? Check this box if no longer

subject to Section 16. Form 4

or Form 5 obligations may continue.

See Instruction 1(b).

U.S. SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding

Company Act of 1935 or Section 30(f) of the Investment Company Act of 1940

1. Name and Address of

Reporting Person*

Seward, James R.

2. Issuer Name and Ticker or Trading Symbol

LabOne, Inc. (LABS)

6. Relationship of Reporting Person to

Issuer (Check all applicable)

_X__Director 10% Owner

(Last) (First) (Middle)

4915 W. 79^th St.

3. IRS or Social Security

Number of Reporting

Person (Voluntary)

4. Statement for

Month/Year

September 2001

__Officer __ Other

(give title below) (specify below)

(Street)

Prairie Village, KS. 66208

5. If Amendment, Date of

Original (Month/Year

7. Individual or Joint/Group Filing

(Check applicable line)

X
Form filed by One Reporting

Person

___ Form filed by More than One

Reporting Person

(City) (State) (Zip)

Table 1 - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned.

1. Title of Security

(Instr. 3)

2. Trans-

action

date:

(Month/

Day/

Year)

3. Trans-

action

Code

(Instr. 8)

4. Securities Acquired (A)

or Disposed of (D)

(Instr. 3, 4 and 5)

5. Amount of

Securities

Beneficially

Owned at

End of Mth.

(Instr. 3

and 4)

6. Ownership

Form:

Direct

(D) or

Indirect

(I)

(Instr. 4)

7. Nature of

Indirect

Beneficial

Ownership

(Instr. 4)

Code

Amount

(A) or

(D)

Price

Common Stock
05/25/2001
A
V
329
A

Common Stock
09/28/2001
M

25,000
A
6.125
41,135
D

* If the Form is filed by more than one Reporting Person, see instruction 4(b)(v).

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. (Print or Type Responses) PAGE 1 OF 2 PAGES

FORM 4 (continued) Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)

1. Title of

Derivative

Security

(Inst. 3)

2. Conver-

sion or

Exercise

Price of

Deriv-

Ative

Security

3. Trans-

action

Date

(Month/

Day/

Year)

4. Transac-

tion Code

(Instr. 8)

5. Number of

Derivative

Securities

Acquired (A)

or Disposed

of (D) (Instr.

3, 4, and 5)

6. Date Exercisable and

Expiration Date

(Month/Day/Year)

7. Title and Amount

of Underlying

Securities (Instr. 3

and 4)

8. Price of

Derivative

Security

Instr. 5)

9. Number

of Deriv-

ative

Securities

Beneficially

Owned at

End of

Month

(Instr. 4)

10. Owner-

ship

Form of

Deriv-

Ative

Security;

Direct

(D) or

Indirect

(I)

(Instr.

11. Nature

of In-

direct

Bene-

ficial

Owner-

ship

(Instr. 4)

Code

(A)

(D)

Date

Exer-

Cisable

Expira-

tion Date

Consultant Stock Option Plan; Right to Buy

6.125

09/28/2001

25,000

04/06/2000

01/06/2010

Common Stock .01 par value per share

25,000

Director Stock Option Plan; Right to Buy

7.60

05/25/2001

6,579

05/25/2004 (1)

05/25/2011

Common Stock .01 par value per share

6,579

6,579

(1) The option vests in three equal annual installments beginning on May 25, 2002.

** Intentional misstatements or omissions of facts constitute Federal Criminal Violations

See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

/s/

James R. Seward 10-09-2001

James R. Seward

by attorney-in-fact Randy Shelton Date

Note: File three copies of this Form, one of which must be manually signed.

If space provided is insufficient, see Instruction 6 for procedure.

PAGE 2 OF 2 PAGES

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SEWARD JAMES R 4