Washburn Theodore James Jr. 4

4 · AGIOS PHARMACEUTICALS, INC. · Filed Mar 3, 2026

Insider Transaction Report

Form 4

Period: 2026-03-01

AGIOS PHARMACEUTICALS, INC.AGIO

Washburn Theodore James Jr.

Principal Accounting Officer

Transactions

Exercise/Conversion
Common stock
[F1]
2026-03-02+2,350→ 3,293 total
Sale
Common stock
[F2]
2026-03-02$28.96/sh−698$20,214→ 2,595 total
Exercise/Conversion
Common stock
2026-03-02+2,450→ 4,970 total
Sale
Common stock
[F3]
2026-03-02$28.96/sh−727$21,054→ 4,243 total
Exercise/Conversion
Common stock
2026-03-02+2,695→ 6,938 total
Sale
Common stock
[F4]
2026-03-02$28.96/sh−798$23,110→ 6,140 total
Award
Restricted stock units
[F5][F6]
2026-03-01+8,452→ 8,452 total
→ Common stock (8,452 underlying)
Exercise/Conversion
Restricted stock units
[F5][F7]
2026-03-02−2,350→ 0 total
→ Common stock (2,350 underlying)
Exercise/Conversion
Restricted stock units
[F5][F8]
2026-03-02−2,450→ 2,450 total
→ Common stock (2,450 underlying)
Exercise/Conversion
Restricted stock units
[F5][F9]
2026-03-02−2,695→ 5,390 total
→ Common stock (2,695 underlying)

Footnotes (9)

[F1]Includes 75 shares purchased through the Company's employee stock purchase plan.
[F2]Shares sold to cover the tax withholding obligation in respect of vesting of the reporting person's restricted stock units. This transaction was effected pursuant to durable automatic sale instructions consistent with the affirmative defense to liability under Section 10(b) of the Securities Exchange Act of 1934 under Rule 10b5-1(c) promulgated under such Act. Such instructions were included in the reporting person's restricted stock unit agreement dated March 1, 2023.
[F3]Shares sold to cover the tax withholding obligation in respect of vesting of the reporting person's restricted stock units. This transaction was effected pursuant to durable automatic sale instructions consistent with the affirmative defense to liability under Section 10(b) of the Securities Exchange Act of 1934 under Rule 10b5-1(c) promulgated under such Act. Such instructions were included in the reporting person's restricted stock unit agreement dated March 1, 2024.
[F4]Shares sold to cover the tax withholding obligation in respect of vesting of the reporting person's restricted stock units. This transaction was effected pursuant to durable automatic sale instructions consistent with the affirmative defense to liability under Section 10(b) of the Securities Exchange Act of 1934 under Rule 10b5-1(c) promulgated under such Act. Such instructions were included in the reporting person's restricted stock unit agreement dated March 1, 2025.
[F5]Each restricted stock unit represents a contingent right to receive one share of the issuer's common stock.
[F6]The restricted stock units were granted on March 1, 2026. Beginning on March 1, 2027, the shares underlying the restricted stock units will vest in three equal annual installments.
[F7]The restricted stock units were granted on March 1, 2023. Beginning on March 1, 2024, the shares underlying the restricted stock units will vest in three equal annual installments.
[F8]The restricted stock units were granted on March 1, 2024. Beginning on March 1, 2025, the shares underlying the restricted stock units will vest in three equal annual installments.
[F9]The restricted stock units were granted on March 1, 2025. Beginning on March 1, 2026, the shares underlying the restricted stock units will vest in three equal annual installments.

Signature

/s/ William Cook, as attorney-in-fact for Theodore James Jr. Washburn|2026-03-03

Documents

1 file

4
wk-form4_1772572356.xmlPrimary
FORM 4