Gharib Samir M. 4

4 · SPRUCE BIOSCIENCES, INC. · Filed Dec 12, 2025

Form 4

Period: 2025-12-10

PRESIDENT AND CFO

Transactions

Exercise/Conversion
Common Stock
2025-12-10+514→ 6,580 total
Tax Payment
Common Stock
2025-12-10$85.67/sh−184$15,763→ 6,396 total
Exercise/Conversion
Common Stock
2025-12-11+1,900→ 8,296 total
Tax Payment
Common Stock
2025-12-11$88.41/sh−680$60,119→ 7,616 total
Exercise/Conversion
Restricted Stock Units
2025-12-10−514→ 1,539 total
Exercise: $0.00→ Common Stock (514 underlying)
Award
Restricted Stock Units
2025-12-11+7,600→ 7,600 total
Exercise: $0.00→ Common Stock (7,600 underlying)
Exercise/Conversion
Restricted Stock Units
2025-12-11−1,900→ 5,700 total
Exercise: $0.00→ Common Stock (1,900 underlying)

Footnotes (3)

[F1]On March 14, 2024, the Reporting Person was granted a total of 2,053 RSU's. Subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan) as of each such vesting date, 25% of the total number of RSUs vested on December 10, 2025, the first anniversary of the achievement of a specified clinical development objective. 25% of the total number of the RSUs will vest on each of the second, third and fourth anniversaries of such achievement. On December 10, 2025, 514 shares vested and 184 shares were withheld for taxes, resulting in a net issuance of 330 shares.
[F2]Each RSU represents a contingent right to receive one share of SPRB common stock.
[F3]25% of the total number of RSUs vested on grant. 25% of the total number of RSUs will vest on December 15, 2026, December 15, 2027 and December 15, 2028, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan) as of each such vesting date. On December 11, 2025, 1,900 shares vested and 680 shares were withheld for taxes, resulting in a net issuance of 1,220 shares.

Documents

1 file