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UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM 10-Q

(Mark One)


☒	QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

For the quarterly period ended September 30, 2025


☐	TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to

Commission File Number 001-40360

Mind Medicine (MindMed) Inc.

(Exact name of Registrant as specified in its Charter)


British Columbia, Canada	98-1582438
(State or other jurisdiction of incorporation or organization)	(I.R.S. Employer Identification No.)
One World Trade Center, Suite 8500 New York, New York	10007
(Address of principal executive offices)	(Zip Code)

Registrant’s telephone number, including area code: (212) 220-6633

Securities registered pursuant to Section 12(b) of the Act:

     Title of each class

     Trading
Symbol(s)

     Name of each exchange on which registered

     Common Shares, no par value per share

     MNMD

     The Nasdaq Stock Market LLC
(The Nasdaq Global Select Market)

Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days. Yes ☒ No ☐

Indicate by check mark whether the registrant has submitted electronically every Interactive Data File required to be submitted pursuant to Rule 405 of Regulation S-T (§232.405 of this chapter) during the preceding 12 months (or for such shorter period that the registrant was required to submit such files). Yes ☒ No ☐

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company, or an emerging growth company. See the definitions of “large accelerated filer,” “accelerated filer,” “smaller reporting company,” and “emerging growth company” in Rule 12b-2 of the Exchange Act.

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐

Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act). Yes ☐ No ☒

As of October 31, 2025 the registrant had 98,509,279 Common Shares outstanding.

Table of Contents


		Page
PART I	FINANCIAL INFORMATION	4
Item 1.	Financial Statements	4
	Condensed Consolidated Balance Sheets	4
	Condensed Consolidated Statements of Operations and Comprehensive Loss	5
	Condensed Consolidated Statements of Shareholders' Equity	6
	Condensed Consolidated Statements of Cash Flows	7
	Notes to Condensed Consolidated Financial Statements	9
Item 2.	Management’s Discussion and Analysis of Financial Condition and Results of Operations	21
Item 3.	Quantitative and Qualitative Disclosures About Market Risk	31
Item 4.	Controls and Procedures	31

PART II	OTHER INFORMATION	32

Item 1.	Legal Proceedings	32
Item 1A.	Risk Factors	32
Item 2.	Unregistered Sales of Equity Securities and Use of Proceeds	33
Item 3.	Defaults Upon Senior Securities	33
Item 4.	Mine Safety Disclosures	33
Item 5.	Other Information	33
Item 6.	Exhibits	34
Signatures		35

SPECIAL NOTE REGARDING FORWARD-LOOKING STATEMENTS

This Quarterly Report on Form 10-Q ("Quarterly Report") contains forward-looking statements about us and our industry that involve substantial risks and uncertainties. All statements other than statements of historical facts contained in this Quarterly Report, including statements regarding our future results of operations or financial condition, business strategy and plans and objectives of management for future operations, are forward-looking statements. In some cases, you can identify forward-looking statements because they contain words such as “anticipate,” “believe,” “contemplate,” “continue,” “could,” “estimate,” “expect,” “intend,” “may,” “plan,” “potential,” “predict,” “project,” “should,” “target,” “will” or “would” or the negative of these words or other similar terms or expressions. These forward-looking statements include, but are not limited to, statements concerning the following:

•

the timing, progress and results of our investigational programs for MM120, a proprietary, pharmaceutically optimized form of lysergide D-tartrate (LSD), and MM402, a proprietary form of the R-enantiomer of 3,4-methylenedioxymethamphetamine, also referred to as R(-)-MDMA (together, our “lead product candidates”) and any other product candidates (together with our lead product candidates, our “product candidates”);

•

our reliance on the success of our investigational MM120 product candidate;

•

our expectations regarding our cash runway;

•

the protocols and timing of availability of data from our ongoing Phase 3 clinical program for MM120 orally disintegrating tablet (“ODT”) in generalized anxiety disorder (“GAD”);

•

the protocol and timing of availability of data from our ongoing Phase 3 clinical program for MM120 ODT in major depressive disorder (“MDD”);

•

the timing, scope or likelihood of regulatory filings and approvals and our ability to obtain and maintain regulatory approvals for product candidates for any indication;

•

the impact of adverse global economic conditions, including trade policies, public health crises, geopolitical conflicts, fluctuations in interest rates, supply-chain disruptions and inflation, on our financial condition and operations;

•

our expectations regarding the size of the eligible patient populations for our lead product candidates, if approved and commercialized;

•

our ability to identify third-party treatment sites to conduct our trials and our ability to identify and train appropriate qualified healthcare practitioners to administer our treatments;

•

our ability to implement our business model and our strategic plans for our product candidates;

•

our ability to identify new indications for our lead product candidates beyond our current primary focuses;

•

our ability to achieve profitability and then sustain such profitability;

•

our commercialization, marketing and manufacturing capabilities and strategy;

•

the pricing, coverage and reimbursement of our lead product candidates, if approved and commercialized;

•

the rate and degree of market acceptance and clinical utility of our lead product candidates, in particular, and controlled substances, in general;

•

future investments in our business, our anticipated capital expenditures and our estimates regarding our capital requirements;

•

our ability to establish or maintain collaborations or strategic relationships or to obtain additional funding;

•

our expectations regarding potential benefits of our lead product candidates;

•

our ability to maintain effective patent rights and other intellectual property protection for our product candidates, and to prevent competitors from using technologies we consider important in our successful development and commercialization of our product candidates;

•

infringement or alleged infringement on the intellectual property rights of third parties;

•

legislative and regulatory developments in the United States, including individual states, the UK, the European Union and other jurisdictions, including decisions by the U.S. Drug Enforcement Administration and states to reschedule any of our product candidates, if approved, containing Schedule I controlled substances, before they may be legally marketed in the U.S.;

•

the effectiveness of our internal control over financial reporting;

•

actions of activist shareholders against us that have previously been and could be disruptive and costly and may result in litigation and have an adverse effect on our business and share price;

•

our Amended Loan Agreement (as defined herein) contains certain covenants that could adversely affect our operations and, if an event of default were to occur, we could be forced to repay any outstanding indebtedness sooner than planned and possibly at a time when we do not have sufficient capital to meet this obligation;

•

our expectations regarding our revenue, expenses and other operating results;

•

the costs and success of our marketing efforts, and our ability to promote our brand;

•

our reliance on key personnel and our ability to identify, recruit and retain skilled personnel;

•

our ability to effectively manage our growth; and

•

our ability to compete effectively with existing competitors and new market entrants.

You should not rely on forward-looking statements as predictions of future events. We have based the forward-looking statements contained in this Quarterly Report primarily on our current expectations and projections about future events and trends that we believe may affect our business, financial condition and operating results. The outcome of the events described in these forward-looking statements is subject to risks, uncertainties and other factors described in the section titled “Risk Factors” previously disclosed in Part I, Item 1A. in our Annual Report on Form 10-K, as filed with the U.S. Securities and Exchange Commission (“SEC”) on March 6, 2025 (the “2024 Annual Report”) and in Part II, Item 1A in this Quarterly Report and the section titled “Management's Discussion and Analysis of Financial Condition and Results of Operations” in Part I, Item 2 of this Quarterly Report. Moreover, we operate in a very competitive and rapidly changing environment. New risks and uncertainties emerge from time to time, and it is not possible for us to predict all risks and uncertainties that could have an impact on the forward-looking statements contained in this Quarterly Report. The results, events and circumstances reflected in the forward-looking statements may not be achieved or occur, and actual results, events or circumstances could differ materially from those described in the forward-looking statements.

In addition, statements that “we believe” and similar statements reflect our beliefs and opinions on the relevant subject. These statements are based on information available to us as of the date of this Quarterly Report. And while we believe that information provides a reasonable basis for these statements, that information may be limited or incomplete. Our statements should not be read to indicate that we have conducted an exhaustive inquiry into, or review of, all relevant information. These statements are inherently uncertain, and investors are cautioned not to unduly rely on these statements.

The forward-looking statements made in this Quarterly Report relate only to events as of the date on which the statements are made. We undertake no obligation to update any forward-looking statements made in this Quarterly Report to reflect events or circumstances after the date of this Quarterly Report or to reflect new information or the occurrence of unanticipated events, except as required by law. We may not actually achieve the plans, intentions or expectations disclosed in our forward-looking statements, and you should not place undue reliance on our forward-looking statements. Our forward-looking statements do not reflect the potential impact of any future acquisitions, mergers, dispositions, joint ventures or investments.

We may announce material business and financial information to our investors using our investor relations website (https://ir.mindmed.co/). We therefore encourage investors and others interested in our company to review the information that we make available on our website, in addition to following our filings with the SEC, webcasts, press releases and conference calls. Our website and information included in or linked to our website are not part of this Quarterly Report. Unless otherwise noted or the context indicates otherwise, references in this Quarterly Report to the “Company,” “MindMed,” “we,” “us,” and “our” refer to Mind Medicine (MindMed) Inc. and its consolidated subsidiaries.

PART I—FINANCIAL INFORMATION

Item 1. Financial Statements.

Mind Medicine (MindMed) Inc.

Condensed Consolidated Balance Sheets


(in thousands, except share amounts)	September 30, 2025 (unaudited)			December 31, 2024
Assets
Current assets:
Cash and cash equivalents	$	19,959		$	273,741
Short-term investments		189,111			—
Prepaid and other current assets		6,778			7,879
Total current assets		215,848			281,620
Goodwill		19,918			19,918
Other non-current assets		1,150			613
Total assets	$	236,916		$	302,151

Liabilities and Shareholders’ Equity
Current liabilities:
Accounts payable	$	8,113		$	2,010
Accrued expenses		19,028			12,829
2022 USD Financing Warrants		38,275			24,010
Total current liabilities		65,416			38,849
Credit facility, long-term		40,385			21,854
Other non-current liabilities		519			—
Total liabilities		106,320			60,703

Commitments and contingencies (Note 10)
Shareholders' equity:
Common shares, no par value, unlimited authorized as of September 30, 2025 and December 31, 2024; 76,774,057 and 75,100,763 issued and outstanding as of September 30, 2025 and December 31, 2024, respectively		—			—
Additional paid-in capital		661,831			639,508
Accumulated other comprehensive income		1,001			819
Accumulated deficit		(532,236	)		(398,879	)
Total shareholders' equity		130,596			241,448
Total liabilities and shareholders' equity	$	236,916		$	302,151

See accompanying notes to unaudited condensed consolidated financial statements.

Mind Medicine (MindMed) Inc.

Condensed Consolidated Statements of Operations and Comprehensive Loss

(Unaudited)


	Three Months Ended September 30,						Nine Months Ended September 30,
(in thousands, except share and per share amounts)	2025			2024			2025			2024
Operating expenses:
Research and development	$	30,978		$	17,188		$	84,144		$	43,538
General and administrative		14,691			7,604			34,587			27,916
Total operating expenses		45,669			24,792			118,731			71,454
Loss from operations		(45,669	)		(24,792	)		(118,731	)		(71,454	)
Other income/(expense):
Interest income		2,262			3,507			7,469			8,279
Interest expense		(1,274	)		(727	)		(4,214	)		(1,627	)
Foreign exchange loss, net		(39	)		(32	)		(107	)		(589	)
Change in fair value of 2022 USD Financing Warrants		(22,545	)		8,360			(17,774	)		(11,088	)
Gain on extinguishment of contribution payable		—			—			—			2,541
Total other income/(expense)		(21,596	)		11,108			(14,626	)		(2,484	)
Net loss		(67,265	)		(13,684	)		(133,357	)		(73,938	)
Other comprehensive loss
Unrealized gain on investments		196			—			242			—
Gain/(loss) on foreign currency translation		(2	)		(12	)		(60	)		478
Comprehensive loss	$	(67,071	)	$	(13,696	)	$	(133,175	)	$	(73,460	)
Net loss per common share, basic	$	(0.78	)	$	(0.18	)	$	(1.56	)	$	(1.12	)
Net loss per common share, diluted	$	(0.78	)	$	(0.27	)	$	(1.56	)	$	(1.12	)
Weighted-average common shares, basic		85,885,516			77,909,441			85,436,678			65,938,025
Weighted-average common shares, diluted		85,885,516			80,238,688			85,436,678			65,938,025

See accompanying notes to unaudited condensed consolidated financial statements.

Mind Medicine (MindMed) Inc.

Condensed Consolidated Statements of Shareholders’ Equity

(Unaudited)


	Common Shares
(in thousands, except share amounts)	Shares		Amount		Additional Paid-In Capital			Accumulated OCI			Accumulated Deficit			Total
Balance, December 31, 2024		75,100,763	$	—	$	639,508		$	819		$	(398,879	)	$	241,448
Issuance of common shares under employee share purchase plan ("ESPP")		34,017		—		186			—			—			186
Issuance of common shares upon settlement of restricted share unit ("RSU") awards		186,708		—		—			—			—			—
Exercise of 2022 USD Financing Warrants		136,346		—		874			—			—			874
Stock-based compensation expense		—		—		3,426			—			—			3,426
Exercise of stock options		53,541		—		237			—			—			237
Net loss and comprehensive loss		—		—		—			(17	)		(23,348	)		(23,365	)
Balance, March 31, 2025		75,511,375	$	—	$	644,231		$	802		$	(422,227	)	$	222,806
Issuance of common shares upon settlement of RSU awards		229,587		—		—			—			—			—
Stock-based compensation expense		—		—		5,253			—			—			5,253
Exercise of stock options, net of shares withheld for exercise and tax		62,289		—		80			—			—			80
Net loss and comprehensive loss		—		—		—			5			(42,744	)		(42,739	)
Balance, June 30, 2025		75,803,251	$	—	$	649,564		$	807		$	(464,971	)	$	185,400
Issuance of common shares under ESPP		32,148		—	$	226			—			—			226
Issuance of common shares upon settlement of RSU awards		221,863		—		—			—			—			—
Exercise of 2022 USD Financing Warrants		450,000		—		5,127			—			—			5,127
Issuance of common shares upon conversion of loan principal		249,377		—		1,000			—			—			1,000
Stock-based compensation expense		—		—		5,816			—			—			5,816
Exercise of stock options, net of shares withheld for exercise and tax		17,418		—		98			—			—			98
Net loss and comprehensive loss		—		—		—			194			(67,265	)		(67,071	)
Balance, September 30, 2025		76,774,057	$	—	$	661,831		$	1,001		$	(532,236	)	$	130,596

Balance, December 31, 2023		41,101,303	$	—	$	367,991		$	343		$	(290,200	)	$	78,134
Issuance of common shares, net of share issuance costs		29,338,553		—		164,298			—			—			164,298
Issuance of common shares upon settlement of RSU awards, net of shares withheld for tax		204,968		—		(54	)		—			—			(54	)
Exercise of 2022 USD Financing Warrants		400,000		—		3,369			—			—			3,369
Stock-based compensation expense		—		—		3,689			—			—			3,689
Exercise of stock options		118,896		—		530			—			—			530
Net loss and comprehensive loss		—		—		—			493			(54,400	)		(53,907	)
Balance, March 31, 2024		71,163,720	$	—	$	539,823		$	836		$	(344,600	)	$	196,059
Issuance of common shares upon settlement of RSU awards, net of shares withheld for tax		239,834		—		—			—			—			—
Exercise of 2022 USD Financing Warrants		642,523		—		6,306			—			—			6,306
Stock-based compensation expense		—		—		5,430			—			—			5,430
Exercise of stock options		28,999		—		109			—			—			109
Net loss and comprehensive loss		—		—		—			(3	)		(5,854	)		(5,857	)
Balance, June 30, 2024		72,075,076	$	—	$	551,668		$	833		$	(350,454	)	$	202,047
Issuance of common shares, net of share issuance costs		9,285,511		—		69,969			—			—			69,969
Issuance of common shares upon settlement of RSU awards, net of shares withheld for tax		205,999		—		—			—			—			—
Stock-based compensation expense		—		—		3,841			—			—			3,841
Exercise of stock options, net of shares withheld for tax		23,905		—		32			—			—			32
Net loss and comprehensive loss		—		—		—			(12	)		(13,684	)		(13,696	)
Balance, September 30, 2024		81,590,491	$	—	$	625,510		$	821		$	(364,138	)	$	262,193

See accompanying notes to unaudited condensed consolidated financial statements.

Mind Medicine (MindMed) Inc.

Condensed Consolidated Statements of Cash Flows

(Unaudited)


	Nine Months Ended September 30,
(in thousands)	2025				2024
Cash flows from operating activities
Net loss	$	(133,357	)		$	(73,938	)
Adjustments to reconcile net loss to net cash used in operating activities:
Stock-based compensation		14,495				12,960
Change in fair value on directors' deferred share units ("DDSU")		1,044				508
Amortization of intangible assets		—				527
Change in fair value of the 2022 USD Financing Warrants		17,774				11,088
Gain on extinguishment of contribution payable		—				(2,541	)
Accretion of discounts and premiums on investments, net		(2,279	)			—
Unrealized foreign exchange		—				509
Other non-cash adjustments		14				228
Changes in operating assets and liabilities:
Prepaid and other current assets		2,590				(532	)
Other noncurrent assets		13				115
Accounts payable		6,103				(1,987	)
Accrued expenses		5,035				(683	)
Other liabilities, long-term		(17	)			(32	)
Net cash used in operating activities		(88,585	)			(53,778	)
Cash flows from investing activities
Purchases of investments		(262,340	)			—
Maturity of investments		75,750				—
Net cash used in investing activities		(186,590	)			—
Cash flows from financing activities
Proceeds from credit facility		42,000		(1)		10,000
Repayment of credit facility		(22,000	)	(1)		—
Payment of credit facility issuance costs		(447	)			(128	)
Proceeds from the Offerings and Private Placement		—				249,999
Payment of issuance costs from the Offerings and Private Placement		—				(16,090	)
Proceeds from the 2022 ATM net of issuance costs		—				984
Payment of deferred financing fees related to 2024 ATM		—				(424	)
Proceeds from exercise of 2022 USD Financing Warrants		1,004				4,431
Proceeds from exercise of options		432				671
Proceeds from issuance of common shares under ESPP		412				—
Withholding taxes paid on vested RSUs		—				(54	)
Net cash provided by financing activities		21,401				249,389
Effect of exchange rate changes on cash		(8	)			(31	)
Net (decrease)/increase in cash and cash equivalents		(253,782	)			195,580
Cash and cash equivalents, beginning of period		273,741				99,704
Cash and cash equivalents, end of period	$	19,959			$	295,284

(1)

As discussed in Note 11, Credit Facility, the Amended Loan Agreement (as defined herein) with K2 HealthVentures LLC executed on April 18, 2025 was accounted for as a modification. The Company used the proceeds from the Amended Loan Agreement to repay the outstanding amounts under the Loan Agreement (as defined herein) from K2 HealthVentures LLC.

Mind Medicine (MindMed) Inc.

Condensed Consolidated Statements of Cash Flows (continued)

(Unaudited)


	Nine Months Ended September 30,
(in thousands)	2025		2024
Supplemental Cash Flow Information
Cash paid for interest and final payment for credit facility	$	4,646	$	1,541
Supplemental Noncash Disclosures
Conversion of 2022 USD Financing Warrants to common shares upon exercise of warrants		3,509		5,244
Proceeds from exercise of 2022 USD Financing Warrants in prepaid and other current assets		1,488		—
Issuance of common shares upon conversion of loan principal		1,000		—
Lease liabilities arising from obtaining right-of-use assets		586		—
Withholding taxes payable on option exercises		17		—
Deferred financing fees related to 2024 ATM included in accrued expenses		—		6
Reclass of deferred financing fees to additional paid-in capital		—		332

See accompanying notes to unaudited condensed consolidated financial statements.

Mind Medicine (MindMed) Inc.

Notes to Unaudited Condensed Consolidated Financial Statements

DESCRIPTION OF THE BUSINESS

Mind Medicine (MindMed) Inc. (the “Company” or “MindMed”) is incorporated under the laws of the Province of British Columbia. Its wholly owned subsidiaries, Mind Medicine, Inc. (“MindMed US”), HealthMode, Inc., MindMed Pty Ltd., and MindMed GmbH are incorporated in Delaware, Delaware, Australia and Switzerland, respectively. MindMed US was incorporated on May 30, 2019.

MindMed is a late-stage clinical biopharmaceutical company developing novel product candidates to treat brain health disorders. The Company’s mission is to be the global leader in the development and delivery of treatments for brain health disorders that unlock new opportunities to improve patient outcomes. The Company is developing a pipeline of innovative product candidates targeting neurotransmitter pathways that play key roles in brain health. This specifically includes pharmaceutically optimized product candidates derived from the psychedelic and empathogen drug classes, including MM120 and MM402, the Company’s lead product candidates.

Liquidity

As of September 30, 2025, the Company had an accumulated deficit of $532.2 million. Through September 30, 2025, the Company’s financial support has primarily been provided by proceeds from the issuance of its common shares, no par value per share (“Common Shares”) and warrants to purchase Common Shares, and the Company’s credit facility.

As the Company continues its expansion, it may seek additional financing and/or strategic investments; however, there can be no assurance that any additional financing or strategic investments will be available to the Company on acceptable terms, if at all. If events or circumstances occur such that the Company does not obtain additional funding, it will most likely be required to reduce its plans and/or certain discretionary spending, which could have a material adverse effect on the Company’s ability to achieve its intended business objectives. The accompanying unaudited condensed consolidated financial statements do not include any adjustments that might be necessary if it were unable to continue as a going concern. Management believes that it has sufficient cash, cash equivalents and investments to fund operations through at least the next twelve months from the date of the issuance of these unaudited condensed consolidated financial statements.

Emerging Growth Company Status

The Company is an emerging growth company, as defined in the Jumpstart Our Business Startups Act of 2012 (the “JOBS Act”). Under the JOBS Act, emerging growth companies can delay adopting new or revised accounting standards issued subsequent to the enactment of the JOBS Act until such time as those standards apply to private companies. The Company has elected to use the extended transition period for complying with new or revised accounting standards, and as a result of this election, the unaudited condensed consolidated financial statements may not be comparable to companies that comply with public company Financial Accounting Standards Board (“FASB”) standards’ effective dates. The Company may take advantage of these exemptions up until the last day of the fiscal year following the fifth anniversary of the first sale of its common equity securities under an effective Securities Act of 1933 (the "Securities Act") registration statement or such earlier time that it is no longer an emerging growth company.

In the opinion of management, these unaudited condensed consolidated financial statements reflect all adjustments necessary for a fair presentation of the Company's financial position and results of operations and cash flows for the periods presented.

BASIS OF pRESENTATION AND Summary of Significant Accounting Policies

Basis of Presentation

The accompanying unaudited condensed consolidated financial statements have been prepared in conformity with generally accepted accounting principles in the United States of America (“U.S. GAAP”). Any reference in these notes to applicable guidance is meant to refer to the authoritative U.S. GAAP as found in the Accounting Standards Codification and as amended by Accounting Standards Updates of FASB. The accompanying unaudited condensed consolidated financial statements should be read in conjunction with the audited consolidated financial statements and the related notes thereto for the year ended December 31, 2024, which are included in the Company’s 2024 Annual Report on Form 10-K filed with the SEC on March 6, 2025 (the “2024 Annual Report”). The Company’s significant accounting policies are disclosed in the audited consolidated financial statements for the periods ended December 31, 2024 and 2023, included in the 2024 Annual Report. Since the date of those financial statements, there have been no changes to the Company's significant accounting policies.

The preparation of financial statements in conformity with U.S. GAAP requires management to make a number of estimates and assumptions relating to the reporting of assets and liabilities and the disclosure of contingent assets and liabilities at the dates of the financial statements and the reported amounts of expenses during the reporting periods. Actual results could differ from those estimates under different assumptions or conditions.

Intercompany balances and transactions, and any unrealized income and expenses arising from intercompany transactions, are eliminated in preparing the unaudited condensed consolidated financial statements.

Foreign Currency

Prior to April 1, 2024, the Company’s functional currency was the Canadian dollar (“CAD”). Translation gains and losses from the application of the U.S. dollar (“USD”) as the reporting currency during the period that the Canadian dollar was the functional currency were included as part of cumulative currency translation adjustment, which is reported as a component of shareholders’ equity as accumulated other comprehensive income.

Following the Company’s voluntary delisting from Cboe Canada in April 2024, the Company reassessed its functional currency and determined that, as of April 1, 2024, its functional currency had changed from the CAD to the USD.

For periods commencing April 1, 2024, monetary assets and liabilities denominated in currencies other than USD are remeasured at period-end using the period-end exchange rate. Opening balances related to non-monetary assets and liabilities are based on prior period translated amounts, and non-monetary assets acquired, and non-monetary liabilities incurred after April 1, 2024, are translated at the approximate exchange rate prevailing at the date of the transaction. Income and expense accounts are translated at the average rates in effect during the fiscal year. Foreign exchange gains and losses are included in the unaudited condensed consolidated statements of operations and comprehensive loss.

Cash Equivalents

The Company considers all investments with an original maturity date at the time of purchase of three months or less to be cash equivalents. As of September 30, 2025, the Company’s cash equivalents consisted of U.S. government money market funds at a high-credit quality and federally insured financial institution. The Company’s accounts may, at times, exceed federally insured limits. The Company had cash equivalents of $15.6 million as of September 30, 2025, and $271.5 million as of December 31, 2024.

Short-Term Investments

All investments are carried at fair value as determined based upon quoted market prices or pricing models for similar securities at period end. The Company has classified these investments as available-for-sale securities, as the sale of such investments may be required prior to maturity to implement management strategies, and therefore has classified all investments with maturity dates beyond three months at the date of purchase as current assets in the accompanying unaudited balance sheets. Dividend and interest income are recognized when earned. Realized gains and losses are included in earnings and are derived using the specific identification method for determining the cost of securities sold. Unrealized gains and losses are reported as a component of accumulated other comprehensive income (loss).

The Company reviews its portfolio of available-for-sale debt securities, using both quantitative and qualitative factors, to determine if declines in fair value below cost have resulted from a credit-related loss or other factors. If the decline in fair value is due to credit-related factors, a loss is recognized in statements of operations, whereas if the decline in fair value is not due to credit-related factors, the loss is recorded in other comprehensive income (loss). The fair value of the Company's investments was $189.1 million as of September 30, 2025. The Company had no investments as of December 31, 2024.

Net Loss per Share

The following table sets forth the computation of basic and diluted net loss per share attributable to common shareholders (in thousands, except share and per share amounts). As the exercise price of the Company’s pre-funded warrants is $0.001 per share, it was determined to be non-substantive for accounting purposes and the pre-funded warrants were included in the denominator of both basic and diluted loss per share:


	Three Months Ended September 30,						Nine Months Ended September 30,
	2025			2024			2025			2024
Numerator:
Net loss attributable to common shareholders, basic	$	(67,265	)	$	(13,684	)	$	(133,357	)	$	(73,938	)
Change in fair value of the 2022 USD Financing Warrants		—			(8,360	)		—			—
Net loss attributable to common shareholders, diluted	$	(67,265	)	$	(22,044	)	$	(133,357	)	$	(73,938	)
Denominator:
Weighted-average pre-funded warrants used in computing net loss per share attributable to common shareholders, basic		9,753,775			823,099			9,753,775			276,369
Weighted-average shares used in computing net loss per share attributable to common shareholders, basic		76,131,741			77,086,342			75,682,903			65,661,656
Total weighted-average shares used in computing net loss per share attributable to common shareholders, basic		85,885,516			77,909,441			85,436,678			65,938,025
Incremental shares from 2022 USD Financing Warrants		—			2,329,247			—			—
Total weighted-average shares used in computing net loss per share attributable to common shareholders, diluted		85,885,516			80,238,688			85,436,678			65,938,025

Net loss per share:
Basic	$	(0.78	)	$	(0.18	)	$	(1.56	)	$	(1.12	)
Diluted	$	(0.78	)	$	(0.27	)	$	(1.56	)	$	(1.12	)

The following potentially dilutive securities have been excluded from the calculation of diluted net loss per share due to their anti-dilutive effect:


	Three Months Ended September 30,				Nine Months Ended September 30,
	2025		2024		2025		2024
2022 USD Financing Warrants		4,499,954		—		4,499,954		5,989,300
Stock options		5,904,191		3,698,252		5,904,191		3,698,252
RSUs		5,791,996		1,552,862		5,791,996		1,552,862
Conversion Shares		760,683		997,506		760,683		997,506
Estimated ESPP shares		47,602		37,370		47,602		37,370
Total		17,004,426		6,285,990		17,004,426		12,275,290

INVESTMENTS

The Company's available-for-sale investments consisted of the following (in thousands):


	As of September 30, 2025
	Amortized Cost		Unrealized Gain		Unrealized Losses			Estimated Fair Value
Investments:
U.S. agency bonds		188,868		251		(8	)		189,111
Total	$	188,868	$	251	$	(8	)	$	189,111

The following table summarizes the maturities of the Company's investments at September 30, 2025:


(in thousands)	Amortized Cost		Estimated Fair Value
Due in one year or less	$	152,236	$	152,327
Due in one to two years		29,619		29,730
Due in two to three years		7,013		7,054
Total	$	188,868	$	189,111

The Company has determined that there were no material declines in the fair value of its investments due to credit-related factors as of September 30, 2025. The Company held no available-for-sale investments as of December 31, 2024.

FAIR VALUE OF FINANCIAL INSTRUMENTS

The following table presents information about the Company’s assets and liabilities measured at the fair value on a recurring basis as of September 30, 2025 and December 31, 2024 (in thousands), and the fair value hierarchy of the valuation techniques utilized.


	As of September 30, 2025
	Level 1		Level 2		Level 3		Total
Financial assets:
Cash equivalents	$	15,634	$	—	$	—	$	15,634
U.S. agency bonds		—		189,111		—		189,111
Total	$	15,634	$	189,111	$	—	$	204,745
Financial liabilities:
DDSU Liability	$	2,192	$	—	$	—	$	2,192
2022 USD Financing Warrant Liability		—		—		38,275		38,275
Total	$	2,192	$	—	$	38,275	$	40,467

	As of December 31, 2024
	Level 1		Level 2		Level 3		Total
Financial assets:
Cash equivalents	$	271,537	$	—	$	—	$	271,537
Financial liabilities:
DDSU Liability	$	1,148	$	—	$	—	$	1,148
2022 USD Financing Warrant Liability		—		—		24,010	$	24,010
Total	$	1,148	$	—	$	24,010	$	25,158

There were no transfers into or out of Level 1, Level 2, or Level 3 during the nine months ended September 30, 2025 and the year ended December 31, 2024.

The Company issued liability-classified warrants to purchase Common Shares in its underwritten public offering that closed on September 30, 2022 (the “2022 USD Financing Warrants”). The warrant liability is measured at fair value on a recurring basis and is classified as Level 3 in the fair value hierarchy. Its fair value is determined using the Black-Scholes option pricing model using the following assumptions:


	As of September 30, 2025	As of December 31, 2024
Share price	$11.79	$6.96
Expected volatility	82.42%	90.70%
Risk-free rate	3.57%	4.18%
Expected life	2.00 years	2.75 years

GOODWILL

During the nine months ended September 30, 2025, the Company had made no additions to its outstanding goodwill. There were no triggering events identified, no indication of impairment of the Company’s goodwill, and no impairment charges recorded during the three and nine months ended September 30, 2025 and 2024, respectively.

ACCRUED EXPENSES

At September 30, 2025 and December 31, 2024, accrued expenses consisted of the following (in thousands):


	As of September 30, 2025		As of December 31, 2024
Accrued compensation	$	7,332	$	6,405
Accrued clinical trial costs		8,209		4,332
Accrued other research and development costs		1,301		841
Professional services		1,688		973
Other accruals		498		278
Total	$	19,028	$	12,829

SHAREHOLDERS' EQUITY

Common Shares

The Company is authorized to issue an unlimited number of Common Shares, which have no par value. As of September 30, 2025, the Company had 76,774,057 Common Shares issued and outstanding.

At-The-Market Facilities

On May 4, 2022, the Company filed a shelf registration statement on Form S-3 (the “2022 Registration Statement”), as well as an accompanying prospectus supplement (the “Prior ATM Prospectus”). In connection with the filing of the 2022 Registration Statement and Prior ATM Prospectus, the Company also entered into a sales agreement (the “Prior Sales Agreement”) with Cantor Fitzgerald & Co. and Oppenheimer & Co. Inc. as sales agents (together, the “Prior Sales Agents”), pursuant to which the Company was able to issue and sell Common Shares for an aggregate offering price of up to $100.0 million under an at-the-market offering program (the “Prior ATM”). During the nine months ended September 30, 2024, the Company sold 171,886 Common Shares for net proceeds of $0.7 million under the Prior ATM. As of March 7, 2024, the Company had raised an aggregate of $40.9 million under the Prior ATM and had the remaining availability of $59.1 million. On March 7, 2024, the Company announced that it had delivered written notice to the Prior Sales Agents that it was suspending and terminating the Prior ATM Prospectus. On May 28, 2024, the Company delivered written notice to the Prior Sales Agents that it was terminating the Prior Sales Agreement.

On June 28, 2024, the Company filed a shelf registration statement on Form S-3 (the “2024 Registration Statement”), as well as an accompanying prospectus supplement for a new at-the-market offering program (“New ATM Prospectus”). In connection with the filing of the 2024 Registration Statement and the New ATM Prospectus, the Company entered into a sales agreement (the "Sales Agreement") with Leerink Partners LLC (the “Sales Agent”) pursuant to which the Company may issue and sell from time to time Common Shares for an aggregate offering price of up to $150.0 million in accordance with the New ATM Prospectus under an at-the-market offering program (the "2024 ATM"). Pursuant to the 2024 ATM, the Company will pay the Sales Agent a commission rate of up to 3.0% of the gross proceeds from the sale of any Common Shares. The Company is not obligated to make any sales of its

Common Shares under the 2024 ATM. The Company has not sold any Common Shares under the 2024 ATM as of September 30, 2025.

March 2024 Offering and Private Placement

On March 7, 2024, the Company entered into an underwriting agreement with Leerink Partners LLC and Cantor Fitzgerald & Co., as representatives of the underwriters named therein, in connection with the issuance and sale by the Company in an underwritten offering (the “March 2024 Offering”) of 16,666,667 Common Shares, at an offering price of $6.00 per share, less underwriting discounts and commissions.

The net proceeds to the Company from the March 2024 Offering were $93.5 million, after deducting underwriting discounts and commissions and other estimated offering expenses payable by the Company.

Also on March 7, 2024, the Company entered into a securities purchase agreement with certain investors, pursuant to which the investors agreed to purchase, and the Company agreed to sell 12,500,000 Common Shares (the “Private Placement Shares”), at a price of $6.00 per Private Placement Share, in a private placement transaction (the “March 2024 Private Placement”).

The net proceeds to the Company from the March 2024 Private Placement were $70.1 million, after deducting fees and expenses payable by the Company.

The Company is using the net proceeds from the March 2024 Offering and the March 2024 Private Placement for the research and development of the Company’s product candidates and working capital and general corporate purposes.

The March 2024 Offering and the March 2024 Private Placement closed on March 11, 2024.

August 2024 Offering

On August 9, 2024, the Company entered into an underwriting agreement with Leerink Partners LLC and Evercore Group L.L.C., as representatives of the several underwriters named therein, in connection with an underwritten public offering (the “August 2024 Offering”) of (i) 9,285,511 Common Shares (the “Shares”), and (ii) to certain investors, pre-funded warrants (the “Pre-Funded Warrants”) to purchase 1,428,775 Common Shares (the "Pre-Funded Warrant Shares"). The offering price for the Shares was $7.00 per share, less underwriting discounts and commissions. The offering price for the Pre-Funded Warrants was $6.999 per Pre-Funded Warrant, less underwriting discounts and commissions, which represents the per share public offering price for the Shares less a $0.001 per share exercise price for each such Pre-Funded Warrant.

The net proceeds to the Company from the August 2024 Offering were approximately $70.0 million, after deducting underwriting discounts and commissions and other offering expenses payable by the Company. The August 2024 Offering closed on August 12, 2024.

The Company is using the net proceeds from the August 2024 Offering to fund the research and development of its product candidates and for working capital and general corporate purposes.

The Pre-Funded Warrants are exercisable at any time after the date of issuance. The exercise price and the number of Pre-Funded Warrant Shares are subject to appropriate adjustment in the event of certain share dividends and distributions, share splits, share combinations, reclassifications or similar events affecting the Common Shares as well as upon any distribution of assets, including cash, securities or other property, to the Company’s shareholders. The Pre-Funded Warrants will not expire and are exercisable in cash or by means of a cashless exercise. A holder of Pre-Funded Warrants may not exercise such Pre-Funded Warrants if the aggregate number of Common Shares beneficially owned by such holder, together with its affiliates, would exceed more than 4.99% or 9.99% (at the initial election of the holder) of the number of Common Shares outstanding following such exercise, as such percentage ownership is determined in accordance with the terms of the Pre-Funded Warrants. A holder of Pre-Funded Warrants may increase or decrease this percentage not in excess of 19.99% by providing at least 61 days’ prior notice to the Company.

October 2024 Exchange Agreements

On October 17, 2024, the Company entered into exchange agreements (the “Exchange Agreements”) with Commodore Capital Master LP, Deep Track Biotechnology Master Fund, LTD and certain other investors (collectively, the “Holders”) pursuant to which the Holders exchanged an aggregate of 8,325,000 Common Shares for pre-funded warrants to purchase an aggregate of 8,325,000 Common Shares with an exercise price of $0.001 per share. Such Common Shares were retired upon exchange. The exchange

transactions represented offsetting increases and decreases with additional paid-in capital that had no overall impact to the Company’s financial statements.

October 2025 Offering

Subsequent to the quarter ended September 30, 2025, on October 29, 2025, the Company entered into an underwriting agreement (the “Underwriting Agreement”) with Jefferies LLC, Leerink Partners LLC and Evercore Group L.L.C., as representatives of the several underwriters named therein (the “Underwriters”), in connection with an underwritten public offering (the “October 2025 Offering”) of 18,375,000 Common Shares, at an offering price of $12.25 per Common Share, less underwriting discounts and commissions. In addition, under the terms of the Underwriting Agreement, the Company granted the Underwriters an option, exercisable for 30 days, to purchase up to an additional 2,756,250 Common Shares at the same price, which was exercised by the Underwriters in full on October 30, 2025.

The gross proceeds to the Company from the October 2025 Offering, including the full exercise by the Underwriters of their option to purchase additional Common Shares, were approximately $258.9 million. Net proceeds were approximately $242.8 million, after deducting underwriting discounts and commissions and other estimated offering expenses payable by the Company. The October 2025 Offering closed on October 31, 2025.

The Company intends to use the net proceeds from the October 2025 Offering to fund the research and development of its product candidates and working capital and general corporate purposes. The Company may also use a portion of the net proceeds to invest in or acquire additional businesses or compounds that the Company believe are complementary to its own, although the Company has no current plans, commitments or agreements with respect to any future acquisitions.

WARRANTS

2022 USD Financing Warrants

On September 30, 2022, the Company closed an underwritten public offering of 7,058,823 Common Shares and accompanying 2022 USD Financing Warrants to purchase 7,058,823 Common Shares. Each 2022 USD Financing Warrant is immediately exercisable for one Common Share at an initial exercise price of $4.25 per Common Share, subject to certain adjustments, and will expire on September 30, 2027.

The table below represents the activity associated with the Company's outstanding liability-classified 2022 USD Financing Warrants for the nine months ended September 30, 2025.


	2022 USD Financing Warrants
Balance at December 31, 2024		5,086,300
Issued		—
Exercised		(586,346	)
Expired		—
Balance at September 30, 2025		4,499,954

The 2022 USD Financing Warrants are liability-classified. Accordingly, the 2022 USD Financing Warrants are recognized at fair value upon issuance and are adjusted to fair value at the end of each reporting period. Any change in fair value is recognized on the condensed consolidated statements of operations and comprehensive loss.

The below table summarizes the activity of the outstanding liability for the 2022 USD Financing Warrants for the nine months ended September 30, 2025 (in thousands):


	As of September 30, 2025
Balance at December 31, 2024	$	24,010
Warrant exercise		(3,509	)
Change in fair value of the warrant liability		17,774
Balance at September 30, 2025	$	38,275

STOCK-BASED COMPENSATION

Prior to March 14, 2025, the Company was authorized to issue a number of equity awards equal to 15% of the Company’s issued and outstanding Common Shares under the terms of the MindMed Stock Option Plan (the “Stock Option Plan”), together with Common Shares that were issuable pursuant to outstanding awards or grants under any other compensation or incentive mechanism involving the issuance or potential issuance of Common Shares, including the MindMed Performance and Restricted Share Unit Plan (the “PRSU Plan”) and ESPP. The Stock Option Plan and the PRSU Plan were retired effective March 14, 2025, and no further grants will be made under the Stock Option Plan or the PRSU Plan. With the retirement of the Stock Option Plan and the PRSU Plan, the ESPP and any other compensation or incentive mechanism involving the issuance or potential issuance of Common Shares (including inducement grants made outside a plan) are no longer subject to the 15% cap from the Stock Option Plan and PRSU Plan.

In June 2025, the Company adopted the 2025 Equity Incentive Plan (the “2025 Plan”), consisting of (a) 4,500,000 Common Shares reserved for issuance under the 2025 Plan, and (b) a maximum of 9,318,090 Common Shares (the “Outstanding Award Shares”) consisting of (i) an aggregate of 3,500,979 Common Shares that were subject to outstanding option awards under the Stock Option Plan and (ii) an aggregate of 5,817,111 Common Shares subject to outstanding restricted stock unit ("RSU") awards and performance share unit ("PSU") awards under the PRSU Plan. The Outstanding Award Shares will become available for issuance under the 2025 Plan if and as such awards under the Stock Option Plan and the PRSU are forfeited or otherwise terminated. As of September 30, 2025, 375,935 stock options and no RSUs have been granted under the 2025 Plan.

The Company also grants inducement equity awards consisting of stock options, RSUs or PSUs to newly hired employees as an inducement material to the employees entering into employment with the Company in accordance with NASDAQ Listing Rule 5635(c)(4). All such inducement grants are granted outside of the Company’s equity incentive plans and are approved by the Compensation Committee of the Company’s Board of Directors prior to issuance. During the nine months ended September 30, 2025, the Company issued inducement grants consisting of 2,025,950 stock options and 284,500 PSUs. As of September 30, 2025, there were an aggregate of 3,071,450 inducement awards outstanding consisting of (i) 2,726,950 stock options, (ii) 60,000 RSUs and (iii) 284,500 PSUs.

Stock Options

The following table summarizes the Company’s stock option activity for the nine months ended September 30, 2025:


	Number of Options			Weighted Average Exercise Price		Weighted Average Remaining Contractual Life (Years)		Aggregate Intrinsic Value (USD$)
Options outstanding at December 31, 2024		4,225,032		$	12.35		6.6	$	4,147,893
Granted		2,718,435			7.66
Exercised		(273,967	)		4.85
Forfeited		(501,252	)		6.78
Expired		(264,057	)		17.81
Options outstanding at September 30, 2025		5,904,191		$	10.76		7.7	$	23,631,942
Options vested and exercisable at September 30, 2025		1,887,821		$	18.06		4.6	$	5,456,817

The expense recognized related to options during the three months ended September 30, 2025 and 2024 was $2.2 million and $1.9 million, respectively, and $5.4 million and $6.2 million for the nine months ended September 30, 2025 and 2024, respectively.

Restricted Share Units

The following table summarizes the Company's RSU activity for the nine months ended September 30, 2025:



	Number of RSUs			Weighted Average Grant Date Fair Value
Balance at December 31, 2024		1,371,266		$	6.35
Granted		5,343,500			6.43
Vested		(638,158	)		8.07
Cancelled		(284,612	)		5.61
Balance at September 30, 2025		5,791,996		$	6.27

During the nine months ended September 30, 2025, RSUs granted include 2,007,500 PSUs that vest based on the achievement of certain clinical milestones and require service for 36 months after grant. As of September 30, 2025, the Company has determined that all of these milestones are probable of achievement, which means that the PSUs would vest at 200% or a total of 4,015,000 PSUs, which is included in "Granted" in the table above. The Company will recognize the related compensation expense for awards that are probable of vesting over the 36 month requisite service period.

The expense recognized related to RSUs during the three months ended September 30, 2025 and 2024 was $3.5 million and $2.0 million, respectively, and $8.9 million and $6.8 million for the nine months ended September 30, 2025 and 2024, respectively.

Employee Share Purchase Plan

In August 2024, the Company commenced the first offering under the ESPP. Subsequent to this offering, new offerings under the ESPP will commence automatically every nine months until the earlier of (i) termination or modification by the Compensation Committee of the Company’s Board of Directors and (ii) such time when all Common Shares reserved under the ESPP have been issued. During the nine months ended September 30, 2025, the Company recognized $0.2 million of expense in relation to its ESPP and issued 66,165 Common Shares under the ESPP.

Stock-based Compensation Expense

Stock-based compensation expense for all equity arrangements for the three and nine months ended September 30, 2025 and 2024 was as follows (in thousands):


	Three Months Ended September 30,				Nine Months Ended September 30,
	2025		2024		2025		2024
Research and development	$	2,226	$	1,110	$	6,580	$	4,747
General and administrative		3,590		2,731		7,915		8,213
Total	$	5,816	$	3,841	$	14,495	$	12,960

As of September 30, 2025, there was approximately $20.6 million of total unrecognized stock-based compensation expense, related to unvested options granted to employees and directors under the Stock Option Plan that is expected to be recognized over a weighted average period of 3.1 years. As of September 30, 2025, there was approximately $31.2 million of total unrecognized stock-based compensation expense, related to RSUs granted to employees under the PRSU Plan that is expected to be recognized over a weighted average period of 2.6 years.

Directors' Deferred Share Unit Plan

On April 16, 2021, the Company adopted the MindMed Director’s Deferred Share Unit Plan (the “DDSU Plan”). The DDSU Plan sets out a framework to grant non-employee directors DDSUs, which are cash settled awards. The DDSUs generally vest ratably over twelve months after grant and are settled within 90 days of the date the director ceases service to the Company. For the three and nine months ended September 30, 2025, $0.9 million and $1.0 million, respectively, of stock-based compensation expense was recognized relating to the revaluation of the vested DDSUs, and recorded in general and administrative expense in the accompanying condensed consolidated statements of operations and comprehensive loss. For the three months ended September 30, 2024, a decrease of $0.1 million in stock-based compensation expense was recognized relating to the revaluation of the vested DDSUs. For the nine months ended September 30, 2024, $0.5 million of stock-based compensation expense was recognized relating to the revaluation of the vested DDSUs.

During the nine months ended September 30, 2025, the Company did not issue any additional DDSUs. There were 195,743 DDSUs vested as of September 30, 2025. The liability associated with the outstanding vested DDSU’s was $2.2 million as of September 30, 2025, and was recorded to accrued expenses in the accompanying condensed consolidated balance sheets.

To conform with the current year presentation, certain prior year amounts related to DDSUs expense have been reclassified and separately presented from stock-based compensation on the statement of cash flows.

10.

COMMITMENTS AND CONTINGENCIES

As of September 30, 2025, the Company had obligations to make future payments, representing significant research and development contracts and other commitments that are known and committed in the amount of approximately $105.1 million. Most of these agreements are cancelable by the Company with notice. These commitments include agreements related to the conduct of the Company's clinical trials, sponsored research, manufacturing and preclinical studies.

The Company enters into research, development and license agreements in the ordinary course of business where the Company receives research services and rights to proprietary technologies. Milestone and royalty payments that may become due under various agreements are dependent on, among other factors, clinical trials, regulatory approvals and ultimately the successful development of a new drug, the outcome and timing of which are uncertain.

The Company periodically enters into research and license agreements with third parties that include indemnification provisions customary in the industry. These guarantees generally require the Company to compensate the other party for certain damages and costs incurred as a result of claims arising from research and development activities undertaken by or on behalf of the Company. In some cases, the maximum potential amount of future payments that could be required under these indemnification provisions could be unlimited. These indemnification provisions generally survive termination of the underlying agreement. The nature of the indemnification obligations prevents the Company from making a reasonable estimate of the maximum potential amount it could be required to pay. Historically, the Company has not made any indemnification payments under such agreements and no amount has been accrued in the unaudited condensed consolidated financial statements with respect to these indemnification obligations.

During April 2022, the Company entered into a three-year operating lease for office space located in North Carolina with an expiration date of September 30, 2025. Total lease payments under the lease amounted to approximately $0.2 million. In June 2025, the Company amended the lease. The lease amendment extends the lease term from September 30, 2025 to February 1, 2031, and grants the Company additional space. The Company has rent abatement for the first 5 months of the new lease amendment. Total lease payments under the amended lease are expected to amount to approximately $0.9 million. In June 2025, a right-of-use asset and corresponding lease liability for $0.6 million were recorded on the accompanying condensed consolidated balance sheet. The right-of-use asset is recorded in other non-current assets in the accompanying condensed consolidated balance sheet. The current portion of the lease liability is recorded in accrued expenses and the noncurrent portion is recorded in other non-current liabilities in the accompanying condensed consolidated balance sheet. The incremental borrowing rate utilized in the determination of the lease liability was 10.25%.

11.

CREDIT FACILITY

On August 11, 2023, the Company and certain of its subsidiaries party thereto, as co-borrowers (together with the Company, the “Borrowers”) entered into a Loan and Security Agreement (the “Loan Agreement”) with K2 HealthVentures LLC (“K2HV”), as administrative agent and Canadian collateral agent for lenders thereunder (K2HV, together with any other lender from time to time, the "Lenders"), and Ankura Trust Company, LLC, as collateral trustee for the Lenders, providing for an aggregate principal amount of term loans of up to $50.0 million (the “Term Loans”).

On April 18, 2025 (the “Effective Date”), the Borrowers, entered into the First Amendment to the Loan Agreement with K2HV (as amended by the First Amendment, the “Amended Loan Agreement”).

The Amended Loan Agreement provides for, among other things: (i) an aggregate principal amount of term loans (the “Amendment Term Loans”) of up to $120.0 million, consisting of (A) a new Restatement First Tranche Term Loan (as defined in the Amended Loan Agreement) of $42.0 million, which was funded on the Effective Date, a portion of the proceeds of which was used on the Effective Date to refinance in full all Term Loans outstanding under the Loan Agreement, and to pay fees and expenses in connection with the Amended Loan Agreement and the refinancing of the existing Term Loans, (B) subsequent tranches of Amendment Term Loans totaling up to $28.0 million, subject to the occurrence of certain time-based clinical and regulatory milestones and (C) an additional tranche of Amendment Term Loans of up to $50.0 million upon the Company’s request, subject to review by the Lenders of certain information from the Company and discretionary approval by the Lenders, (ii) to the extent any Amendment Term Loans other than the Restatement First Tranche Term Loans are made during the term of the Amended Loan Agreement, a minimum liquidity covenant, beginning on the earlier to occur of (x) July 1, 2026 (which may be extended to July 1, 2027 to the extent the Company has achieved certain fundraising milestones) and (y) the date on which certain clinical and regulatory milestones are not achieved, which covenant shall be waived in any period where the Company’s market capitalization exceeds $500.0 million, (iii) a decrease in the interest rate applicable to all Amendment Term Loans under the Amended Loan Agreement to the greater of (x) 10.25% and (y) the sum of (a) the Prime Rate as reported in The Wall Street Journal plus (b) 2.75% per annum, and (iv) a conversion right at the election of the Lenders at any time following the Effective Date and prior to the full repayment of the Amendment Term Loans to convert up to $7.0 million of the outstanding Amendment Term Loans into the Company’s common

shares (the “Amendment Conversion Shares”), at conversion prices ranging from $4.01 per Amendment Conversion Share to $9.00 per Amendment Conversion Share.

On July 22, 2025, under the terms of the Amended Loan Agreement, K2HV converted $1.0 million of the outstanding Amendment Term Loans into 249,377 Common Shares. As of September 30, 2025, K2HV may convert up to an additional $6.0 million of the outstanding Amendment Term Loans into Common Shares at conversion prices ranging from $7.02 per Amendment Conversion Share to $9.00 per Amendment Conversion Share.

The Amendment Term Loans mature on April 1, 2029, provided that upon the occurrence of certain events the maturity date may be extended to October 1, 2029. The obligations of the Borrowers under the Amended Loan Agreement are secured by substantially all of the assets of the Borrowers, excluding intellectual property. Other than as described above, the proceeds of borrowings under the Amended Loan Agreement are expected to be used for working capital and other general corporate purposes and/or to further support commercial activities and/or business development opportunities. Once repaid, the Amendment Term Loans may not be reborrowed. The Company was in compliance with the Amended Loan Agreement as of September 30, 2025.

In accordance with Financial Accounting Standards Board Accounting Standards Codification Topic 470-50, Debt Modifications and Extinguishments, the Company evaluated the Amended Loan Agreement to determine whether it should be accounted for as a modification or extinguishment. As a result of this analysis, the Amended Loan Agreement was accounted for as a modification and no gain or loss was recognized. Transaction costs incurred from or paid on behalf of K2HV of approximately $0.4 million were capitalized as a deferred debt discount and will be amortized over the term of the Amended Loan Agreement. Transaction costs incurred with third parties directly relating to the Amended Loan Agreement were expensed as incurred.

The Company recorded $1.3 million and $4.2 million in interest expense for the three and nine months ended September 30, 2025, respectively. The expense for the nine months ended September 30, 2025 included a $1.7 million final payment in connection with the Amended Loan Agreement and the refinancing of the existing Term Loans.

Future expected repayments of the principal amount due on the credit facility as of September 30, 2025 were as follows (in thousands):


Remainder of 2025	$	—
2026		—
2027		12,706
2028		20,785
2029		7,508
Total principal repayments		40,999
Unamortized debt issuance costs		(877	)
Accrued final payment fee		263
Total credit facility, non-current, net	$	40,385

As of September 30, 2025, the Company estimated the fair value of the credit facility to be $47.2 million, assuming $6.0 million of principal (the amount of Conversion Shares in-the-money as of September 30, 2025) is converted into Conversion Shares.

12. SEGMENT REPORTING

The Company has one reportable segment related to the research and development of the Company’s product candidates.

The Company’s Chief Operating Decision Maker (the “CODM”), its Chief Executive Officer, reviews the Company’s operations, including reviewing budgets and trial-related data, and decides how to allocate resources and assess performance. When evaluating the Company’s financial performance, the CODM regularly reviews total expenses and total assets and the CODM makes decisions using this information on a consolidated basis. The CODM uses consolidated net income or loss as a measure of profit or loss in allocating resources and assessing segment performance. In addition to the expense categories included within net income

presented on the Company's unaudited condensed consolidated statements of operations and comprehensive loss, see below for additional expense details that are routinely reviewed by the CODM (in thousands):


	Three Months Ended September 30,				Nine Months Ended September 30,
	2025		2024		2025		2024
Research and development:
Internal expenses	$	8,291	$	5,754	$	23,888	$	17,501
External expenses		22,687		11,434		60,256		26,037
Total		30,978		17,188		84,144		43,538
General and administrative:

Large accelerated filer

Accelerated filer

Non-accelerated filer

Smaller reporting company

Emerging growth company

Mind Medicine (MindMed) Inc. 10-Q