v3.26.1

Consolidated Statements of Operations and Comprehensive Loss - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2025	Dec. 31, 2024
OPERATING EXPENSES:
Research and development	$ 118,436	$ 119,039
General and administrative	60,601	59,166
Total operating expenses	179,037	178,205
LOSS FROM OPERATIONS:	(179,037)	(178,205)
OTHER (EXPENSE) INCOME, NET:
Fair value change of warrant liabilities	(122,561)	0
Benefit from R&D tax credit	3,747	21,097
Interest income	7,182	8,268
Interest expense	(4,517)	(4,479)
Foreign exchange gains (losses)	3,471	(1,032)
Other income	1,380	823
Total other (expense) income, net	(111,298)	24,677
Loss before income taxes	(290,335)	(153,528)
Income tax benefit (expense)	2,473	(1,594)
Net loss	$ (287,862)	$ (155,122)
Net loss per share attributable to ordinary shareholders - basic (in dollars per share)	$ (3.08)	$ (2.30)
Net loss per share attributable to ordinary shareholders - diluted (in dollars per share)	$ (3.08)	$ (2.30)
Weighted average ordinary shares outstanding - basic (in shares)	93,504,836	67,482,902
Weighted average ordinary shares outstanding - diluted (in shares)	93,504,836	67,482,902
Net loss	$ (287,862)	$ (155,122)
Other comprehensive loss:
Foreign exchange translation adjustment	1,405	732
Comprehensive loss	$ (286,457)	$ (154,390)

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