BERTHELSEN SPENCER R 4

4 · IONIS PHARMACEUTICALS INC · Filed Jul 17, 2026

AI-generated summary of this filing

Updated Jul 17, 2026

Ionis (IONS) Director Spencer Berthelsen Receives 5,220 Shares

What Happened

Spencer R. Berthelsen, a director of Ionis Pharmaceuticals (IONS), had 5,220 Restricted Stock Units (RSUs vest and convert) on July 15, 2026, resulting in the acquisition of 5,220 shares of Ionis common stock. The Form 4 reports the shares acquired at $0.00 per share (total $0) and shows a simultaneous conversion/disposition of a derivative instrument for the same 5,220 units (transaction code M = exercise/conversion). This is the delivery of compensation (vested RSUs), not an open‑market purchase or sale.

Key Details

Transaction date: 2026-07-15 (reported on Form 4 filed 2026-07-17 — timely filing)
Reported transaction(s): 5,220 shares acquired via RSU vesting (Exercise/Conversion, code M) at $0.00; 5,220 derivative units disposed at $0.00
Shares owned after transaction: not specified in this filing
Relevant footnotes:
- F1: Shares acquired pursuant to vesting and release of an RSU award.
- F3: Each RSU represents a contingent right to one share (or equivalent cash value).
- F4: RSUs vest 100% on the first anniversary of grant or the next annual meeting, and are delivered on the July 15 following vesting; settlement may be in shares or cash as determined by the company.
- F2: Reporting person disclaims beneficial ownership of securities held by his daughter.
No explicit tax withholding, sale of shares for cash, or 10b5-1 plan indicated in this filing.

Context

This transaction reflects the vesting and settlement of compensation (RSUs) rather than a market buy or sell decision; such vesting events are routine for insiders and do not, by themselves, signal a change in insider sentiment. The use of transaction code M indicates conversion/exercise of a derivative right (the RSU) into common stock.

Form 4

Period: 2026-07-15

Director

Transactions

Exercise/Conversion
Common Stock
[F1]
2026-07-15+5,220→ 161,233 total
Exercise/Conversion
Restricted Stock Unit
[F3][F4]
2026-07-15−5,220→ 2,301 total
Exercise: $0.00→ Common Stock (5,220 underlying)

Holdings

Footnotes (4)

[F1]Acquired pursuant to vesting and release of shares in accordance with a Restricted Stock Unit award.
[F2]The reporting person disclaims beneficial ownership of all securities held by his daughter, and this report should not be deemed an admission that the reporting person is the beneficial owner of such securities for purposes of Section 16 or for any other purpose.
[F3]Each Restricted Stock Unit represents a contingent right to receive one share of Ionis common stock, or its equivalent cash value.
[F4]Restricted Stock Units vest 100% on either the first anniversary of the date of grant or the next regularly scheduled annual meeting of stockholders of the Company, whichever occurs earlier, and are delivered to the reporting person on the July 15th following the vesting date. Upon vesting, the Restricted Stock Units will be paid in whole shares of Ionis common stock or cash as may be determined by the Company.

Signature

By: Patrick R. O'Neil, attorney-in-fact For: Spencer R. Berthelsen|2026-07-17

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