UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

~~Washington~~WASHINGTON, ~~D.C.~~DC 20549

FORM 8-K

CURRENT REPORT

Pursuant to Section 13 or 15(d) of theSecurities Exchange Act of 1934

~~the~~Date ~~Securities~~of ~~Exchange~~Report ~~Act~~(Date of ~~1934~~earliest event reported): March 28, 2016

Date of Report (Date of earliest event reported): March 14, 2016

Diadexus, Inc.

(Exact ~~name~~Name of Registrant as ~~specified~~Specified in its ~~charter~~Charter)

Delaware	0-26483	94-3236309	~~94-3236309~~
(State or Other Jurisdiction of Incorporation)	(Commission File Number)		(IRS Employer Identification Number)
(State or Other Jurisdictionof Incorporation)	(CommissionFile Number)	(IRS EmployerIdentification No.)
349 Oyster Point Boulevard, South San Francisco, California				94080
349 Oyster Point Boulevard, South San Francisco, California 94080
(Address of Principal Executive Offices)				(Zip Code)
(Address of Principal Executive Offices) (Zip Code)

Registrant’s telephone number, including area code: (650) 246-6400

N/A

(Former Name or Former Address, if Changed Since Last Report.)

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

£o Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

£o Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

£o Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

£o Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Item 5 2.02. ~~Departure~~Results of ~~Directors~~Operations orand ~~Certain~~Financial ~~Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers~~Condition.

~~After~~On ~~adding~~March ~~certain positions within the Research and Development organization and restructuring the Heart Failure program~~28, ~~Dr. Emilia Zychlinksy~~2016, Diadexus, Inc.’s (the “Company”) ~~Executive~~issued ~~Vice~~a ~~President~~press ~~and~~release ~~Chief~~announcing ~~Technical~~financial ~~Officer,~~results ~~notified~~for ~~the~~its ~~Company~~fourth onquarter ~~March~~and ~~14,~~full ~~2016,~~year ~~that~~ended ~~she~~December is31, ~~resigning~~2015. ~~effective~~A ascopy of ~~April~~the 1,final ~~2016.~~press ~~The~~release ~~Company~~is ~~does~~furnished ~~not~~as ~~intend~~Exhibit 99.1 to ~~hire~~this areport, ~~replacement~~which ~~for~~replaced ~~this~~the ~~position~~initial atpress ~~this~~release ~~time.~~issued ~~She~~earlier ~~will~~today. ~~continue~~The inupdated ~~that~~press ~~role~~release ~~until~~corrected the ~~effective~~classification ~~date~~ of ~~her~~three ~~resignation.~~line ~~Dr.~~items ~~Zychlinksy~~on ~~had~~the noCondensed ~~disputes~~Statements orof ~~disagreements~~Operations ~~with~~and the ~~operations,~~Condensed ~~policies~~Balance ~~or practices of the Company~~Sheets.

The information furnished pursuant to this Item 2.02 of this report, including the exhibit attached hereto, shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), or otherwise subject to the liability of that section, nor shall it be deemed incorporated by reference in any filing under the Securities Act of 1933, as amended, or under the Exchange Act, regardless of any general incorporation language in any such filing, unless the Company expressly sets forth in such filing that such information is to be considered “filed” or incorporated by reference therein.

Item 9.01. Financial Statements and Exhibits.

(d) Exhibits.


Exhibit No.		Description

99.1		Press Release dated March 28, 2016 entitled “Updated - Diadexus, Inc. Reports Fourth Quarter and Full Year 2015 Financial Results.”

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

	Diadexus, Inc.
Date: March 17, 2016	By:		/s/ Leone Patterson
Date: March 28, 2016
			Leone Patterson
	By:	/s/ Leone D. Patterson
			Chief Financial Officer
		Leone D. Patterson
		Chief Financial Officer

EXHIBIT INDEX


Exhibit No.		Description

99.1		Press Release dated March 28, 2016 entitled “Diadexus, Inc. Reports Fourth Quarter and Full Year 2015 Financial Results.”

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