UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM 8-K

CURRENT REPORT

~~PURSUANT~~Pursuant TOto ~~SECTION~~Section 13 ORor 15(Dd) ~~OFTHE~~of The Securities Exchange Act of 1934

~~SECURITIES~~Date ~~EXCHANGE~~of ~~ACT~~Report OF(Date ~~1934~~of earliest event reported): May 8, 2025

Date of Report (Date of earliest event reported): April 25, 2025

INTERPACE BIOSCIENCES, INC.

(Exact name of ~~Registrant~~registrant as specified in its charter)

delaware	0-24249	22-2919486
Delaware	0-24249	22-2919486
(State or other jurisdiction of incorporation)	(Commission File Number)	(IRS Employer Identification No.)

Waterview Plaza, Suite 310, 2001 Route 46

~~2001~~Parsippany, ~~Route~~NJ ~~46,~~07054

~~Parsippany~~(Address, including zip code, of principal executive offices)

NJ 07054

(Address, including zip code, of Principal Executive Offices)

(855) 776-6419

Registrant’s telephone number, including area code

~~NotApplicable~~Not Applicable

(Former name or former address, if changed since last report)

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

☐ Written communications pursuant to Rule 425 under the ~~SecuritiesAct~~Securities Act (17 CFR 230.425) ☐ Soliciting material pursuant to Rule 14a-12 under the ~~ExchangeAct~~Exchange Act (17 CFR 240.14a-12) ☐ Pre-commencement communications pursuant to Rule 14d-2(b) under the ~~ExchangeAct~~Exchange Act (17 CFR 240.14d-2(b)) ☐ Pre-commencement communications pursuant to Rule 13e-4(c) under the ~~ExchangeAct~~Exchange Act (17 CFR 240.13e-4(c))

Securities registered pursuant to Section 12(b) of ~~theAct~~the Act:

Title of each class		Trading Symbol(s)		Name of each exchange on which registered
None		N/A		N/A

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule 12b-2 of the Securities ~~ExchangeAct~~Exchange Act of 1934 (§240.12b-2 of this chapter).

☐ Emerging growth company ☐

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the ~~ExchangeAct~~Exchange Act. ☐

Item 2.0502 ~~CostsAssociated~~Results ~~with~~of ~~Exit~~Operations orand ~~DisposalActivities~~Financial Condition.

On ~~April~~May 248, 2025, Interpace Biosciences, Inc. ~~(the “Company”) announced that the Genetic Testing for Oncology (L39365) Local Coverage Determination (“LCD”)~~ issued bya ~~the~~press ~~Medicare~~release ~~Administrative~~announcing ~~Contractor~~its ~~Novitas~~results ~~Solutions~~of ~~will~~operations goand ~~into~~financial ~~effect,~~condition ~~ending reimbursement~~ for the quarter ~~Company’s~~ended ~~PancraGEN®~~March ~~test~~31, 2025. The ~~Centers~~full ~~for~~text ~~Medicare~~of ~~& Medicaid Services delayed implementation by 60 days earlier in~~ the ~~year~~press ~~and~~release ~~confirmed~~is ~~finalization~~set offorth ~~the LCD~~ as ofExhibit ~~April 24, 2025~~99.1 ~~Specimens~~attached ~~for~~hereto ~~first-line fluid chemistry~~ and ~~PancraGEN®~~is ~~testing~~incorporated ~~will not be accepted~~ herein by ~~the Company after May 2, 2025~~reference.

AsThe ainformation ~~result~~in ofItem ~~the~~2.02 ~~established~~of ~~non-coverage~~this ~~for~~Current ~~the~~Report ~~Company’s~~on ~~PancraGEN®~~Form ~~test~~8-K, onincluding ~~April~~Exhibit 2599.1, ~~2025,~~is ~~the~~being ~~Company~~furnished ~~announced~~and ~~implementation of~~shall ~~its~~not ~~previously~~be ~~approved~~deemed ~~restructuring~~“filed” for ~~and~~purposes ~~cost-savings~~of ~~plan~~Section to18 ~~reduce~~of ~~operating~~the ~~costs~~Securities ~~and~~Exchange ~~better~~Act ~~align~~of ~~its~~1934, ~~workforce~~as ~~with~~amended ~~the loss of PancraGEN®~~ (the “~~Restructuring~~Exchange ~~Plan~~Act”)., ~~The~~or ~~Company~~otherwise ~~expects~~subject to the ~~implementation~~liabilities of ~~the~~that ~~Restructuring~~section, ~~Plan~~nor shall it be deemed to be ~~substantially completed~~incorporated by reference in any registration statement or other document filed under the ~~end~~Securities Act of 1933, as amended, or the ~~second~~Exchange ~~quarter~~Act, ofexcept ~~2025~~as otherwise stated in such filing.

Under the Restructuring Plan, the Company is reducing its workforce and impacted employees will be eligible to receive severance benefits. The Company expects to incur severance costs in the range of $0.5 million to $0.6 million to be recorded primarily in the second quarter of 2025 which is in addition to the $0.2 million previously recorded in the first quarter of 2025.

The Company expects that the loss of PancraGEN® and related restructuring activities will reduce its annualized cost of revenue and operating expenses by approximately $12.5 million to $14.5 million which is expected to substantially offset the expected loss of approximately one-third of its revenues. The cost that the Company expects to incur in connection with the Restructuring Plan is subject to several assumptions, and actual results may differ materially. The Company may also incur additional costs not currently contemplated due to events that may occur as a result of, or that are associated with, the Restructuring Plan.

Item 8.01 Other Events.

On April 24, 2025, the Company issued a press release announcing that the Genetic Testing for Oncology (L39365) LCD issued by the Medicare Administrative Contractor Novitas Solutions will go into effect, ending reimbursement for the Company’s PancraGEN® test and that the Company’s Restructuring Plan would be implemented. A copy of the press release is filed as Exhibit 99.1 hereto and incorporated herein by reference.

Item 9.01 Financial Statements and Exhibits.

Exhibit No.		Description
99.1		Press Release, dated April 24, 2025.
104		Cover Page Interactive Data File (embedded within the Inline XBRL document).

(d) Exhibits.

SIGNATURE

Exhibit Number		Description
99.1		Press Release, dated May 8, 2025.
104		Cover Page Interactive Data File (embedded within the Inline XBRL document).

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

~~Interpace~~INTERPACE ~~Biosciences~~BIOSCIENCES, ~~Inc~~INC. By: /s/ Thomas W. Burnell Name: Thomas W. Burnell Title: President and Chief Executive Officer

Date: ~~April~~May 308, 2025

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