Sol-Gel (SLGL) 10% Owner Opaleye Management Buys Shares

What Happened
Opaleye Management, Inc., identified as a 10% owner, made two purchases of Sol-Gel Technologies Ltd. (SLGL) common stock (transaction code P). On 2026-09-10 it acquired 1,631 shares at $66.80 for $108,943, and on 2026-09-11 it acquired 1,493 shares at $65.94 for $98,456 — a total of 3,124 shares costing approximately $207,399. These were purchases (accumulation) rather than sales.

Key Details

• Transaction dates and prices:
  • 2026-09-10: Purchased 1,631 shares @ $66.80 = $108,943
  • 2026-09-11: Purchased 1,493 shares @ $65.94 = $98,456
• Total purchased: 3,124 shares for about $207,399.
• Shares owned after the transactions: Not specified in the provided filing.
• Footnotes:
  • F1: Securities reported as owned directly by Opaleye, L.P. (the Fund); Opaleye Management is the Fund’s investment manager and may be deemed to beneficially own those Fund holdings.
  • F2: Some securities are held in a separately managed account for which Opaleye Management is portfolio manager.
  • F3: Opaleye Management disclaims beneficial ownership except to the extent of its pecuniary interest.
• Timeliness: Filing dated 2026-09-14 for transactions on 2026-09-10 — filed within standard Form 4 timing (timely).

Context
This filing reflects institutional buying by a reported 10% owner (investment manager/manager of related funds and accounts), not an executive officer. Purchases by a large holder can indicate accumulation but do not by themselves explain motive; the footnotes make clear Opaleye Management may be reporting holdings managed for funds/accounts and disclaims direct beneficial ownership beyond pecuniary interest. Transaction code P denotes an open-market or private purchase.