UNITED STATES
SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM 8-K

CURRENT REPORT

Pursuant to Section 13 or 15(d) of
The Securities Exchange Act of 1934

Date of Report (Date of earliest event reported): December ~~November 28~~11, 2017

PhaseRx, Inc.

(Exact name of registrant as specified in its charter)

Delaware	001-37772	20-4690620
(State or other jurisdiction of incorporation)	(Commission File Number)	(IRS Employer Identification No.)

410 W. Harrison Street, Suite 300 Seattle, Washington	98119
(Address of principal executive offices)	(Zip Code)

Registrant’s telephone number, including area code: (206) 805-6300

(Former name or former address, if changed since last report)

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

	¨	Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
	¨	Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
	¨	Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
	¨	Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§240.12b-2 of this chapter).

Emerging growth company x

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. x

Item 81.0103. ~~Other~~Bankruptcy ~~Events~~or Receivership.

On ~~November~~December 2811, 2017, PhaseRx, Inc. (the “Company”) ~~issued~~filed a ~~press~~voluntary ~~release~~petition ~~announcing~~under ~~that~~Chapter ~~the~~11 ~~European~~of ~~Medicines~~the ~~Agency’s~~U.S. ~~Committee~~Bankruptcy ~~for~~Code ~~Orphan~~in ~~Medicinal Products~~the ~~issued~~U.S. aBankruptcy ~~positive~~Court ~~opinion recommending orphan medicinal product (orphan drug) designation~~ for ~~PRX-ASL for~~ the ~~treatment of~~District ~~argininosuccinate lyase deficiency. A copy~~ of Delaware ~~this~~(the ~~press~~“Bankruptcy ~~release~~Court”) is(Case ~~attached hereto as Exhibit 99~~No.1 ~~and is incorporated herein by reference~~17-12890).

~~Item~~The 9Company is operating in the ordinary course of business as a "debtor-in-possession" under the jurisdiction of the Bankruptcy Court and in accordance with the applicable provisions of the Bankruptcy Code and orders of the Bankruptcy Court.~~01.~~ ~~Financial~~The ~~Statements~~Company is working with Cowen and ~~Exhibits~~Company to review financial and strategic alternatives.

~~(d)~~On ~~Exhibits~~December 11, 2017, the Company issued a press release announcing commencement of a voluntary Chapter 11 bankruptcy protection proceeding. A copy of this press release is attached hereto as Exhibit 99.1 and is incorporated herein by reference.

Exhibit No.		Description
99.1		Press release, dated November 28, 2017

Item 9.01. Financial Statements and Exhibits.

~~SIGNATURE~~(d) Exhibits.

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

Exhibit No.		Description
99.1		Press release, dated December 11, 2017

	PhaseRx, Inc.
Date: November 28, 2017	By:	/s/ Robert W. Overell
		Robert W. Overell, Ph.D.
		Chief Executive Officer

SIGNATURE

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

	PhaseRx, Inc.

Date: December 12, 2017	By:	/s/ Robert W. Overell
		Robert W. Overell, Ph.D.
		Chief Executive Officer

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