UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

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FORM 6-K

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Report of Foreign Private Issuer

Pursuant to Rule 13a-16 or 15d-16 ~~under~~

under the Securities Exchange Act of 1934

For the ~~quarterly~~month ~~period~~of ~~ended~~December ~~September 30,~~ 2025

Commission File Number 001-38332

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QIAGEN N.V.

(Translation of registrant’s name into English)

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Hulsterweg 82

5912 PL Venlo

The Netherlands

(Address of principal executive office)

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Indicate by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F.:

Form 20-F ý Form 40-F o

Table of Contents

QIAGEN N.V.

Form 6-K

~~TABLE~~Table OFof ~~CONTENTS~~Contents


Item						Page
Other Information						3
Signatures						4
Exhibit Index						5

~~Table~~Other ofInformation ~~Contents~~

~~OTHER~~On ~~INFORMATION~~December 18, 2025, QIAGEN N.V. (NYSE: QGEN; Frankfurt Prime Standard: QIA) issued a press release with details for completion of a synthetic share repurchase plan that combines a direct capital repayment with a reverse stock split. The press release is furnished herewith as Exhibit 99.1 and is incorporated by reference herein.

For the three and nine months ended September 30, 2025, QIAGEN N.V. prepared its quarterly report under United States generally accepted accounting principles (U.S. GAAP). This quarterly report is furnished herewith as Exhibit 99.1 and incorporated by reference herein.

~~Table of Contents~~Signatures

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

QIAGEN N.V. By: /s/ Roland Sackers Roland Sackers Chief Financial Officer


			QIAGEN N.V.

By:			/s/ Roland Sackers
			Roland Sackers
			Chief Financial Officer

Date:			December 19, 2025

Date: November 5, 2025

~~Table~~Exhibit ofIndex ~~Contents~~

EXHIBIT INDEX


Exhibit No.						Exhibit

99.1						Press Release dated December 18, 2025

ExhibitNo.						Exhibit
99.1						U.S. GAAP Quarterly Report for the Period Ended September 30, 2025

Filing Compare · QIAGEN N.V.