of Securities

Common Stock

(e) CUSIP Number

60975U207

Item 3. If this statement is filed pursuant to §§240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:

(a) ____ Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o).

(b) ____ Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c).

(d)

____

Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C 80a-8).

(e) ____ An investment adviser in accordance with §240.13d-1(b)(1)(ii)(E);

(f)

____

An employee benefit plan or endowment fund in accordance with §240.13d-1(b)(1)(ii)(F);

(g) __X__ A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);

(h)

____

A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);

(i)

____

A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);

(j) ____ Group, in accordance with §240.13d-1(b)(1)(ii)(J).

Item 4. Ownership.

Provide the following information regarding the aggregate number and percentage of the class of securities of the issuer identified in Item 1.

A. Federated Investors, Inc. (See Footnote 1, next page)

(a) Amount beneficially owned: -0-

(b) Percent of class: 0%

(i) Sole power to vote or to direct the vote -0-

(ii) Shared power to vote or to direct the vote -0-

(iii) Sole power to dispose or to direct the disposition of -0-

(iv) Shared power to dispose or to direct the disposition of -0-

B. Voting Shares Irrevocable Trust

(a) Amount beneficially owned: -0-

(b) Percent of class: 0%

(i) Sole power to vote or to direct the vote -0-

(ii) Shared power to vote or to direct the vote -0-

(iii) Sole power to dispose or to direct the disposition of -0-

(iv) Shared power to dispose or to direct the disposition of -0-

C. John F. Donahue

(a) Amount beneficially owned: -0-

(b) Percent of class: 0%

(i) Sole power to vote or to direct the vote -0-

(ii) Shared power to vote or to direct the vote -0-

(iii) Sole power to dispose or to direct the disposition of -0-

(iv) Shared power to dispose or to direct the disposition of -0-

D. Rhodora J. Donahue

(a) Amount beneficially owned: -0-

(b) Percent of class: 0%

(i) Sole power to vote or to direct the vote -0-

(ii) Shared power to vote or to direct the vote -0-

(iii) Sole power to dispose or to direct the disposition of -0-

(iv) Shared power to dispose or to direct the disposition of -0-

E. J. Christopher Donahue

(a) Amount beneficially owned: -0-

(b) Percent of class: 0%

(i) Sole power to vote or to direct the vote -0-

(ii) Shared power to vote or to direct the vote -0-

(iii) Sole power to dispose or to direct the disposition of -0-

(iv) Shared power to dispose or to direct the disposition of -0-

Instruction. For computations regarding securities which represent a right to acquire an underlying security see §240.13d-3(d)(1).

Item 5. Ownership of Five Percent or Less of a Class

If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than five percent of the class of securities, check the following _X_.

Instruction: Dissolution of a group requires a response to this item.

Item 6. Ownership of More than Five Percent on Behalf of Another Person. NOT APPLICABLE

Item 7. Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on By the Parent Holding Company See Exhibit “1” Attached

Item 8. Identification and Classification of Members of the Group NOT APPLICABLE

Item 9. Notice of Dissolution of Group NOT APPLICABLE

Item 10. Certification

(a) The following certification shall be included if the statement is filed pursuant to §240.13d-1(b):

By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect.

(b) The following certification shall be included if the statement is filed pursuant to §240.13d-1(c):

By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect.

SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

Date: September 10, 2009

By: /s/J. Christopher Donahue

Name/Title: J. Christopher Donahue, as President of Federated Investors, Inc.

Date: September 10, 2009

By: /s/John F. Donahue, individually and as Trustee of Voting Shares Irrevocable Trust, by

J. Christopher Donahue, as attorney-in-fact

Date: September 10, 2009

By: /s/Rhodora J. Donahue, individually and as Trustee of Voting Shares Irrevocable Trust, by

J. Christopher Donahue, as attorney-in-fact

Date: September 10, 2009

By: /s/J. Christopher Donahue

Name/Title: J. Christopher Donahue, individually and as Trustee of Voting Shares Irrevocable Trust

The original statement shall be signed by each person on whose behalf the statement is filed or his authorized representative. If the statement is signed on behalf of a person by his authorized representative other than an executive officer or general partner of the filing person, evidence of the representative’s authority to sign on behalf of such person shall be filed with the statement, provided, however, that a power of attorney for this purpose which is already on file with the Commission may be incorporated by reference. The name and any title of each person who signs the statement shall be typed or printed beneath his signature.

NOTE: Schedules filed in paper format shall include a signed original and five copies of the schedule, including all exhibits. See §240.13d-7 for other parties for whom copies are to be sent.

Attention: Intentional misstatements or omissions of fact constitute Federal criminal violations (See 18 U.S.C. 1001)

EXHIBIT “1”

ITEM 3 CLASSIFICATION OF

REPORTING PERSONS

Identity and Classification of Each Reporting Person

IDENTITY CLASSIFICATION UNDER ITEM 3

Federated Equity Management Company (e) Investment Adviser registered under section 203 of the Investment Advisers Act of 1940

of Pennsylvania

Federated Global Investment (e) Investment Adviser registered under section 203 of the Investment Advisers Act of 1940

Management Corp.

Federated Investors, Inc.

Monogram Biosciences, Inc. SC 13G/A