BIOSITE INC 4

4 · BIOSITE INC · Filed May 26, 2005

Insider Transaction Report

Form 4

Period: 2005-05-25

BIOSITE INCBSTE

WATLINGTON THOMAS M

EVP & COO

Transactions

Exercise/Conversion
Common Stock
2005-05-25$5.50/sh+5,287$29,079→ 5,937 total
Sale
Common Stock
[F1]
2005-05-25$65.00/sh−5,287$343,655→ 650 total
Exercise/Conversion
Common Stock
2005-05-25$10.00/sh+1,000$10,000→ 1,650 total
Sale
Common Stock
[F1]
2005-05-25$65.12/sh−1,000$65,117→ 650 total
Exercise/Conversion
Common Stock
2005-05-25$10.00/sh+1,000$10,000→ 1,650 total
Sale
Common Stock
[F1]
2005-05-25$65.11/sh−1,000$65,114→ 650 total
Exercise/Conversion
Common Stock
2005-05-25$10.00/sh+1,000$10,000→ 1,650 total
Sale
Common Stock
[F1]
2005-05-25$65.08/sh−1,000$65,080→ 650 total
Exercise/Conversion
Common Stock
2005-05-25$10.00/sh+1,000$10,000→ 1,650 total
Sale
Common Stock
[F1]
2005-05-25$65.08/sh−1,000$65,075→ 650 total
Exercise/Conversion
Common Stock
2005-05-25$10.00/sh+1,000$10,000→ 1,650 total
Sale
Common Stock
[F1]
2005-05-25$65.07/sh−1,000$65,068→ 650 total
Exercise/Conversion
Common Stock
2005-05-25$10.00/sh+1,000$10,000→ 1,650 total
Sale
Common Stock
[F1]
2005-05-25$65.04/sh−1,000$65,043→ 650 total
Exercise/Conversion
Common Stock
2005-05-25$10.00/sh+1,000$10,000→ 1,650 total
Sale
Common Stock
[F1]
2005-05-25$65.04/sh−1,000$65,035→ 650 total
Exercise/Conversion
Common Stock
2005-05-25$10.00/sh+1,000$10,000→ 1,650 total
Sale
Common Stock
[F1]
2005-05-25$65.03/sh−1,000$65,030→ 650 total
Exercise/Conversion
Common Stock
2005-05-25$10.00/sh+1,000$10,000→ 1,650 total
Sale
Common Stock
[F1]
2005-05-25$65.03/sh−1,000$65,028→ 650 total
Exercise/Conversion
Common Stock
2005-05-25$10.00/sh+1,000$10,000→ 1,650 total
Sale
Common Stock
[F1]
2005-05-25$65.01/sh−1,000$65,014→ 650 total
Exercise/Conversion
Common Stock
2005-05-25$10.00/sh+5,000$50,000→ 5,650 total
Sale
Common Stock
[F1]
2005-05-25$65.00/sh−5,000$325,000→ 650 total
Exercise/Conversion
Incentive Stock Option (right to buy)
[F2]
2005-05-25$65.00/sh−5,287$343,655→ 0 total
Exercise: $5.50From: 1996-12-05Exp: 2006-12-05→ Common Stock (5,287 underlying)
Exercise/Conversion
Non-Qualified Stock Option (right to buy)
[F2]
2005-05-25$65.12/sh−1,000$65,117→ 40,227 total
Exercise: $10.00From: 1999-06-09Exp: 2009-06-09→ Common Stock (1,000 underlying)
Exercise/Conversion
Non-Qualified Stock Option (right to buy)
[F2]
2005-05-25$65.11/sh−1,000$65,114→ 39,227 total
Exercise: $10.00From: 1999-06-09Exp: 2009-06-09→ Common Stock (1,000 underlying)
Exercise/Conversion
Non-Qualified Stock Option (right to buy)
[F2]
2005-05-25$65.08/sh−1,000$65,080→ 38,227 total
Exercise: $10.00From: 1999-06-09Exp: 2009-06-09→ Common Stock (1,000 underlying)
Exercise/Conversion
Non-Qualified Stock Option (right to buy)
[F2]
2005-05-25$65.08/sh−1,000$65,075→ 37,227 total
Exercise: $10.00From: 1999-06-09Exp: 2009-06-09→ Common Stock (1,000 underlying)
Exercise/Conversion
Non-Qualified Stock Option (right to buy)
[F2]
2005-05-25$65.07/sh−1,000$65,068→ 36,227 total
Exercise: $10.00From: 1999-06-09Exp: 2009-06-09→ Common Stock (1,000 underlying)
Exercise/Conversion
Non-Qualified Stock Option (right to buy)
[F2]
2005-05-25$65.04/sh−1,000$65,043→ 35,227 total
Exercise: $10.00From: 1999-06-09Exp: 2009-06-09→ Common Stock (1,000 underlying)
Exercise/Conversion
Non-Qualified Stock Option (right to buy)
[F2]
2005-05-25$65.04/sh−1,000$65,035→ 34,227 total
Exercise: $10.00From: 1999-06-09Exp: 2009-06-09→ Common Stock (1,000 underlying)
Exercise/Conversion
Non-Qualified Stock Option (right to buy)
[F2]
2005-05-25$65.03/sh−1,000$65,030→ 33,227 total
Exercise: $10.00From: 1999-06-09Exp: 2009-06-09→ Common Stock (1,000 underlying)
Exercise/Conversion
Non-Qualified Stock Option (right to buy)
[F2]
2005-05-25$65.03/sh−1,000$65,028→ 32,227 total
Exercise: $10.00From: 1999-06-09Exp: 2009-06-09→ Common Stock (1,000 underlying)
Exercise/Conversion
Non-Qualified Stock Option (right to buy)
[F2]
2005-05-25$65.01/sh−1,000$65,014→ 31,227 total
Exercise: $10.00From: 1999-06-09Exp: 2009-06-09→ Common Stock (1,000 underlying)
Exercise/Conversion
Non-Qualified Stock Option (right to buy)
[F2]
2005-05-25$65.00/sh−5,000$325,000→ 26,227 total
Exercise: $10.00From: 1999-06-09Exp: 2009-06-09→ Common Stock (5,000 underlying)

Footnotes (2)

[F1]The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 2, 2005.
[F2]Option vests daily over a four-year period commencing on the date of grant, except that no options are exercisable for the first six months after the date of grant.

Signature

By: Robyn Shutak For: Thomas M. Watlington|2005-05-26

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