UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM 6-K

REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934

For the month of May 2026.

____________________________________

Commission File Number: 001-40627

SOPHiA GENETICS SA

(Exact name of registrant as specified in its charter)

La Pièce 12

CH-1180 Rolle

Switzerland

(Address of principal executive office)

Indicate by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F:

Form 20-F

Form 40-F

SIGNATURE

SOPHiA GENETICS SA (the “Company”) today published its Environmental, Social and Governance Impact Summary as per December 31, 2025 (“2025 ESG Impact Summary”). The 2025 ESG Impact Summary is available on www.sophiagenetics.com, in the Investor Relations section.


		SOPHiA GENETICS SA
Date:	May 19, 2026

		By:	/s/ Daan van Well
		Name:	Daan van Well
		Title:	Chief Legal and Regulatory Officer

EXHIBIT INDEX


Exhibit No.			Description
99.1			2025 ESG Impact Summary

SOPHiA GENETICS SA 6-K