4 1 a86306z4e4.txt FORM 4 ------ UNITED STATES SECURITIES AND EXCHANGE COMMISSION ------------------------------ FORM 4 WASHINGTON, D.C. 20549 OMB APPROVAL ------ ------------------------------ STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OMB Number: 3235-0287 [ ] Check this box if no Expires: January 31, 2005 longer subject to Filed pursuant to Section 16(a) of the Securities Estimated average burden Section 16. Form 4 Exchange Act of 1934, Section 17(a) of the hours per response.........0.5 or Form 5 obligations Public Utility Holding Company Act of 1935 ------------------------------ may continue. See or Section 30(f) of the Investment Company Instruction 1(b). Act of 1940 (Print or Type Responses) ------------------------------------------------------------------------------------------------------------------------------------ 1. Name and Address of Reporting Person* 2. Issuer Name and Ticker or Trading Symbol 6. Relationship of Reporting Person(s) to Issuer (Check all applicable) Invitrogen Corporation InforMax, Inc. (INMX) Director X 10% Owner --------------------------------------------- ---------------------------------------------- ---- --- (Last) (First) (Middle) 3. I.R.S. Identification 4. Statement for Officer (give Other (Specify Number of Reporting Month/Day/Year ---- title --- below) 1600 Faraday Avenue Person, if an entity below) --------------------------------------------- (Voluntary) December 4, 2002 (Street) ------------------- -------------------------------- -------------------------- Carlsbad CA 92008 5. If Amendment, 7. Individual or Joint/Group Filing --------------------------------------------- Date of Original (Check applicable line) (City) (State) (Zip) (Month/Day/Year) Form filed by one ---- Reporting Person X Form filed by more than ------------------ ---- one Reporting Person ------------------------------------------------------------------------------------------------------------------------------------ TABLE I -- NON-DERIVATIVE SECURITIES ACQUIRED, DISPOSED OF, OR BENEFICIALLY OWNED ------------------------------------------------------------------------------------------------------------------------------------ 1. Title of Security 2. Trans- 2A. 3. Transac- 4. Securities Acquired (A) 5. Amount of 6. Owner- 7. Nature of (Instr. 3) action Deemed tion or Disposed of (D) Securities ship Indirect Date Execution Code (Instr. 3, 4 and 5) Beneficially Form: Beneficial Date, if (Instr. 8) Owned Direct Ownership (Month/ any --------------------------------------- Following (D) or Day/ (Month/ (A) Reported Indirect Year) Day/ Code V Amount or Price Transaction(s) (I) Year) (D) (Instr. 3 and 4) (Instr. 4) (Instr. 4) ------------------------------------------------------------------------------------------------------------------------------------ Common Stock 12/4/02(1) P 1,613,127(1) A $1.36(1) I(1) ------------------------------------------------------------------------------------------------------------------------------------ Common Stock 12/5/02(1) P 1,252,116(1) A $1.36(1) 27,852,066(1) I(1) ------------------------------------------------------------------------------------------------------------------------------------ ------------------------------------------------------------------------------------------------------------------------------------ ------------------------------------------------------------------------------------------------------------------------------------ ------------------------------------------------------------------------------------------------------------------------------------ ------------------------------------------------------------------------------------------------------------------------------------ ------------------------------------------------------------------------------------------------------------------------------------ ------------------------------------------------------------------------------------------------------------------------------------ ------------------------------------------------------------------------------------------------------------------------------------ ------------------------------------------------------------------------------------------------------------------------------------ Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. *If the Form is filed by more than one Reporting Person, see Instruction 4(b)(v). (Over) PERSONS WHO RESPOND TO THE COLLECTION OF INFORMATION CONTAINED in this form are not required to respond unless the form displays SEC 1474 (9-02) a currently valid OMB control number.

Joint Filer Information Name: Babcock, Inc. Address: c/o Invitrogen Corporation 1600 Faraday Avenue Carlsbad, CA 92008 Designated Filer: Invitrogen Corporation Issuer & Ticker Symbol: InforMax, Inc. (INMX) Date of Event Requiring Statement: 12/4/02 Signature: /s/ John Cottingham ---------------------------------

INFORMAX INC 4