$PSNL·8-K

Personalis, Inc. · May 20, 4:04 PM ET

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Personalis, Inc. 8-K

Research Summary

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Personalis, Inc. Announces Medicare Coverage Expansion for NeXT Personal Test

What Happened
Personalis, Inc. announced in an 8-K filed May 20, 2026 that on May 19, 2026 the Centers for Medicare & Medicaid Services (CMS) Molecular Diagnostics Program expanded Medicare coverage for the company's ultrasensitive NeXT Personal® test. The coverage expansion applies to monitoring treatment response to neoadjuvant therapy (NAT) in patients diagnosed with Stage II–III Triple-Negative Breast Cancer (TNBC) or HER2-positive (HER2+) breast cancer.

Key Details

  • Filing: Form 8-K (Item 8.01 Other Events) filed May 20, 2026.
  • CMS action date: May 19, 2026 (Molecular Diagnostics Program decision).
  • Test: NeXT Personal® ultrasensitive assay.
  • New covered use: Monitoring treatment response to neoadjuvant therapy in Stage II–III TNBC and HER2+ breast cancer patients.

Why It Matters
Medicare coverage decisions determine reimbursement pathways and influence patient access and clinical adoption. This CMS expansion formally extends Medicare coverage for a specific clinical use of Personalis’s NeXT Personal test, which is a material commercial and regulatory development disclosed to investors.

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