13F-HR 1 d13fhr.txt MPM BIOEQUITIES ADVISER, LLC UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 13F FORM 13F COVER PAGE Report for the Calendar Year or Quarter Ended: December 31, 2003 -------------------- Check here if Amendment [_]; Amendment Number: _____ This amendment (Check only one.): [_] is a restatement. [_] adds new holdings entries. Institutional Investment Manager Filing this Report: Name: MPM BioEquities Adviser, LLC Address: 601 Gateway Boulevard, Suite 350 South San Francisco, CA 94080 13 File Number: 28-108358 ------------ The institutional investment manager filing this report and the person by whom it is signed hereby represent that the person signing the report is authorized to submit it, that all information contained herein is true, correct, and complete, and that it is understood that all required items, statements, schedules, lists, and tables, are considered integral parts of this form. Person Signing this Report on Behalf of Reporting Manager: Name: Robert W. Liptak Title: Chief Financial Officer Phone: 617-425-9216 Signature, Place and Date of Signing: /s/ Robert W. Liptak South San Francisco, CA 2/12/04 ---------------------- --------------------------- -------------- [Signature] [City, State] [Date] Report Type (Check only one.): [X] 13F HOLDINGS REPORT. (Check here if all holdings of this reporting manager are reported in this report.) [_] 13F NOTICE. (Check here if no holdings reported are in this report, and all holdings are reported by other reporting manager(s).) [_] 13F COMBINATION REPORT. (Check here if a portion of the holdings for this reporting manager are reported in this report and a portion are reported by other reporting manger(s).) List of Other Managers Reporting for this Manager: [If there are no entries in this list, omit this section.] Form 13F File Number Name 28- ------------------------ ------------------------------------ Form 13F Information Table

VOTING AUTHORITY ------------------------------------------------------------------------------------------------------------------------------------ VALUE SHARES/ SH/ PUT/ INVSTMT OTHER NAME OF ISSUER TITLE OF CLASS CUSIP x($1000) PRN AMT ~~SH/~~PRN ~~PUT/~~CALL DISCRETN MANAGERS SOLE SHARED NONE ------------------------------------------------------------------------------------------------------------------------------------ ABGENIX INC COM STK COMMON STOCK 00339B107 ~~2642~~5005 ~~182300~~405300 SH SOLE ~~182300~~405300 0 0 ~~ALEXION~~ADOLOR ~~PHARMACEUTICALS~~CORP ~~INC~~ COMMON STOCK ~~015351109~~00724X102 ~~2631~~1999 ~~155400~~100000 SH SOLE ~~155400~~100000 0 0 ALKERMES INC CONV CONVRT BONDS 01642TAD0 ~~5831~~5981 5000000 PRN SOLE 5000000 0 0 AMGEN INC USD COM COMMON STOCK 031162100 ~~10220~~8981 ~~158396~~145346 SH SOLE ~~158396~~145346 0 0 ANGIOTECH PHARMACEUTICALS INC COMMON STOCK 034918102 ~~5063~~2441 ~~116000~~53200 SH SOLE ~~116000~~53200 0 0 ~~ANTIGENICS INC COMMON STOCK 037032109 3426 283600 SH SOLE 283600 0 0~~ ARIAD PHARMACEUTICALS INC COMMON STOCK 04033A100 ~~2206~~2730 366436 SH SOLE 366436 0 0 ARRAY BIOPHARMA COMMON STOCK 04269X105 ~~3419~~3531 620500 SH SOLE 620500 0 0 ~~ATRIX~~BIOGEN ~~LABS~~IDEC INC COMMON STOCK ~~04962L101~~09062X103 ~~2761~~8850 ~~133600~~241150 SH SOLE ~~133600~~241150 0 0 CELGENE CORPORATION COMMON STOCK 151020104 ~~4031~~3905 ~~93100~~87000 SH SOLE ~~93100~~87000 0 0 CHIRON CORP COMMON STOCK 170040109 ~~9043~~8940 ~~174500~~156900 SH SOLE ~~174500~~156900 0 0 CONNECTICS COMMON STOCK 208192104 3888 214100 SH SOLE 214100 0 0 CUBIST PHARMACEUTICALS INC COMMON STOCK 229678107 ~~1127~~2521 ~~103900~~206600 SH SOLE ~~103900~~206600 0 0 CYTOGEN CORP COMMON STOCK 232824300 435 40000 SH SOLE 40000 0 0 EXACT SCIENCES COMMON STOCK 30063P105 1286 127100 SH SOLE 127100 0 0 EXELISIS INC COM COMMON STOCK 30161Q104 3925 556800 SH SOLE 556800 0 0 FOREST LABS INC COMMON STOCK 345838106 ~~6071~~5061 ~~118000~~81900 SH SOLE ~~118000~~81900 0 0 GENENTECH COMMON STOCK 368710406 5287 56500 SH SOLE 56500 0 0 GENZYME CORP GENL DIV COMMON STOCK 372917104 ~~5219~~2731 ~~112700~~55400 SH SOLE ~~112700~~55400 0 0 ~~HUMAN~~GILEAD ~~GENOME~~ SCIENCES INC COMMON STOCK ~~444903108~~375558103 ~~3507~~3832 ~~255400~~65750 SH SOLE ~~255400~~65750 0 0 ~~IDEC~~ICOS ~~PHARMACEUTICALS~~ CORP ~~COMMON~~COM ~~STOCK~~OPTION ~~449370105~~- ~~8323~~PUTS ~~250000~~4492950MF 4128 100000 SH PUT SOLE ~~250000~~100000 0 0 ILEX ONCOLOGY INC COMMON STOCK 451923106 ~~6200~~3923 ~~369700~~184600 SH SOLE ~~369700~~184600 0 0 ~~INTERMUNE~~IMCLONE SYSTEMS INC COMMON STOCK ~~45884X103~~45245W109 ~~7943~~2614 ~~415200~~65900 SH SOLE ~~415200~~65900 0 0 ISIS PHARMACEUTICALS USD COMMON STOCK 464330109 ~~2134~~2127 327300 SH SOLE 327300 0 0 LA JOLLA PHARMACEUTICALS CO COMMON STOCK 503459109 ~~2993~~3211 753800 SH SOLE 753800 0 0 LEXICON GENETIC COMMON STOCK 528872104 ~~1892~~2175 ~~366700~~369300 SH SOLE ~~366700~~369300 0 0 LIGAND PHARMACEUTICALS INC COMMON STOCK 53220K207 ~~4799~~6606 ~~372000~~449700 SH SOLE ~~372000~~449700 0 0 MEDAREX INC COMMON STOCK 583916101 ~~1377~~2377 ~~233400~~381600 SH SOLE ~~233400~~381600 0 0 MEDIMMUNE INC COM COMMON STOCK 584699102 ~~4852~~2565 ~~146900~~101050 SH SOLE ~~146900~~101050 0 0 ~~MILLENNIUM PHARMACEUTICALS INC COMMON STOCK 599902103 4098 265300 SH SOLE 265300 0 0~~ NEKTAR THERAPEUTICS COMMON STOCK 640268108 ~~6115~~6727 ~~477700~~494300 SH SOLE ~~477700~~494300 0 0 NEOSE TECHNOLOGIES INC COMMON STOCK 640522108 ~~4909~~4830 525000 SH SOLE 525000 0 0 NPS PHARMACEUTICALS COMMON STOCK 62936P103 ~~2429~~4314 ~~87200~~140600 SH SOLE ~~87200~~140600 0 0 ~~PRAECIS~~PENWEST PHARMACEUTICALS ~~INC~~ COMMON STOCK ~~739421105~~709754105 ~~1443~~4391 ~~213500~~254100 SH SOLE ~~213500~~254100 0 0 ~~PROTEIN~~PHARMION ~~DESIGN~~CORP ~~LABS INC~~ COMMON STOCK ~~74369L103~~71715B409 ~~2842~~4006 ~~202300~~262700 SH SOLE ~~202300~~262700 0 0 ~~QLT~~SALIX ~~INC~~PHARMACEUTICALS COMMON STOCK ~~746927102~~795435106 ~~6279~~2282 ~~392700~~100600 SH SOLE ~~392700~~100600 0 0 ~~SALIX~~SEPRACOR ~~PHARMACEUTICALS~~INC COMMON STOCK ~~795435106~~817315104 ~~4193~~5202 ~~217700~~217400 SH SOLE ~~217700~~217400 0 0 SERONO SA -ADR ADRS STOCKS 81752M101 ~~3920~~4217 ~~239300~~240300 SH SOLE ~~239300~~240300 0 0 ~~SONUS~~SUPERGEN ~~PHARMACEUTICALS~~UNC ~~COMMON~~COM ~~STOCK~~OPTION ~~835692997~~- ~~2804~~CALLS ~~569999~~8680590DB SH3300 ~~SOLE~~300000 ~~569999 0 0 UNITED THERAPEUTICS CORP COMMON STOCK 91307C102 4414 195400~~ SH ~~SOLE~~CALL ~~195400 0 0 VERTEX PHARMACEUTICALS INC COMMON STOCK 92532F100 5189 421900 SH~~ SOLE ~~421900~~300000 0 0 S REPORT SUMMARY 3637 Data Records ~~156344~~150325 0 OTHER MANAGERS ON WHOSE BEHALF REPORT IS FILED

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