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8-KAccepted Oct 13, 9:00 AM ET

Oncotelic Therapeutics: presents PDAOAI platform and HCC research

OTLCOncotelic Therapeutics, Inc.

Accepted (ET)

9:00 AM

Oct 13, 2026

Filed

Oct 13, 2026

Documents

39

Size

8.9 MB

Summary

Oncotelic Therapeutics: presents PDAOAI platform and HCC research

Updated

What happened

  • Oncotelic Therapeutics reported that on Oct 7, 2026 and Oct 8, 2026 representatives presented information at Drug Discovery 2026 in Burlingame, California.
  • The company presented material on its PDAOAI platform and on hepatocellular carcinoma ("HCC") research, including a four-gene mTOR-related signature.

Key details

  • Scott Myers, Product Manager, described the PDAOAI search and evidence-aggregation workflow and an index of approximately 29 million PubMed abstracts using Partitioned Literature Aggregation.
  • Saran Saund, Chief Business Officer, presented a 4-gene mTOR-related signature comprising FKBP1A, EIF4E, RRAGC, and PPARGC1A; the signature was associated with overall survival in an exploratory discovery analysis and an independent Japanese patient cohort.
  • Presentations noted that the retrospective findings do not establish that the signature predicts treatment benefit from everolimus, Sapu003, or other mTOR-directed therapies.
  • The presentations described "BIO REBOOT," an initiative inviting researchers to propose therapeutic research projects using PDAOAI; selected projects may qualify for startup funding and development support, subject to scientific review, available resources, and agreed terms.

Why it may matter

  • Item 8.01 (Other events) was reported; the item covers the furnished presentations and related materials about the PDAOAI platform, HCC research, and the BIO REBOOT initiative.
  • The filing does not show why the insider traded or why the company acted.

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