UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

________________________________________________________

FORM 10-Q

________________________________________________________

(Mark One)


☒			QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

For the quarterly period ended ~~June~~September 2726, 2025


☐			TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

For the transition period from to

Commission File Number: 001-08089

DANAHER CORPORATION

(Exact name of registrant as specified in its charter)


Delaware		59-1995548
(State of Incorporation)		(I.R.S. Employer Identification Number)

2200 Pennsylvania Avenue, N.W., Suite 800W		20037-1701
Washington,	DC
(Address of Principal Executive Offices)		(Zip Code)

Registrant’s telephone number, including area code: 202-828-0850


Title of each class	Trading Symbol(s)	Name of each exchange on which registered
Common stock, $0.01 par value	DHR	New York Stock Exchange
0.200% Senior Notes due 2026	DHR/26	New York Stock Exchange
2.100% Senior Notes due 2026	DHR 26	New York Stock Exchange
1.200% Senior Notes due 2027	DHR/27	New York Stock Exchange
0.450% Senior Notes due 2028	DHR/28	New York Stock Exchange
2.500% Senior Notes due 2030	DHR 30	New York Stock Exchange
0.750% Senior Notes due 2031	DHR/31	New York Stock Exchange
1.350% Senior Notes due 2039	DHR/39	New York Stock Exchange
1.800% Senior Notes due 2049	DHR/49	New York Stock Exchange

Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports) and (2) has been subject to such filing requirements for the past 90 days. Yes ☒ No ☐

Indicate by check mark whether the registrant has submitted electronically every Interactive Data File required to be submitted pursuant to Rule 405 of Regulation S-T during the preceding 12 months (or for such shorter period that the registrant was required to submit such files). Yes ☒ No ☐

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company, or an emerging growth company. See the definitions of “large accelerated filer,” “accelerated filer,” “smaller reporting company” and “emerging growth company” in Rule 12b-2 of the Exchange Act.

Large Accelerated Filer

☒

Accelerated Filer

☐

Non-accelerated Filer

☐

Smaller Reporting Company

☐

Emerging Growth Company

☐

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐

Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act) Yes ☐ No ☒

The number of shares of common stock outstanding at ~~July~~October 1716, 2025 was ~~716~~706,~~051~~349,~~590~~563.

DANAHER CORPORATION

INDEX

FORM 10-Q

		Page
PART I -	FINANCIAL INFORMATION
Item 1.	Financial Statements
	Consolidated Condensed Balance Sheets	1
	Consolidated Condensed Statements of Earnings	2
	Consolidated Condensed Statements of Comprehensive Income	3
	Consolidated Condensed Statements of Stockholders’ Equity	4
	Consolidated Condensed Statements of Cash Flows	5
	Notes to Consolidated Condensed Financial Statements	6
Item 2.	Management’s Discussion and Analysis of Financial Condition and Results of Operations	2325
Item 3.	Quantitative and Qualitative Disclosures About Market Risk	3841
Item 4.	Controls and Procedures	3841
PART II -	OTHER INFORMATION
Item 1.	Legal Proceedings	3942
Item 1A.	Risk Factors	3942
Item 2.	Unregistered Sales of Equity Securities and Use of Proceeds	3943
Item 5.	Other Information	4043
Item 6.	Exhibits	4144
	Signatures	4245

Table of Contents

DANAHER CORPORATION AND SUBSIDIARIES

CONSOLIDATED CONDENSED BALANCE SHEETS

($ in millions, except per share amount)

(unaudited)

	June 27, 2025		December 31, 2024
	September 26, 2025		December 31, 2024
ASSETS
Current assets:
Cash and equivalents	$	21,~~957~~528	$	2,078
Trade accounts receivable, less allowance for doubtful accounts of $120 and $113, respectively	3,564		3,537
Trade accounts receivable, less allowance for doubtful accounts of $119 and $113, respectively	3,755		3,537
Inventories:
Finished goods	1,~~383~~373		1,145
Work in process	~~525~~526		465
Raw materials	~~781~~775		720
Total inventories	2,~~689~~674		2,330
Prepaid expenses and other current assets	1,~~789~~649		1,552
Total current assets	109,~~999~~606		9,497
Property, plant and equipment, net of accumulated depreciation of $4,561 and $4,101, respectively	5,309		4,990
Property, plant and equipment, net of accumulated depreciation of $4,666 and $4,101, respectively	5,376		4,990
Other long-term assets	3,~~692~~870		3,990
Goodwill	42,~~991~~948		40,497
Other intangible assets, net	18,~~629~~097		18,568
Total assets	$	8179,~~620~~897	$	77,542
LIABILITIES AND STOCKHOLDERS’ EQUITY
Current liabilities:
Notes payable and current portion of long-term debt	$	~~502~~23	$	505
Trade accounts payable	1,~~725~~698		1,753
Accrued expenses and other liabilities	4,~~565~~603		4,540
Total current liabilities	6,~~792~~324		6,798
Other long-term liabilities	5,~~633~~660		5,694
Long-term debt	16,~~853~~833		15,500
Stockholders’ equity:
Common stock - $0.01 par value, 2.0 billion shares authorized; 885.9 million issued and 715.9 million outstanding as of June 27, 2025; 884.3 million issued and 719.1 million outstanding as of December 31, 2024	9		9
Common stock - $0.01 par value, 2.0 billion shares authorized; 886.3 million issued and 706.3 million outstanding as of September 26, 2025; 884.3 million issued and 719.1 million outstanding as of December 31, 2024	9		9
Additional paid-in capital	1617,~~960~~076		16,727
Treasury stock	(911,~~305~~344)		(8,163)
Retained earnings	45,~~239~~920		44,188
Accumulated other comprehensive income (loss)	(~~569~~590)		(3,218)
Total Danaher stockholders’ equity	5251,~~334~~071		49,543
Noncontrolling interests	89		7
Total stockholders’ equity	5251,~~342~~080		49,550
Total liabilities and stockholders’ equity	$	8179,~~620~~897	$	77,542

See the accompanying Notes to the Consolidated Condensed Financial Statements.

Table of Contents

DANAHER CORPORATION AND SUBSIDIARIES

CONSOLIDATED CONDENSED STATEMENTS OF EARNINGS

($ and shares in millions, except per share amounts)

(unaudited)

Three-Month Period Ended

~~Six~~Nine-Month Period Ended

June 27, 2025

June 28, 2024

June 27, 2025

June 28, 2024

September 26, 2025

September 27, 2024

September 26, 2025

September 27, 2024

Sales

56,~~936~~053

5,~~743~~798

1117,~~677~~730

1117,~~539~~337

Cost of sales

(2,~~413~~530)

(2,~~315~~397)

(47,~~643~~173)

(47,~~624~~021)

Gross profit

3,523

3,~~428~~401

710,~~034~~557

610,~~915~~316

Operating costs:

Selling, general and administrative expenses

(21,~~360~~991)

(12,~~869~~060)

(46,~~218~~209)

(35,~~676~~736)

Research and development expenses

(~~403~~378)

(~~391~~383)

(~~782~~1,160)

(~~759~~1,142)

Operating profit

~~760~~1,154

~~1,168~~958

23,~~034~~188

23,~~480~~438

Nonoperating income (expense):

Other income (expense), net

(4214)

~~(59)~~102

(~~121~~135)

~~(95)~~7

Interest expense

(7167)

(6587)

(~~143~~210)

(~~130~~217)

Interest income

394

1417

99103

Earnings before income taxes

~~655~~1,076

~~1,083~~977

12,~~784~~860

23,~~354~~331

Income taxes

(~~100~~168)

(~~176~~159)

(~~275~~443)

(~~359~~518)

Net earnings

~~555~~908

~~907~~818

12,~~509~~417

12,~~995~~813

Net earnings per common share:

Basic

01.7728

1.2313

23.1138

(a)

23.7083

Diluted

01.7727

1.2212

23.1037

(a)

23.6880

(a)

Average common stock and common equivalent shares outstanding:

Basic

~~716~~710.57

~~737~~723.60

~~716~~714.45

~~739~~733.18

Diluted

~~719~~713.17

~~742~~729.4

~~719~~717.9

~~745~~740.51

(a) Net earnings per common share amounts for the relevant three-month periods do not add to the ~~six~~nine-month period amount due to rounding.

See the accompanying Notes to the Consolidated Condensed Financial Statements.

Table of Contents

DANAHER CORPORATION AND SUBSIDIARIES

CONSOLIDATED CONDENSED STATEMENTS OF COMPREHENSIVE INCOME

($ in millions)

(unaudited)

Three-Month Period Ended

~~Six~~Nine-Month Period Ended

June 27, 2025

June 28, 2024

June 27, 2025

June 28, 2024

September 26, 2025

September 27, 2024

September 26, 2025

September 27, 2024

Net earnings

~~555~~908

~~907~~818

12,~~509~~417

12,~~995~~813

Other comprehensive income (loss), net of income taxes:

Foreign currency translation adjustments

~~1,028~~(71)

~~121~~1,216

2,~~477~~406

~~(827)~~389

Pension and postretirement plan benefit adjustments

Cash flow hedge adjustments

1348

3063

~~169~~217

~~(20)~~43

Total other comprehensive income (loss), net of income taxes

~~1,043~~(21)

~~153~~1,281

2,~~649~~628

~~(843)~~438

Comprehensive income

~~1,598~~887

12,~~060~~099

45,~~158~~045

13,~~152~~251

See the accompanying Notes to the Consolidated Condensed Financial Statements.

Table of Contents

DANAHER CORPORATION AND SUBSIDIARIES

CONSOLIDATED CONDENSED STATEMENTS OF STOCKHOLDERS’ EQUITY

($ in millions)

(unaudited)

	Three-Month Period Ended				~~Six~~Nine-Month Period Ended
	June 27, 2025		June 28, 2024		June 27, 2025		June 28, 2024
	September 26, 2025		September 27, 2024		September 26, 2025		September 27, 2024
Common stock:
Balance, beginning and end of period	$	9	$	9	$	9	$	9
Additional paid-in capital:
Balance, beginning of period	$	16,~~845~~960	$	16,~~314~~490	$	16,727	$	16,170
Common stock-based award activity	~~115~~116		~~173~~151		~~233~~349		~~317~~468
Acquisition of controlling interests	—		3—		—		3
Balance, end of period	$	1617,~~960~~076	$	16,~~490~~641	$	1617,~~960~~076	$	16,~~490~~641
Treasury stock:
Balance, beginning of period	$	(9,~~306~~305)	$	(26,~~099~~684)	$	(8,163)	$	(2,019)
Repurchase of common stock, including excise tax	7(2,030)		(~~4,576~~646)		(13,~~082~~112)		(45,~~576~~222)
Common stock-based award activity	(69)		(97)		(6069)		(8996)
Balance, end of period	$	(911,~~305~~344)	$	(67,~~684~~337)	$	(911,~~305~~344)	$	(67,~~684~~337)
Retained earnings:
Balance, beginning of period	$	4445,~~913~~239	$	4142,~~962~~673	$	44,188	$	41,074
Net earnings	~~555~~908		~~907~~818		12,~~509~~417		12,~~995~~813
Common stock dividends declared	(~~229~~227)		(~~196~~195)		(~~458~~685)		(~~396~~591)
Balance, end of period	$	45,~~239~~920	$	4243,~~673~~296	$	45,~~239~~920	$	4243,~~673~~296
Accumulated other comprehensive income (loss):
Balance, beginning of period	$	(~~1,612~~569)	$	(2,~~744~~591)	$	(3,218)	$	(1,748)
Other comprehensive income (loss)	~~1,043~~(21)		~~153~~1,281		2,~~649~~628		~~(843)~~438
Balance, end of period	$	(~~569~~590)	$	(21,~~591~~310)	$	(~~569~~590)	$	(21,~~591~~310)
Noncontrolling interests:
Balance, beginning of period	$	8	$	5	$	7	$	4
Change in noncontrolling interests	—1		—1		12		12
Balance, end of period	$	89	$	56	$	89	$	56
Total stockholders’ equity, end of period	$	5251,~~342~~080	$	4951,~~902~~305	$	5251,~~342~~080	$	4951,~~902~~305

See the accompanying Notes to the Consolidated Condensed Financial Statements.

Table of Contents

DANAHER CORPORATION AND SUBSIDIARIES

CONSOLIDATED CONDENSED STATEMENTS OF CASH FLOWS

($ in millions)

(unaudited)

	Six-Month Period Ended
	Nine-Month Period Ended
	June 27, 2025		June 28, 2024
	September 26, 2025		September 27, 2024
Cash flows from operating activities:
Net earnings	$	12,~~509~~417	$	12,~~995~~813
Noncash items:
Depreciation	~~366~~555		~~357~~534
Amortization of intangible assets	~~836~~1,269		~~809~~1,223
Amortization of acquisition-related inventory fair value step-up	—		25
Stock-based compensation expense	~~152~~235		~~147~~231
Investment losses and pretax gain on sale of product line	~~125~~140		96(7)
Impairment charges	~~447~~548		—222
Change in trade accounts receivable, net	~~134~~(65)		~~590~~482
Change in inventories	(~~248~~242)		(~~152~~117)
Change in trade accounts payable	(~~111~~134)		(~~104~~186)
Change in prepaid expenses and other assets	(9953)		~~215~~299
Change in accrued expenses and other liabilities	(~~474~~371)		(~~822~~850)
Net cash provided by operating activities	24,~~637~~299		34,~~156~~669
Cash flows from investing activities:
Cash paid for acquisitions	—		(12525)
Payments for additions to property, plant and equipment	(~~493~~785)		(~~578~~876)
Proceeds from sales of property, plant and equipment	10		112
Payments for purchases of investments	(5079)		(~~127~~188)
Proceeds from sales of investments	1012		9251
Proceeds from sale of product line	9		—
All other investing activities	1421		2639
Total cash used in investing activities	(~~500~~812)		(~~681~~1,287)
Cash flows from financing activities:
Proceeds from the issuance of common stock in connection with stock-based compensation, net	1439		76143
Payment of dividends	(~~423~~652)		(~~377~~573)
Net borrowings (maturities longer than 90 days)	4		—
Net proceeds from borrowings (maturities of 90 days or less)	22		1
Net (repayments of) proceeds from borrowings (maturities of 90 days or less)	(1)		15
Borrowings (maturities longer than 90 days)	4		—
Net repayments of borrowings (maturities longer than 90 days)	—		(974)
Repayments of borrowings (maturities longer than 90 days)	(500)		(974)
Payments for repurchase of common stock	(13,~~078~~088)		(45,~~530~~170)
All other financing activities	(18108)		(58120)
Total cash used in financing activities	(14,~~502~~283)		(56,~~848~~693)
Effect of exchange rate changes on cash and equivalents	~~244~~246		~~(117)~~74
Net change in cash and equivalents	~~879~~(550)		(3,~~490~~237)
Beginning balance of cash and equivalents	2,078		5,864
Ending balance of cash and equivalents	$	21,~~957~~528	$	2,~~374~~627
Supplemental disclosures:
Cash interest payments	$	~~149~~231	$	~~176~~280
Cash income tax payments	~~531~~808		~~618~~933

See the accompanying Notes to the Consolidated Condensed Financial Statements.

Table of Contents

DANAHER CORPORATION AND SUBSIDIARIES

NOTES TO CONSOLIDATED CONDENSED FINANCIAL STATEMENTS

(unaudited)

NOTE 1. GENERAL

The Consolidated Condensed Financial Statements included herein have been prepared by Danaher Corporation (“Danaher” or the “Company”) without audit, pursuant to the rules and regulations of the Securities and Exchange Commission (“SEC”). In this quarterly report, the terms “Danaher” or the “Company” refer to Danaher Corporation, Danaher Corporation and its consolidated subsidiaries, or the consolidated subsidiaries of Danaher Corporation, as the context requires. Certain information and footnote disclosures normally included in financial statements prepared in accordance with accounting principles generally accepted in the United States (“U.S. GAAP”) have been condensed or omitted pursuant to SEC rules and regulations; however, the Company believes that the disclosures are adequate to make the information presented not misleading. The Consolidated Condensed Financial Statements included herein should be read in conjunction with the financial statements as of and for the year ended December 31, 2024 and the Notes thereto included in the Company’s 2024 Annual Report on Form 10-K filed on February 20, 2025 (the “2024 Annual Report”).

In the opinion of the Company, the accompanying financial statements contain all adjustments (consisting of only normal recurring accruals) necessary to present fairly the financial position of the Company as of ~~June~~September 2726, 2025 and December 31, 2024, its results of operations for the three and ~~six~~nine-month periods ended ~~June~~September 2726, 2025 and ~~June~~September 2827, 2024 and its cash flows for each of the ~~six~~nine-month periods then ended.

There have been no changes to the Company’s significant accounting policies described in the Company’s 2024 Annual Report that have a material impact on the Company’s Consolidated Condensed Financial Statements and the related Notes. Reclassifications of certain prior year amounts have been made to conform to the current year presentation.

Accounting Standards Recently Adopted—In November 2023, the Financial Accounting Standards Board (“FASB”) issued Accounting Standards Update (“ASU”) 2023-07, Improvements to Reportable Segment Disclosures. The ASU requires additional disclosures about reportable segments’ significant expenses on an interim and annual basis. The Company adopted the ASU effective January 1, 2024 on a retrospective basis. Refer to Note 5 for additional segment disclosures.

In December 2023, the FASB issued ASU 2023-09, Improvements to Income Tax Disclosures. The ASU expands disclosures in the income tax rate reconciliations table and cash taxes paid. The Company adopted the ASU effective January 1, 2025. This accounting standard will increase the tax disclosures in the Company’s annual reporting but has no impact on reported income tax expense or related tax assets or liabilities.

Accounting Standards Not Yet Adopted—In November 2024, the FASB issued ASU 2024-03, Disaggregation of Income Statement Expenses. The ASU requires disclosure of disaggregated information about certain income statement expenses, including specific expense categories. The ASU is effective for annual periods beginning after December 15, 2026 and for interim periods within fiscal years beginning after December 15, 2027. ~~The~~This ~~Company~~accounting ~~is assessing the impact of the ASU on the Company’s disclosures and expects that the~~ standard will increase disclosures in the Company’s annual and interim reporting when adopted.

~~Prepaid~~In ~~Expenses~~July ~~and~~2025, ~~Other~~the ~~Current~~FASB ~~Assets—Prepaid~~issued ~~expenses~~ASU ~~and~~2025-05, ~~other~~Measurement ~~current~~of ~~assets~~Credit ~~primarily~~Loss ~~result~~for ~~from~~Accounts ~~advance~~Receivable ~~payments~~and toContract ~~vendors~~Assets. The ~~for~~ASU ~~goods~~provides ~~and~~a ~~services~~practical ~~which~~expedient ~~are~~for ~~capitalized~~the ~~until~~calculation ~~the~~of ~~related~~current ~~goods~~expected ~~are~~credit ~~received~~losses orfor ~~services~~current ~~are~~accounts ~~performed~~receivable and ~~advance~~contract ~~payments~~assets, allowing entities to ~~tax~~assume ~~authorities. The~~that ~~Company’s~~current ~~prepaid~~conditions ~~expenses~~as ~~and~~of ~~other~~the ~~current~~balance ~~assets~~sheet ~~balances~~date aswill ofpersist ~~June 27,~~through ~~2025~~the ~~and~~forecast ~~December 31,~~period. The ~~2024~~ASU ~~are~~is ~~primarily~~effective ~~comprised~~for ofinterim ~~prepaid~~and ~~expenses~~annual ofreporting ~~$747 million~~periods ~~and~~beginning ~~$620 million,~~after ~~respectively~~December 15, ~~and~~2025. The ~~taxes~~Company ~~receivable~~is ~~for~~assessing ~~income~~the ~~and~~impact ~~other~~of ~~taxes~~the ~~and~~ASU ~~deferred~~on ~~tax~~its ~~assets~~consolidated offinancial ~~$952 million~~statements and ~~$853 million,~~related ~~respectively~~disclosures.

~~Operating~~In ~~Leases—As~~September ~~of June 27,~~ 2025 ~~and December 31~~, ~~2024,~~the ~~operating~~FASB ~~lease~~issued ~~right~~ASU 2025-~~of-use~~06, ~~assets~~Targeted ~~where~~Improvements ~~the~~to ~~Company was~~ the ~~lessee~~Accounting ~~were~~for ~~approximately~~Internal-Use $1Software.1 The ~~billion~~ASU ~~and~~updates ~~are~~the ~~included~~requirements ~~within~~for ~~other~~capitalization ~~long~~of internal-~~term~~use ~~assets~~software, inremoving ~~the~~all ~~accompanying~~reference ~~Consolidated~~to ~~Condensed~~prescriptive ~~Balance~~and ~~Sheets. The~~sequential ~~associated~~software ~~operating~~development ~~lease~~stages. The ~~liabilities~~ASU ~~were~~is ~~approximately~~effective ~~$1.2~~for ~~billion~~annual ~~and~~periods ~~$1.1~~beginning ~~billion~~after asDecember ~~of June 27~~15, ~~2025~~2027 and ~~December 31,~~for ~~2024,~~interim ~~respectively,~~periods ~~and~~within ~~are~~those ~~included~~fiscal inyears. The ~~accrued~~Company ~~expenses~~is ~~and~~assessing ~~other~~the ~~liabilities~~impact ~~and~~of ~~other~~the ~~long-term~~ASU ~~liabilities~~on inits ~~the~~consolidated ~~accompanying~~financial ~~Consolidated~~statements ~~Condensed~~and ~~Balance~~related ~~Sheets~~disclosures.

~~Contingencies~~Prepaid Expenses and Other Current Assets—~~The~~Prepaid ~~Company~~expenses ~~reviews~~and ~~the~~other ~~adequacy~~current ofassets ~~its~~primarily ~~legal~~result ~~reserves~~from onadvance apayments ~~quarterly~~to ~~basis~~vendors for goods and ~~establishes~~services ~~reserves~~which ~~for~~are ~~loss~~capitalized ~~contingencies~~until ~~that~~the related goods are ~~both~~received ~~probable~~or ~~and~~services ~~reasonably~~are ~~estimable. For~~performed aand ~~further~~advance ~~description~~payments ofto ~~the~~tax authorities. The Company’s ~~litigation~~prepaid expenses and ~~contingencies,~~other ~~refer~~current toassets ~~Note~~balances 17as of ~~the~~September 26, ~~Company’s~~2025 ~~financial~~and ~~statements~~December 31, as2024 are primarily comprised of ~~and~~prepaid ~~for~~expenses ~~the~~of ~~year~~$639 million ~~ended~~and ~~December~~$620 31million, ~~2024~~respectively, ~~included~~and intaxes ~~the~~receivable ~~Company’s~~for ~~2024~~income ~~Annual~~and ~~Report~~other taxes and deferred tax assets of $920 million and $853 million, respectively.

Table of Contents

Operating Leases—As of September 26, 2025 and December 31, 2024, operating lease right-of-use assets where the Company was the lessee were approximately $1.2 billion and $1.1 billion, respectively, and are included within other long-term assets in the accompanying Consolidated Condensed Balance Sheets. The associated operating lease liabilities were approximately $1.3 billion and $1.1 billion as of September 26, 2025 and December 31, 2024, respectively, and are included in accrued expenses and other liabilities and other long-term liabilities in the accompanying Consolidated Condensed Balance Sheets.

U.S. Pension Plan Buy-In—In September 2025, the Company entered into a $349 million insurance buy-in contract for a portion of the benefit obligations under the U.S. defined benefit pension plan, which was funded from existing pension plan assets without an adjustment to the benefit obligations. Insurance buy-in contracts are annuity contracts that are expected to provide an income stream to cover the cash flows associated with future contracted payments for the plan population. However, the benefit obligation remains with the plan and the Company. This contract is issued by a third-party insurance company that has no affiliation with the Company or the plan.

NOTE 2. ACQUISITIONS

For a description of the Company’s acquisition activity for the year ended December 31, 2024, reference is made to the financial statements as of and for the year ended December 31, 2024 and Note 2 thereto included in the Company’s 2024 Annual Report. There were no acquisitions during the ~~six~~nine-month period ended ~~June~~September 2726, 2025.

The Company continually evaluates potential acquisitions that either strategically fit with the Company’s existing portfolio or expand the Company’s portfolio into a new and attractive business area. The Company has completed a number of acquisitions that have been accounted for as purchases and have resulted in the recognition of goodwill in the Company’s financial statements. This goodwill arises because the purchase prices for these businesses exceed the fair value of acquired identifiable net assets due to the purchase prices reflecting a number of factors including the future earnings and cash flow potential of these businesses, the multiple to earnings, cash flow and other factors at which similar businesses have been purchased by other acquirers, the competitive nature of the processes by which the Company acquired the businesses, the avoidance of the time and costs which would be required (and the associated risks that would be encountered) to enhance the Company’s existing product offerings to key target markets and enter into new and profitable businesses and the complementary strategic fit and resulting synergies these businesses bring to existing operations.

The Company makes an initial allocation of the purchase price at the date of acquisition based upon its understanding of the fair value of the acquired assets and assumed liabilities. The Company obtains the information used for the purchase price allocation during due diligence and through other sources. In the months after closing, as the Company obtains additional information about the acquired assets and liabilities, including through tangible and intangible asset appraisals, and learns more about the newly acquired business, it is able to refine the estimates of fair value and more accurately allocate the purchase price. The fair values of acquired intangibles are determined based on estimates and assumptions that are deemed reasonable by the Company. Significant assumptions include the discount rates and certain assumptions that form the basis of the forecasted results of the acquired business including earnings before interest, taxes, depreciation and amortization (“EBITDA”), revenue, revenue growth rates, royalty rates and technology obsolescence rates. These assumptions are forward looking and could be affected by future economic and market conditions. The Company engages third-party valuation specialists who review the Company’s critical assumptions and calculations of the fair value of acquired intangible assets in connection with significant acquisitions. Only facts and circumstances that existed as of the acquisition date are considered for subsequent adjustment.

Pro Forma Financial Information

The unaudited pro forma information for the periods set forth below gives effect to the 2024 acquisitions as if they had occurred as of the beginning of the comparable prior annual reporting period, including the results from operations for the acquired businesses as well as the impact of assumed financing of the transaction and the impact of the purchase price allocation (including the amortization of acquired intangible assets). The pro forma information is presented for informational purposes only and is not necessarily indicative of the results of operations that actually would have been achieved had the acquisitions been consummated as of that time ($ in millions, except per share amounts):

Three-Month Period Ended

~~Six~~Nine-Month Period Ended

June 27, 2025

June 28, 2024

June 27, 2025

June 28, 2024

September 26, 2025

September 27, 2024

September 26, 2025

September 27, 2024

Sales

56,~~936~~053

5,~~769~~799

1117,~~677~~730

1117,~~582~~381

Net earnings

~~555~~908

~~898~~818

12,~~509~~417

2,~~003~~821

Diluted net earnings per common share

01.7727

1.2112

23.1037

23.6981

The ~~six~~nine-month period ended ~~June~~September 2827, 2024 unaudited pro forma net earnings were adjusted to exclude the pretax impact of a $25 million nonrecurring acquisition date fair value adjustment to inventory.

NOTE 3. NET EARNINGS PER COMMON SHARE

Basic net earnings per common share (“EPS”) is calculated by taking net earnings divided by the weighted average number of common shares outstanding for the applicable period. Diluted net EPS is computed by taking net earnings increased by the number of additional shares that would have been outstanding had the potentially dilutive common shares been issued and reduced by the number of shares the Company could have repurchased with the proceeds from the issuance of the potentially dilutive shares. For the three-month periods ended June 27, 2025 and June 28, 2024, approximately 8.3 million and 2.9 million options, respectively, and for the six-month periods ended June 27, 2025 and June 28, 2024, approximately 6.8 million and 1.7 million options, respectively, to purchase shares were excluded from the diluted EPS calculation, as the impact of their inclusion would have been anti-dilutive. Basic and diluted EPS are computed independently for each quarter and year-to-date period, and each period involves the use of different weighted average share count figures. As a result, and after factoring in the effect of rounding to the nearest cent per share, the sum of prior quarterly EPS figures may not equal year-to-date EPS.

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NOTE 3. NET EARNINGS PER COMMON SHARE

Basic net earnings per common share (“EPS”) is calculated by taking net earnings divided by the weighted average number of common shares outstanding for the applicable period. Diluted net EPS is computed by taking net earnings increased by the number of additional shares that would have been outstanding had the potentially dilutive common shares been issued and reduced by the number of shares the Company could have repurchased with the proceeds from the issuance of the potentially dilutive shares. For the three-month periods ended September 26, 2025 and September 27, 2024, approximately 6.9 million and 305 thousand options, respectively, and for the nine-month periods ended September 26, 2025 and September 27, 2024, approximately 6.8 million and 1.2 million options, respectively, to purchase shares were excluded from the diluted EPS calculation, as the impact of their inclusion would have been anti-dilutive. Basic and diluted EPS are computed independently for each quarter and year-to-date period, and each period involves the use of different weighted average share count figures. As a result, and after factoring in the effect of rounding to the nearest cent per share, the sum of prior quarterly EPS figures may not equal year-to-date EPS.

Information related to the calculation of net earnings per common share is summarized as follows ($ and shares in millions, except per share amounts):

	Three-Month Period Ended				~~Six~~Nine-Month Period Ended
	June 27, 2025		June 28, 2024		June 27, 2025		June 28, 2024
	September 26, 2025		September 27, 2024		September 26, 2025		September 27, 2024
Numerator:
Net earnings	$	~~555~~908	$	~~907~~818	$	12,~~509~~417	$	12,~~995~~813
Denominator:
Weighted average common shares outstanding used in Basic EPS	~~716~~710.57		~~737~~723.60		~~716~~714.45		~~739~~733.18
Incremental common shares from:
Assumed exercise of dilutive options and vesting of dilutive restricted stock units (“RSUs”) and performance stock units (“PSUs”)	23.60		46.84		3.54		6.43
Weighted average common shares outstanding used in Diluted EPS	~~719~~713.17		~~742~~729.4		~~719~~717.9		~~745~~740.51
Basic EPS	$	01.7728	$	1.2313	$	23.1138	$	23.7083
Diluted EPS	$	01.7727	$	1.2212	$	23.1037	$	23.6880

NOTE 4. REVENUE

The following tables present the Company’s revenues disaggregated by geographical region and revenue type for the three and six-month periods ended June 27, 2025 and June 28, 2024 ($ in millions). Sales taxes and other usage-based taxes collected from customers are excluded from revenue.

	Biotechnology		Life Sciences		Diagnostics		Total
For the Three-Month Period Ended June 27, 2025:
Geographical region:
North America(a)	$	612	$	762	$	1,064	$	2,438
Western Europe	708		394		405		1,507
Other developed markets(b)	82		118		94		294
High-growth markets(c)	448		503		746		1,697
Total	$	1,850	$	1,777	$	2,309	$	5,936
Revenue type:
Recurring	$	1,694	$	1,214	$	2,062	$	4,970
Nonrecurring	156		563		247		966
Total	$	1,850	$	1,777	$	2,309	$	5,936
For the Three-Month Period Ended June 28, 2024:
Geographical region:
North America(a)	$	607	$	785	$	1,042	$	2,434
Western Europe	567		374		380		1,321
Other developed markets(b)	81		116		95		292
High-growth markets(c)	458		495		743		1,696
Total	$	1,713	$	1,770	$	2,260	$	5,743
Revenue type:
Recurring	$	1,478	$	1,208	$	2,003	$	4,689
Nonrecurring	235		562		257		1,054
Total	$	1,713	$	1,770	$	2,260	$	5,743

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	Biotechnology		Life Sciences		Diagnostics		Total
For the Six-Month Period Ended June 27, 2025:
Geographical region:
North America(a)	$	1,155	$	1,483	$	2,382	$	5,020
Western Europe	1,274		772		805		2,851
Other developed markets(b)	146		241		185		572
High-growth markets(c)	887		961		1,386		3,234
Total	$	3,462	$	3,457	$	4,758	$	11,677
Revenue type:
Recurring	$	3,151	$	2,350	$	4,285	$	9,786
Nonrecurring	311		1,107		473		1,891
Total	$	3,462	$	3,457	$	4,758	$	11,677
For the Six-Month Period Ended June 28, 2024:
Geographical region:
North America(a)	$	1,121	$	1,566	$	2,379	$	5,066
Western Europe	1,113		746		786		2,645
Other developed markets(b)	160		241		194		595
High-growth markets(c)	843		962		1,428		3,233
Total	$	3,237	$	3,515	$	4,787	$	11,539
Revenue type:
Recurring	$	2,787	$	2,400	$	4,297	$	9,484
Nonrecurring	450		1,115		490		2,055
Total	$	3,237	$	3,515	$	4,787	$	11,539

NOTE 4. REVENUE

The following tables present the Company’s revenues disaggregated by geographical region and revenue type for the three and nine-month periods ended September 26, 2025 and September 27, 2024 ($ in millions). Sales taxes and other usage-based taxes collected from customers are excluded from revenue.


	Biotechnology		Life Sciences		Diagnostics		Total
For the Three-Month Period Ended September 26, 2025:
Geographical region:
North America(a)	$	624	$	728	$	1,228	$	2,580
Western Europe	587		392		417		1,396
Other developed markets(b)	89		130		97		316
High-growth markets(c)	498		542		721		1,761
Total	$	1,798	$	1,792	$	2,463	$	6,053

Revenue type:
Recurring	$	1,590	$	1,216	$	2,211	$	5,017
Nonrecurring	208		576		252		1,036
Total	$	1,798	$	1,792	$	2,463	$	6,053

For the Three-Month Period Ended September 27, 2024:
Geographical region:
North America(a)	$	503	$	796	$	1,157	$	2,456
Western Europe	587		365		368		1,320
Other developed markets(b)	78		120		101		299
High-growth markets(c)	485		501		737		1,723
Total	$	1,653	$	1,782	$	2,363	$	5,798

Revenue type:
Recurring	$	1,422	$	1,228	$	2,127	$	4,777
Nonrecurring	231		554		236		1,021
Total	$	1,653	$	1,782	$	2,363	$	5,798

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	Biotechnology		Life Sciences		Diagnostics		Total
For the Nine-Month Period Ended September 26, 2025:
Geographical region:
North America(a)	$	1,779	$	2,211	$	3,610	$	7,600
Western Europe	1,861		1,164		1,222		4,247
Other developed markets(b)	235		371		282		888
High-growth markets(c)	1,385		1,503		2,107		4,995
Total	$	5,260	$	5,249	$	7,221	$	17,730

Revenue type:
Recurring	$	4,741	$	3,566	$	6,496	$	14,803
Nonrecurring	519		1,683		725		2,927
Total	$	5,260	$	5,249	$	7,221	$	17,730

For the Nine-Month Period Ended September 27, 2024:
Geographical region:
North America(a)	$	1,624	$	2,362	$	3,536	$	7,522
Western Europe	1,700		1,111		1,154		3,965
Other developed markets(b)	238		361		295		894
High-growth markets(c)	1,328		1,463		2,165		4,956
Total	$	4,890	$	5,297	$	7,150	$	17,337

Revenue type:
Recurring	$	4,209	$	3,628	$	6,424	$	14,261
Nonrecurring	681		1,669		726		3,076
Total	$	4,890	$	5,297	$	7,150	$	17,337

(a) The Company defines North America as the United States and Canada.

(b) The Company defines other developed markets as all the markets of the world that are not North America, Western Europe or high-growth markets.

(c) The Company defines high-growth markets as developing markets of the world experiencing accelerated growth, over extended periods, in gross domestic product and infrastructure which include Eastern Europe, the Middle East, Africa, Latin America (including Mexico) and Asia (with the exception of Japan, Australia and New Zealand). The Company defines developed markets as all markets of the world that are not high-growth markets.

The Company’s products and services primarily consist of life sciences research, biopharmaceutical drug production and medical diagnostic products and services. The Company sells equipment to customers as well as consumables, software and services, some of which customers purchase on a recurring basis. Consumables sold for use with the equipment sold by the Company are typically critical to the use of the equipment and are typically used on a one-time or limited basis, requiring frequent replacement in the customer’s operating cycle. Examples of these consumables include reagents used in diagnostic tests, chromatography resins used for research and bioprocessing and filters used in filtration, separation and purification processes. Additionally, some of the Company’s consumables are used on a standalone basis, such as custom nucleic acids, genomics solutions, antibodies and immunoassays. The Company separates its goods and services between those typically sold to a customer on a recurring basis and those typically sold to a customer on a nonrecurring basis. Recurring revenue includes revenue from consumables (both used with Company equipment and used on a standalone basis), services and operating-type leases (“OTLs”). Nonrecurring revenue includes sales of equipment and sales-type leases (“STLs”). OTLs and STLs are included in the above revenue amounts. For the three-month periods ended ~~June~~September 2726, 2025 and ~~June~~September 2827, 2024, lease revenue was $~~117~~112 million and $9593 million, respectively. For the ~~six~~nine-month periods ended ~~June~~September 2726, 2025 and ~~June~~September 2827, 2024, lease revenue was $~~231~~343 million and $~~194~~287 million, respectively.

Remaining performance obligations related to Topic 606, Revenue from Contracts with Customers, represent the aggregate transaction price allocated to performance obligations with an original contract term greater than one year which are fully or partially unsatisfied at the end of the period. As of ~~June~~September 2726, 2025, the aggregate amount of the transaction price allocated to remaining performance obligations was approximately $4.9 billion. The Company expects to recognize revenue on approximately 46% of the remaining performance obligations over the next 12 months, 28% over the subsequent 12 months, and the remainder recognized thereafter.

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The timing of revenue recognition, billings and cash collections results in billed accounts receivable, unbilled receivables (“contract assets”) and deferred revenue, customer deposits and billings in excess of revenue recognized (“contract liabilities”) on the accompanying Consolidated Condensed Balance Sheets. Contract assets and liabilities are reported on a net basis (on a contract-by-contract basis) in the accompanying Consolidated Condensed Balance Sheets at the end of each reporting period.

The Company often receives cash payments from customers in advance of the Company’s performance, resulting in contract liabilities that are classified as either current or long-term in the accompanying Consolidated Condensed Balance Sheets based on the timing of when the Company expects to recognize revenue. As of ~~June~~September 2726, 2025 and December 31, 2024, contract liabilities were approximately $1.76 billion and $1.5 billion, respectively, and are included within accrued expenses and other liabilities and other long-term liabilities in the accompanying Consolidated Condensed Balance Sheets. The increase in the contract liability balance during the ~~six~~nine-month period ended ~~June~~September 2726, 2025 was primarily a result of cash payments received in advance of satisfying performance obligations, partially offset by amounts recognized as revenue. Revenue recognized during the ~~six~~nine-month periods ended ~~June~~September 2726, 2025 and ~~June~~September 2827, 2024 that was included in the contract liability balance on December 31, 2024 and December 31, 2023 was $~~769~~973 million and approximately $~~901~~1.1 ~~million~~billion, respectively.

NOTE 5. SEGMENT INFORMATION

The Company operates and reports its results in three separate business segments consisting of the Biotechnology, Life Sciences and Diagnostics segments. Operating profit represents total revenues less operating expenses, excluding nonoperating income and expense, interest and income taxes. The identifiable assets by segment are those used in each segment’s operations. Intersegment amounts are not significant and are eliminated to arrive at consolidated totals.

The chief operating decision maker (“CODM”) uses segment sales and operating profit to allocate resources (including employees and financial or capital resources), predominantly through the annual budget process, to evaluate and assess the performance of the segments and to evaluate the performance of certain employees for the determination of compensation. The CODM reviews forecast-to-actual variances in segment sales and operating profit on a monthly basis when making decisions about allocating capital and personnel to the segments.

The table below reconciles segment sales to segment operating profit with the expense categories presented reflecting the expenses that the Company has determined to be significant segment expenses. Significant segment expenses are the expense category details regularly provided to the CODM to allocate resources to the segments and to evaluate segment performance. Detailed segment data for the three and ~~six~~nine-month periods ended ~~June~~September 2726, 2025 and ~~June~~September 2827, 2024 is as follows ($ in millions):

	Biotechnology		Life Sciences		Diagnostics		Other(a)		Total
For the Three-Month Period Ended June 27, 2025:
For the Three-Month Period Ended September 26, 2025:
Sales	$	1,~~850~~798	$	1,~~777~~792	$	2,~~309~~463	$	—	$	56,~~936~~053
Less:
Depreciation	(38)		(4547)		(~~100~~101)		(23)		(~~185~~189)
Amortization of intangible assets	(~~228~~231)		(~~150~~154)		(48)		—		(~~426~~433)
Impairments(b)	—(86)		~~(432)~~—		—(15)		—		(~~432~~101)
Other segment expenses(c)	(1,~~053~~091)		(1,~~389~~369)		(1,~~607~~634)		(8482)		(4,~~133~~176)
Operating profit (loss)	$	531	$	(239)	$	554	$	(86)	$	760
Operating profit	$	352	$	222	$	665	$	(85)	$	1,154
For the Three-Month Period Ended June 28, 2024:
For the Three-Month Period Ended September 27, 2024:
Sales	$	1,~~713~~653	$	1,~~770~~782	$	2,~~260~~363	$	—	$	5,~~743~~798
Less:
Depreciation	(3536)		(4144)		(~~100~~95)		(2)		(~~178~~177)
Amortization of intangible assets	(~~214~~218)		(~~140~~147)		(4849)		—		(~~402~~414)
Other segment expenses(c)	(1,002)		(1,356)		(1,556)		(81)		(3,995)
Impairments(b)	—		(222)		—		—		(222)
Operating profit (loss)	$	462	$	233	$	556	$	(83)	$	1,168
Other segment expenses(c)	(1,009)		(1,334)		(1,604)		(80)		(4,027)
Operating profit (loss)	$	390	$	35	$	615	$	(82)	$	958

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	Biotechnology		Life Sciences		Diagnostics		Other(a)		Total
For the Six-Month Period Ended June 27, 2025:
For the Nine-Month Period Ended September 26, 2025:
Sales	$	35,~~462~~260	$	35,~~457~~249	$	47,~~758~~221	$	—	$	1117,~~677~~730
Less:
Depreciation	(72110)		(90137)		(~~200~~301)		(47)		(~~366~~555)
Amortization of intangible assets	(~~441~~672)		(~~299~~453)		(96144)		—		(~~836~~1,269)
Impairments(b)	(15101)		(432)		—(15)		—		(~~447~~548)
Other segment expenses(c)	(13,~~962~~053)		(24,~~674~~043)		(34,~~190~~824)		(~~168~~250)		(712,~~994~~170)
Operating profit (loss)	$	972	$	(38)	$	1,272	$	(172)	$	2,034
Operating profit	$	1,324	$	184	$	1,937	$	(257)	$	3,188
For the Six-Month Period Ended June 28, 2024:
For the Nine-Month Period Ended September 27, 2024:
Sales	$	34,~~237~~890	$	35,~~515~~297	$	47,~~787~~150	$	—	$	1117,~~539~~337
Less:
Depreciation	(77113)		(79123)		(~~197~~292)		(46)		(~~357~~534)
Amortization of intangible assets	(~~432~~650)		(~~281~~428)		(96145)		—		(~~809~~1,223)
Other segment expenses(c)	(1,941)		(2,687)		(3,108)		(157)		(7,893)
Impairments(b)	—		(222)		—		—		(222)
Operating profit (loss)	$	787	$	468	$	1,386	$	(161)	$	2,480
Other segment expenses(c)	(2,950)		(4,021)		(4,712)		(237)		(11,920)
Operating profit (loss)	$	1,177	$	503	$	2,001	$	(243)	$	3,438

(a) Other consists of unallocated corporate costs and other costs not considered part of management’s evaluation of reportable segment operating performance.

(b) For information on the impairments, refer to Note 8.

(c) Other segment expenses for each reportable segment include cost of sales, selling, general and administrative (“SG&A”) expenses and research and development (“R&D”) expenses, excluding in each case depreciation, amortization of intangible assets and impairments. Included within these categories of expenses are overhead expenses, stock compensation expense, restructuring charges and allocated corporate expenses.

The following table presents identifiable assets as of ~~June~~September 2726, 2025 and December 31, 2024 ($ in millions):

	June 27, 2025		December 31, 2024
	September 26, 2025		December 31, 2024
Identifiable assets:
Biotechnology	$	37,~~562~~296	$	34,605
Life Sciences	23,~~397~~179		23,211
Diagnostics	14,~~537~~653		14,204
Other	64,~~124~~769		5,522
Total	$	8179,~~620~~897	$	77,542

The following table presents capital expenditures for the three and ~~six~~nine-month periods ended ~~June~~September 2726, 2025 and ~~June~~September 2827, 2024 ($ in millions):

Three-Month Period Ended

~~Six~~Nine-Month Period Ended

June 27, 2025

June 28, 2024

June 27, 2025

June 28, 2024

September 26, 2025

September 27, 2024

September 26, 2025

September 27, 2024

Capital expenditures:

Biotechnology

8094

~~111~~117

~~161~~255

~~213~~330

Life Sciences

4140

5052

89129

~~110~~162

Diagnostics

~~125~~157

~~126~~129

~~240~~397

~~253~~382

Other

—

Total

~~248~~292

~~287~~298

~~493~~785

~~578~~876

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NOTE 6. INCOME TAXES

The following table summarizes the Company’s effective tax rate:

	Three-Month Period Ended				~~Six~~Nine-Month Period Ended
	June 27, 2025		June 28, 2024		June 27, 2025		June 28, 2024
	September 26, 2025		September 27, 2024		September 26, 2025		September 27, 2024
Effective tax rate	15.36	%	16.3	%	15.45	%	15.36	%

The Company operates globally, including in certain jurisdictions with lower tax rates than the United States (“U.S.”) federal statutory rate. Therefore, the impact of Danaher’s global operations and benefits from tax credits and incentives contributes to a lower effective tax rate compared to the U.S. federal statutory tax rate. For each period presented, the effective tax rate differs from the U.S. federal statutory rate of 21.0% principally due to the impact of the Company’s global operations, research tax credits, foreign-derived intangible income and aggregate net discrete benefits or charges.

For the three-month period ended ~~June~~September 2726, 2025, the effective tax rate was reduced by the tax effect from an intangible asset ~~impairment~~impairments in ajurisdictions ~~jurisdiction~~ with a higher statutory tax ~~rate~~rates than the Company’s effective tax rate, ~~partially~~which ~~offset~~reduced bythe ~~changes~~effective intax ~~uncertain~~rate ~~tax~~by ~~positions~~1.3%. ~~The~~There was no net ~~impact~~discrete ~~reduced~~tax charge in the ~~effective~~three-month ~~tax~~period, ~~rate~~as a valuation allowance recorded on certain foreign operating losses was offset by 1benefits from the remeasurement of deferred taxes in a jurisdiction which enacted a tax rate change.~~4%.~~

For the three-month period ended ~~June~~September 2827, 2024, ~~net~~the ~~discrete~~effective tax ~~benefits~~rate ofincluded ~~$9 million~~the tax effect from an intangible asset impairment in a jurisdiction with a higher statutory tax rate than the Company’s effective tax rate, which reduced the effective tax rate by 01.84%. There ~~and~~was ~~related~~no ~~primarily~~net todiscrete tax benefit in the three-month period, as excess tax benefits from stock-based compensation were offset by other discrete tax charges.

For the ~~six~~nine-month period ended ~~June~~September 2726, 2025, the effective tax rate was reduced by the tax effect from an intangible asset ~~impairment~~impairments in ajurisdictions ~~jurisdiction~~ with a higher statutory tax ~~rate~~rates than the Company’s effective tax rate, the remeasurement of deferred taxes in a jurisdiction which enacted a tax rate change and the release of reserves for uncertain tax positions due to the expiration of statutes of limitations, partially offset by a valuation allowance recorded on certain foreign operating losses and changes in uncertain tax positions. The net impact reduced the effective tax rate by 1.12%.

For the ~~six~~nine-month period ended ~~June~~September 2827, 2024, aggregate net discrete tax benefits ~~of $45 million~~ reduced the effective tax rate by 1.94% and related primarily to excess tax benefits from stock-based compensation, release of reserves for uncertain tax positions due to the expiration of statutes of ~~limitations~~limitation and changes in estimates associated with prior period uncertain tax positions. The effective tax rate for this period also included the tax effect from an intangible asset impairment, which reduced the effective tax rate by 0.5%.

In the fourth quarter of 2022, the U.S. Internal Revenue Service (“IRS”) proposed significant adjustments to the Company’s taxable income for the years 2016 through 2018 with respect to the deferral of tax on certain premium income related to the Company’s self-insurance programs. For income tax purposes, the recognition of premium income has been deferred in accordance with U.S. tax laws related to insurance. The proposed adjustments would have increased the Company’s taxable income over the 2016 through 2018 periods by approximately $2.5 billion. In the first quarter of 2023, the Company settled these proposed adjustments with the IRS, although the audit is still open with respect to other matters for the 2016 through 2018 period. The impact of the settlement with respect to the Company’s self-insurance policies was not material to the Company’s financial statements, including cash flows and the effective tax rate. As the settlement with the IRS was specific to the audit period, the settlement does not preclude the IRS from proposing similar adjustments to the Company’s self-insurance programs with respect to periods after 2018. Management believes the positions the Company has taken in its U.S. tax returns are in accordance with the relevant tax laws.

On July 4, 2025, the One Big Beautiful Bill Act (“OBBBA”) was enacted, which includes permanent extensions of most expiring Tax Cuts and Jobs Act provisions ~~and~~as well as international tax changes. The ~~Company~~application ~~is still evaluating the potential impacts~~ of the OBBBA; ~~however,~~to the Company ~~does~~did not ~~anticipate it will~~ have a material impact on ~~the~~its ~~Company’s~~ financial statements during the three-month period ended September 26, 2025.

For a description of the Company’s significant tax matters, reference is made to the financial statements as of and for the year ended December 31, 2024 and Note 7 thereto included in the Company’s 2024 Annual Report.

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NOTE 7. OTHER INCOME (EXPENSE), NET

The following sets forth the components of the Company’s other income (expense), net ($ in millions):

	Three-Month Period Ended				~~Six~~Nine-Month Period Ended
	June 27, 2025		June 28, 2024		June 27, 2025		June 28, 2024
	September 26, 2025		September 27, 2024		September 26, 2025		September 27, 2024
Other components of net periodic benefit costs	$	21	$	—(1)	$	45	$	1—
Investment gains (losses):
Realized investment gains (losses)	~~(6)~~—		—198		(72)		~~(39)~~159
Unrealized investment gains (losses)	(3815)		(5995)		(6277)		(57152)
Total investment gains (losses)	(4415)		~~(59)~~103		(~~134~~149)		~~(96)~~7
Gain on sale of product line	—		—		9		—
Total other income (expense), net	$	(4214)	$	~~(59)~~102	$	(~~121~~135)	$	~~(95)~~7

Other Components of Net Periodic Benefit Costs

The Company disaggregates the service cost component of net periodic benefit costs of noncontributory defined benefit pension plans and other postretirement employee benefit plans. The service cost component is presented in cost of goods sold and SG&A expenses. The other components of net periodic benefit costs are presented in other income (expense), net. These other components of net periodic benefit costs include the assumed rate of return on plan assets, partially offset by amortization of actuarial losses and interest.

Investment Gains (Losses)

For investments in equity securities without readily available fair values, the Company has elected the measurement alternative to record these investments at cost and to adjust for impairments and observable price changes with a same or similar security from the same issuer within net earnings (the “Fair Value Alternative”). Additionally, the Company is a limited partner in partnerships that invest primarily in early-stage companies. While the partnerships record these investments at fair value, the Company’s investments in the partnerships are accounted for under the equity method of accounting. The investment gains (losses) include realized and unrealized gains and losses related to changes in the fair value of the Company’s investments in equity securities and the Company’s equity in earnings of the partnerships that reflect the changes in fair value of the investments of the partnerships, and related management fees and operating expenses. In the third quarter of 2024, the Company sold a portion of its shares of an equity method investment and recorded a realized investment gain of $180 million ($135 million after-tax) for the three and nine-month periods ended September 27, 2024.

Gain on Sale of Product Line

During the ~~six~~nine-month period ended ~~June~~September 2726, 2025, the Company divested a product line for a cash purchase price of $9 million and recognized a pretax gain on sale of $9 million ($7 million after-tax). The divested product line generated revenues of approximately $50 million in the Diagnostics segment in 2024. The divestiture of this product line did not represent a strategic shift with a major effect on the Company’s operations and financial results and therefore is not reported as a discontinued operation.

NOTE 8. GOODWILL AND OTHER INTANGIBLE ASSETS

The following is a rollforward of the Company’s goodwill ($ in millions):

Balance, December 31, 2024	$	40,497
Adjustments due to finalization of purchase price allocations	39
Foreign currency translation and other	2,~~491~~442
Balance, June 27, 2025	$	42,991
Balance, September 26, 2025	$	42,948

The carrying value of goodwill by segment is summarized as follows ($ in millions):

	June 27, 2025		December 31, 2024
	September 26, 2025		December 31, 2024
Biotechnology	$	23,~~139~~145	$	21,437
Life Sciences	12,~~881~~837		12,305
Diagnostics	6,~~971~~966		6,755
Total	$	42,~~991~~948	$	40,497

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The Company reviews identified intangible assets for impairment whenever events or changes in circumstances indicate that the related carrying amounts may not be recoverable.

During the ~~second~~third quarter of ~~2025~~2024, the Company ~~decided~~concluded tothat ~~reorganize~~it ~~and~~had ~~integrate~~an ~~certain~~impairment ~~businesses~~indicator for an indefinite-lived trade name within ~~its~~the genomics consumable business included in the Life Sciences segment, toprimarily ~~better~~as ~~serve~~a ~~the~~result ~~Company’s~~of ~~customers~~softness in ~~new~~the genomics market, ~~segments~~including ~~and~~but tonot ~~respond~~limited to ~~current~~the ~~market~~discontinuation ~~conditions. As~~of acertain ~~result~~drug ofdevelopment ~~these~~programs ~~plans,~~announced in the ~~Company~~third ~~concluded~~quarter ~~that~~of an2024, ~~indefinite-lived~~weaker ~~trade~~demand ~~name~~at ~~within~~some of the ~~genomics~~business’s ~~consumables~~larger ~~business~~customers ~~was~~as nowell ~~longer~~as ~~considered~~reduced demand due to bethe ~~indefinite-lived,~~reprioritization ~~resulting~~of indrug andevelopment ~~impairment~~programs ~~indicator~~at other customers. The Company engaged a third-party valuation specialist to assist in the valuation of the trade name using a relief from royalty method of valuation. The significant assumptions in the relief from royalty method ~~include~~included, but were not limited to, revenue, revenue growth rates, planned use of the trade name, royalty rates and discount rates. The Company recorded a noncash impairment charge of $~~432~~222 million pretax ($~~328~~169 million after-tax) related to the trade name for the three and ~~six~~nine-~~months~~month periods ended ~~June~~ September 27, ~~2025~~2024, which is included in selling, general and administrative expenses in the accompanying Consolidated Condensed Statements of Earnings. The amount of the impairment was primarily attributable to the conclusion that the trade name was no longer indefinite-lived, as well as, by current lower levels of demand in the genomics market, including at emerging biotechnology customers and at two large customers. After recognition of the impairment, the remaining net book value of the trade name was $76 million as of June 27, 2025 and will be amortized over the asset’s remaining useful life of eight years. The Company continues to monitor for any changes to the business performance or key assumptions.

InDuring ~~connection~~the ~~with~~second quarter of 2025, the ~~trade~~Company ~~name~~decided ~~impairment~~to reorganize and integrate certain businesses within its Life Sciences segment to better serve the Company’s customers in new market segments and to respond to current market conditions. As a result of these plans, the Company ~~also~~concluded ~~tested~~that the ~~related~~same ~~long~~indefinite-lived ~~asset~~trade ~~group~~name ~~and~~within the ~~related~~genomics ~~reporting~~consumables ~~unit~~business ~~goodwill~~was ~~for~~no longer considered to be indefinite-lived, resulting in an impairment asindicator. The Company engaged a third-party valuation specialist to assist in the valuation of ~~June~~the 27trade name using a relief from royalty method of valuation. The Company recorded a noncash impairment charge of $432 million pretax ($328 million after-tax) related to the trade name for the nine-month period ended September 26, 2025, which is included in selling, general and administrative expenses in ~~both~~the ~~cases~~accompanying Consolidated Condensed Statements of Earnings. The amount of the ~~Company~~impairment ~~identified~~was primarily attributable to the conclusion that the trade name was no longer indefinite-lived, as well as current lower levels of demand in the genomics market, including at emerging biotechnology customers and at two large customers. After recognition of the impairment in the second quarter of 2025, the remaining net book value of the trade name was $76 million and will be amortized over the asset’s remaining useful life of eight years. The Company continues to monitor for any changes to the business performance or key assumptions.

In connection with both trade name impairments mentioned above, the Company also tested the related long-lived asset group and the related reporting unit goodwill for impairment, and in each case the Company identified no impairment.

During the third quarter of 2025, the Company identified impairment triggers for certain technology assets, a trade name and other intangible assets in the Biotechnology and Diagnostics segments. In the three and nine-month periods ended September 26, 2025, the Company recorded impairment charges of $101 million related to these long-lived assets, which is included in selling, general and administrative expenses in the accompanying Consolidated Condensed Statements of Earnings. Additionally, during the nine-month period ended September 26, 2025, the Company recorded a $15 million impairment related to a facility in the Biotechnology segment.

The reorganization of the Life Sciences segment resulted in a change to the businesses included in two of the Company’s five reporting units for goodwill beginning at the start of the third quarter of 2025. The Company used the relative fair value method to reallocate goodwill between the impacted reporting units within the Life Sciences segment. The Company performed the quantitative goodwill impairment analysis immediately prior to and following the change in the reporting units. As of the date of the impairment tests, the carrying value of the goodwill included in each individual reporting unit ranged from approximately $1.2 billion to $23.1 billion for both the previous reporting units and for the current reporting units (after the changes within Life Sciences). No impairments of goodwill were identified in either of the impairment evaluations before or immediately after the change in reporting units. The factors used by management in its impairment analysis are inherently subject to uncertainty. If actual results are not consistent with management’s estimates and assumptions, goodwill and other intangible assets may not be recoverable and a charge would need to be taken against net earnings.

During the six-month period ended June 27, 2025, the Company recorded a $15 million impairment related to a facility in the Biotechnology segment.

The Company will continue to review goodwill and other intangible assets for impairment when events or changes in circumstances, including evolving market conditions and regulatory environment, indicate related carrying amounts may not be recoverable.

NOTE 9. FAIR VALUE MEASUREMENTS

Accounting standards define fair value based on an exit price model, establish a framework for measuring fair value where the Company’s assets and liabilities are required to be carried at fair value and provide for certain disclosures related to the valuation methods used within a valuation hierarchy as established within the accounting standards. This hierarchy prioritizes the inputs into three broad levels as follows. Level 1 inputs are quoted prices (unadjusted) in active markets for identical assets or liabilities. Level 2 inputs are quoted prices for similar assets and liabilities in active markets, quoted prices for identical or similar assets in markets that are not active, or other observable characteristics for the asset or liability, including interest rates, yield curves and credit risks, or inputs that are derived principally from, or corroborated by, observable market data through correlation. Level 3 inputs are unobservable inputs based on the Company’s assumptions. A financial asset or liability’s classification within the hierarchy is determined based on the lowest level input that is significant to the fair value measurement in its entirety.

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observable market data through correlation. Level 3 inputs are unobservable inputs based on the Company’s assumptions. A financial asset or liability’s classification within the hierarchy is determined based on the lowest level input that is significant to the fair value measurement in its entirety.

A summary of financial assets that are measured at fair value on a recurring basis were as follows ($ in millions):

	Balance				Quoted Prices in Active Market (Level 1)				Significant Other Observable Inputs (Level 2)				Significant Unobservable Inputs (Level 3)
	June 27, 2025		December 31, 2024		June 27, 2025		December 31, 2024		June 27, 2025		December 31, 2024		June 27, 2025		December 31, 2024
	September 26, 2025		December 31, 2024		September 26, 2025		December 31, 2024		September 26, 2025		December 31, 2024		September 26, 2025		December 31, 2024
Assets:
Investment in equity securities	$	~~195~~194	$	218	$	—	$	3	$	—	$	—	$	—	$	—
Cross-currency swap derivative contracts	84129		415		—		—		84129		415		—		—
Liabilities:
Cross-currency swap derivative contracts	8644		—		—		—		8644		—		—		—

The Company’s investments in equity securities consist of investments in publicly traded equity securities and investments in non-marketable equity securities. The publicly traded securities are classified as Level 1 in the fair value hierarchy as they are measured based on quotes in active markets. For the non-marketable equity securities, the Company estimates the fair value of the investments using the Fair Value Alternative. The Company’s investments in these equity securities are not classified in the fair value hierarchy due to the use of these measurement methods. Additionally, the Company is a limited partner in partnerships that invest primarily in early-stage companies. While the partnerships record these investments at fair value, the Company’s investments in the partnerships are accounted for under the equity method of accounting and are not subject to the fair value measurement disclosures noted above. As of both ~~June~~September 2726, 2025 and December 31, 2024, the Company’s equity method investments included investments in partnerships with a carrying value of approximately $1.4 billion. Refer to Note 7 for additional information on gains and losses on the Company’s investments including investments in the partnerships.

The cross-currency swap derivative contracts are classified as Level 2 in the fair value hierarchy as they are measured using the income approach with the relevant interest rates and current currency exchange rates and forward curves as inputs. Refer to Note 11 for additional information.

Fair Value of Other Financial Instruments

The carrying amounts and fair values of the Company’s other financial instruments were as follows ($ in millions):

June 27, 2025

December 31, 2024

September 26, 2025

December 31, 2024

Carrying Amount

Fair Value

Carrying Amount

Fair Value

Debt obligations:

Notes payable and current portion of long-term debt

~~502~~23

~~500~~23

505

502

Long-term debt

16,~~853~~833

14,~~373~~470

15,500

13,109

As of ~~June~~September 2726, 2025 and December 31, 2024, short and long-term borrowings were categorized as Level 1. The fair value of long-term borrowings was based on quoted market prices. The difference between the fair value and the carrying amounts of long-term borrowings is attributable to changes in market interest rates and/or the Company’s credit ratings subsequent to the incurrence of the borrowing. The fair values of borrowings with original maturities of one year or less, as well as cash and cash equivalents, trade accounts receivable, net and trade accounts payable generally approximate their carrying amounts due to the short-term maturities of these instruments.

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NOTE 10. FINANCING

As of September 26, 2025, the Company was in compliance with all of its debt covenants. The components of the Company’s debt were as follows ($ in millions):

	Outstanding Amount
Description and Aggregate Principal Amount	~~June~~September 2726, 2025		December 31, 2024
Euro-denominated commercial paper (€932 million and €931 million, respectively)(a)	$	1,091	$	965
Euro-denominated commercial paper (€933 million and €931 million, respectively)(a)	$	1,092	$	965
3.35% senior unsecured notes due 9/15/2025 ($500 million) (the “2025 U.S. Notes”)(b)	~~500~~—		500
0.2% senior unsecured notes due 3/18/2026 (€1.3 billion) (the “2026 Biopharma Euronotes”)(c)	1,~~463~~462		1,293
2.1% senior unsecured notes due 9/30/2026 (€800 million) (the “2026 Euronotes”)(b)	936		828
0.3% senior unsecured notes due 5/11/2027 (¥30.8 billion) (the “2027 Yen Notes”)(d)	~~213~~206		195
1.2% senior unsecured notes due 6/30/2027 (€600 million) (the “2027 Euronotes”)(e)	701		620
0.45% senior unsecured notes due 3/18/2028 (€1.3 billion) (the “2028 Biopharma Euronotes”)(c)	1,460		1,291
1.125% senior unsecured bonds due 12/08/2028 (CHF 210 million) (the “2028 CHF Bonds”)(f)	~~264~~265		233
2.6% senior unsecured notes due 11/15/2029 ($800 million) (the “2029 Biopharma Notes”)(c)	~~797~~798		797
2.5% senior unsecured notes due 3/30/2030 (€800 million) (the “2030 Euronotes”)(b)	~~937~~936		829
0.75% senior unsecured notes due 9/18/2031 (€1.8 billion) (the “2031 Biopharma Euronotes”)(c)	2,~~042~~041		1,805
0.65% senior unsecured notes due 5/11/2032 (¥53.2 billion) (the “2032 Yen Notes”)(d)	~~367~~355		337
1.35% senior unsecured notes due 9/18/2039 (€1.3 billion) (the “2039 Biopharma Euronotes”)(c)	1,~~451~~450		1,282
3.25% senior unsecured notes due 11/15/2039 ($900 million) (the “2039 Biopharma Notes”)(c)	892		892
4.375% senior unsecured notes due 9/15/2045 ($500 million) (the “2045 U.S. Notes”)(b)	500		499
1.8% senior unsecured notes due 9/18/2049 (€750 million) (the “2049 Biopharma Euronotes”)(c)	870		769
3.4% senior unsecured notes due 11/15/2049 ($900 million) (the “2049 Biopharma Notes”)(c)	~~890~~891		890
2.6% senior unsecured notes due 10/01/2050 ($1.0 billion) (the “2050 U.S. Notes”)(b)	982		982
2.8% senior unsecured notes due 12/10/2051 ($1.0 billion) (the “2051 U.S. Notes”)(b)	985		985
Other	1434		13
Total debt	1716,~~355~~856		16,005
Less: currently payable	(~~502~~23)		(505)
Long-term debt	$	16,~~853~~833	$	15,500

(a) Issued by Danaher Corporation or DH Europe Finance II S.a.r.l. (“Danaher International II”).

(b) Issued by Danaher Corporation.

(d) Issued by DH Japan Finance S.Aa.r.l. (“Danaher Japan”).

(e) Issued by DH Europe Finance S.Aa.r.l. (“Danaher International”).

(f) Issued by DH Switzerland Finance S.Aa.r.l. (“Danaher Switzerland”).

Debt discounts, premiums and debt issuance costs totaled $9188 million and $96 million as of ~~June~~September 2726, 2025 and December 31, 2024, respectively, and have been netted against the aggregate principal amounts of the related debt in the components of debt table above. For additional details regarding the Company’s debt financing, refer to Note 13 of the Company’s financial statements as of and for the year ended December 31, 2024 included in the Company’s 2024 Annual Report.

16The Company has historically satisfied short-term liquidity needs that are not met through operating cash flow and available cash primarily through issuances of commercial paper under its U.S. dollar and euro-denominated commercial paper programs. The Company’s $5.0 billion unsecured, multi-year revolving credit facility with a syndicate of banks that expires on August 11, 2028 (the “Credit Facility”) is available for direct borrowings and provides credit support for the commercial paper programs. For a description of the Credit Facility, refer to the Company’s 2024 Annual Report. As of September 26, 2025, the Company has classified approximately $2.6 billion of its borrowings outstanding under the euro-denominated commercial paper programs and the 2026 Biopharma Euronotes as long-term debt in the accompanying Consolidated Condensed Balance Sheet (even though such borrowings are scheduled to mature within one year of September 26, 2025) as the Company had the intent and ability, as supported by availability under the Credit Facility, to refinance these borrowings for at least one year from the balance sheet date.

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~~The~~As ~~Company~~of ~~has~~September 26, ~~historically~~2025, ~~satisfied~~borrowings ~~short-term~~outstanding ~~liquidity needs that are not met through operating cash flow and available cash primarily through issuances of commercial paper~~ under ~~its~~the ~~U.S.~~Company’s ~~dollar and~~ euro-denominated commercial paper ~~programs. The~~program ~~Company’s~~had ~~$5.0 billion~~a ~~unsecured,~~weighted ~~multi-year~~average ~~revolving~~annual ~~credit~~interest ~~facility~~rate ~~with a syndicate~~ of ~~banks~~2.2% ~~that expires on August 11, 2028 (the “Credit Facility”), is available for direct borrowings~~ and ~~provides~~a ~~credit~~weighted ~~support~~average ~~for~~remaining ~~the~~maturity ~~commercial paper programs. For a description~~ of ~~the~~approximately ~~Credit~~27 ~~Facility, refer to the Company’s 2024 Annual Report~~days. AsThere ofwere ~~June 27,~~no ~~2025, the Company has classified approximately $2.6 billion of its~~ borrowings outstanding under the ~~euro~~U.S. dollar-denominated commercial paper ~~programs~~program ~~and the 2026 Biopharma Euronotes~~ as ~~long-term debt in the accompanying Consolidated Condensed Balance Sheets (even though such borrowings are scheduled to mature within one year~~ of ~~June~~September 2726, 2025~~) as the Company had the intent and ability, as supported by availability under the Credit Facility, to refinance these borrowings for at least one year from the balance sheet date~~.

~~As of June 27, 2025, borrowings outstanding under the Company’s euro~~Long-~~denominated~~Term ~~commercial~~Debt paper program had a weighted average annual interest rate of 2.3% and a weighted average remaining maturity of approximately 41 days. There were no borrowings outstanding under the U.S. dollar-denominated commercial paper program as of June 27, 2025.Repayments

On September 15, 2025, the Company repaid the $500 million aggregate principal amount of the 2025 U.S. Notes upon their maturity using available cash and proceeds from the issuance of commercial paper.

2025 Debt Issuances

On October 10, 2025, Danaher Switzerland, a wholly-owned finance subsidiary of the Company, completed an underwritten offering of Swiss franc-denominated bonds due 2027, 2029, 2033, 2037 and 2045 (collectively the “Swiss Bonds”). The following summarizes the key terms of the offering in aggregate:

Aggregate Principal Amount (in millions)

Stated Annual Interest Rate

Maturity Date

Interest Payment Dates (in arrears)

2027 CHF Bonds

CHF 250

0.4773

April 9, 2027

April 9

2029 CHF Bonds

CHF 325

0.8875

October 10, 2029

October 10

2033 CHF Bonds

CHF 325

1.265

October 10, 2033

October 10

2037 CHF Bonds

CHF 225

1.6249

October 9, 2037

October 9

2045 CHF Bonds

CHF 125

1.94

October 10, 2045

October 10

Total Swiss Bonds

CHF 1,250

The Company received net proceeds from the issuance, after underwriting discounts and commissions and offering expenses, of approximately CHF 1.2 billion (approximately $1.6 billion based on currency exchange rates as of the date of the pricing of the Swiss Bonds). The proceeds from the issuance have been and will be used for general corporate purposes, which may include share repurchases, repayment of debt, acquisitions, capital expenditures or other investing activities.

Guarantors of Debt

Danaher Corporation has guaranteed long-term debt and commercial paper issued by certain of its wholly-owned finance subsidiaries: Danaher International, Danaher International II, Danaher Switzerland and Danaher Japan. All of the outstanding and future securities issued by each of these entities are or will be fully and unconditionally guaranteed by Danaher Corporation and these guarantees rank on parity with Danaher Corporation’s unsecured and unsubordinated indebtedness.

NOTE 11. HEDGING TRANSACTIONS AND DERIVATIVE FINANCIAL INSTRUMENTS

The Company uses cross-currency swap derivative contracts to partially hedge its net investments in non-U.S. operations against adverse movements in exchange rates between the U.S. dollar and the Danish kroner, Japanese yen, euro and Swiss franc. These contracts are agreements to exchange fixed-rate payments in one currency for fixed-rate payments in another currency and effectively convert U.S. dollar-denominated bonds to obligations denominated in the hedged currency. These contracts also reduce the interest rate from the stated interest rates on the U.S. dollar-denominated debt to the interest rates of the swaps. The changes in the spot rate of these instruments are recorded in accumulated other comprehensive income (loss) (“OCI”) in stockholders’ equity, partially offsetting the foreign currency translation adjustment of the Company’s related net investment that is also recorded in accumulated OCI. The interest income or expense from these swaps are recorded in interest expense in the accompanying Consolidated Condensed Statements of Earnings consistent with the classification of interest expense attributable to the underlying debt. These instruments mature on dates ranging from ~~September~~October 2025 to December 2031.

The Company also uses cross-currency swap derivative contracts to hedge U.S. dollar-denominated long-term debt issuances in a foreign subsidiary whose functional currency is the euro against adverse movements in exchange rates. These contracts effectively convert these U.S. dollar-denominated bonds to obligations denominated in euro. The changes in the fair value of these instruments are recorded in accumulated OCI and are subsequently reclassified to net earnings to offset the remeasurement of the hedged debt that is also recorded in net earnings. The interest income or expense from these swaps are recorded in interest expense in the accompanying Consolidated Condensed Statements of Earnings consistent with the classification of interest expense attributable to the underlying debt. These instruments mature on dates ranging from November 2029 to November 2049.

The Company has also issued foreign currency denominated long-term debt as partial hedges of its net investments in foreign operations against adverse movements in exchange rates between the U.S. dollar and the euro, Japanese yen and Swiss franc. These debt issuances are designated and qualify as nonderivative hedging instruments. Accordingly, the foreign currency translation of these debt instruments is recorded in accumulated OCI, offsetting the foreign currency translation adjustment of the Company’s related net investment that is also recorded in accumulated OCI. These instruments mature on dates ranging from July 2025 to May 2032.

The Company used interest rate swap agreements to hedge the variability in cash flows due to changes in benchmark interest rates related to a portion of the debt the Company issued. These contracts effectively fixed the interest rate for a portion of the Company’s debt equal to the notional amount of the swaps to the rate specified in the interest rate swap agreements and were settled in November 2019 and December 2021. The changes in the fair value of these instruments were recorded in accumulated OCI prior to the issuance of the debt and are subsequently being reclassified to interest expense over the life of the related debt.

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The following table summarizes the notional values as of June 27, 2025 and June 28, 2024 and pretax impact of changes in the fair values of instruments designated as net investment hedges and cash flow hedges in accumulated OCI for the three and six-month periods ended June 27, 2025 and June 28, 2024 ($ in millions):

	Original Notional Amount		Notional Amount Outstanding		Gain (Loss) Recognized in OCI		Amounts Reclassified from OCI
For the Three-Month Period Ended June 27, 2025:
Net investment hedges:
Cross-currency contracts	$	3,875	$	3,000	$	(202)	$	—
Foreign currency denominated debt	4,509		4,509		(290)		—
Cash flow hedges:
Cross-currency contracts	4,000		2,600		(200)		213
Interest rate swaps	1,600		—		—		—
Total	$	13,984	$	10,109	$	(692)	$	213
For the Three-Month Period Ended June 28, 2024:
Net investment hedges:
Cross-currency contracts	$	3,875	$	3,000	$	52	$	—
Foreign currency denominated debt	3,109		3,109		48		—
Cash flow hedges:
Cross-currency contracts	4,000		3,300		55		(25)
Interest rate swaps	1,600		—		—		1
Total	$	12,584	$	9,409	$	155	$	(24)
For the Six-Month Period Ended June 27, 2025:
Net investment hedges:
Cross-currency contracts	$	3,875	$	3,000	$	(256)	$	—
Foreign currency denominated debt	4,509		4,509		(426)		—
Cash flow hedges:
Cross-currency contracts	4,000		2,600		(161)		329
Interest rate swaps	1,600		—		—		1
Total	$	13,984	$	10,109	$	(843)	$	330
For the Six-Month Period Ended June 28, 2024:
Net investment hedges:
Cross-currency contracts	$	3,875	$	3,000	$	107	$	—
Foreign currency denominated debt	3,109		3,109		182		—
Cash flow hedges:
Cross-currency contracts	4,000		3,300		78		(99)
Interest rate swaps	1,600		—		—		2
Total	$	12,584	$	9,409	$	367	$	(97)

Gains or losses related to the net investment hedges are classified as foreign currency translation adjustments in the schedule of changes in OCI in Note 12, as these items are attributable to the Company’s hedges of its net investment in foreign operations. Gains or losses related to the cash flow hedges are classified as cash flow hedge adjustments in the schedule of changes in OCI in Note 12. The amount reclassified from OCI for the cross-currency swap derivative contracts that are cash flow hedges of the Company’s U.S. dollar-denominated debt was equal to the remeasurement amount recorded in the three and six-month periods on the hedged debt.

The Company did not reclassify any other deferred gains or losses related to net investment hedges or cash flow hedges from accumulated OCI to earnings during the three and six-month periods ended June 27, 2025 and June 28, 2024. In addition, the Company did not have any ineffectiveness related to net investment hedges or cash flow hedges during the three and six-month periods ended June 27, 2025 and June 28, 2024. Should any ineffectiveness arise, any ineffective

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~~portions~~and ofSwiss ~~the~~franc. These ~~hedges~~debt ~~would~~issuances beare ~~reclassified~~designated ~~from~~and ~~accumulated~~qualify ~~OCI~~as ~~into~~nonderivative ~~earnings~~hedging ~~during the period of change~~instruments. ~~The~~Accordingly, ~~cash inflows and outflows associated with~~ the ~~Company’s~~foreign ~~derivative~~currency ~~contracts~~translation ~~designated~~of asthese ~~net~~debt ~~investment~~instruments ~~hedges~~is ~~are~~recorded ~~classified~~ in ~~all~~accumulated ~~other~~OCI, ~~investing~~offsetting ~~activities in~~ the ~~accompanying~~foreign ~~Consolidated~~currency ~~Condensed~~translation ~~Statements~~adjustment of ~~Cash Flows. The cash inflows and outflows associated with~~ the Company’s ~~derivative~~related ~~contracts~~net ~~designated~~investment asthat ~~cash~~is ~~flow~~also ~~hedges~~recorded ~~are classified~~ in ~~cash~~accumulated ~~flows~~OCI. These ~~from~~instruments ~~operating~~mature ~~activities~~on indates ~~the~~ranging ~~accompanying~~from ~~Consolidated~~September ~~Condensed~~2025 ~~Statements~~to ofMay ~~Cash Flows~~2032.

The following table summarizes the notional values as of September 26, 2025 and September 27, 2024 and pretax impact of changes in the fair values of instruments designated as net investment hedges and cash flow hedges in accumulated OCI for the three and nine-month periods ended September 26, 2025 and September 27, 2024 ($ in millions):


	Original Notional Amount		Notional Amount Outstanding		Gain (Loss) Recognized in OCI		Amounts Reclassified from OCI
For the Three-Month Period Ended September 26, 2025:
Net investment hedges:
Cross-currency contracts	$	3,875	$	2,500	$	22	$	—
Foreign currency denominated debt	4,490		4,490		21		—
Cash flow hedges:
Cross-currency contracts	4,000		2,600		49		(1)
Interest rate swaps	1,600		—		—		1
Total	$	13,965	$	9,590	$	92	$	—

For the Three-Month Period Ended September 27, 2024:
Net investment hedges:
Cross-currency contracts	$	3,875	$	3,000	$	(97)	$	—
Foreign currency denominated debt	3,294		3,294		(185)		—
Cash flow hedges:
Cross-currency contracts	4,000		3,300		(77)		140
Interest rate swaps	1,600		—		—		—
Total	$	12,769	$	9,594	$	(359)	$	140

For the Nine-Month Period Ended September 26, 2025:
Net investment hedges:
Cross-currency contracts	$	3,875	$	2,500	$	(234)	$	—
Foreign currency denominated debt	4,490		4,490		(405)		—
Cash flow hedges:
Cross-currency contracts	4,000		2,600		(112)		328
Interest rate swaps	1,600		—		—		2
Total	$	13,965	$	9,590	$	(751)	$	330

For the Nine-Month Period Ended September 27, 2024:
Net investment hedges:
Cross-currency contracts	$	3,875	$	3,000	$	10	$	—
Foreign currency denominated debt	3,294		3,294		(3)		—
Cash flow hedges:
Cross-currency contracts	4,000		3,300		1		41
Interest rate swaps	1,600		—		—		2
Total	$	12,769	$	9,594	$	8	$	43

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Gains or losses related to the net investment hedges are classified as foreign currency translation adjustments in the schedule of changes in OCI in Note 13, as these items are attributable to the Company’s hedges of its net investment in foreign operations. Gains or losses related to the cash flow hedges are classified as cash flow hedge adjustments in the schedule of changes in OCI in Note 13. The amount reclassified from OCI for the cross-currency swap derivative contracts that are cash flow hedges of the Company’s U.S. dollar-denominated debt was equal to the remeasurement amount recorded in the three and nine-month periods on the hedged debt.

The Company did not reclassify any other deferred gains or losses related to net investment hedges or cash flow hedges from accumulated OCI to earnings during the three and nine-month periods ended September 26, 2025 and September 27, 2024. In addition, the Company did not have any ineffectiveness related to net investment hedges or cash flow hedges during the three and nine-month periods ended September 26, 2025 and September 27, 2024. Should any ineffectiveness arise, any ineffective portions of the hedges would be reclassified from accumulated OCI into earnings during the period of change. The cash inflows and outflows associated with the Company’s derivative contracts designated as net investment hedges are classified in all other investing activities in the accompanying Consolidated Condensed Statements of Cash Flows. The cash inflows and outflows associated with the Company’s derivative contracts designated as cash flow hedges are classified in cash flows from operating activities in the accompanying Consolidated Condensed Statements of Cash Flows.

The Company’s derivative instruments, as well as its nonderivative debt instruments designated and qualifying as net investment hedges, were classified in the Company’s Consolidated Condensed Balance Sheets as follows ($ in millions):

	June 27, 2025		December 31, 2024
	September 26, 2025		December 31, 2024
Derivative assets:
Other long-term assets	$	84129	$	415
Derivative liabilities:
Accrued expenses and other liabilities	8644		—
Nonderivative hedging instruments:
Long-term debt	4,~~509~~490		3,042

Amounts related to the Company’s derivatives expected to be reclassified from accumulated OCI to net earnings during the next 12 months, if interest rates and foreign exchange rates remain unchanged, were not significant.

NOTE 12. ~~STOCKHOLDERS'~~COMMITMENTS ~~EQUITY~~ AND ~~STOCK-BASED COMPENSATION~~CONTINGENCIES

~~Stockholders~~On July 17, 2023, a putative securities class action was filed in the United States District Court for the District of Columbia, captioned Hawkins v. Danaher Corporation et al., Case No. 1:23-cv-02055 (“Hawkins Action”). The complaint was amended on December 29, 2023 and names the Company and certain of its current or former officers. The complaint purports to assert claims under Section 10(b) of the Securities Exchange Act of 1934, as amended (the “1934 Act”), SEC Rule 10b-5, and Section 20(a) of the 1934 Act, on behalf of persons and entities who acquired our securities between January 27, 2022 and October 23, 2023 (the “Class Period”). Plaintiffs allege that, during the Class Period, defendants made material misrepresentations or omissions regarding, among other things, the Company’s ~~Equity~~anticipated revenues for its bioprocessing business that artificially inflated the Company’s stock price. Plaintiffs seek, among other things, damages in an unspecified amount, as well as fees and costs. The Company moved to dismiss the amended complaint on February 27, 2024, and on August 4, 2025, the court granted in part and denied in part the Company’s motion to dismiss.

OnSince ~~July~~January 162024, ~~2013,~~putative ~~the~~shareholder ~~Company’s~~derivative ~~Board~~cases ofhave ~~Directors~~been ~~approved~~filed ain ~~repurchase program (~~the ~~“Completed~~United ~~Repurchase~~States ~~Program”)~~District ~~authorizing~~Court for the ~~repurchase~~District of upDelaware. Those tocases 20have ~~million~~been ~~shares~~consolidated ofand ~~the~~are ~~Company’s~~captioned ~~common~~In ~~stock~~re ~~from~~Danaher ~~time~~Corporation toDerivative ~~time~~Litigation, onNo. 1:24-cv-00091-GBW (the ~~open~~“Derivative ~~market~~Action”). The orDerivative inAction ~~privately~~names ~~negotiated~~the ~~transactions. During~~Company ~~the~~as ~~year~~a ~~ended~~nominal ~~December~~defendant ~~31,~~and ~~2024,~~purports ~~the~~to ~~Company~~bring ~~repurchased~~claims ~~approximately~~on 20behalf ~~million~~of ~~shares~~the Company against certain of the Company’s ~~common~~current ~~stock~~and ~~under~~former ~~the~~directors ~~Completed~~and ~~Repurchase~~officers ~~Program~~for ~~including~~alleged violations of the ~~repurchase~~federal securities laws and breaches of ~~approximately~~their ~~17.4~~fiduciary ~~million~~duties, ~~shares~~among ofother claims, in relation to substantially the ~~Company’s~~same ~~common~~factual ~~stock~~allegations ~~for~~as ~~approximately~~those $4made in the Hawkins Action.6 These ~~billion,~~actions ~~inclusive~~seek ofto ~~excise~~recover ~~taxes,~~unspecified ~~during~~damages ~~the~~and ~~second~~other ~~quarter~~relief ofon ~~2024~~the Company’s behalf. AsProceedings ofin ~~December~~the ~~31,~~Derivative ~~2024~~Action nohave ~~shares~~been ~~remained~~stayed ~~available~~during ~~for~~the ~~repurchase~~pendency ~~pursuant~~of to the ~~Completed~~Hawkins ~~Repurchase Program~~Action.

InThe ~~the~~outcomes ~~second quarter~~ of ~~2025~~these ~~the~~legal ~~Company~~proceedings ~~paid~~remain ~~$56 million~~uncertain inand ~~excise taxes related to~~ the ~~2024~~Company ~~share repurchases. Cash paid for excise taxes on share repurchases~~ is ~~included~~unable into ~~all~~reasonably ~~other~~estimate ~~financing activities in~~ the ~~accompanying~~possible ~~Consolidated~~loss ~~Condensed~~or ~~Statement~~range of ~~Cash~~loss, ~~Flows~~if any.

OnFor ~~July~~further ~~22,~~discussion ~~2024,~~of the Company’s ~~Board~~litigation ofand ~~Directors~~contingencies, ~~approved~~refer ~~a repurchase program (the “Repurchase Program”) authorizing the repurchase of up~~ to 20Note ~~million~~17 ~~shares~~ of the Company’s ~~common~~financial ~~stock~~statements ~~from~~as ~~time~~of toand ~~time~~for on the ~~open market or in privately negotiated transactions. During the~~ year ended December 31, 2024, ~~the~~included ~~Company~~in ~~repurchased 3.5 million shares of~~ the Company’s ~~common~~2024 ~~stock~~Annual ~~under the Repurchase Program and during the six-month period ended June 27, 2025 the Company repurchased approximately 4~~Report.~~5 million shares of the Company’s common stock for approximately $1.1 billion (which includes $4 million of excise taxes which will be paid in 2026) as part of the Repurchase Program.~~

As of June 27, 2025, approximately 12 million shares remained available for repurchase pursuant to the Repurchase Program, inclusive of 2024 and 2025 share repurchases. There is no expiration date for the Repurchase Program, and the timing and amount of any shares repurchased under the program will be determined by members of the Company’s management based on its evaluation of market conditions and other factors. The Repurchase Program may be suspended or discontinued at any time. Any repurchased shares will be available for use in connection with the Company’s equity compensation plans (or any successor plans) and for other corporate purposes. 20

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NOTE 13. STOCKHOLDERS' EQUITY AND STOCK-BASED COMPENSATION

Stockholders’ Equity

The Company’s Board of Directors has approved the following programs to repurchase shares of the Company’s common stock:

Name of program

Date of Board of Director approval

Number of shares of Company common stock approved for repurchase

Number of shares remaining available for repurchase as of September 26, 2025

2013 Repurchase Program

July 16, 2013

20,000,000

—

2024 Repurchase Program

July 22, 2024

20,000,000

2,000,000

2025 Repurchase Program

September 9, 2025

35,000,000

In each case, the approved program authorized or authorizes the repurchase of up to the specified number of shares of the Company’s common stock from time to time on the open market or in privately negotiated transactions. None of the repurchase programs were or are subject to an expiration date, and the timing and amount of any shares repurchased in the future will be determined by members of the Company’s management based on its evaluation of market conditions and other factors. Any repurchase program with remaining availability may be suspended or discontinued at any time. Repurchased shares are and will be available for use in connection with the Company’s equity compensation plans (or any successor plans) and for other corporate purposes.

During the three and nine-month periods ended September 27, 2024, the Company repurchased approximately 2.6 million and 20.0 million shares, respectively, of the Company’s common stock for $646 million and approximately $5.2 billion, respectively, inclusive of excise taxes as part of the 2013 Repurchase Program. Included within the shares repurchased under the 2013 Repurchase Program in the three and nine-month periods ended September 27, 2024 is the repurchase of $173 million of shares from the Danaher Corporation & Subsidiaries Pension Plan, a related party, at fair market value at the time of the purchase.

During the nine-month period ended September 26, 2025, the Company paid $56 million in excise taxes related to the 2024 share repurchases. Cash paid for excise taxes on share repurchases is included in all other financing activities in the accompanying Consolidated Condensed Statement of Cash Flows.

During the three and nine-month periods ended September 26, 2025, the Company repurchased 10.0 million and approximately 14.5 million shares, respectively, of the Company’s common stock for approximately $2.0 billion and $3.1 billion, respectively, (which includes $20 million and $24 million, respectively, of excise taxes which will be paid in 2026) as part of the 2024 Repurchase Program.

The following table summarizes the Company’s share activity (shares in millions):

Three-Month Period Ended

~~Six~~Nine-Month Period Ended

June 27, 2025

June 28, 2024

June 27, 2025

June 28, 2024

September 26, 2025

September 27, 2024

September 26, 2025

September 27, 2024

Common stock - shares issued:

Balance, beginning of period

885.69

~~882~~883.32

884.3

880.5

Common stock-based compensation awards

0.34

0.97

12.60

23.74

Balance, end of period

~~885~~886.93

883.29

~~885~~886.93

883.29

Stock-Based Compensation

For a full description of the Company’s stock-based compensation programs, refer to Note 18 of the Company’s financial statements as of and for the year ended December 31, 2024 included in the Company’s 2024 Annual Report. As of ~~June~~September 2726, 2025, approximately 43 million shares of the Company’s common stock were reserved for issuance under the 2007 Omnibus Incentive Plan.

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The following summarizes the components of the Company’s stock-based compensation expense ($ in millions):

	Three-Month Period Ended				~~Six~~Nine-Month Period Ended
	June 27, 2025		June 28, 2024		June 27, 2025		June 28, 2024
	September 26, 2025		September 27, 2024		September 26, 2025		September 27, 2024
RSUs/PSUs:
Pretax compensation expense	$	5349	$	4649	$	88137	$	78127
Income tax benefit	(1110)		(1011)		(1828)		(1627)
RSU/PSU expense, net of income taxes	4239		3638		70109		62100
Stock options:
Pretax compensation expense	3834		4135		6498		69104
Income tax benefit	(87)		(87)		(1320)		(1421)
Stock option expense, net of income taxes	3027		3328		5178		5583
Total stock-based compensation:
Pretax compensation expense	9183		8784		~~152~~235		~~147~~231
Income tax benefit	(1917)		(18)		(3148)		(3048)
Total stock-based compensation expense, net of income taxes	$	7266	$	6966	$	~~121~~187	$	~~117~~183

Stock-based compensation has been recognized as a component of SG&A expenses in the accompanying Consolidated Condensed Statements of Earnings. As of ~~June~~September 2726, 2025, $~~239~~190 million of total unrecognized compensation cost related to RSUs/PSUs is expected to be recognized over a weighted average period of approximately two years. As of ~~June~~September 2726, 2025, $~~202~~167 million of total unrecognized compensation cost related to stock options is expected to be recognized over a weighted average period of approximately two years. Future compensation amounts will be adjusted for any changes in estimated forfeitures.

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Accumulated Other Comprehensive Income

Accumulated OCI refers to certain gains and losses that under U.S. GAAP are included in comprehensive income (loss) but are excluded from net earnings as these amounts are initially recorded as an adjustment to stockholders’ equity. Foreign currency translation adjustments generally relate to indefinite investments in non-U.S. subsidiaries, as well as the impact from the Company’s hedges of its net investment in foreign operations, including the Company’s cross-currency swap derivatives, net of any income tax impacts.

The changes in accumulated OCI by component are summarized below ($ in millions).

	Foreign Currency Translation Adjustments		Pension and Postretirement Plan Benefit Adjustments			Cash Flow Hedge Adjustments			Accumulated Comprehensive Income (Loss)
For the Three-Month Period Ended June 27, 2025:
For the Three-Month Period Ended September 26, 2025:
Balance, March 28, 2025	$	(1,455)	$	(299)		$	142		$	(1,612)
OCI before reclassifications:
Increase (decrease)	979		—			(200)			779
Income tax impact	49		—			—			49
OCI before reclassifications, net of income taxes	1,028		—			(200)			828
Reclassification adjustments:
Increase (decrease)	—		2		(a)	213		(b)	215
Income tax impact	—		—			—			—
Reclassification adjustments, net of income taxes	—		2			213			215
Net OCI, net of income taxes	1,028		2			13			1,043
Balance, June 27, 2025	$	(427)	$	(297)		$	155		$	(569)
For the Three-Month Period Ended June 28, 2024:
Balance, March 29, 2024	$	(2,394)	$	(399)		$	49		$	(2,744)
OCI before reclassifications:
Increase (decrease)	~~133~~(65)		—			5549			~~188~~(16)
Income tax impact	(126)		—			—			(126)
OCI before reclassifications, net of income taxes	~~121~~(71)		—			5549			~~176~~(22)
Reclassification adjustments:
Increase (decrease)	—		2		(a)	~~(24)~~—		(b)	~~(22)~~2
Income tax impact	—		—			(1)			(1)
Reclassification adjustments, net of income taxes	—		2			(251)			~~(23)~~1
Net OCI, net of income taxes	~~121~~(71)		2			3048			~~153~~(21)
Balance, September 26, 2025	$	(498)	$	(295)		$	203		$	(590)
For the Three-Month Period Ended September 27, 2024:
Balance, June 28, 2024	$	(2,273)	$	(397)		$	79		$	(2,591)
OCI before reclassifications:
Increase (decrease)	1,193		—			(77)			1,116
Income tax impact	23		—			—			23
OCI before reclassifications, net of income taxes	1,216		—			(77)			1,139
Reclassification adjustments:
Increase (decrease)	—		3		(a)	140		(b)	143
Income tax impact	—		(1)			—			(1)
Reclassification adjustments, net of income taxes	—		2			140			142
Net OCI, net of income taxes	1,216		2			63			1,281
Balance, September 27, 2024	$	(1,057)	$	(395)		$	142		$	(1,310)

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	Foreign Currency Translation Adjustments		Pension and Postretirement Plan Benefit Adjustments			Cash Flow Hedge Adjustments			Accumulated Comprehensive Income (Loss)
For the Six-Month Period Ended June 27, 2025:
For the Nine-Month Period Ended September 26, 2025:
Balance, December 31, 2024	$	(2,904)	$	(300)		$	(14)		$	(3,218)
OCI before reclassifications:
Increase (decrease)	2,~~415~~350		—			(~~161~~112)			2,~~254~~238
Income tax impact	6256		—			—			6256
OCI before reclassifications, net of income taxes	2,~~477~~406		—			(~~161~~112)			2,~~316~~294
Reclassification adjustments:
Increase (decrease)	—		46		(a)	330		(b)	~~334~~336
Income tax impact	—		(1)			—(1)			(12)
Reclassification adjustments, net of income taxes	—		35			~~330~~329			~~333~~334
Net OCI, net of income taxes	2,~~477~~406		35			~~169~~217			2,~~649~~628
Balance, June 27, 2025	$	(427)	$	(297)		$	155		$	(569)
Balance, September 26, 2025	$	(498)	$	(295)		$	203		$	(590)
For the Six-Month Period Ended June 28, 2024:
For the Nine-Month Period Ended September 27, 2024:
Balance, December 31, 2023	$	(1,446)	$	(401)		$	99		$	(1,748)
OCI before reclassifications:
Increase (decrease)	~~(802)~~391		—			781			~~(724)~~392
Income tax impact	(252)		—			—			(252)
OCI before reclassifications, net of income taxes	~~(827)~~389		—			781			~~(749)~~390
Reclassification adjustments:
Increase (decrease)	—		58		(a)	~~(97)~~43		(b)	~~(92)~~51
Income tax impact	—		(12)			(1)			(23)
Reclassification adjustments, net of income taxes	—		46			~~(98)~~42			~~(94)~~48
Net OCI, net of income taxes	~~(827)~~389		46			~~(20)~~43			~~(843)~~438
Balance, June 28, 2024	$	(2,273)	$	(397)		$	79		$	(2,591)
Balance, September 27, 2024	$	(1,057)	$	(395)		$	142		$	(1,310)

(a) This accumulated other comprehensive income (loss) component is included in the computation of net periodic benefit cost (refer to Note 7 for additional details).

(b) Reflects reclassification to earnings related to cash flow hedges of certain long-term debt (refer to Note 11 for additional details).

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ITEM 2. MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS

Management’s Discussion and Analysis of Financial Condition and Results of Operations (“MD&A”) is designed to provide material information relevant to an assessment of Danaher Corporation’s (“Danaher,” the “Company,” “we,” “us” or “our”) financial condition and results of operations, including an evaluation of the amounts and certainty of cash flows from operations and from outside sources. The MD&A is designed to focus specifically on material events and uncertainties known to management that are reasonably likely to cause reported financial information not to be necessarily indicative of future operating results or of future financial condition. This includes descriptions and amounts of matters that have had a material impact on reported operations, as well as matters that are reasonably likely based on management’s assessment to have a material impact on future operations. The Company’s MD&A is divided into five sections:

•Information Relating to Forward-Looking Statements

•Overview

•Results of Operations

•Liquidity and Capital Resources

•Critical Accounting Estimates

You should read this discussion along with the Company’s MD&A and audited financial statements and Notes thereto as of and for the year ended December 31, 2024, included in the Company’s 2024 Annual Report and the Company’s Consolidated Condensed Financial Statements and related Notes as of and for the three and ~~six~~nine-month periods ended ~~June~~September 2726, 2025 included in this Quarterly Report on Form 10-Q (“Report”).

INFORMATION RELATING TO FORWARD-LOOKING STATEMENTS

Certain statements included or incorporated by reference in this Report, in other documents we file with or furnish to the Securities and Exchange Commission, in our press releases, webcasts, conference calls, presentations, materials delivered to shareholders and other communications, are “forward-looking statements” within the meaning of the U.S. federal securities laws. All statements other than historical factual information are forward-looking statements, including without limitation statements regarding: projections of tariff or other trade-related impacts, expected impacts of the U.S. government shutdown, revenue, expenses, profit, profit margins, asset values, pricing, tax rates, tax provisions, cash flows, pension and benefit obligations and funding requirements, our liquidity position or other projected financial measures; management’s plans and strategies for future operations, including statements relating to anticipated operating performance, customer demand, cost reductions, restructuring activities, new product and service developments, competitive strengths or market position, acquisitions and the integration thereof, divestitures, spin-offs, split-offs, initial public offerings, other securities offerings or other distributions, strategic opportunities, stock repurchases, dividends, executive compensation and potential executive stock sales or purchases; growth, declines and other trends in markets we sell into; future, new or modified laws, regulations, accounting pronouncements or public policy changes; regulatory approvals and the timing and conditionality thereof; outstanding claims, legal proceedings, tax audits and assessments and other contingent liabilities; future currency exchange rates and fluctuations in those rates; the potential or anticipated direct or indirect impact of public health crises, climate change, military or geopolitical conflicts or other man-made or natural disasters on our business, results of operations and/or financial condition; general economic and capital markets conditions; the anticipated timing of any of the foregoing; assumptions underlying any of the foregoing; and any other statements that address events or developments that Danaher intends or believes will or may occur in the future. Terminology such as “believe,” “anticipate,” “assume,” “continue,” “should,” “could,” “intend,” “will,” “plan,” “aim,” “expect,” “estimate,” “project,” “target,” “can,” “may,” “possible,” “potential,” “upcoming,” “forecast” and “positioned” and similar references to future periods are intended to identify forward-looking statements, although not all forward-looking statements are accompanied by such words.

Forward-looking statements are based on assumptions and assessments made by our management in light of their experience and perceptions of historical trends, current conditions, expected future developments and other factors. Forward-looking statements are not guarantees of future performance and actual results may differ materially from the results, developments and business decisions contemplated by our forward-looking statements. Accordingly, you should not place undue reliance on any such forward-looking statements. Important factors, risks and uncertainties that in the ~~future could cause actual results to differ materially from those envisaged in the forward-looking statements, and that in some cases have affected us in the past, include the following:~~

~~Business and Strategic Risks~~25

•Conditions in the global economy, the particular markets we serve and the financial markets can adversely affect our business and financial statements.

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future could cause actual results to differ materially from those envisaged in the forward-looking statements, and that in some cases have affected us in the past, include the following:

Business and Strategic Risks

•Conditions in the global economy, the particular markets we serve and the financial markets (including economic impacts from the U.S. government shutdown that began in October 2025) can adversely affect our business and financial statements.

•We face intense competition and if we are unable to compete effectively, we may experience decreased demand and decreased market share. Even if we compete effectively, we may be required to reduce the prices we charge.

•Our growth depends on the timely development and commercialization, and customer acceptance, of new and enhanced products and services based on technological innovation. Our growth also suffers when the markets into which we sell our products and services decline, do not grow as anticipated or experience cyclicality.

•The healthcare industry and related industries that we serve are undergoing significant changes in an effort to reduce (and increase the predictability of) costs, which can adversely affect our business and financial statements.

•Economic, political, geopolitical, legal, compliance, social and business factors (including the impact of military conflicts), both in the U.S. and outside the U.S., can negatively affect our business and financial statements. For example, elections can result in significant political shifts and/or disruptions, and the 2025 change in the U.S. administration as well as recent Supreme Court decisions have resulted in policy, regulatory and economic changes, challenges and uncertainty, including with respect to tariffs and healthcare-related topics. Delays in National Institutes of Health (“NIH”) funding related to the U.S. government shutdown that commenced in October 2025 may also negatively affect our business and financial statements.

•Uncertainties with respect to the development, deployment and use of artificial intelligence in our business and products may result in harm to our business and reputation.

•Global heath crises, pandemics, epidemics or other outbreaks can adversely impact certain elements of our business and financial statements.

•Business partners and other third-parties we rely on for development, supply and/or marketing of certain products, potential products and technologies could fail to perform sufficiently.

Acquisitions, Divestitures and Investment Risks

•The inability to consummate acquisitions at our historical rate and appropriate prices, realize the economic benefits of consummated acquisitions or to make appropriate investments that support our long-term strategy, can negatively impact our business. Our acquisition of businesses, investments, joint ventures and other strategic relationships can also negatively impact our business and financial statements and our indemnification rights may not fully protect us from liabilities related thereto.

•Divestitures or other dispositions could negatively impact our business, and contingent liabilities from businesses that we or our predecessors have previously disposed could adversely affect our business and financial statements. For example, we could incur significant liability if any of the split-off or spin-off transactions we have previously consummated are determined to be a taxable transaction or otherwise pursuant to our indemnification obligations with respect to such transactions.

Operational Risks

•Significant disruptions in, or breaches in security of, our information technology (“IT”) systems or data; data privacy violations; other losses or disruptions to facilities, supply chains, distribution systems or IT systems due to catastrophe; and labor disputes can all adversely affect our business and financial statements.

•Defects, manufacturing problems and unanticipated use or inadequate disclosure with respect to our products or services, or allegations thereof, can adversely affect our business and financial statements.

•Climate change, legal or regulatory measures to address climate change and other sustainability topics and any inability to address regulatory requirements or stakeholder expectations with respect to climate change and other sustainability topics, may negatively affect our business and financial statements.

•Our financial results are subject to fluctuations in the cost and availability of the supplies we use in, and the labor we need for, our operations, as well as adverse changes with respect to key distributors and channel partners.

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•Our success depends on our ability to recruit, retain and motivate talented employees.

•Our restructuring actions can have long-term adverse effects on our business and financial statements.

Intellectual Property Risks

•Any inability to adequately protect or avoid third-party infringement of our intellectual property, and third-party claims we are infringing intellectual property rights, can adversely affect our business and financial statements.

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•The U.S. government has certain rights with respect to incremental production capacity attributable to, and/or the intellectual property we have developed using, government financing. In addition, in times of national emergency the U.S. government could also control our allocation of manufacturing capacity.

Financial and Tax Risks

•From time to time our outstanding debt has increased significantly as a result of acquisitions and other factors, and we may incur additional debt. Such indebtedness may limit our operations and use of cash flow and negatively impact our credit ratings; and failure to comply with our indebtedness-related covenants could adversely affect our business and financial statements.

•Our business and financial statements can be adversely affected by foreign currency exchange rates, changes in our tax rates (including as a result of changes in tax laws) or income tax liabilities/assessments, the outcome of tax audits, recognition of impairment charges for our goodwill or other intangible assets and fluctuations in the cost and availability of commodities.

Legal, Regulatory, Compliance and Reputational Risks

•Significant developments or changes in national laws or policies to protect or promote domestic interests and/or address foreign competition can have an adverse effect on our business and financial statements.

•Our businesses are subject to extensive regulation (including those applicable to the healthcare industry). Failure to comply with those regulations (including by our employees, agents or business partners) or significant developments or changes in U.S. or non-U.S. laws or policies can adversely affect our business and financial statements.

•We are subject to, or otherwise responsible for, a variety of litigation and other legal and regulatory proceedings in the course of our business that can adversely affect our business and financial statements.

•With respect to the regulated medical devices we offer, product introductions or modifications can require regulatory clearance or authorizations and we can be required to recall or cease marketing such products; off-label marketing can result in penalties; and clinical trials can have results that are unexpected or are perceived unfavorably by the market, all of which can adversely affect our business and financial statements.

•Our operations, products and services also expose us to the risk of environmental, health and safety liabilities, costs and violations that can adversely affect our business and financial statements.

•Our By-law exclusive forum provisions could limit our stockholders’ ability to choose their preferred judicial forum for disputes.

See “Part I—Item 1A. Risk Factors” of the Company’s 2024 Annual Report and Part II-Item 1A of this report for further discussion regarding reasons that actual results may differ materially from the results, developments and business decisions contemplated by our forward-looking statements. Forward-looking statements speak only as of the date of the report, document, press release, webcast, call, presentation, materials or other communication in which they are made. Except to the extent required by applicable law, we do not assume any obligation to update or revise any forward-looking statement, whether as a result of new information, future events and developments or otherwise.

OVERVIEW

General

As a result of the Company’s geographic and industry diversity, the Company faces a variety of opportunities and challenges, including rapid technological development (particularly with respect to computing, automation, artificial intelligence, mobile connectivity and digitization) in most of the Company’s served markets, the expansion and evolution of opportunities in high-growth markets, trends and costs associated with a global labor force, consolidation of the Company’s competitors, ~~and~~ increasing regulation and a rapidly evolving global trade environment. The Company operates in a highly competitive business environment in most markets, and the Company’s long-term growth and profitability will depend in particular on its ability to expand its business in high-growth geographies and high-growth market segments, identify, consummate and integrate appropriate acquisitions and identify and consummate appropriate investments and strategic partnerships, develop innovative and differentiated new products and services with higher gross profit margins, expand and improve the effectiveness of the Company’s sales force, continue to reduce costs and improve operating efficiency and quality and effectively address the demands of an increasingly regulated global environment. The Company is making significant investments, organically and through acquisitions and investments, to address the rapid pace of technological change in its served markets and to globalize its manufacturing, research and development and customer-facing resources (particularly in high-growth markets) to be responsive to the Company’s customers throughout the world and improve the efficiency of the Company’s operations.

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strategic partnerships, develop innovative and differentiated new products and services with higher gross profit margins, expand and improve the effectiveness of the Company’s sales force, continue to reduce costs and improve operating efficiency and quality and effectively address the demands of an increasingly regulated global environment and the evolving trade environment. The Company is making significant investments, organically and through acquisitions and investments, to address the rapid pace of technological change in its served markets and to position its manufacturing, research and development and customer-facing resources to be responsive to the Company’s customers throughout the world and improve the efficiency of the Company’s operations.

Business Performance and Outlook

During the ~~second~~third quarter of 2025, the Company’s overall revenues and core sales increased 34.5% and 3.0%, respectively, compared to the comparable period of 2024. ~~Core~~For the nine-month period ended September 26, 2025, overall revenues and core sales increased 12.5% inand ~~the~~1.5%, ~~second~~respectively, ~~quarter of 2025~~ compared to the comparable prior year period. In asboth periods, the increase in core sales is due to higher core sales in the Biotechnology and Diagnostics segments that were partially offset by lower core sales in the Life Sciences segment. ~~The~~In ~~impact~~the ofthree ~~foreign~~and ~~currency increased reported sales by 2.0%. For the six~~nine-month ~~period~~periods ended ~~June~~September 2726, 2025, ~~overall revenues increased 1.0% compared to~~ the ~~comparable~~impact ~~prior~~of ~~year~~foreign ~~period~~currency ~~due~~increased toreported ~~higher core~~ sales ~~in the Biotechnology segment that were partially offset~~ by ~~lower~~1.5% ~~core~~and ~~sales~~1.0%, ~~in the Life Sciences segment~~respectively. Price increases contributed 0.5% to sales growth on a year-over-year basis during both the three and nine-month ~~period~~periods ended ~~June~~September 2726, 2025 and are reflected as a component of core sales above. ~~Price increases did not have a significant impact on the change in sales on a year-over-year basis during the six-month period ended June 27, 2025.~~ For the definitions of “core sales” and “acquisitions” refer to “—Results of Operations” below.

Geographically, the Company’s sales in the three-month period ended ~~June~~September 2726, 2025 in developed markets increased year-over-year by 5% and core sales in developed markets were up ~~low~~mid-single digits, primarily due to ~~high~~mid-single digit core sales increases in ~~Western~~North ~~Europe~~America. The increase in core sales in developed markets was primarily driven by increases in the ~~Biotechnology~~Diagnostics ~~segment~~ and toBiotechnology ~~a lesser extent in the Diagnostics segment~~segments, partially offset by decreased year-over-year core sales in the Life Sciences segment. For the same period, sales ~~and core sales~~ in high-growth markets ~~were~~increased ~~flat~~ year-over-year by 2% and core sales were up low-single digits as a mid-single digit decline in core revenue in China was more than offset by increased core sales in other regions. ~~The~~In ~~Diagnostics~~the ~~and~~high-growth markets, the Life Sciences and Biotechnology segments’ increase in demand ~~in the high-growth markets~~ was partially offset by core sales declines in the ~~Biotechnology~~Diagnostics segment. High-growth markets represented approximately 29% of the Company’s total sales in the ~~second~~third quarter of 2025. For additional information regarding the Company’s sales by geographical region during the three and ~~six~~nine-month periods ended ~~June~~September 2726, 2025 and ~~June~~September 2827, 2024, refer to Note 4 to the accompanying Consolidated Condensed Financial Statements.

The Company’s net earnings for the three and ~~six~~nine-month periods ended ~~June~~September 2726, 2025 totaled $~~555~~908 million and approximately $12.54 billion, or $01.7727 and $23.1037 per diluted common share, respectively, compared to $~~907~~818 million and approximately $2.08 billion, or $1.2212 and $23.6880 per diluted common share, respectively, for the three and ~~six~~nine-month periods ended ~~June~~September 2827, 2024. Impairment charges of $~~432~~548 million ($~~328~~409 million after-tax or $0.4657 per diluted common share) recorded in the nine-month period ended September 26, ~~and~~2025, net of impairment charges of $~~447~~222 million ($~~339~~169 million after-tax or $0.4723 per diluted common share), recorded in the ~~three~~nine-month period ended September 27, 2024, and ~~six~~investment losses in the nine-month ~~periods~~period ended ~~June~~September 2726, 2025, ~~respectively~~net of investment gains in the nine-month period ended September 27, ~~drove~~2024, were the primary reasons for the year-over-year decline in net earnings and diluted net earnings per common share for the ~~three and six~~nine-month ~~periods~~period ended ~~June~~September 2726, 2025.

Currency exchange rates increased reported sales by approximately 21.5% and 1.0% for the three and nine-month ~~period~~periods ended ~~June~~September 2726, 2025, respectively, compared to the comparable ~~period~~periods of 2024, primarily due to the exchange rates of the U.S. dollar compared to the euro and other major currencies ~~in the second quarter of 2025~~. ~~Currency exchange rates did not have a significant impact on the change in sales on a year-over-year basis during the six-month period ended June 27, 2025.~~ In future periods, strengthening of the U.S. dollar against other major currencies compared to the exchange rates in effect as of ~~June~~September 2726, 2025 would adversely impact the Company’s sales and results of operations on an overall basis, and weakening of the U.S. dollar against other major currencies compared to the exchange rates in effect as of ~~June~~September 2726, 2025 would positively impact the Company’s sales and results of operations. In addition to the translational exchange rate risk to sales, the Company also faces transactional exchange rate risk from transactions with customers in countries outside the U.S. and from intercompany transactions between affiliates. Transactional exchange rate risk (and any resulting gains or losses) arises from the purchase and sale of goods and services in currencies other than the Company’s functional currency or the functional currency of its applicable subsidiary.

~~As a diversified, global business,~~ Danaher operates a diversified global supply chain and sources parts and materials globally. InDuring ~~the second quarter of~~ 2025, the U.S. has implemented significant new tariffs on imports from a wide range of countries, which has also prompted retaliatory tariffs by a number of countries, including tariffs and aexport ~~cycle~~restrictions ofon ~~retaliatory~~certain ~~tariffs~~manufacturing components imposed by ~~both~~China and tariffs pursuant to trade agreements the U.S. ~~and~~has ~~other~~entered into with certain countries. ~~Subsequently~~In addition, ~~actions~~a ~~were~~number ~~taken~~of bynew tariffs have been threatened and the U.S. and ~~certain~~ other countries continue to ~~modify~~negotiate ~~certain~~trade ofarrangements ~~these tariffs~~ and~~/or~~ ~~delay~~tariff ~~their~~levels. In ~~effective~~August ~~dates~~2025, ~~but~~the aU.S. ~~number~~Court of ~~new~~Appeals ~~tariffs~~for ~~remain~~the inFederal ~~effect,~~Circuit ~~including~~ruled ~~significant~~against ~~tariffs~~certain ~~between~~of the U.S. ~~and~~tariffs ~~China. In~~that ~~addition,~~have abeen ~~number~~implemented. The ofU.S. ~~new~~administration ~~tariffs~~has ~~have~~appealed ~~been~~this ~~threatened~~ruling and the U.S. ~~and~~Supreme ~~other~~Court ~~countries~~has ~~continue~~agreed to ~~negotiate~~hear ~~trade~~the ~~arrangements~~case, ~~and~~with ~~tariff~~oral ~~levels.~~arguments anticipated in November 2025.

Based on the tariffs enacted and in effect as of July 20, 2025 (the “enacted tariffs”), the Company anticipates incurring incremental tariff costs for the full year 2025 of several hundred millions of dollars. These incremental costs from the enacted tariffs reflect their impact on the costs of parts and materials used by the Company to produce products, as well as costs the Company may incur on finished goods shipped to customers. The Company expects to largely offset the operating profit impact of the enacted tariffs with manufacturing footprint changes, supply chain adjustments, surcharges and additional productivity and cost savings actions. To the extent the Company is unable to offset the incremental cost from the enacted tariffs, or the enacted tariffs negatively impact demand, the Company’s revenue and profitability would be adversely impacted. If the delayed tariffs come into effect or other additional tariffs are adopted, the Company would 28

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Based on the tariffs enacted and in effect as of October 19, 2025 (the “enacted tariffs”), the Company anticipates incurring incremental tariff costs for the full year 2025 of several hundred million dollars. These incremental costs from the enacted tariffs reflect their impact on the costs of parts and materials used by the Company to produce products, as well as costs the Company incurs on finished goods shipped to customers. The Company expects to, and has thus far, largely offset the operating profit impact of the enacted tariffs with manufacturing footprint changes, supply chain adjustments, surcharges and additional productivity and cost savings actions. To the extent the Company is unable to continue to offset the incremental cost from the enacted tariffs, the enacted tariffs negatively impact demand or the export restrictions negatively impact manufacturing, the Company’s revenue and profitability would be adversely impacted. If delayed tariffs come into effect or other additional tariffs are adopted, the Company would incur additional tariff costs that could be material and the Company’s revenue and profitability could be adversely impacted.

In addition to changes in trade policy, the new U.S. administration has implemented a number of other regulatory, policy and personnel changes, including the elimination, downsizing and reduced funding of certain government agencies and programs and the cancellation or delay of government contracts and research grants, each of which may be exacerbated by the U.S. government shutdown that began in October 2025. In addition, the administration has changed the composition of and guidance from advisory panels on healthcare practices.

The full impact of the matters noted above on the Company, our customers, end-users and business partners, the overall economy and capital markets remains uncertain. The Company currently expects academic and government demand to remain weaker, with ongoing uncertainty around research funding and a cautious bioprocessing equipment spending environment. Refer to “Risk Factors” for additional information.

RESULTS OF OPERATIONS

Non-GAAP Measures

In this report, references to the non-GAAP measure of core sales (also referred to as core revenues or sales/revenues from existing businesses) refer to sales calculated according to U.S. GAAP, but excluding:

•sales from acquired businesses (as defined below); and

•the impact of currency translation.

References to sales or operating profit attributable to acquisitions or acquired businesses refer to sales or operating profit, as applicable, from acquired businesses recorded prior to the first anniversary of the acquisition less any sales and operating profit, during the applicable period, attributable to divested product lines not considered discontinued operations. The portion of revenue attributable to currency translation is calculated as the difference between:

•the period-to-period change in revenue (excluding sales from acquired businesses (as defined above)); and

•the period-to-period change in revenue (excluding sales from acquired businesses (as defined above)) after applying current period foreign exchange rates to the prior year period.

Core sales growth (decline) should be considered in addition to, and not as a replacement for or superior to, sales, and may not be comparable to similarly titled measures reported by other companies. Management believes that reporting this non-GAAP financial measure provides useful information to investors by helping identify underlying growth trends in Danaher’s business and facilitating comparisons of Danaher’s revenue performance with its performance in prior and future periods and to Danaher’s peers. Management also uses this non-GAAP financial measure to measure the Company’s operating and financial performance and uses core sales growth as one of the performance measures in the Company’s executive short-term cash incentive compensation program. The Company excludes the effect of currency translation from this measure because currency translation is not under management’s control, is subject to volatility and can obscure underlying business trends. The Company excludes the effect of acquisitions and divestiture-related items because the nature, size, timing and number of acquisitions and divestitures can vary dramatically from period-to-period and between the Company and its peers and can also obscure underlying business trends and make comparisons of long-term performance difficult.

Throughout this discussion, references to sales growth or decline refer to the impact of both price and unit sales and references to productivity improvements generally refer to improved cost-efficiencies resulting from the ongoing application of the Danaher Business System.

~~Sales Growth and Core Sales Growth~~29

	% Change Three-Month Period Ended June 27, 2025 vs. Comparable 2024 Period		% Change Six-Month Period Ended June 27, 2025 vs. Comparable 2024 Period
Total sales growth (GAAP)	3.5	%	1.0	%
Impact of:
Currency exchange rates	(2.0)	%	—	%
Core sales growth (non-GAAP)	1.5	%	1.0	%

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Sales Growth and Core Sales Growth


	% Change Three-Month Period Ended September 26, 2025 vs. Comparable 2024 Period		% Change Nine-Month Period Ended September 26, 2025 vs. Comparable 2024 Period
Total sales growth (GAAP)	4.5	%	2.5	%
Impact of:

Currency exchange rates	(1.5)	%	(1.0)	%
Core sales growth (non-GAAP)	3.0	%	1.5	%

Operating Profit Performance

Operating profit margins ~~decreased~~increased ~~750~~260 basis points from 2016.35% during the three-month period ended ~~June~~September 2827, 2024 to 1219.81% for the three-month period ended ~~June~~September 2726, 2025.

~~Second~~Third quarter 2025 vs. ~~second~~third quarter 2024 operating profit margin comparisons were ~~unfavorably~~favorably impacted by:

•~~Second~~Third quarter ~~2025~~2024 impairment charge related to a trade name in the Life Sciences segment, net of impairment charges related to technology and other assets in the Biotechnology segment and a trade name in the Diagnostics segment in the third quarter of 2025. Refer to Note 8 to the accompanying Consolidated Condensed Financial Statements for additional information regarding the impairments - ~~730~~220 basis points

•~~Incremental~~Higher ~~dilutive~~2025 ~~effect~~core insales, ~~2025~~net of ~~acquired businesses and~~ the impact of achanges ~~product~~in ~~line~~leverage ~~disposition~~from ~~which~~the ~~did~~Company’s ~~not~~operations ~~qualify~~and asadministrative ~~discontinued~~cost ~~operations~~structure and the impact of product mix - 3045 basis points

~~Second~~Third quarter 2025 vs. ~~second~~third quarter 2024 operating profit margin comparisons were ~~favorably~~unfavorably impacted by:

•~~Higher~~Incremental ~~2025~~dilutive ~~core~~effect ~~sales~~in ~~and~~2025 ~~changes~~of inacquired ~~leverage~~businesses ~~from~~and the ~~Company’s~~impact ~~operations~~of ~~and~~a ~~administrative~~product ~~cost~~line ~~structure,~~disposition ~~net~~which ofdid ~~the~~not ~~impact~~qualify ofas ~~currency~~discontinued ~~exchange~~operations ~~rates~~ - 105 basis points

Operating profit margins decreased ~~410~~180 basis points from 2119.58% during the ~~six~~nine-month period ended ~~June~~September 2827, 2024 to 1718.40% for the ~~six~~nine-month period ended ~~June~~September 2726, 2025.

Year-to-date 2025 vs. year-to-date 2024 operating profit margin comparisons were unfavorably impacted by:

•First ~~half~~nine months of 2025 impairment charges related to a trade ~~name~~names in the Life Sciences ~~segment~~and Diagnostics segments, and impairment charges related to technology, other intangible assets and a facility in the Biotechnology segment, net of an impairment charge related to a trade name in the Life Sciences segment in the first nine months of 2024 - ~~385~~180 basis points

•Incremental dilutive effect in 2025 of acquired businesses and the impact of a product line disposition which did not qualify as discontinued operations - 3020 basis points

•The impact of product mix, changes in leverage from the Company’s operations and administrative cost structure and the impact of currency exchange rates, net of higher 2025 core sales - 15 basis points

Year-to-date 2025 vs. year-to-date 2024 operating profit margin comparisons were favorably impacted by:

•First ~~half~~nine months of 2024 acquisition-related fair value adjustment to inventory - 2015 basis points

•Higher 2025 core sales and the impact of product mix, net of the impact of changes in leverage from the Company’s operations and administrative cost structure and the impact of currency exchange rates - 5 basis points

Business Segments

Sales by business segment for each of the periods indicated were as follows ($ in millions):

Three-Month Period Ended

~~Six~~Nine-Month Period Ended

June 27, 2025

June 28, 2024

June 27, 2025

June 28, 2024

September 26, 2025

September 27, 2024

September 26, 2025

September 27, 2024

Biotechnology

1,~~850~~798

1,~~713~~653

35,~~462~~260

34,~~237~~890

Life Sciences

1,~~777~~792

1,~~770~~782

35,~~457~~249

35,~~515~~297

Diagnostics

2,~~309~~463

2,~~260~~363

47,~~758~~221

47,~~787~~150

Total

56,~~936~~053

5,~~743~~798

1117,~~677~~730

1117,~~539~~337

For information regarding the Company’s sales by geographical region, refer to Note 4 to the accompanying Consolidated Condensed Financial Statements.

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BIOTECHNOLOGY

The Biotechnology segment includes the bioprocessing and discovery and medical businesses and offers a broad range of equipment, consumables and services that are primarily used by customers to advance and accelerate the research, development, manufacture and delivery of biological medicines. The Company’s solutions support a broad range of biotherapeutics including monoclonal antibodies, recombinant proteins, replacement therapies such as insulin and vaccines, as well as novel cell, gene, mRNA and other nucleic acid therapies.

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Biotechnology Selected Financial Data

	Three-Month Period Ended						~~Six~~Nine-Month Period Ended
($ in millions)	~~June~~September 2726, 2025			~~June~~September 2827, 2024			~~June~~September 2726, 2025			~~June~~September 2827, 2024
Sales	$	1,~~850~~798		$	1,~~713~~653		$	35,~~462~~260		$	34,~~237~~890
Operating profit	~~531~~352			~~462~~390			~~972~~1,324			~~787~~1,177
Depreciation	38			3536			72110			77113
Amortization of intangible assets	~~228~~231			~~214~~218			~~441~~672			~~432~~650
Operating profit as a % of sales	2819.76		%	2723.06		%	2825.12		%	24.31		%
Depreciation as a % of sales	2.1		%	2.02		%	2.1		%	2.43		%
Amortization as a % of sales	12.38		%	1213.52		%	12.78		%	13.3		%

Sales Growth and Core Sales Growth

	% Change Three-Month Period Ended June 27, 2025 vs. Comparable 2024 Period		% Change Six-Month Period Ended June 27, 2025 vs. Comparable 2024 Period
	% Change Three-Month Period Ended September 26, 2025 vs. Comparable 2024 Period		% Change Nine-Month Period Ended September 26, 2025 vs. Comparable 2024 Period
Total sales growth (GAAP)	89.0	%	7.05	%
Impact of:
Currency exchange rates	(2.05)	%	(01.50)	%
Core sales growth (non-GAAP)	6.05	%	6.5	%

Price increases in the segment contributed 2.5% and 2.0%, respectively, to sales growth on a year-over-year basis during the three and ~~six~~nine-month periods ended ~~June~~September 2726, 2025 and are reflected as a component of core sales above.

Total segment sales increased 89.0% and 7.05% during the three and ~~six~~nine-month periods, respectively. The increase in segment sales in the three and ~~six~~nine-month periods was led by increased core sales and to a lesser extent by the impact of currency exchange rates. The year-over-year increase in total segment core sales in both periods was led by increased sales of consumables, partially offset by declines in equipment sales ~~in both periods~~. Geographically, the increase in core sales was led by North America in the three-month period and North America and Western Europe in ~~both~~the ~~periods~~nine-month period. Based on the current market conditions, the Company expects a cautious equipment spending environment through the remainder of the year.

The year-over-year increase in core sales in the segment was led by high-single digit increases in core sales in the bioprocessing business in both the three and ~~six~~nine-month periods and was primarily driven by improved consumables demand from large pharmaceutical customers, ~~primarily in Western Europe,~~ partially offset by lower year-over-year demand for equipment ~~across most major markets~~. Core sales in the discovery and medical business ~~decreased~~increased year-over-year as demand for medical and lab filtration consumables more than offset lower demand for protein research equipment in the life science research end-markets ~~more than offset the improved demand for consumables~~.

Operating Profit Performance

Operating profit margins ~~increased~~decreased ~~170~~400 basis points during the three-month period ended ~~June~~September 2726, 2025 as compared to the comparable period of 2024 due to higher 2025 core sales, the impact of product mix and the impact of changes in leverage in the segment’s operational and administrative cost structure, net of the impact of currency exchange rates.

~~Operating~~Third ~~profit~~quarter ~~margins~~2025 ~~increased~~vs. ~~380~~third ~~basis~~quarter ~~points~~2024 ~~during~~operating ~~the~~profit ~~six-month~~margin ~~period~~comparisons ~~ended~~were ~~June 27,~~unfavorably ~~2025~~impacted ~~as compared to the comparable period of 2024.~~by:

•Third quarter 2025 impairment charge related to technology and other intangible assets - 475 basis points

Third quarter 2025 vs. third quarter 2024 operating profit margin comparisons were favorably impacted by:

•Higher third quarter 2025 core sales and the impact of product mix, net of the impact of changes in leverage from the Company’s operations and administrative cost structure and the impact of currency exchange rates - 75 basis points

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Operating profit margins increased 110 basis points during the nine-month period ended September 26, 2025 as compared to the comparable period of 2024.

Year-to-date 2025 vs. year-to-date 2024 operating profit margin comparisons were favorably impacted by:

•Higher 2025 core sales, and the impact of product mix ~~and improvements in the segment’s operational and administrative cost structure~~, net of the impact of currency exchange rates - ~~425~~300 basis points

Year-to-date 2025 vs. year-to-date 2024 operating profit margin comparisons were unfavorably impacted by:

•First ~~half~~nine months of 2025 impairment ~~charge~~charges related to atechnology, ~~facility~~other inintangible ~~the~~assets ~~Biotechnology~~and ~~segment~~a facility - 45190 basis points

Amortization of intangible assets as a percentage of sales decreased during both the three and ~~six~~nine-month periods ended ~~June~~September 2726, 2025 as compared to the comparable periods of 2024, primarily as a result of the increase in sales.

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LIFE SCIENCES

The Life Sciences segment offers a broad range of instruments, consumables, services and software that are primarily used by customers to study the basic building blocks of life, including DNA and RNA, nucleic acid, proteins, metabolites and cells, in order to understand the causes of disease, identify new therapies, and test and manufacture new drugs, vaccines and gene editing technologies. Additionally, the segment provides products and consumables used to filter and remove contaminants from a variety of liquids and gases in many end-market applications.

As discussed in Note 8 to the accompanying Consolidated Condensed Financial Statements, during the third quarter of 2025, the Company reorganized and integrated certain businesses within its Life Sciences segment to better serve the Company’s customers in new market segments and to respond to current market conditions. The life sciences instruments business includes the flow cytometry and lab automation solutions business, the mass spectrometry business and the microscopy business. The life science consumables business includes the genomic medicines businesses and the protein consumables business.

Life Sciences Selected Financial Data

	Three-Month Period Ended						~~Six~~Nine-Month Period Ended
($ in millions)	~~June~~September 2726, 2025			~~June~~September 2827, 2024			~~June~~September 2726, 2025			~~June~~September 2827, 2024
Sales	$	1,~~777~~792		$	1,~~770~~782		$	35,~~457~~249		$	35,~~515~~297
Operating profit (loss)	(239)			233			(38)			468
Operating profit	222			35			184			503
Depreciation	4547			4144			90137			79123
Amortization of intangible assets	~~150~~154			~~140~~147			~~299~~453			~~281~~428
Operating profit (loss) as a % of sales	(13.4)		%	13.2		%	(1.1)		%	13.3		%
Operating profit as a % of sales	12.4		%	2.0		%	3.5		%	9.5		%
Depreciation as a % of sales	2.56		%	2.35		%	2.6		%	2.23		%
Amortization as a % of sales	8.46		%	78.92		%	8.6		%	8.01		%

Sales Growth (Decline) and Core Sales Decline

	% Change Three-Month Period Ended June 27, 2025 vs. Comparable 2024 Period		% Change Six-Month Period Ended June 27, 2025 vs. Comparable 2024 Period
	% Change Three-Month Period Ended September 26, 2025 vs. Comparable 2024 Period		% Change Nine-Month Period Ended September 26, 2025 vs. Comparable 2024 Period
Total sales growth (decline) (GAAP)	0.5	%	(1.50)	%
Impact of:
Acquisitions	~~(1.5)~~—	%	(1.50)	%
Currency exchange rates	(1.5)	%	(0.5)	%
Core sales decline (non-GAAP)	(21.50)	%	(32.5)	%

Price increases in the segment contributed 1.0% and 0.5% to the change in sales on a year-over-year basis during ~~both~~ the three and ~~six~~nine-month periods ended ~~June~~September 2726, 2025, respectively, and are reflected as a component of core sales above.

Total segment sales increased 0.5% and decreased 1.5% during the three and six-month periods ended June 27, 2025, respectively. The sales increase during the three-month period was driven by the impact of an acquisition and currency exchange rates, partially offset by a decline in core sales. The sales decline during the six-month period was primarily a result of decreased core sales, partially offset by the impact of acquisitions and to a lesser extent the impact of currency exchange rates. The year-over-year decrease in total segment core sales in both the three and six-month periods was driven by declines in both consumables and equipment. Lower funding levels at emerging biotechnology customers and in the academic and government end-markets reduced demand for the segment’s products in both periods. Geographically, the core sales decline was led by North America in both periods. 32

The year-over-year decrease in segment core sales in the three and six-month periods was led by the genomics consumables business, primarily in North America, driven by lower demand for the plasmids and protein product lines at two large customers and lower funding levels at emerging biotechnology and academic research customers. Lower year-over-year demand in the academic and government end-markets reduced core sales in the protein consumables and in the flow cytometry and lab automation solutions businesses in both the three and six-month periods. Core sales declined year-over-year in both periods in the microscopy and mass spectrometry businesses as decreased demand for equipment more than offset increased demand for consumables. During both periods, year-over-year core sales increased in the filtration business, where increased demand in the microelectronic and aerospace end-markets more than offset decreased demand in the energy-related end-market.

Operating Profit (Loss) Performance

Operating profit margins decreased 2,660 basis points during the three-month period ended June 27, 2025 as compared to the comparable period of 2024. The following factors unfavorably impacted year-over-year operating profit margin:

•Second quarter 2025 impairment charge related to a trade name. Refer to Note 8 to the accompanying Consolidated Condensed Financial Statements for additional information - 2,430 basis points

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~~•Lower~~Total ~~second~~segment ~~quarter~~sales increased 0.5% and decreased 1.0% during the three and nine-month periods ended September 26, 2025, respectively. The sales increase during the three-month period was driven by currency exchange rates, partially offset by a decline in core sales. The sales decline during the nine-month period was primarily a result of decreased core sales, partially offset by the impact of ~~changes~~acquisitions and to a lesser extent, the impact of currency exchange rates. The year-over-year decrease in ~~leverage~~total segment core sales in the three-month period ended September 26, 2025 was driven by a decline in consumables sales, partially offset by increased demand for equipment. In the nine-month period ended September 26, 2025, the year-over-year decrease in total segment’s ~~operational~~core sales was driven by declines in both consumables and ~~administrative~~equipment ~~cost~~sales. Lower ~~structure~~funding levels at emerging biotechnology customers and in the ~~impact~~academic ofand ~~product~~government ~~mix~~ end-markets ~~155~~reduced ~~basis~~demand ~~points~~for the segment’s products in both periods. Geographically, the core sales decline in both periods was led by North America.

•The ~~incremental~~year-over-year ~~dilutive~~decrease ~~effect~~in segment core sales in ~~2025~~the ofthree ~~acquired~~and nine-month periods was led by the life science consumables businesses, primarily in North America, driven by lower demand for the plasmids and mRNA product lines at two large customers and lower funding levels at emerging biotechnology and academic research customers. In the life science instruments businesses, core sales increased in the three-month 75period ~~basis~~and ~~points~~decreased in the nine-month period, as declines in equipment demand in both periods was more than offset by increased demand for consumables and software in the three-month period. In both periods, core sales in the microscopy and mass spectrometry businesses decreased, while core sales at the flow cytometry and lab automation solutions business increased. During both periods, year-over-year core sales increased in the filtration business. In the three-month period, core sales in filtration increased in all major end-markets while in the nine-month period, increased demand in the microelectronic and aerospace end-markets more than offset decreased year-over-year demand in the energy-related end-market.

Operating ~~profit~~Profit ~~margins decreased 1,440 basis points during the six-month period ended June 27, 2025 as compared to the comparable period of 2024.~~ Performance

Operating profit margins increased 1,040 basis points during the three-month period ended September 26, 2025 as compared to the comparable period of 2024.

Third quarter 2025 vs. third quarter 2024 operating profit margin comparisons were favorably impacted by:

•Third quarter 2024 impairment charge related to a trade name - 1,245 basis points

Third quarter 2025 vs. third quarter 2024 operating profit margin comparisons were unfavorably impacted by:

•Lower third quarter 2025 core sales, the impact of product mix and the impact of changes in leverage from the segment’s operational and administrative cost structure, net of the impact of currency exchange rates - 205 basis points

Operating profit margins decreased 600 basis points during the nine-month period ended September 26, 2025 as compared to the comparable period of 2024.

Year-to-date 2025 vs. year-to-date 2024 operating profit margin comparisons were unfavorably impacted by:

•First ~~half~~nine months of 2025 impairment charge related to a trade name, net of an impairment charge related to a trade name in the first nine months of 2024 - ~~1,250~~405 basis points

•Lower ~~first half of~~ 2025 core sales, the impact of product mix, and the impact of changes in leverage infrom the segment’s operational and administrative cost structure ~~and the impact of currency exchange rates~~ - ~~200~~205 basis points

•The incremental dilutive effect in 2025 of acquired businesses - 6035 basis points

Year-to-date 2025 vs. year-to-date 2024 operating profit margin comparisons were favorably impacted by:

•First ~~half~~nine months of 2024 acquisition-related fair value adjustment to inventory - 7045 basis points

Depreciation and amortization of intangible assets increased as a percentage of sales during both the three and ~~six~~nine-month periods ended ~~June~~September 2726, 2025, primarily asdue ato ~~result of~~ the ~~decrease in sales and the~~ impact of acquisitions.

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DIAGNOSTICS

The Diagnostics segment offers clinical instruments, consumables, software and services that hospitals, physicians’ offices, reference laboratories and other critical care settings use to diagnose disease and make treatment decisions.

Diagnostics Selected Financial Data

	Three-Month Period Ended						~~Six~~Nine-Month Period Ended
($ in millions)	~~June~~September 2726, 2025			~~June~~September 2827, 2024			~~June~~September 2726, 2025			~~June~~September 2827, 2024
Sales	$	2,~~309~~463		$	2,~~260~~363		$	47,~~758~~221		$	47,~~787~~150
Operating profit	~~554~~665			~~556~~615			1,~~272~~937			12,~~386~~001
Depreciation	~~100~~101			~~100~~95			~~200~~301			~~197~~292
Amortization of intangible assets	48			4849			96144			96145
Operating profit as a % of sales	2427.0		%	2426.60		%	26.78		%	2928.0		%
Depreciation as a % of sales	4.31		%	4.40		%	4.2		%	4.1		%
Amortization as a % of sales	2.1.9		%	2.1		%	2.0		%	2.0		%

Sales Growth ~~(Decline)~~ and Core Sales Growth

	% Change Three-Month Period Ended June 27, 2025 vs. Comparable 2024 Period		% Change Six-Month Period Ended June 27, 2025 vs. Comparable 2024 Period
	% Change Three-Month Period Ended September 26, 2025 vs. Comparable 2024 Period		% Change Nine-Month Period Ended September 26, 2025 vs. Comparable 2024 Period
Total sales growth (decline) (GAAP)	2.0	%	(0.5)	%
Total sales growth (GAAP)	4.0	%	1.0	%
Impact of:
Divestitures	0.5	%	0.5	%
Currency exchange rates	(01.50)	%	—	%
Core sales growth (non-GAAP)	23.05	%	—1.5	%

Price decreases in the segment of 1.5% and 1.0%, attributable to the impact of sales promotions and factors discussed below, negatively impacted the year-over-year change in sales during both the three and ~~six~~nine-month periods ended ~~June~~September 2726, 2025, respectively, and are reflected as a component of core sales above.

Total segment sales increased 24.0% during the three-month period primarily as a result of increased core sales and to a lesser extent, currency exchange rates, net of the impact of divestitures. Total segment sales ~~decreased~~increased 01.50% during the ~~six~~nine-month period primarily as a result of increased core sales, net of the impact of divestitures. In the three and nine-month ~~period~~periods, the increase in segment core sales was primarily driven by increased year-over-year demand for consumables~~, partially offset by decreased demand for equipment~~. ~~In the six-month period, core sales were flat as increased year-over-year demand for consumables was offset by lower demand for equipment.~~ Geographically, increased core sales in North America and most other major markets were partially offset by decreased core sales in China in both periods attributable to the pricing impact of China’s volume-based procurement program and healthcare reimbursement changes ~~in both periods~~.

31During the three-month period, core sales growth in the molecular diagnostics business increased year-over-year primarily due to increased core sales in respiratory tests. During the nine-month period, core sales increased year-over-year as increased core sales of non-respiratory tests more than offset decreased core sales of respiratory tests. The Company believes that third quarter 2025 demand for respiratory tests was driven in part by customers purchasing in preparation for the upcoming respiratory season, which may adversely impact demand for such tests in the fourth quarter of 2025. In the segment’s clinical diagnostics businesses core sales increased during both the three and nine-month periods on a year-over-year basis, led by the pathology diagnostics business. In the clinical lab business, increased year-over-year core sales outside of China, led by North America, more than offset core sales declines in China in both the three and nine-month periods, due to the impact of China’s volume-based procurement program and healthcare reimbursement changes.

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During the three-month period, core sales growth in the molecular diagnostics business increased year-over-year as core sales in non-respiratory tests more than offset decreased core sales of respiratory tests, while during the six-month period, core sales declined year-over-year as decreased core sales of respiratory tests more than offset increased core sales of non-respiratory tests. In the segment’s clinical diagnostics businesses core sales for all the businesses increased during both the three and six-month periods on a year-over-year basis. In the clinical lab business, increased year-over-year sales outside of China, led by North America, more than offset core sales declines in China in both the three and six-month periods, due to the impact of China’s volume-based procurement and healthcare reimbursement changes.

Operating Profit Performance

Operating profit margin ~~decreased~~increased 60100 basis points during the three-month period ended ~~June~~September 2726, 2025 as compared to the comparable period of 2024. ~~The following factors unfavorably impacted year-over-year operating profit margin:~~

~~•The~~Third ~~impact of product mix, partially offset by higher second~~ quarter 2025 ~~core~~vs. ~~sales~~third ~~and~~quarter ~~changes~~2024 inoperating ~~leverage~~profit inmargin ~~the~~comparisons ~~segment’s~~were ~~operational~~favorably ~~and~~impacted ~~administrative cost structure - 45 basis points~~by:

•~~The~~Higher ~~impact~~third ofquarter a2025 ~~product~~core ~~line~~sales ~~disposition~~and ~~which~~improvements ~~did~~in ~~not~~leverage ~~qualify~~in asthe ~~discontinued~~segment’s ~~operations~~operational and administrative cost structure, net of the impact of product mix - 15170 basis points

Operating profit margin decreased 230 basis points during the six-month period ended June 27, 2025 as compared to the comparable period of 2024. The following factors unfavorably impacted year-over-year operating profit margin:34

~~•The~~Table ~~impact~~ of ~~product mix, changes in leverage in the segment’s operational and administrative cost structure, currency exchange rates and lower sales - 215 basis points~~Contents

~~•The~~Third ~~impact~~quarter of2025 avs. ~~product~~third ~~line~~quarter ~~disposition~~2024 ~~which~~operating ~~did~~profit ~~not~~margin ~~qualify~~comparisons aswere ~~discontinued~~unfavorably ~~operations~~impacted ~~- 15 basis points~~by:

•Third quarter 2025 impairment charge related to a trade name - 60 basis points

•Third quarter 2025 impact of a product line disposition which did not qualify as discontinued operations - 10 basis points

Operating profit margin decreased 120 basis points during the nine-month period ended September 26, 2025 as compared to the comparable period of 2024. The following factors unfavorably impacted year-over-year operating profit margin:

•The impact of product mix and currency exchange rates, net of higher 2025 core sales and improvements in leverage from the segment’s operational and administrative cost structure - 85 basis points

•First nine months of 2025 impairment charge related to a trade name - 20 basis points

•First nine months of 2025 impact of a product line disposition which did not qualify as discontinued operations - 15 basis points

COST OF SALES AND GROSS PROFIT

	Three-Month Period Ended						~~Six~~Nine-Month Period Ended
($ in millions)	~~June~~September 2726, 2025			~~June~~September 2827, 2024			~~June~~September 2726, 2025			~~June~~September 2827, 2024
Sales	$	56,~~936~~053		$	5,~~743~~798		$	1117,~~677~~730		$	1117,~~539~~337
Cost of sales	(2,~~413~~530)			(2,~~315~~397)			(47,~~643~~173)			(47,~~624~~021)
Gross profit	$	3,523		$	3,~~428~~401		$	710,~~034~~557		$	610,~~915~~316
Gross profit margin	5958.32		%	5958.7		%	6059.25		%	59.95		%

Cost of sales increased year-over-year during both the three and ~~six~~nine-month periods ended ~~June~~September 2726, 2025 as compared to the comparable periods in 2024. The increase during ~~the~~both ~~three-month~~periods ~~period~~ was primarily due to the impact of higher year-over-year sales volumes, currency exchange rates and product mix. The increase during the ~~six~~nine-month period ~~was~~also ~~primarily~~reflected ~~due to the impact of higher year-over-year sales volumes, currency exchange rates, product mix and~~ a $15 million impairment charge related to a facility in the Biotechnology segment ~~recorded in the first half of 2025~~. These increases were partially offset by a $25 million acquisition-related charge associated with the fair value adjustment to inventory recorded in the first ~~half~~nine months of 2024 in connection with the acquisition of Abcam plc.

Year-over-year gross profit margin decreased during the three-month period ended ~~June~~September 2726, 2025 as compared to the comparable period in 2024 primarily due to product mix, the impact of currency exchange rates, ~~product mix~~ and tariff costs, partially offset by the impact of continued productivity improvement initiatives and higher year-over-year sales volumes. Year-over-year gross profit margin ~~increased~~remained consistent in the ~~six~~nine-month period ended ~~June~~September 2726, 2025 ~~primarily~~as ~~due~~compared to the ~~impact~~comparable ofprior ~~product~~year ~~mix~~period ~~and~~as higher year-over-year sales volumes, ~~partially~~and the impact of product mix were offset by the impact of currency exchange rates and tariff costs. ~~The~~Gross ~~increase~~margin iswas also ~~due~~impacted toby the ~~impact of an~~ acquisition-related charge recorded in the first ~~half~~nine months of 2024, net of the facility impairment recorded in the first ~~half~~nine months of 2025, both referenced above.

OPERATING EXPENSES

	Three-Month Period Ended						~~Six~~Nine-Month Period Ended
($ in millions)	~~June~~September 2726, 2025			~~June~~September 2827, 2024			~~June~~September 2726, 2025			~~June~~September 2827, 2024
Sales	$	56,~~936~~053		$	5,~~743~~798		$	1117,~~677~~730		$	1117,~~539~~337
Selling, general and administrative expenses	21,~~360~~991			12,~~869~~060			46,~~218~~209			35,~~676~~736
Research and development expenses	~~403~~378			~~391~~383			~~782~~1,160			~~759~~1,142
SG&A as a % of sales	3932.89		%	3235.5		%	3635.10		%	3133.91		%
R&D as a % of sales	6.82		%	6.86		%	6.75		%	6.6		%

32SG&A expenses as a percentage of sales decreased year-over-year during the three-month period ended September 26, 2025 and increased year-over-year during the nine-month period ended September 26, 2025 as compared to the comparable periods in 2024. The decrease during the three-month period was primarily due to the $222 million impairment charge recorded in the third quarter of 2024, partially offset by the $101 million of impairment charges incurred in the third quarter of 2025. To a lesser extent, the decrease was driven by incremental year-over-year cost savings associated with continuing productivity improvement initiatives and cost structure improvements, net of a year-over-year increase in costs incurred for productivity improvement actions. The increase in SG&A as a percentage of sales during the nine-month period ended September 26, 2025 was primarily driven by the $548 million of impairment charges recorded in the first nine months of 2025, partially offset by the $222 million impairment charge recorded in the third

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~~SG&A~~quarter ~~expenses~~of as2024. To a ~~percentage~~lesser ~~of sales increased during both the three and six-month periods ended June 27~~extent, ~~2025 as compared to~~ the ~~comparable~~increase ~~periods~~was ~~in 2024, primarily~~ driven by ~~the $432 million impairment charge related to~~ a ~~trade name in the Life Sciences segment recorded in the second quarter of 2025, and to a lesser extent, a~~ year-over-year increase in costs incurred for productivity improvement actions, net of incremental year-over-year cost savings associated with continuing productivity improvement initiatives and cost structure improvements. Refer to Note 8 to the accompanying Consolidated Condensed Financial Statements for additional information regarding the impairment charges.

R&D expenses (consisting principally of internal and contract engineering personnel costs) as a percentage of sales decreased during the three-month period ended September 26, 2025 and remained essentially flat during ~~both~~ the ~~three and six~~nine-month ~~periods~~period ended ~~June~~September 2726, 2025 as compared to the comparable ~~period~~periods of 2024,. The asdecrease in the three-month period was primarily a result of the timing of spending on new product research and the impact of higher year-over-year sales. In the nine-month period, increased R&D spending correlated to the ~~increases~~increase in sales.

OTHER INCOME (EXPENSE), NET

For a description of the Company’s other income (expense), net during the three and ~~six~~nine-month periods ended ~~June~~September 2726, 2025 and ~~June~~September 2827, 2024, refer to Note 7 to the accompanying Consolidated Condensed Financial Statements.

INTEREST COSTS AND FINANCING

For a discussion of the Company’s outstanding indebtedness, refer to Note 10 to the accompanying Consolidated Condensed Financial Statements.

Interest expense of $7167 million and $~~143~~210 million for the three and ~~six~~nine-month periods ended ~~June~~September 2726, 2025, respectively, was $620 million ~~higher~~lower and $137 million ~~higher~~lower than the comparable periods of 2024, due primarily to ~~the impact of currency exchange rates, partially offset by~~ a lower average interest rate on the Company’s commercial paper borrowings versus the comparable periods of 2024, partially offset by the impact of currency exchange rates.

Interest income of $83 million and $1417 million for the three and ~~six~~nine-month periods ended ~~June~~September 2726, 2025, respectively, was $311 million lower and $8586 million lower than the comparable periods of 2024, due primarily to lower average cash balances in 2025 as a result of share repurchases ~~and acquisitions~~.

INCOME TAXES

The following table summarizes the Company’s effective tax rate:

	Three-Month Period Ended				~~Six~~Nine-Month Period Ended
	June 27, 2025		June 28, 2024		June 27, 2025		June 28, 2024
	September 26, 2025		September 27, 2024		September 26, 2025		September 27, 2024
Effective tax rate	15.36	%	16.3	%	15.45	%	15.36	%

The Company operates globally, including in certain jurisdictions with lower tax rates than the U.S. federal statutory rate. Therefore, the impact of Danaher’s global operations and benefits from tax credits and incentives contributes to a lower effective tax rate compared to the U.S. federal statutory tax rate. For each period presented, the effective tax rate differs from the U.S. federal statutory rate of 21.0% principally due to the impact of the Company’s global operations, research tax credits, foreign-derived intangible income and aggregate net discrete benefits or charges.

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positions. The effective tax rate for this period also included the tax effect from an intangible asset impairment, which reduced the effective tax rate by 0.5%.

The Company (including its subsidiaries) conducts business globally, and files numerous consolidated and separate income tax returns in federal, state and foreign jurisdictions. In addition to the Company’s significant presence in the U.S., the Company also has a significant presence in China, Denmark, Germany, Singapore, Sweden, Switzerland and the United Kingdom. Excluding these jurisdictions, the Company believes that a change in the statutory tax rate of any individual foreign country would not have a material impact on the Company’s financial statements given the geographical dispersion of the Company’s taxable income.

The Company and its subsidiaries are routinely examined by various U.S. and non-U.S. taxing authorities. The IRS has completed substantially all of the examinations of the Company’s federal income tax returns through 2015 and is currently examining certain of the Company’s federal income tax returns for 2016 through 2022. In addition, the Company has subsidiaries in Canada, China, Denmark, France, Germany, India, Italy, Switzerland, the United Kingdom and various other countries, states and provinces that are currently under audit for years ranging from 2004 through 2023.

In the fourth quarter of 2022, the IRS proposed significant adjustments to the Company’s taxable income for the years 2016 through 2018 with respect to the deferral of tax on certain premium income related to the Company’s self-insurance programs. For income tax purposes, the recognition of premium income has been deferred in accordance with U.S. tax laws related to insurance. The proposed adjustments would have increased the Company’s taxable income over the 2016 through 2018 periods by approximately $2.5 billion. In the first quarter of 2023, the Company settled these proposed adjustments with the IRS, although the audit is still open with respect to other matters for the 2016 through 2018 period. The impact of the settlement with respect to the Company’s self-insurance policies was not material to the Company’s financial statements, including cash flows and the effective tax rate. As the settlement with the IRS was specific to the audit period, the settlement does not preclude the IRS from proposing similar adjustments to the Company’s self-insurance programs with respect to periods after 2018. Management believes the positions the Company has taken in its U.S. tax returns are in accordance with the relevant tax laws.

On July 4, 2025, the OBBBA was enacted, which includes permanent extensions of most expiring Tax Cuts and Jobs Act provisions ~~and~~as well as international tax changes. The ~~Company~~application ~~is still evaluating the potential impacts~~ of the OBBBA; ~~however,~~to the Company ~~does~~did not ~~anticipate it will~~ have a material impact on ~~the~~its ~~Company’s~~ financial statements during the three-month period ended September 26, 2025.

The Company expects its effective tax rate for the remainder of 2025 to be approximately 17.0% based on its projected mix of earnings. The Company’s effective tax rate could vary as a result of many factors, including but not limited to the following:

•The expected rate for the remainder of 2025 includes the anticipated discrete income tax benefits from excess tax deductions related to the Company’s stock compensation programs, which are reflected as a reduction in tax expense, though the actual benefits (if any) will depend on the Company’s stock price and stock option exercise patterns.

•The actual mix of earnings by jurisdiction could fluctuate from the Company’s projection.

•The tax effects of other discrete items, including accruals related to tax contingencies, the resolution of worldwide tax matters, tax audit settlements, statute of limitations expirations and changes in tax regulations.

•Any additional future changes in tax law or the implementation of increases in tax rates, the impact of future regulations and any related additional tax planning efforts to address these changes.

As a result of the uncertainty in predicting these items, it is reasonably possible that the actual effective tax rate used for financial reporting purposes will change in future periods compared to the estimate above.

Refer to Note 6 to the accompanying Consolidated Condensed Financial Statements for discussion regarding the Company’s significant tax matters.

COMPREHENSIVE INCOME

Comprehensive income ~~increased~~decreased by approximately $~~538~~1.2 ~~million~~billion and increased by approximately $31.08 billion for the three and ~~six~~nine-month periods ended ~~June~~September 2726, 2025, respectively, as compared to the comparable periods of 2024. For the three-month period ended ~~June~~September 2726, 2025, the ~~increase~~decrease in comprehensive income was primarily driven by ~~increased~~decreased gains from foreign currency translation adjustments, partially offset by ~~lower~~higher net earnings. For the ~~six~~nine-month period ended ~~June~~September 2726, 2025, the increase in comprehensive income was primarily driven by increased gains from foreign currency translation adjustments and, to a lesser extent, gains on cash flow hedges, partially offset by lower net earnings. The Company recorded foreign currency translation ~~gains~~losses of ~~approximately~~ $~~1.0~~71 ~~billion and $121~~ million ~~for the three-month periods ended June 27, 2025~~ and ~~June 28, 2024, respectively. The Company recorded foreign currency translation~~ gains of approximately $21.52 billion for the ~~six~~three-month ~~period~~periods ended ~~June~~September 2726, 2025 ~~compared~~and ~~to losses of $827 million for the six-month period ended June~~September 2827, 2024, respectively. The ~~foreign~~Company ~~currency translation gains in the three and six-month periods ended June 27, 2025 were primarily~~

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recorded foreign currency translation gains of approximately $2.4 billion and $389 million for the nine-month periods ended September 26, 2025 and September 27, 2024, respectively. The foreign currency translation losses in the three-month period ended September 26, 2025 were primarily driven by the change in the exchange rates between the U.S. dollar, Swedish krona and the British pound, while the ~~euro~~gains ~~and~~in the nine-month period ended September 26, 2025 were primarily driven by the change in the exchange rates between the U.S. dollar, Swedish krona, the British pound and the euro. Foreign currency translation adjustments reflect the gain or loss resulting from the impact of the change in currency exchange rates on the Company’s foreign operations as they are translated to the Company’s reporting currency, the U.S. dollar. The Company recorded gains of $1348 million and $~~169~~217 million from cash flow hedge adjustments related to the Company’s cross-currency swap derivative contracts for the three and ~~six~~nine-month periods ended ~~June~~September 2726, 2025, respectively, as compared to gains of $3063 million and ~~losses~~ of $2043 million for the comparable periods of 2024.

LIQUIDITY AND CAPITAL RESOURCES

Management assesses the Company’s liquidity in terms of its ability to generate cash to fund its operating, investing and financing activities. The Company continues to generate substantial cash from operating activities and believes that its operating cash flow, cash on hand and other sources of liquidity will be sufficient to allow it to continue investing in existing businesses (including capital expenditures), consummating strategic acquisitions and investments, paying interest and servicing debt, paying dividends and funding restructuring activities, as well as to repurchase common stock when deemed appropriate and manage its capital structure on a short-term and long-term basis.

The Company has relied primarily on borrowings under its commercial paper program to address liquidity requirements that exceed the capacity provided by its operating cash flows and cash on hand, while also accessing the capital markets from time to time including to secure financing for more significant acquisitions or to take advantage of favorable interest rate environments or other market conditions. Subject to any limitations that may result from market disruptions, the Company anticipates following the same approach in the future.

Overview of Cash Flows and Liquidity

Following is an overview of the Company’s cash flows and liquidity ($ in millions):

	Six-Month Period Ended
	Nine-Month Period Ended
	June 27, 2025		June 28, 2024
	September 26, 2025		September 27, 2024
Net cash provided by operating activities	$	24,~~637~~299	$	34,~~156~~669
Cash paid for acquisitions	$	—	$	(12525)
Payments for additions to property, plant and equipment	(~~493~~785)		(~~578~~876)
Proceeds from sales of property, plant and equipment	10		112
Payments for purchases of investments	(5079)		(~~127~~188)
Proceeds from sales of investments	1012		9251
Proceeds from sale of product line	9		—
All other investing activities	1421		2639
Total cash used in investing activities	$	(~~500~~812)	$	(~~681~~1,287)
Proceeds from the issuance of common stock in connection with stock-based compensation, net	$	1439	$	76143
Payment of dividends	(~~423~~652)		(~~377~~573)
Net borrowings (maturities longer than 90 days)	4		—
Net proceeds from borrowings (maturities of 90 days or less)	22		1
Net (repayments of) proceeds from borrowings (maturities of 90 days or less)	(1)		15
Borrowings (maturities longer than 90 days)	4		—
Net repayments of borrowings (maturities longer than 90 days)	—		(974)
Repayments of borrowings (maturities longer than 90 days)	(500)		(974)
Payments for repurchase of common stock	(13,~~078~~088)		(45,~~530~~170)
All other financing activities	(18108)		(58120)
Total cash used in financing activities	$	(14,~~502~~283)	$	(56,~~848~~693)

As of ~~June~~September 2726, 2025, the Company held approximately $31.05 billion of cash and cash equivalents.

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Operating Activities

Cash flows from operating activities can fluctuate significantly from period-to-period as working capital needs and the timing of payments for income taxes, restructuring activities and productivity improvement initiatives and other items impact reported cash flows.

35Operating cash flows were approximately $4.3 billion for the first nine months of 2025, a decrease of $370 million, or 8%, as compared to the comparable period of 2024. The year-over-year change in operating cash flows from 2024 to 2025 was primarily attributable to the following factors:

~~Table~~•2025 operating cash flows reflected a decrease of ~~Contents~~$396 million in net earnings for the first nine months of 2025 as compared to the comparable period in 2024.

~~Operating~~•Net ~~cash~~earnings ~~flows were approximately $2.6 billion~~ for the first ~~six~~nine months of 2025, aalso ~~decrease~~included of $519 million, orhigher ~~16%~~year-over-year noncash charges primarily for impairments, as ~~compared~~well toas ~~the~~for ~~comparable~~unrealized ~~period~~investment gains/losses, intangible asset amortization, depreciation and stock compensation expense, net of ~~2024. The~~a year-over-year ~~change~~decrease in amortization of an acquisition-related inventory step-up and a 2025 pretax gain on the sale of a product line. Depreciation expense relates to the Company’s manufacturing and operating facilities as well as instrumentation leased to customers under OTL arrangements. Depreciation, amortization, impairments and stock compensation are noncash expenses that decrease earnings without a corresponding impact to operating cash flows. Unrealized investment gains/losses impact net earnings without immediately impacting cash flows as the cash flow impact from ~~2024~~investments tooccurs ~~2025~~when ~~was~~the ~~primarily~~invested ~~attributable~~capital is returned to the ~~following factors:~~Company.

•~~2025~~The ~~operating~~aggregate ~~cash~~of ~~flows~~trade ~~reflected~~accounts areceivable, ~~decrease~~inventories ofand trade accounts payable used $~~486~~441 million in ~~net~~operating ~~earnings~~cash ~~for~~flows during the first ~~six~~nine months of 2025, as compared to $179 million of operating cash flows provided in the comparable period inof 2024. The amount of cash flow generated from or used by the aggregate of trade accounts receivable, inventories and trade accounts payable depends upon how effectively the Company manages the cash conversion cycle, which effectively represents the number of days that elapse from the day it pays for the purchase of raw materials and components to the collection of cash from its customers and can be significantly impacted by the timing of collections and payments in a period.

•~~Net~~The ~~earnings~~aggregate ~~for the first six months~~ of ~~2025~~prepaid ~~also~~expenses ~~included~~and ~~$492~~other ~~million higher year-over-year noncash charges primarily for impairments~~assets, asdeferred ~~well~~income astaxes ~~for~~and ~~unrealized~~accrued ~~investment~~expenses ~~gains/losses, intangible asset amortization, depreciation~~ and ~~stock~~other ~~compensation~~liabilities ~~expense,~~used ~~net~~$424 ofmillion ~~a year-over-year decrease in amortization~~ of anoperating ~~acquisition-related~~cash ~~inventory~~flows ~~step-up~~during ~~and~~the afirst ~~2025~~nine ~~pretax~~months ~~gain on the sale~~ of a2025, ~~product~~compared ~~line. Depreciation expense relates~~ to ~~the~~$551 ~~Company’s~~million ~~manufacturing~~of ~~and~~ operating ~~facilities~~cash asflows ~~well~~used asin ~~instrumentation~~the ~~leased~~comparable toperiod ~~customers~~of ~~under OTL arrangements~~2024. ~~Depreciation,~~The ~~amortization,~~timing ~~impairments~~of ~~and~~cash ~~stock~~income ~~compensation~~tax ~~are~~payments ~~noncash~~and ~~expenses~~customer ~~that~~funding, ~~decrease earnings without a corresponding impact to operating cash flows. Unrealized investment gains/losses impact~~ net ~~earnings~~of ~~without~~normal ~~immediately~~operations ~~impacting~~drove ~~cash flows as~~ the ~~cash~~majority ~~flow~~of ~~impact~~this ~~from investments occurs when the invested capital is returned to the Company~~change.

•The aggregate of trade accounts receivable, inventories and trade accounts payable used $225 million in operating cash flows during the first six months of 2025, compared to $334 million of operating cash flows provided in the comparable period of 2024. The amount of cash flow generated from or used by the aggregate of trade accounts receivable, inventories and trade accounts payable depends upon how effectively the Company manages the cash conversion cycle, which effectively represents the number of days that elapse from the day it pays for the purchase of raw materials and components to the collection of cash from its customers and can be significantly impacted by the timing of collections and payments in a period.

•The aggregate of prepaid expenses and other assets, deferred income taxes and accrued expenses and other liabilities used $573 million of operating cash flows during the first six months of 2025, compared to $607 million of operating cash flows used in the comparable period of 2024. The timing of cash income tax payments and customer funding, net of normal operations drove the majority of this change.

Investing Activities

Cash flows relating to investing activities consist primarily of cash used for acquisitions and capital expenditures, including instruments leased to customers, cash used for investments and cash proceeds from divestitures of businesses or assets.

Net cash used in investing activities decreased $~~181~~475 million in the ~~six~~nine-month period ended ~~June~~September 2726, 2025 compared to the comparable period of 2024, primarily as a result of a decrease in cash paid for acquisitions, purchases of investments and capital expenditures, ~~and~~partially ~~cash~~offset ~~used~~by ~~for~~lower ~~purchases~~proceeds from the sales of investments. In addition, during the ~~six~~nine-month periods ended ~~June~~September 2726, 2025 and ~~June~~September 2827, 2024 the Company invested $5079 million and $~~127~~188 million, respectively, in non-marketable equity securities and partnerships.

Though the relative significance of particular categories of capital investment can change from period to period, capital expenditures are typically made for ~~increasing manufacturing capacity,~~ the manufacture of instruments that are used in OTL arrangements that certain of the Company’s businesses enter into with customers, increasing manufacturing capacity, replacing equipment, purchasing facilities, supporting new product development and improving IT systems. Capital expenditures decreased $8591 million on a year-over-year basis for the ~~six~~nine-month period ended ~~June~~September 2726, 2025 compared to the comparable period in 2024.

Financing Activities and Indebtedness

Cash flows relating to financing activities can consist of cash flows associated with the issuance and repayments of commercial paper, issuance and repayment of long-term debt, borrowings under committed credit facilities, issuance and repurchases of common stock, issuance of preferred stock and payments of cash dividends to shareholders. Financing activities used cash of approximately $14.53 billion during the ~~six~~nine-month period ended ~~June~~September 2726, 2025 compared to approximately $56.87 billion of cash used in the comparable period of 2024. The year-over-year decrease in cash used in financing activities was primarily due to lower repurchases of the Company’s common stock in the 2025 period compared to 2024 and alower ~~repayment~~repayments of long-term borrowings in 2025 compared to 2024, partially offset by lower proceeds from the issuance of common stock in connection with stock-based compensation ~~in the 2025 period compared to 2024~~ and higher dividend payments year-over-year.

For a description of the Company’s outstanding debt as of June 27, 2025 and the Company’s commercial paper programs and credit facility, refer to Note 10 to the accompanying Consolidated Condensed Financial Statements. As of June 27, 2025, the Company was in compliance with all of its respective debt covenants. 39

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On October 10, 2025, DH Switzerland Finance S.a.r.l., a wholly-owned finance subsidiary of the Company, completed an underwritten offering of Swiss franc-denominated bonds and received net proceeds from the issuance, after underwriting discounts and commissions and offering expenses, of approximately CHF 1.2 billion (approximately $1.6 billion based on currency exchange rates as of the date of the pricing of the Swiss Bonds). For a description of the Company’s outstanding debt as of September 26, 2025, long-term debt repayments, the Swiss Bond issuance and the Company’s commercial paper programs and credit facility, refer to Note 10 to the accompanying Consolidated Condensed Financial Statements. As of September 26, 2025, the Company was in compliance with all of its respective debt covenants.

Stock Repurchase Program

For information regarding the Company’s stock repurchase program and repurchases of common stock, refer to Part II—Item 2, “Unregistered Sales of Equity Securities and Use of Proceeds”.

Dividends

Aggregate cash payments for dividends on Company common stock during the ~~six~~nine-month period ended ~~June~~September 2726, 2025 were $~~423~~652 million compared to $~~377~~573 million for the ~~six~~nine-month period ended ~~June~~September 2827, 2024. The increase in dividend payments on the Company’s common stock compared to the comparable period of 2024 is due to the ~~increase~~increases in the quarterly dividend rate for common stock beginning with respect to the dividends paid in the second ~~quarter~~quarters of each of 2024 and 2025, partially offset by lower average common stock outstanding.

In the ~~second~~third quarter of 2025, the Company declared a regular quarterly dividend of $0.32 per share of Company common stock payable on ~~July~~October 2531, 2025 to holders of record as of ~~June~~September 2726, 2025.

Cash and Cash Requirements

As of ~~June~~September 2726, 2025, the Company held approximately $31.05 billion of cash and cash equivalents that were held on deposit with financial institutions or invested in highly liquid investment-grade debt instruments with a maturity of 90 days or less. Of the cash and cash equivalents, $~~306~~207 million was held within the U.S. and approximately $21.73 billion was held outside of the U.S. The Company will continue to have cash requirements to support general corporate purposes, which may include working capital needs, capital expenditures, acquisitions and investments, paying interest and servicing debt, paying taxes and any related interest or penalties, funding its restructuring activities and pension plans as required, paying dividends to shareholders, repurchasing shares of the Company’s common stock and supporting other business needs.

The Company generally intends to use available cash and internally generated funds to meet these cash requirements, but in the event that additional liquidity is required, the Company may also borrow under its commercial paper programs (if available) or borrow under the Company’s Credit Facility, enter into new credit facilities and either borrow directly thereunder or use such credit facilities to backstop additional borrowing capacity under its commercial paper programs (if available) and/or access the capital markets (if available). The Company also may from time to time seek to access the capital markets to take advantage of favorable interest rate environments or other market conditions. With respect to the commercial paper and any other notes scheduled to mature during the next twelve months, the Company expects to repay the principal amounts when due using available cash, proceeds from new issuances of commercial paper (if available), drawing on its Credit Facility and/or proceeds from other debt issuances. Refer to Note 10 to the accompanying Consolidated Condensed Financial Statements for additional information regarding the classification of commercial paper and other notes scheduled to mature during the next twelve months.

While repatriation of some cash held outside the U.S. may be restricted by local laws, most of the Company’s foreign cash could be repatriated to the U.S. Following enactment of the Tax Cuts and Jobs Act and the associated Transition Tax, in general, repatriation of cash to the U.S. can be completed with no incremental U.S. tax; however, repatriation of cash could subject the Company to non-U.S. taxes on distributions. The cash that the Company’s non-U.S. subsidiaries hold for indefinite reinvestment is generally used to finance foreign operations and investments, including acquisitions. The income taxes, if any, that would be applicable to the repatriation of such earnings (including basis differences in our foreign subsidiaries) are not readily determinable. As of ~~June~~September 2726, 2025, management believes that it has sufficient sources of liquidity to satisfy its cash needs, including its cash needs in the U.S.

CRITICAL ACCOUNTING ESTIMATES

The Company is supplementing the critical accounting estimates as described in the 2024 Annual Report with the following critical accounting estimate. There have been no other material changes to the Company’s critical accounting estimates as described in the 2024 Annual Report.

Acquired intangibles - The Company reviews identified intangible assets for impairment whenever events or changes in circumstances indicate that the related carrying amounts may not be recoverable. Determining whether an impairment loss occurred for finite-lived intangibles requires a comparison of the carrying amount of the asset group to the sum of undiscounted cash flows expected to be generated by the asset group. These analyses require management to make judgments and estimates about future revenues, expenses, market conditions and discount rates related to these assets. Indefinite-lived intangibles are subject to impairment testing at least annually or more frequently if events or changes in circumstances indicate that potential impairment exists. Determining whether an impairment loss occurred for indefinite-lived intangible assets involves calculating the fair value of the indefinite-lived intangible assets and comparing the fair value to their carrying value. In addition, the Company reviews the useful lives for intangible assets and whether events or changes in circumstances indicate that an indefinite life may no longer be appropriate. If the fair value is less than the carrying value, the difference is recorded as an impairment loss. If actual results are not consistent with management’s

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judgments and estimates about future revenues, expenses, market conditions and discount rates related to these assets. Indefinite-lived intangibles are subject to impairment testing at least annually or more frequently if events or changes in circumstances indicate that potential impairment exists. Determining whether an impairment loss occurred for indefinite-lived intangible assets involves calculating the fair value of the indefinite-lived intangible assets and comparing the fair value to their carrying value. In addition, the Company reviews the useful lives for intangible assets and whether events or changes in circumstances indicate that an indefinite life may no longer be appropriate. If the fair value is less than the carrying value, the difference is recorded as an impairment loss. If actual results are not consistent with management’s estimates and assumptions, goodwill and other intangible assets may be overstated, and a charge would need to be taken against net earnings which would adversely affect the Company’s financial statements.

The Company estimates the fair value of acquired trade names through the use of a relief from royalty method, which values an indefinite-lived intangible asset by estimating the royalties saved through the ownership of an asset. Under this method, an owner of an indefinite-lived intangible asset determines the arm’s length royalty that likely would have been charged if the owner had to license the asset from a third-party. The royalty rate, which is based on the estimated rate applied against forecasted sales, is tax-effected and discounted to present value using a discount rate commensurate with the relative risk of achieving the cash flow attributable to the asset. Management judgment is necessary to determine key assumptions, including revenue growth rates, perpetual revenue growth rates, royalty rates and discount rates. As further described in Note 8 to the accompanying Consolidated Condensed Financial Statements, in connection with the decision to reorganize and integrate certain genomics consumables businesses in the Life Sciences operating segment, the Company recorded a noncash impairment charge of $432 million pretax ($328 million after-tax) for the ~~three and six~~nine-~~months~~month period ended ~~June~~September 2726, 2025 related to a trade name. The charge is included in ~~selling,~~SG&A ~~general~~expenses ~~and administrative expense~~ in the accompanying Consolidated Condensed ~~Statements~~Statement of Earnings. Following this impact, if the fair value of the trade name declined by 10%, the Company estimates it would record an additional impairment charge of $8 million.

Goodwill is evaluated for impairment on a reporting unit basis. Reporting units resulting from recent acquisitions generally present the highest risk of impairment. Management believes the impairment risk associated with these reporting units generally decreases as these businesses are integrated into the Company and better positioned for potential future earnings growth. The Company’s reorganization and integration of certain businesses in the Life Sciences operating segment at the beginning of the third quarter of 2025, as described in the previous paragraph, changed two of its five goodwill reporting units and triggered a goodwill impairment analysis. InThe ~~the third quarter of 2025, the~~ Company performed goodwill impairment analyses prior to, and after, the change in reporting units and in both instances, the fair values of the Company’s reporting units exceeded their carrying values and consequently did not result in an impairment charge. In the test of the prior reporting units, the excess of the estimated fair value over carrying value (expressed as a percentage of carrying value for the respective reporting unit) for each of the previous reporting units as of the testing date ranged from approximately 30% to approximately 365%. The excess of the estimated fair value over carrying value for each of the Company’s current reporting units as of the testing date ranged from approximately 40% to approximately 365%. The decrease in the excess of the estimated fair value over carrying value from the Company’s 2024 annual goodwill impairment test to the third quarter 2025 tests reflect the 2025 business performance and the current trading multiples for companies operating in businesses similar to the Company’s reporting units (used within the market approach to estimate fair value under the goodwill impairment test). To evaluate the sensitivity of the fair value calculations used in both goodwill impairment tests, the Company applied a hypothetical 10% decrease to the fair values of each of the reporting units and compared those hypothetical values to the reporting unit carrying values. Based on this hypothetical 10% decrease, the excess of the estimated fair value over carrying value for each of the Company’s current reporting units ranged from approximately 30% to approximately 315%.

ITEM 3. QUANTITATIVE AND QUALITATIVE DISCLOSURES ABOUT MARKET RISK

Quantitative and qualitative disclosures about market risk appear in “Management’s Discussion and Analysis of Financial Condition and Results of Operations—Financial Instruments and Risk Management,” in the Company’s 2024 Annual Report.

ITEM 4. CONTROLS AND PROCEDURES

The Company’s management, with the participation of the Company’s President and Chief Executive Officer, and Executive Vice President and Chief Financial Officer, has evaluated the effectiveness of the Company’s disclosure controls and procedures (as such term is defined in Rules 13a-15(e) and 15d-15(e) under the Securities Exchange Act of 1934, as amended (the “Exchange Act”)) as of the end of the period covered by this report. Based on such evaluation, the Company’s President and Chief Executive Officer, and Executive Vice President and Chief Financial Officer, have concluded that, as of the end of such period, the Company’s disclosure controls and procedures were effective.

There have been no changes in the Company’s internal control over financial reporting (as such term is defined in Rules 13a-15(f) and 15d-15(f) under the Exchange Act) that occurred during the Company’s most recent completed fiscal quarter that have materially affected, or are reasonably likely to materially affect, the Company’s internal control over financial reporting.

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PART II - OTHER INFORMATION

ITEM 1. LEGAL PROCEEDINGS

For ~~additional~~ information regarding legal proceedings, refer to Note 12 in the accompanying Consolidated Condensed Financial Statements and to “Management’s Discussion and Analysis of Financial Condition and Results of Operations—-Legal Proceedings” in the Company’s 2024 Annual Report.

Consistent with SEC Regulation S-K Item 103, the Company has elected to disclose those environmental proceedings (if any) with a governmental entity as a party where the Company reasonably believes such proceeding would result in monetary sanctions, exclusive of interest and costs, of $1 million or more.

ITEM 1A. RISK FACTORS

The Company is supplementing the risk factors previously disclosed in the Company's 2024 Annual Report with the following risk factor. Additional information regarding risk factors can be found in “Management’s Discussion and Analysis of Financial Condition and Results of Operations—Information Related to Forward-Looking Statements,” in Part I—Item 2 of this Report and in Part I—Item 1A of Danaher’s 2024 Annual Report.

Significant developments or changes in national laws or policies to protect or promote domestic interests and/or address foreign competition can have an adverse effect on our business and financial statements.

Significant developments or changes in national laws or policies to protect or promote domestic interests and/or address foreign competition, including laws and policies in areas such as trade, manufacturing, government purchasing, healthcare, intellectual property, regulatory enforcement and investment/development, can adversely affect our business and financial statements. The U.S. has announced and/or implemented significant new tariffs on imports from a wide range of countries, which has prompted retaliatory tariffs by a number of countries and a cycle of retaliatory tariffs by both the U.S. and other countries. Subsequently, actions have been taken by the U.S. and certain other countries to modify certain of these tariffs and/or delay their effective dates,; ~~but~~the asU.S. has entered into trade agreements with certain countries implementing new tariffs; and in August 2025 the U.S. Court of ~~July~~Appeals for the Federal Circuit ruled that certain of the U.S. tariffs that have been implemented are contrary to law (though such ruling has been appealed by the U.S. administration and the U.S. Supreme Court has agreed to hear the case). As of October 2120, 2025, a number of new tariffs remain in effect, including significant tariffs and export restrictions between the U.S. and China. Collectively, these tariffs increase the cost to us of supplies and components we import, which in turn has required and will require us to implement surcharges and/or increase the price of certain of our products, among other countermeasures; can increase the cost to our customers of certain of our finished goods, which together with the surcharges and price increases noted above can adversely impact demand for our products and our competitive positioning; could adversely impact the availability to us of certain products in certain countries and disrupt our supply chains, with related impacts to our operations; and could exacerbate inflation, diminish investment and result in broader negative impacts, economic instability and capital markets dislocation that may adversely impact demand for our products. In addition, whenever we are unable to fully recover higher costs, or whenever there is a time delay between the increase in costs and our ability to recover these costs, our margins and profitability ~~can~~are ~~decline~~adversely affected. The delayed tariffs may take effect, the U.S. Supreme Court may overrule all or part of the ruling by the U.S. Court of Appeals for the Federal Circuit, the U.S. may implement additional tariffs and other measures, further retaliatory tariffs and other retaliatory actions may follow and the risks and adverse effects noted above may increase. Please see “Management’s Discussion and Analysis of Financial Condition and Results of Operations” for further discussion of the impact of these tariffs. Though the risks identified above in certain cases have already adversely impacted ~~part~~parts of our business, the full impact of these tariffs and other actions on the Company and on our business partners remains highly uncertain and subject to rapid change.

In addition, certain governments have implemented policies to induce “re-shoring” of supply chains, reduce reliance on imported supplies and promote national production. For example, the Chinese government has issued a series of policies in the past several years to promote the development and use of local medical devices.

All of the risks identified in this risk factor can adversely affect our business and financial statements.

~~ITEM 2. UNREGISTERED SALES OF EQUITY SECURITIES AND USE OF PROCEEDS~~42

Neither the Company nor any “affiliated purchaser” repurchased any shares of Company common stock during the three-month period ended June 27, 2025. On July 22, 2024, the Company’s Board of Directors approved a repurchase program (the “Repurchase Program”) authorizing the repurchase of up to 20 million shares of the Company’s common stock from time to time on the open market or in privately negotiated transactions. As of June 27, 2025, approximately 12 million shares remained available for repurchase pursuant to the Repurchase Program. There is no expiration date for the Repurchase Program, and the timing and amount of any shares repurchased under the program will be determined by members of the Company’s management based on its evaluation of market conditions and other factors. The Repurchase Program may be suspended or discontinued at any time. Any repurchased shares will be available for use in connection with the Company’s equity compensation plans (or any successor plans) and for other corporate purposes. The Company expects to fund any future stock repurchases using the Company’s available cash balances or proceeds from the issuance of debt.

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ITEM 2. UNREGISTERED SALES OF EQUITY SECURITIES AND USE OF PROCEEDS

Issuer Purchases of Equity Securities

For an overview of the Company’s share repurchase programs, refer to Note 13 in the accompanying Consolidated Condensed Financial Statements.

The following table presents a summary of share repurchases made during the quarter ended September 26, 2025 (all share repurchases were made under the 2024 Repurchase Program):


Period	Total Number of Shares Purchased	Average Price Paid Per Share(a)		Total Number of Shares Purchased as Part of Publicly Announced Plans or Programs	Maximum Number of Shares that May Yet Be Purchased Under the Plans or Programs
June 28, 2025 - July 25, 2025	1,007,000	$	202.75	1,007,000	10,993,000
July 26, 2025 - August 22, 2025	8,868,511	200.68		8,868,511	2,124,489
August 23, 2025 - September 26, 2025	124,489	209.81		124,489	37,000,000
Total	10,000,000	$	201.00	10,000,000	37,000,000	(b)

(a) Amounts exclude excise taxes and other transaction costs.

(b) Includes 35,000,000 shares under the 2025 Repurchase Program and 2,000,000 under the 2024 Repurchase Program, authorized by the Company’s Board of Directors on September 9, 2025 and July 22, 2024, respectively.

ITEM 5. OTHER INFORMATION

Director and Officer Trading Arrangements

OnNone ~~May~~of ~~30,~~our ~~2025,~~directors ~~Rainer~~or M.executive ~~Blair,~~officers ~~Danaher’s~~adopted ~~President~~or ~~and~~terminated ~~Chief~~a ~~Executive~~Rule ~~Officer,~~10b5-1 ~~adopted a~~ trading ~~plan~~arrangement ~~that~~or isa ~~intended to satisfy the affirmative defense conditions of Securities Exchange Act~~ non-Rule 10b5-1~~(c)~~ ~~for~~trading ~~the~~arrangement ~~sale~~(as ~~through~~defined ~~May~~in ~~29,~~Item ~~2026~~408(c) of upRegulation toS-K) ~~60,015~~during ~~shares of Danaher common stock pursuant to~~ the ~~exercise~~quarterly ofperiod ~~stock~~covered ~~options~~by ~~otherwise~~this ~~scheduled to expire in February 2027~~report.

Except as described above, none of our directors or executive officers adopted or terminated a Rule 10b5-1 trading arrangement or a non-Rule 10b5-1 trading arrangement (as defined in Item 408(c) of Regulation S-K) during the quarterly period covered by this report.43

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ITEM 6. EXHIBITS

(a)Exhibits:

3.1			Restated Certificate of Incorporation of Danaher Corporation (incorporated by reference from Exhibit 3.1 to Danaher Corporation’s Quarterly Report on Form 10-Q for the quarter ended June 29, 2012)
3.2			Amended and Restated By-laws of Danaher Corporation (incorporated by reference from Exhibit 3.1 to Danaher Corporation’s Current Report on Form 8-K filed ~~December~~September 710, ~~2022~~2025)
10.1			Letter Agreement by and between Danaher Corporation and Matthew Gugino dated July 21, 2025 (incorporated by reference from Exhibit 10.1 to Danaher Corporation’s Current Report on Form 8-K filed July 24, 2025)*
10.2			Agreement Regarding Competition and Protection of Proprietary Interests by and between Danaher Corporation and Matthew Gugino dated July 21, 2025 (incorporated by reference from Exhibit 10.2 to Danaher Corporation’s Current Report on Form 8-K filed July 24, 2025)*
22.1			Subsidiary guarantors and issuers of guaranteed securities and affiliates whose securities collateralize securities of the Registrant
31.1			Certification of Chief Executive Officer Pursuant to Item 601(b)(31) of Regulation S-K, As Adopted Pursuant to Section 302 of the Sarbanes-Oxley Act of 2002
31.2			Certification of Chief Financial Officer Pursuant to Item 601(b)(31) of Regulation S-K, As Adopted Pursuant to Section 302 of the Sarbanes-Oxley Act of 2002
32.1			Certification of Chief Executive Officer, Pursuant to 18 U.S.C. Section 1350, As Adopted Pursuant to Section 906 of the Sarbanes-Oxley Act of 2002
32.2			Certification of Chief Financial Officer, Pursuant to 18 U.S.C. Section 1350, As Adopted Pursuant to Section 906 of the Sarbanes-Oxley Act of 2002
101.INS			Inline XBRL Instance Document - the instance document does not appear in the Interactive Data File because its XBRL tags are embedded within the Inline XBRL document.
101.SCH			Inline XBRL Taxonomy Extension Schema Document
101.CAL			Inline XBRL Taxonomy Extension Calculation Linkbase Document
101.DEF			Inline XBRL Taxonomy Extension Definition Linkbase Document
101.LAB			Inline XBRL Taxonomy Extension Label Linkbase Document
101.PRE			Inline XBRL Taxonomy Extension Presentation Linkbase Document
104			Cover Page Interactive Data File (formatted as inline XBRL and contained in Exhibit 101)

41* Indicates management contract or compensatory plan, contract or arrangement.

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SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized.

		DANAHER CORPORATION
Date:	~~July~~October 2120, 2025	By:	/s/ Matthew R. McGrew
			Matthew R. McGrew
			Executive Vice President and Chief Financial Officer
Date:	~~July~~October 2120, 2025	By:	/s/ Christopher M. Bouda
			Christopher M. Bouda
			Vice President and Chief Accounting Officer

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