FORM 6-K

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. ~~20549~~20459

Report of Foreign Issuer

Pursuant to Rule 13a - 16 or 15d - 16 of the Securities Exchange Act of 1934

~~December~~January 0215, ~~2003~~2004

Amersham plc

(Translation of registrant's name into English)

Amersham Place Little Chalfont Buckinghamshire HP7 9NA England

Little Chalfont

Buckinghamshire HP7 9NA

England

(Address of principal executive offices)

Indicate by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F

Form 20-F X Form 40-F__

Indicate by check mark whether the registrant by furnishing the information contained in this Form is also thereby furnishing the information to the Commission pursuant to Rule 12g3-2(b) under the Securities Exchange Act of 1934

Yes___ No X

If "Yes" is marked, indicate below the file number assigned to the registrant in
connection with Rule 12g3-2(b): 82-...............

EXHIBIT INDEX

Exhibit No. 1 Holding(s) in Company dated 1012 ~~November~~January ~~2003~~2004 Exhibit No. 2 Holding(s) in Company dated 12 ~~November~~January ~~2003~~2004 Exhibit No. 3 Holding(s) in Company dated 2112 ~~November~~January ~~2003~~2004 Exhibit No. 4 Holding(s) in Company dated 2112 ~~November~~January ~~2003~~2004 Exhibit No. 5 Holding(s) in Company dated 2112 ~~November~~January ~~2003~~2004 Exhibit No. 6 Holding(s) in Company dated 2412 ~~November~~January ~~2003~~2004 Exhibit No. 7 Holding(s) in Company dated 12 January 2004 Exhibit No. 1

Exhibit No. 1

SCHEDULE 10

NOTIFICATION OF MAJOR INTERESTS IN SHARES

1) Name of company Amersham plc 2) Name of shareholder having a major interest ~~The~~ Franklin ~~Capital~~Resources ~~Group Companies~~ Inc and its direct and indirect subsidiaries 3) Please state whether notification indicates that it is in respect of holding of the shareholder named in 2 above or in respect of a non-beneficial interest or in the case of an individual holder if it is a holding of that person's spouse or children under the age of 18 Non Beneficial interest 4) Name of the registered holder(s) and, if more than one holder, the number of shares held by each of them ~~The~~ Franklin ~~Capital~~Resources ~~Group Companies~~ Inc and its direct and indirect subsidiaries 5) Number of shares/amount of stock acquired Not advised 6) Percentage of issued class N/A 7) Number of shares/amount of stock disposed N/A 8) Percentage of issued class N/A 9) Class of security Ordinary shares of 5 pence each 10) Date of transaction ~~Not~~ 10 ~~advised~~December 2003 11) Date company informed 7 12 ~~November~~December 2003 12) Total holding following this notification 26 19,~~025~~938,~~621~~175 Ordinary Shares of 5p each 13) Total percentage holding of issued class following this notification 3 2.~~697~~823% 14) Any additional information ~~N/A~~ The interest of Franklin Resources Inc and its direct and indirect subsidiaries in the share capital of Amersham plc has fallen below 3% and accordingly they no longer have a notifiable interest under ss198-202 of the Companies Act 1985 15) Name of contact and telephone number for queries Susan Henderson, Deputy Company Secretary Tel 01494 542063 16) Name and signature of authorised company official responsible for making this notification Susan M Henderson, Date of notification ~~10th~~23 ~~November~~December 2003 Exhibit No. 2

Exhibit No. 2

SCHEDULE 10

NOTIFICATION OF MAJOR INTERESTS IN SHARES

1) Name of company Amersham plc 2) Name of shareholder having a major interest ~~Merrill~~ Credit ~~Lynch~~Suisse &First CoBoston ~~Inc~~Equities Limited and its direct and indirect subsidiaries 3) Please state whether notification indicates that it is in respect of holding of the shareholder named in 2 above or in respect of a non-beneficial interest or in the case of an individual holder if it is a holding of that person's spouse or children under the age of 18 Non Beneficial interest 4) Name of the registered holder(s) and, if more than one holder, the number of shares held by each of them ~~Merrill~~ Credit ~~Lynch~~Suisse &First CoBoston ~~Inc~~Equities Limited and its direct and indirect subsidiaries 5) Number of shares/amount of stock acquired Not advised 6) Percentage of issued class N/A 7) Number of shares/amount of stock disposed N/A 8) Percentage of issued class N/A 9) Class of security Ordinary shares of 5 pence each 10) Date of transaction ~~Not~~ 11 ~~advised~~December 2003 11) Date company informed 31 16 ~~October~~December 2003 12) Total holding following this notification 27 35,~~844~~927,~~192~~698 Ordinary Shares of 5p each 13) Total percentage holding of issued class following this notification 3 5.~~955~~099% 14) Any additional information N/A 15) Name of contact and telephone number for queries Susan Henderson, Deputy Company Secretary Tel 01494 542063 16) Name and signature of authorised company official responsible for making this notification Susan M Henderson, Date of notification ~~13th~~24 ~~November~~December 2003 Exhibit No. 3

Exhibit No. 3

SCHEDULE 10

NOTIFICATION OF MAJOR INTERESTS IN SHARES

1) Name of company Amersham plc 2) Name of shareholder having a major interest ~~The~~ UBS ~~Capital~~Investment ~~Group Companies Inc and its direct and indirect subsidiaries~~Bank 3) Please state whether notification indicates that it is in respect of holding of the shareholder named in 2 above or in respect of a non-beneficial interest or in the case of an individual holder if it is a holding of that person's spouse or children under the age of 18 ~~Non~~ Beneficial interest 4) Name of the registered holder(s) and, if more than one holder, the number of shares held by each of them ~~The~~ UBS ~~Capital~~Investment ~~Group Companies Inc and its direct and indirect subsidiaries~~Bank 5) Number of shares/amount of stock acquired Not advised 6) Percentage of issued class N/A 7) Number of shares/amount of stock disposed N/A 8) Percentage of issued class N/A 9) Class of security Ordinary shares of 5 pence each 10) Date of transaction ~~Not~~ 16 ~~advised~~December 2003 11) Date company informed 12 22 ~~November~~December 2003 12) Total holding following this notification 21 35,~~044~~893,~~076~~595 Ordinary Shares of 5p each 13) Total percentage holding of issued class following this notification 2 5.~~989~~093% 14) Any additional information ~~The interest of Capital Group Companies Inc and its direct and indirect~~ N/A ~~subsidiaries in the share capital of Amersham plc has fallen below 3% and~~ ~~accordingly they no longer have a notifiable interest under ss198-202 of the Companies Act 1985~~ 15) Name of contact and telephone number for queries Susan Henderson, Deputy Company Secretary Tel 01494 542063 16) Name and signature of authorised company official responsible for making this notification Susan M Henderson, Date of notification 2124 ~~November~~December 2003 Exhibit No. 4

Exhibit No. 4

SCHEDULE 10

NOTIFICATION OF MAJOR INTERESTS IN SHARES

1) Name of company Amersham plc 2) Name of shareholder having a major interest ~~Deutsche~~ Merrill ~~Bank~~Lynch AG& ~~London~~Co Inc and its direct and indirect subsidiaries 3) Please state whether notification indicates that it is in respect of holding of the shareholder named in 2 above or in respect of a non-beneficial interest or in the case of an individual holder if it is a holding of that person's spouse or children under the age of 18 Non -Beneficial interest 4) Name of the registered holder(s) and, if more than one holder, the number of shares held by each of them ~~Deutsche~~ Merrill ~~Bank~~Lynch AG& ~~London~~Co Inc and its direct and indirect subsidiaries 5) Number of shares/amount of stock acquired Not advised 6) Percentage of issued class N/A 7) Number of shares/amount of stock disposed N/A 8) Percentage of issued class N/A 9) Class of security Ordinary shares of 5 pence each 10) Date of transaction Not advised 11) Date company informed 12 7 ~~November~~January ~~2003~~2004 12) Total holding following this notification 40 34,~~545~~196,~~546 Ordinary Shares of 5p each~~620 13) Total percentage holding of issued class following this notification 5 4.~~759~~85% 14) Any additional information N/A 15) Name of contact and telephone number for queries Susan Henderson, Deputy Company Secretary Tel 01494 542063 16) Name and signature of authorised company official responsible for making this notification Susan M Henderson, Date of notification 2112 ~~November~~January ~~2003~~2004 Exhibit No. 5

Exhibit No. 5

SCHEDULE 10

NOTIFICATION OF MAJOR INTERESTS IN SHARES

1) Name of company Amersham plc 2) Name of shareholder having a major interest Deutsche Bank AG London ~~and its direct and indirect subsidiaries~~ 3) Please state whether notification indicates that it is in respect of holding of the shareholder named in 2 above or in respect of a non-beneficial interest or in the case of an individual holder if it is a holding of that person's spouse or children under the age of 18 Non -Beneficial interest 4) Name of the registered holder(s) and, if more than one holder, the number of shares held by each of them Deutsche Bank AG London ~~and its direct and indirect subsidiaries~~ 5) Number of shares/amount of stock acquired Not advised 6) Percentage of issued class N/A 7) Number of shares/amount of stock disposed N/A 8) Percentage of issued class N/A 9) Class of security Ordinary shares of 5 pence each 10) Date of transaction Not advised 11) Date company informed 17 7 ~~November~~January ~~2003~~2004 12) Total holding following this notification 47 58,~~540~~835,~~337~~891 Ordinary Shares of 5p each 13) Total percentage holding of issued class following this notification 6 8.~~752~~34% 14) Any additional information N/A 15) Name of contact and telephone number for queries Susan Henderson, Deputy Company Secretary Tel 01494 542063 16) Name and signature of authorised company official responsible for making this notification Susan M Henderson, Date of notification 2112 ~~November~~January ~~2003~~2004 Exhibit No. 6

Exhibit No. 6

SCHEDULE 10

NOTIFICATION OF MAJOR INTERESTS IN SHARES

1) Name of company Amersham plc 2) Name of shareholder having a major interest ~~Deutsche~~ Morgan ~~Bank~~Stanley AGSecurities ~~London and its direct and indirect subsidiaries~~Limited 3) Please state whether notification indicates that it is in respect of holding of the shareholder named in 2 above or in respect of a non-beneficial interest or in the case of an individual holder if it is a holding of that person's spouse or children under the age of 18 Non -Beneficial interest 4) Name of the registered holder(s) and, if more than one holder, the number of shares held by each of them ~~Deutsche~~ Morgan ~~Bank~~Stanley AGSecurities ~~London and its direct and indirect subsidiaries~~Limited 5) Number of shares/amount of stock acquired Not advised 6) Percentage of issued class N/A 7) Number of shares/amount of stock disposed N/A 8) Percentage of issued class N/A 9) Class of security Ordinary shares of 5 pence each 10) Date of transaction ~~Not~~ 6 ~~advised~~January 2004 11) Date company informed 21 8 ~~November~~January ~~2003~~2004 12) Total holding following this notification 51 22,~~912~~184,~~754 Ordinary Shares of 5p each~~211 13) Total percentage holding of issued class following this notification 7 3.~~373~~15% 14) Any additional information N/A 15) Name of contact and telephone number for queries Susan Henderson, Deputy Company Secretary Tel 01494 542063 16) Name and signature of authorised company official responsible for making this notification Susan M Henderson, Date of notification 2412 ~~November~~January ~~2003~~2004 Exhibit No. 7

SCHEDULE 10

NOTIFICATION OF MAJOR INTERESTS IN SHARES

1)      Name of company

          Amersham plc

2)      Name of shareholder having a major interest

          Legal & General Investment Management Limited

3)      Please state whether notification indicates that it is in respect of holding of the
          shareholder named in 2 above or in respect of a non-beneficial interest or in the case of an
          individual holder if it is a holding of that person's spouse or children under the age of 18

          Non-Beneficial interest

4)      Name of the registered holder(s) and, if more than one holder, the number of shares held by each of them

          Legal & General Investment Management Limited

5)      Number of shares/amount of stock acquired

          Not advised

6)      Percentage of issued class

          N/A

7)      Number of shares/amount of stock disposed

          N/A

8)      Percentage of issued class

          N/A

9)      Class of security

          Ordinary shares of 5 pence each

10)     Date of transaction

          Not advised

11)     Date company informed

          30 December 2003

12)     Total holding following this notification

          21,110,233

13)     Total percentage holding of issued class following this notification

          3.00%

14)     Any additional information

          N/A

15)     Name of contact and telephone number for queries

          Susan Henderson, Deputy Company Secretary Tel 01494 542063

16)     Name and signature of authorised company official responsible for making this notification

          Susan M Henderson,

Date of notification 12 January 2004

SIGNATURE

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

                                                                  AMERSHAM PLC
                                                                                                                                                                                    (Registrant)                                                                                                                                                                                        By: /s/ Susan M. Henderson

                                                                Name: Susan M. Henderson
                                                                          Title: Deputy Company Secretary

Date: ~~December~~January 0215, ~~2003~~2004

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