UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549

FORM 8-K

CURRENT REPORT

Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

Date of Report (Date of earliest event reported): ~~September~~November 0513, 2025

Sera Prognostics, Inc.

(Exact name of Registrant as Specified in Its Charter)


Delaware	001-40606	26-1911522
(State or Other Jurisdiction of Incorporation)	(Commission File Number)	(IRS Employer Identification No.)

2749 East Parleys Way Suite 200
Salt Lake City, Utah		84109
(Address of Principal Executive Offices)		(Zip Code)

     Registrant’s Telephone Number, Including Area Code: (801) 990-0520

    

     Not Applicable

    

(Former Name or Former Address, if Changed Since Last Report)

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

☐Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

☐Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

☐Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

☐Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Securities registered pursuant to Section 12(b) of the Act:


Title of each class	Trading Symbol(s)	Name of each exchange on which registered
Class A Common Stock, $0.0001 par value per share	SERA	The Nasdaq Stock Market LLC

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§ 230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§ 240.12b-2 of this chapter).

Emerging growth company ☒

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐

Item 72.0102 RegulationResults FDof DisclosureOperations and Financial Condition.

On ~~September~~November 513, 2025, Sera Prognostics, Inc. ~~(the~~issued ~~“Company”) posted~~ a ~~new~~press ~~investor~~release ~~presentation~~announcing to its ~~corporate~~financial ~~website.~~results ~~This~~for ~~presentation was also shared at~~ the ~~H.C.~~third ~~Wainwright~~quarter ~~27th~~ended ~~Annual Global Investment Conference on~~ September 530, 2025 atand 7providing ~~a.m.~~business EThighlights. AThe ~~copy~~full text of the ~~investor~~press ~~presentation~~release is ~~filed~~furnished as Exhibit 99.1 ~~hereto~~to ~~and~~this ~~incorporated~~Current byReport ~~reference~~on ~~herein~~Form 8-K.

The information ~~contained~~ in ~~Item~~this ~~7.01,~~Current Report on Form 8-K (including Exhibit 99.1) ~~furnished herewith,~~ shall not be deemed to be “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), or otherwise subject to the liabilities ~~under~~of that section, nor shall it be deemed incorporated by reference ~~into~~in any registration statement or other document pursuant to the Securities Act of 1933, as amended, or into any filing or other document pursuant to the Exchange Act, except to the extent required by applicable law or regulation or as shall be expressly set forth by specific reference in such filing.

Item 9.01 Financial Statements and Exhibits.

(d) Exhibits

Exhibit Number		Description
99.1		~~Investor~~Press ~~presentation~~release todated beNovember ~~posted on September 5~~13, 2025.
104		Cover Page Interactive Data File (embedded within the Inline XBRL document).

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

			SERA PROGNOSTICS, INC.
Date:	~~September~~November 513, 2025	By:	/s/ Austin Aerts
			Austin AertsChief Financial Officer

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