UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 4 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP ( ) Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instructions 1(b). 1. Name and Address of Reporting Person Kirincic, Anthony J. c/o Kirlin Holding Corp. 6901 Jericho Turnpike Syosset, NY 11791 USA 2. Issuer Name and Ticker or Trading Symbol Kirlin Holding Corp. KILN 3. IRS or Social Security Number of Reporting Person (Voluntary) 4. Statement for Month/Year May 31, 2001 5. If Amendment, Date of Original (Month/Year) 6. Relationship of Reporting Person(s) to Issuer (Check all applicable) (X) Director (X) 10% Owner (X) Officer (give title below) ( ) Other (specify below) President and Chief Financial Officer 7. Individual or Joint/Group Filing (Check Applicable Line) (X) Form filed by One Reporting Person ( ) Form filed by More than One Reporting Person

___________________________________________________________________________________________________________________________________ Table I -- Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned | ___________________________________________________________________________________________________________________________________| 1. Title of Security |2. |3. |4.Securities Acquired (A) |5.Amount of |6.Dir |7.Nature of Indirect | | Transaction | or Disposed of (D) | Securities |ect | Beneficial Ownership | | | | | Beneficially |(D)or | | | | | | | A/| | Owned at |Indir | | | Date |Code|V| Amount | D | Price | End of Month |ect(I)| | ___________________________________________________________________________________________________________________________________| Common Stock |35/817/030|AP |V |755,000 |A |$1.95 | |D | | |1 | | | | | | | | | -----------------------------------------------------------------------------------------------------------------------------------| Common Stock |~~75,000~~5/18/0|P (| |600 |A |$1).91 | |D |-- | |1 | | | | | | | | | -----------------------------------------------------------------------------------------------------------------------------------| Common Stock |5/18/0|P | |3,400 |A |$2.00 | |8D | | |1 | | | | | | | | | -----------------------------------------------------------------------------------------------------------------------------------| Common Stock |5/21/0|P | |4,000 (|A |$2).15 | |D |-- | |1 | | | | | | | | | -----------------------------------------------------------------------------------------------------------------------------------| Common Stock |5/22/0|P | |600 |A |$2.05 | |~~15,000~~D ~~(3)~~| |D |--1 | | | | | | | | | -----------------------------------------------------------------------------------------------------------------------------------| Common Stock | 5/23/0|P | |6,400 |A |$2.05 |292,~~504~~916,000 |D |-- | |1 | | | | | | | | | -----------------------------------------------------------------------------------------------------------------------------------| ~~Common Stock~~ | | | | | | |3120,~~073~~000 |I |~~By 401~~(K1) | -----------------------------------------------------------------------------------------------------------------------------------| ___________________________________________________________________________________________________________________________________| ___________________________________________________________________________________________________________________________________ Table II -- Derivative Securitites Acquired, Disposed of, or Beneficially Owned | ___________________________________________________________________________________________________________________________________| 1.Title of Derivative |2.Con- |3. |4. |5.Number of De |6.Date Exer|7.Title and Amount |8.Price|9.Number |10.|11.Nature of| Security |version |Transaction | rivative Secu |cisable and| of Underlying |of Deri|of Deriva |Dir|Indirect | |or Exer | | | rities Acqui |Expiration | Securities |vative |tive |ect|Beneficial | |cise | | | red(A) or Dis |Date(Month/| |Secu |Securities |(D)|Ownership | |Price of| | | posed of(D) |Day/Year) | |rity |Benefi |or | | |Deriva- | | | |Date |Expir| | |ficially |Ind| | |tive | | | | A/|Exer-|ation| Title and Number | |Owned at |ire| | |Secu- | | | | | D |cisa-|Date | of Shares | |End of |ct | | |rity |Date |Code|V| Amount | |ble | | | |Month |(I)| | ___________________________________________________________________________________________________________________________________| | | | | | | | | | | | | | | | ___________________________________________________________________________________________________________________________________|

Explanation of Responses: (1) Held in the individual retirement account of reporting person's spouse. (2) Barry Shapiro is signing for Anthony J. Kirincic pursuant to authorization on file. SIGNATURE OF REPORTING PERSON /s/ by Barry Shapiro(2) DATE June 6, 2001

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