~~Table~~SECURITIES ofAND ~~Contents~~EXCHANGE COMMISSION

~~SECURITIES~~Washington, ~~AND~~D.C. ~~EXCHANGE COMMISSION~~20549

~~Washington,~~FORM ~~D.C. 20549~~8-K

~~FORM~~CURRENT ~~8-K~~REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

~~CURRENT~~Date ~~REPORT Pursuant~~of toreport ~~Section 13 or 15~~(d)Date of ~~the~~ ~~Securities~~earliest ~~Exchange~~event ~~Act~~reported): ofMay 12, ~~1934~~ 2009

~~Date~~ ofEPIX ~~report (Date of earliest event reported): May 11~~Pharmaceuticals, ~~2009~~Inc.

(Exact ~~EPIX~~Name ~~Pharmaceuticals,~~of ~~Inc.~~ Registrant as Specified in its Charter)

~~(Exact Name of Registrant as Specified in its Charter)~~Delaware

~~Delaware~~ (State or Other Jurisdiction of Incorporation)

000-21863		04-3030815
(Commission File Number)		(IRS Employer Identification No.)

4 Maguire Road, Lexington, Massachusetts		02421
(Address of Principal Executive Offices)		(Zip Code)

Registrant’s telephone number, including area code: (781) 761-7600

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions (see General Instruction A.2. below):

o Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425) o Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12) o Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b)) o Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

~~o Soliciting~~Item ~~material~~3.01 ~~pursuant~~Notice of Delisting or Failure to ~~Rule 14a-12~~Satisfy ~~under~~a ~~the~~Continued ~~Exchange~~Listing ~~Act~~Rule ~~(17~~or ~~CFR~~Standard; ~~240~~Transfer of Listing.~~14a-12)~~

~~o Pre-commencement~~ On ~~communications~~May 12, ~~pursuant~~2009, toEPIX ~~Rule 14d-2~~Pharmaceuticals, Inc. (bthe “Company”) ~~under~~received ~~the~~notification ~~Exchange~~from ~~Act~~The NASDAQ Stock Market LLC (17“NASDAQ”) stating that the Company’s common stock would be delisted from ~~CFR~~The ~~240~~NASDAQ Capital Market effective at the open of the market on May 14, 2009.~~14d-2~~ The delisting of the Company’s common stock is a result of the Company’s failure to comply with NASDAQ Marketplace Rule 5550(b)) by evidencing a $35 million market value of listed shares for its common stock for 10 consecutive trading days or by regaining compliance with one of the alternative listing criteria, including a shareholders’ equity of at least $2.5 million.

~~o Pre-commencement~~Item 7.01 ~~communications pursuant to Rule~~Regulation ~~13e-4(c)~~FD ~~under the Exchange Act (17 CFR 240~~Disclosure.~~13e-4(c))~~

~~TABLE~~ On OFMay 13, ~~CONTENTS~~2009, the Company issued a press release, a copy of which is being furnished as Exhibit 99.1 to this Current Report on Form 8-K.

	Item 2.02 Results of Operations and Financial Condition.
	Item 9.01 Financial Statements and Exhibits.
SIGNATURES
EXHIBIT INDEX
EX-99.1 Press release issued by EPIX Pharmaceuticals, Inc. on May 11, 2009

The information in this Item 7.01 and Exhibit 99.1 attached hereto is intended to be furnished and shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934 (the “Exchange Act”) or otherwise subject to the liabilities of that section, nor shall it be deemed incorporated by reference in any filing under the Securities Act of 1933 or the Exchange Act, except as expressly set forth by specific reference in such filing.

~~Table~~Item 9.01 ofFinancial ~~Contents~~Statements and Exhibits.

~~Item 2.02~~(d) ~~Results of Operations and Financial Condition.~~ Exhibits:

~~On May 11, 2009, EPIX Pharmaceuticals, Inc~~99.1 ~~announced~~Press ~~certain~~Release ~~financial~~issued ~~results~~by ~~for~~ the ~~quarter~~ ~~ended~~registrant ~~March 31~~on May 13, 2009. ~~A copy of the press release is being furnished as Exhibit 99.1 to this Report on Form 8-K.~~

~~The information in this Report on Form 8-K and Exhibit 99.1 attached hereto is intended to be~~SIGNATURES furnished and shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934 (the “Exchange Act”) or otherwise subject to the liabilities of that section, nor shall it be deemed incorporated by reference in any filing under the Securities Act of 1933 or the Exchange Act, except as expressly set forth by specific reference in such filing.

~~Item 9.01~~ Pursuant ~~Financial~~to ~~Statements~~the ~~and~~requirements ~~Exhibits~~of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

(d) Exhibits:


	EPIX PHARMACEUTICALS, INC.
May 13, 2009	By:	/s/ Kim Cobleigh Drapkin
	Kim Cobleigh Drapkin
	Chief Financial Officer

~~99.1~~EXHIBIT ~~Press Release issued by the registrant on May 11, 2009, furnished~~INDEX ~~herewith.~~


Exhibit Number		Description

99.1		Press Release issued by the registrant on May 13, 2009.

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

	EPIX PHARMACEUTICALS, INC.
May 11, 2009	By:	/s/ Kim Cobleigh Drapkin
		Kim Cobleigh Drapkin
		Chief Financial Officer

EXHIBIT INDEX

Exhibit Number		Description
99.1		Press Release issued by the registrant on May 11, 2009, furnished herewith.

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