U.S. SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 4 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(f) of the Investment Company Act of 1940 |_| Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b). ================================================================================ 1. Name and Address of Reporting Person* Biscount Overseas Ltd. -------------------------------------------------------------------------------- (Last) (First) (Middle) c/o J. Owadyeh, 3 Freilagr St. -------------------------------------------------------------------------------- (Street) Zurich Switzerland CH 8043 -------------------------------------------------------------------------------- (City) (State) (Zip) ================================================================================ 2. Issuer Name and Ticker or Trading Symbol Saliva Diagnostic Systems, Inc. (SALVE OB) ================================================================================ 3. IRS Identification Number of Reporting Person, if an Entity (Voluntary) ================================================================================ 4. Statement for Month/Year August, 2000 ================================================================================ 5. If Amendment, Date of Original (Month/Year) ================================================================================ 6. Relationship of Reporting Person to Issuer (Check all applicable) |_| Director |x| 10% Owner |_| Officer (give title below) |_| Other (specify below) ================================================================================ 7. Individual or Joint/Group Filing (Check Applicable Line) |x| Form filed by one Reporting Person |_| Form filed by more than one Reporting Person ================================================================================ * If the Form is filed by more than one Reporting Person, see Instruction 4(b)(v). ================================================================================ Table I -- Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned ================================================================================

6. 4. 5. Owner- Securities Acquired (A) or Amount of ship 3. Disposed of (D) Securities Form: 7. Transaction (Instr. 3, 4 and 5) Beneficially Direct Nature of 2. Code ---------------------------- Owned at End (D) or Indirect 1. Transaction (Instr. 8) (A) of Month Indirect Beneficial Title of Security Date ------------ Amount or Price (Instr. 3 (I) Ownership (Instr. 3) (mm/dd/yy) Code V (D) and 4) (Instr.4) (Instr. 4) ------------------------------------------------------------------------------------------------------------------------------------ Common Stock Par Value $.01 0508/01/00 S 1052,000 D $0.~~380~~218 98,~~843~~992,822 D ------------------------------------------------------------------------------------------------------------------------------------ Common Stock Par Value $.01 0508/0503/00 S 2033,~~000~~400 D $0.~~313~~198 98,~~843~~992,822 D ------------------------------------------------------------------------------------------------------------------------------------ Common Stock Par Value $.01 0508/08/00 S 575,000 D $0.~~281~~288 98,~~843~~992,822 D ------------------------------------------------------------------------------------------------------------------------------------ Common Stock Par Value $.01 ~~05/~~08/~~00 S 20,000 D $0.290 9,843,822 D ------------------------------------------------------------------------------------------------------------------------------------ Common Stock Par Value $.01 05~~17/~~09/~~00 S 5,000 D $0.250 9,843,822 D ------------------------------------------------------------------------------------------------------------------------------------ Common Stock Par Value $.01 05/09/00 S 5,000 D $0.260 9,843,822 D ------------------------------------------------------------------------------------------------------------------------------------ Common Stock Par Value $.01 05/10~~/00 S 10~~,000 D $0.~~250~~425 98,~~843~~992,822 D ------------------------------------------------------------------------------------------------------------------------------------ Common Stock Par Value $.01 0508/1018/00 S 5120,000 D $0.~~250~~387 98,~~843~~992,822 D ------------------------------------------------------------------------------------------------------------------------------------ Common Stock Par Value $.01 0508/1018/00 S 5,000 D $0.255 9,843,822 D ------------------------------------------------------------------------------------------------------------------------------------ Common Stock Par Value $.01 05/11/00 S 27,216 D $0.250 9,843,822 D ------------------------------------------------------------------------------------------------------------------------------------ Common Stock Par Value $.01 05/11/00 S 10,000 D $0.~~250~~403 98,~~843~~992,822 D ------------------------------------------------------------------------------------------------------------------------------------ Common Stock Par Value $.01 0508/1221/00 S 3526,~~000~~300 D $0.~~250~~377 98,~~843~~992,822 D ------------------------------------------------------------------------------------------------------------------------------------ Common Stock Par Value $.01 0508/12/00 S 10,000 D $0.240 9,843,822 D ------------------------------------------------------------------------------------------------------------------------------------ Common Stock Par Value $.01 05/12/00 S 25,000 D $0.240 9,843,822 D ------------------------------------------------------------------------------------------------------------------------------------ Common Stock Par Value $.01 05/12/00 S 15,000 D $0.240 9,843,822 D ------------------------------------------------------------------------------------------------------------------------------------ Common Stock Par Value $.01 05/15/00 S 20,000 D $0.245 9,843,822 D ------------------------------------------------------------------------------------------------------------------------------------ Common Stock Par Value $.01 05/15/00 S 10,000 D $0.245 9,843,822 D ------------------------------------------------------------------------------------------------------------------------------------ Common Stock Par Value $.01 05/15/00 S 10,000 D $0.245 9,843,822 D ------------------------------------------------------------------------------------------------------------------------------------ Common Stock Par Value $.01 05/15/00 S 10,000 D $0.245 9,843,822 D ------------------------------------------------------------------------------------------------------------------------------------ Common Stock Par Value $.01 05/15/00 S 40,000 D $0.245 9,843,822 D ------------------------------------------------------------------------------------------------------------------------------------ Common Stock Par Value $.01 05/15/00 S 10,000 D $0.260 9,843,822 D ------------------------------------------------------------------------------------------------------------------------------------ Common Stock Par Value $.01 05/16/00 S 25,000 D $0.250 9,843,822 D ------------------------------------------------------------------------------------------------------------------------------------ Common Stock Par Value $.01 05/16/00 S 50,000 D $0.245 9,843,822 D ------------------------------------------------------------------------------------------------------------------------------------ Common Stock Par Value $.01 05/16/00 S 100,000 D $0.245 9,843,822 D ------------------------------------------------------------------------------------------------------------------------------------ Common Stock Par Value $.01 05/16/00 S 101,500 D $0.248 9,843,822 D ------------------------------------------------------------------------------------------------------------------------------------ Common Stock Par Value $.01 05/17/00 S 73,500 D $0.250 9,843,822 D ------------------------------------------------------------------------------------------------------------------------------------ Common Stock Par Value $.01 05/17/00 S 60,000 D $0.240 9,843,822 D ------------------------------------------------------------------------------------------------------------------------------------ Common Stock Par Value $.01 05/17/00 S 50,000 D $0.240 9,843,822 D ------------------------------------------------------------------------------------------------------------------------------------ Common Stock Par Value $.01 05/22/00 S ~~16,000 D $0.195 9,843,822 D ------------------------------------------------------------------------------------------------------------------------------------ Common Stock Par Value $.01 05/18/00 S~~ 15,000 D $0.~~230~~313 98,~~843~~992,822 D ------------------------------------------------------------------------------------------------------------------------------------ Common Stock Par Value $.01 0508/19/00 S 5,000 D $0.230 9,843,822 D ------------------------------------------------------------------------------------------------------------------------------------ Common Stock Par Value $.01 05/19/00 S 15,000 D $0.198 9,843,822 D ------------------------------------------------------------------------------------------------------------------------------------ Common Stock Par Value $.01 05/22/00 S 1610,000 D $0.~~195~~317 98,~~843~~992,822 D ------------------------------------------------------------------------------------------------------------------------------------ Common Stock Par Value $.01 0508/2223/00 S 532,~~000~~300 D $0.~~200~~292 98,~~843~~992,822 D ------------------------------------------------------------------------------------------------------------------------------------ Common Stock Par Value $.01 05/22/00 S 9,000 D $0.195 9,843,822 D ------------------------------------------------------------------------------------------------------------------------------------ Common Stock Par Value $.01 05/31/00 S 9,000 D $0.210 9,843,822 D ------------------------------------------------------------------------------------------------------------------------------------ Common Stock Par Value $.01 05/19/00 S 9,000 D $0.198 9,843,822 D ====================================================================================================================================

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. Page 1 of 2 FORM 4 (continued) Table II -- Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities) ================================================================================

9. 10. Number Owner- of ship 2. Deriv- Form of Conver- 5. 7. ative Deriv- 11. sion Number of Title and Amount Secur- ative Nature of Derivative 6. of Underlying 8. ities Secur- of Exer- 4. Securities Date Securities Price Bene- ity: In- cise 3. Trans- Acquired (A) Exercisable and (Instr. 3 and 4) of ficially Direct direct Price Trans- action or Disposed Expiration Date ---------------- Deriv- Owned (D) or Bene- 1. of action Code of(D) (Month/Day/Year) Amount ative at End In- ficial Title of Deriv- Date (Instr. (Instr. 3, ---------------- or Secur- of direct Owner- Derivative ative (Month/ 8) 4 and 5) Date Expira- Number ity Month (I) ship Security Secur- Day/ ------ ------------ Exer- tion of (Instr. (Instr. (Instr. (Instr. (Instr. 3) ity Year) Code V (A) (D) cisable Date Title Shares 5) 4) 4) 4) ------------------------------------------------------------------------------------------------------------------------------------ N/A ------------------------------------------------------------------------------------------------------------------------------------ ------------------------------------------------------------------------------------------------------------------------------------ ------------------------------------------------------------------------------------------------------------------------------------ ------------------------------------------------------------------------------------------------------------------------------------ ------------------------------------------------------------------------------------------------------------------------------------ ------------------------------------------------------------------------------------------------------------------------------------ ------------------------------------------------------------------------------------------------------------------------------------ ------------------------------------------------------------------------------------------------------------------------------------ ~~------------------------------------------------------------------------------------------------------------------------------------~~ ====================================================================================================================================

Explanation of Responses: ** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a). /s/ J. Owadyeh September 27, 2000 --------------------------------------------- ----------------------- ** Signature of Reporting Person Date Note: File three copies of this Form, one of which must be manually signed. If space provided is insufficient, see Instruction 6 for procedure. Page 2 of 2

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