4 1 a86306f4e4.txt FORM 4 ------ U.S. SECURITIES AND EXCHANGE COMMISSION ------------------------------ FORM 4 WASHINGTON, D.C. 20549 OMB APPROVAL ------ ------------------------------ STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OMB Number: 3235-0287 [ ] Check this box if no Expires: January 31, 2005 longer subject to Filed pursuant to Section 16(a) of the Securities Estimated average burden Section 16. Form 4 Exchange Act of 1934, Section 17(a) of the hours per response.........0.5 or Form 5 obligations Public Utility Holding Company Act of 1935 ------------------------------ may continue. See or Section 30(f) of the Investment Company Instruction 1(b). Act of 1940 (Print or Type Responses) ------------------------------------------------------------------------------------------------------------------------------------ 1. Name and Address of Reporting Person* 2. Issuer Name and Ticker or Trading Symbol 6. Relationship of Reporting Person(s) Invitrogen Corporation InforMax, Inc.(INMX) to Issuer (check all applicable) -------------------------------------------- ---------------------------------------------- Director X 10% Owner (Last) (First) (Middle) 3. IRS or Social Security 4. Statement for ---- --- 1600 Faraday Avenue Number of Reporting Month/Year Officer Other (specify -------------------------------------------- Person (Voluntary) December 2, 2002 ---- --- below) (Street) ------------------- (give title below) Carlsbad CA 93008 5. If Amendment, -------------------------------------------- Date of Original ------------------------------------ (City) (State) (Zip) (Month/Year) 7. Individual or Joint/Group Filing ------------------- (check applicable line) Form filed by One ---- Reporting Person X Form filed by More Than ---- One Reporting Person ------------------------------------------------------------------------------------------------------------------------------------ TABLE I -- NON-DERIVATIVE SECURITIES ACQUIRED, DISPOSED OF, OR BENEFICIALLY OWNED ------------------------------------------------------------------------------------------------------------------------------------ 1. Title of Security 2. Trans- 2A. Deemed 3. Trans- 4. Securities Acquired (A) 5. Amount of 6. Ownership 7. Nature of (Instr. 3) action Execution action or Disposed of (D) Securities Form: Indirect Date Date, if any Code (Instr. 3, 4 and 5) Beneficially Direct Beneficial (Instr. 8) Owned at (D) or Ownership (Month/ (Month/ End of Month Indirect (Instr. 4) Day/ Day/ --------------------------------------- (Instr. 3 and 4) (I) Year) Year) Code V Amount (A) or Price (Instr. 4) (D) ------------------------------------------------------------------------------------------------------------------------------------ Common Stock 12/2/02(1) P 55,616(1) A $1.36(1) ------------------------------------------------------------------------------------------------------------------------------------ Common Stock 12/3/02(1) P 52,521(1) A $1.36(1) 24,986,823(1) (I)(1) ------------------------------------------------------------------------------------------------------------------------------------ ------------------------------------------------------------------------------------------------------------------------------------ ------------------------------------------------------------------------------------------------------------------------------------ ------------------------------------------------------------------------------------------------------------------------------------ ------------------------------------------------------------------------------------------------------------------------------------ ------------------------------------------------------------------------------------------------------------------------------------ Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. *If the form is filed by more than one reporting person, see Instruction 4(b)(v). PERSONS WHO ARE TO RESPOND TO THE COLLECTION OF INFORMATION CONTAINED IN THIS FORM ARE NOT REQUIRED (Over) TO RESPOND UNLESS THE FORM DISPLAYS A CURRENTLY VALID OMB CONTROL NUMBER. SEC 1474 (09/02)

Joint Filer Information Name: Babcock, Inc. Address: c/o Invitrogen Corporation 1600 Faraday Avenue Carlsbad, CA 92008 Designated Filer: Invitrogen Corporation Issuer & Ticker Symbol: InforMax, Inc. (INMX) Date of Event Requiring Statement: 12/2/02 Signature: /s/ John Cottingham

INFORMAX INC 4