Sol-Gel (SLGL) 10% Owner Opaleye Management Buys 1,683 Shares

What Happened
Opaleye Management, Inc., the investment manager to entities that together own more than 10% of Sol-Gel Technologies Ltd. (SLGL), reported two purchases (Form 4) totaling 1,683 shares. On 2026-09-01 it acquired 783 shares at $69.52 each ($54,434), and on 2026-09-02 it acquired 900 shares at a weighted average price of $68.95 each ($62,054). Total reported cash outlay for the two purchases was $116,488. These were purchases (code P), which are generally viewed as a neutral-to-bullish signal compared with routine insider sales.

Key Details

• Transaction dates and prices:
  • 2026-09-01: 783 shares @ $69.52 = $54,434
  • 2026-09-02: 900 shares @ $68.95 (weighted avg; prices ranged $68.94–$68.95) = $62,054
• Total shares acquired: 1,683; total value: $116,488.
• Shares owned after the transaction: not specified in the provided filing excerpt.
• Filing date: 2026-09-03 (no late filing indicated in the materials provided).
• Footnotes of note:
  • F1/F2: Purchases were made by Opaleye-managed vehicles (Opaleye, L.P. and a separately managed account); as manager, Opaleye Management, Inc. may be deemed to beneficially own the securities held by those accounts.
  • F3: The $68.95 price is a weighted average for multiple trades in the narrow $68.94–$68.95 range; detailed per-trade pricing is available upon request to the SEC/issuer.
  • F4: Opaleye Management disclaims beneficial ownership except to the extent of its pecuniary interest (standard institutional disclaimer).

Context
This filing reflects institutional purchases by an investment manager on behalf of client vehicles, not an executive or company insider personally trading company stock. Such buys by 10% owners or their managers show capital deployed by funds/accounts they manage, and are informative but do not necessarily indicate executives’ personal views. The transactions were reported on a Form 4 filed two days after the first purchase.