CASPER MARC N 4

4 · THERMO FISHER SCIENTIFIC INC. · Filed Mar 5, 2026

Insider Transaction Report

Form 4

Period: 2026-03-03

THERMO FISHER SCIENTIFIC INC.TMO

CASPER MARC N

DirectorChairman & CEO

Transactions

Exercise/Conversion
Common Stock
2026-03-03$309.63/sh+5,000$1,548,150→ 128,925.358 total
Sale
Common Stock
[F1][F2]
2026-03-03$495.29/sh−360$178,304→ 128,565.358 total
Sale
Common Stock
[F1][F3]
2026-03-03$496.84/sh−480$238,483→ 128,085.358 total
Sale
Common Stock
[F1][F4]
2026-03-03$498.14/sh−680$338,735→ 127,405.358 total
Sale
Common Stock
[F1][F5]
2026-03-03$499.75/sh−240$119,940→ 127,165.358 total
Sale
Common Stock
[F1][F6]
2026-03-03$500.55/sh−382$191,210→ 126,783.358 total
Sale
Common Stock
[F1][F7]
2026-03-03$501.95/sh−360$180,702→ 126,423.358 total
Sale
Common Stock
[F1][F8]
2026-03-03$502.59/sh−120$60,311→ 126,303.358 total
Sale
Common Stock
[F1][F9]
2026-03-03$504.06/sh−120$60,487→ 126,183.358 total
Sale
Common Stock
[F1][F10]
2026-03-03$506.74/sh−448$227,020→ 125,735.358 total
Sale
Common Stock
[F1][F11]
2026-03-03$507.90/sh−931$472,855→ 124,804.358 total
Sale
Common Stock
[F1][F12]
2026-03-03$508.95/sh−759$386,293→ 124,045.358 total
Sale
Common Stock
[F1][F13]
2026-03-03$509.62/sh−120$61,154→ 123,925.358 total
Exercise/Conversion
Common Stock
2026-03-04$309.63/sh+5,000$1,548,150→ 128,925.358 total
Sale
Common Stock
[F1][F14]
2026-03-04$509.89/sh−447$227,921→ 128,478.358 total
Sale
Common Stock
[F1][F15]
2026-03-04$510.71/sh−678$346,261→ 127,800.358 total
Sale
Common Stock
[F1][F16]
2026-03-04$511.80/sh−1,370$701,166→ 126,430.358 total
Sale
Common Stock
[F1][F17]
2026-03-04$512.92/sh−1,241$636,534→ 125,189.358 total
Sale
Common Stock
[F1][F18]
2026-03-04$513.63/sh−815$418,608→ 124,374.358 total
Sale
Common Stock
[F1][F19]
2026-03-04$514.86/sh−212$109,150→ 124,162.358 total
Sale
Common Stock
[F1][F20]
2026-03-04$515.77/sh−119$61,377→ 124,043.358 total
Sale
Common Stock
[F1][F21]
2026-03-04$516.75/sh−118$60,977→ 123,925.358 total
Exercise/Conversion
Stock Option (Right to Buy)
[F24]
2026-03-03−5,000→ 49,550 total
Exercise: $309.63Exp: 2027-02-25→ Common Stock (5,000 underlying)
Exercise/Conversion
Stock Option (Right to Buy)
[F24]
2026-03-04−5,000→ 44,550 total
Exercise: $309.63Exp: 2027-02-25→ Common Stock (5,000 underlying)

Holdings

Common Stock
[F22]
(indirect: By Trust)
11,300
Common Stock
(indirect: By Floral Park Associates, Inc.)
14,608
Common Stock
[F23]
(indirect: By Trust)
5,000

Footnotes (24)

[F1]The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on November 11, 2025.
[F10]The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $506.40 to $507.38, inclusive.
[F11]The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $507.41 to $508.31, inclusive.
[F12]The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $508.57 to $509.28, inclusive.
[F13]The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $509.62 to $509.63, inclusive.
[F14]The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $509.283 to $510.22, inclusive.
[F15]The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $510.32 to $511.277, inclusive.
[F16]The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $511.323 to $512.303, inclusive.
[F17]The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $512.34 to $513.33, inclusive.
[F18]The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $513.341 to $514.328, inclusive.
[F19]The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $514.383 to $515.373, inclusive.
[F2]The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $495.08 to $495.46, inclusive. The reporting person undertakes to provide to Thermo Fisher Scientific Inc. ("TMO"), any security holder of TMO or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes (2), (3), (4), (5), (6), (7), (8), (9), (10), (11), (12), (13), (14), (15), (16), (17), (18), (19), (20), and (21) to this Form 4.
[F20]The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $515.378 to $516.065, inclusive.
[F21]The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $516.57 to $517.046, inclusive.
[F22]The reporting person disclaims beneficial ownership of the securities reported herein as indirectly beneficially owned, except to the extent of any pecuniary interest therein.
[F23]The reporting person disclaims beneficial ownership of the securities reported herein as indirectly beneficially owned, except to the extent of any pecuniary interest therein.
[F24]The option vested in four equal installments on February 25, 2021, 2022, 2023, and 2024.
[F3]The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $496.43 to $497.37, inclusive.
[F4]The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $497.80 to $498.70, inclusive.
[F5]The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $499.36 to $500.14, inclusive.
[F6]The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $500.47 to $501.44, inclusive.
[F7]The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $501.56 to $502.36, inclusive.
[F8]The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $502.59 to $502.60, inclusive.
[F9]The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $504.06 to $504.07, inclusive.

Signature

/s/ Melodie T. Morin, Attorney-in-Fact for Marc N. Casper|2026-03-05

Documents

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form4.xmlPrimary
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