OMB APPROVAL

OMB Number: 3235-0287

Expires: January 31, 2005

Estimated average burden
hours per response...0.5

UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, DC 20549

FORM 4

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934,
Section 17(a) of the Public Utility Holding Company Act of 1935
or Section 30(h) of the Investment Company Act of 1940

o	Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b)

Name and Address of Reporting
Person* (Last, First, Middle)

Issuer Name and Ticker or
Trading Symbol

I.R.S. Identification Number of Reporting
Person, if an entity (Voluntary)

Norman, M.D., Ruskin

ILEX Oncology, Inc. (ILXO)

c/o ILEX Oncology, Inc.
4545 Horizon Hill Blvd.

Statement for (Month/Day/Year)

If Amendment, Date of Original (Month/Day/Year)

12/4/02

(Street)

Relationship of Reporting Person(s) to Issuer (Check All Applicable)

Individual or Joint/Group Filing
(Check Applicable Line)

San Antonio, TX 78229

(City) (State) (Zip)

Director

10% Owner

Form filed by One Reporting Person

Officer (give title below)

Form filed by More than One Reporting Person

Other (specify below)

Reminder:		Report on a separate line for each class of securities beneficially owned directly or indirectly.

*		If the form is filed by more than one reporting person, see instruction 4(b)(v).

Table I — Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned

Title of Security
(Instr. 3)

Transaction Date
(Month/Day/Year)

2a.

Deemed Execution
Date, if any.
(Month/Day/Year)

Transaction Code
(Instr. 8)

Securities Acquired (A)
or Disposed of (D)
(Instr. 3, 4 and 5)

Amount of Securities
Beneficially Owned
Following Reported
Transactions(s)
(Instr. 3 and 4)

Ownership
Form:
Direct (D) or
Indirect (I)
(Instr. 4)

Nature of
Indirect
Beneficial
Ownership
(Instr. 4)

Code

Amount

(A)
or
(D)

Price

Common Stock

13,909

Common Stock

1,000

(1)

Page 2

Table II — Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)

Title of Derivative
Security
(Instr. 3)

Conversion or Exercise
Price of Derivative
Security

Transaction
Date
(Month/Day/Year)

3a.

Deemed Execution
Date, if any
(Month/Day/Year)

Transaction
Code
(Instr. 8)

Number of Derivative Securities
Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)

Code

(A)

(D)

Option to Buy

$7.01

Common Stock Warrants (right to buy)

$8.76

Option to Buy

$8.625

Option to Buy

$28.00

Option to Buy

$25.89

Option to Buy

$9.44

12/4/02

6,000

Page 3

Table II — Derivative Securities Acquired, Disposed of, or Beneficially Owned — Continued
(e.g., puts, calls, warrants, options, convertible securities)

Date Exercisable and
Expiration Date
(Month/Day/Year)

Title and Amount
of Underlying Securities
(Instr. 3 and 4)

Price of Derivative
Security
(Instr. 5)

Number of Derivative
Securities Beneficially Owned
Following Reported Transaction(s)
(Instr. 4)

10.

Ownership Form of
Derivative Security:
Direct (D) or Indirect (I)
(Instr. 4)

11.

Nature of
Indirect
Beneficial
Ownership
(Instr. 4)

Date
Exercisable

Expiration
Date

Title

Amount or
Number of
Shares

(2)

Common Stock

7,128

7/22/96

7/22/01

Common Stock

1,159

(3)

Common Stock

5,000

11/30/00

11/30/10

Common Stock

5,000

12/17/01

12/17/11

Common Stock

6,000

12/4/02

12/4/12

Common Stock

6,000

Explanation of Responses:

(1) Shares owned by the reporting person's spouse.

(2) Options were granted on 10/18/96 pursuant to the 1996 Non-Employee Director Stock Option Plan ("NEDSOP") to buy 17,128 shares of Common Stock exercisable in increments of 357 shares on 11/30/96 and the last day of each succeeding month. (Previously reported.)

(3) Options were granted on 2/25/98 pursuant to the 1996 NEDSOP to buy 5,000 shares of Common Stock exercisable in increments of 104.167 shares on 3/31/98 and the last day of each succeeding month until 2/28/02. (Previously reported.)

/s/ MARK MELLIN*		1/16/03
**Signature of Reporting Person		Date

*		Attorney-In-Fact for Ruskin Norman, M.D.
**		Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

Note:		File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.

Page 4

NORMAN RUSKIN C 4