Opaleye Management Inc. 4

4 · Sol-Gel Technologies Ltd. · Filed Mar 24, 2026

AI-generated summary of this filing

Updated Mar 24, 2026

Sol‑Gel (SLGL) 10% Owner Opaleye Management Buys Shares

What Happened

Opaleye Management Inc., identified as a 10% owner of Sol‑Gel Technologies Ltd. (SLGL), purchased a total of 39,665 shares on 2026-03-24 via open‑market/private purchases (transaction code P). The trades were 34,665 shares at $72.00 ($2,495,880) and 5,000 shares at $72.00 ($360,000), for an aggregate cost of $2,855,880. This was a purchase (buy), which is generally viewed as a positive/accumulation signal rather than a sale.

Key Details

Transaction date: 2026-03-24
Trades: 34,665 shares @ $72.00 = $2,495,880; 5,000 shares @ $72.00 = $360,000; Total = 39,665 shares @ $72.00 = $2,855,880
Transaction type/code: P = Purchase (open market or private purchase)
Shares owned after transaction: Not specified in the provided filing
Filing timeliness: Report filed on 2026-03-24 (same date as the reported transactions)
Footnotes:
- F1/F2 note that these shares are owned directly by investment vehicles (Opaleye, L.P. and a separately managed account) for which Opaleye Management, Inc. is the investment/portfolio manager.
- F3 states Opaleye Management disclaims beneficial ownership except to the extent of its pecuniary interest; the filing is not an admission of beneficial ownership for Section 16(a) purposes.

Context

This filing reports institutional buying by a 10% owner (investment manager) rather than insider trading by an executive; such institutional purchases reflect portfolio-level activity and should be interpreted differently than officer/director trades.
Because these were outright purchases (not option exercises, awards, or gifts), they represent accumulation of shares rather than liquidity transactions.

Form 4

Period: 2026-03-24

10% Owner

Transactions

Purchase
Ordinary Shares, par value NIS 1.00 per share.
[F1][F3]
2026-03-24$72.00/sh+34,665$2,495,880→ 485,000 total(indirect: By Opaleye, L.P.)
Purchase
Ordinary Shares, par value NIS 1.00 per share.
[F2][F3]
2026-03-24$72.00/sh+5,000$360,000→ 15,000 total(indirect: By Managed Account)

Footnotes (3)

[F1]Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Fund.
[F2]Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Managed Account.
[F3]Opaleye Management, Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose.

Signature

Opaleye Management Inc., By: /s/ James Silverman, President|2026-03-24

1 file