DREWS JURGEN 4

4 · HUMAN GENOME SCIENCES INC · Filed Jun 30, 2010

Insider Transaction Report

Form 4

Period: 2010-06-28

HUMAN GENOME SCIENCES INCHGSI

DREWS JURGEN

Director

Transactions

Exercise/Conversion
Common Stock
2010-06-28$11.51/sh+16,000$184,160→ 26,041 total
Exercise/Conversion
Common Stock
2010-06-28$11.33/sh+1,100$12,463→ 47,675 total
Sale
Common Stock
2010-06-28$24.17/sh−14,900$360,145→ 26,041 total
Exercise/Conversion
Common Stock
2010-06-28$11.33/sh+14,900$168,817→ 40,941 total
Exercise/Conversion
Common Stock
2010-06-29$10.70/sh+10,366$110,916→ 47,675 total
Exercise/Conversion
Non-Employee Director Stock Option - Right to Buy
2010-06-28−16,000→ 0 total
Exercise: $11.51Exp: 2015-05-26→ Common Stock (16,000 underlying)
Exercise/Conversion
Non-Employee Director Stock Option - Right to Buy
2010-06-28−14,900→ 0 total
Exercise: $11.33Exp: 2016-04-27→ Common Stock (14,900 underlying)
Exercise/Conversion
Non-Employee Director Stock Option - Right to Buy
2010-06-29−27,268→ 20,732 total
Exercise: $10.69Exp: 2014-05-21→ Common Stock (27,268 underlying)
Sale
Common Stock
2010-06-28$23.56/sh−1,100$25,915→ 46,575 total
Sale
Common Stock
2010-06-28$23.59/sh−16,000$377,437→ 10,041 total
Exercise/Conversion
Common Stock
2010-06-29$10.69/sh+27,268$291,495→ 37,309 total
Sale
Common Stock
2010-06-29$22.88/sh−10,366$237,126→ 37,309 total
Sale
Common Stock
2010-06-29$22.80/sh−27,268$621,604→ 10,041 total
Exercise/Conversion
Non-Employee Director Stock Option - Right to Buy
2010-06-28−1,100→ 14,900 total
Exercise: $11.33Exp: 2016-04-27→ Common Stock (1,100 underlying)
Exercise/Conversion
Non-Employee Director Stock Option - Right to Buy
2010-06-28−5,634→ 10,366 total
Exercise: $10.70Exp: 2017-05-03→ Common Stock (5,634 underlying)
Exercise/Conversion
Non-Employee Director Stock Option - Right to Buy
2010-06-29−10,366→ 0 total
Exercise: $10.70Exp: 2017-05-03→ Common Stock (10,366 underlying)
Exercise/Conversion
Common Stock
2010-06-28$10.70/sh+5,634$60,284→ 46,575 total
Sale
Common Stock
2010-06-28$24.08/sh−5,634$135,642→ 40,941 total

Footnotes (7)

[F1]This transaction was executed in multiple trades at prices ranging from $23.44 to $23.60. The price reported above reflects the weighted average sale price. Upon written request by the Commission staff, the issuer or a security holder of the issuer, full information regarding the number of shares sold at each separate price is available.
[F2]This transaction was executed in multiple trades at prices ranging from $23.98 to $24.38. The price reported above reflects the weighted average sale price. Upon written request by the Commission staff, the issuer or a security holder of the issuer, full information regarding the number of shares sold at each separate price is available.
[F3]This transaction was executed in multiple trades at prices ranging from $23.61 to $24.60. The price reported above reflects the weighted average sale price. Upon written request by the Commission staff, the issuer or a security holder of the issuer, full information regarding the number of shares sold at each separate price is available.
[F4]This transaction was executed in multiple trades at prices ranging from $23.41 to $23.75. The price reported above reflects the weighted average sale price. Upon written request by the Commission staff, the issuer or a security holder of the issuer, full information regarding the number of shares sold at each separate price is available.
[F5]This transaction was executed in multiple trades at prices ranging from $22.67 to $22.92. The price reported above reflects the weighted average sale price. Upon written request by the Commission staff, the issuer or a security holder of the issuer, full information regarding the number of shares sold at each separate price is available.
[F6]This transaction was executed in multiple trades at prices ranging from $22.69 to $22.91. The price reported above reflects the weighted average sale price. Upon written request by the Commission staff, the issuer or a security holder of the issuer, full information regarding the number of shares sold at each separate price is available.
[F7]These options have vested and are fully exercisable.

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