Insider · CIK 0001236365

MANUSO JAMES S J

Reports to the SEC for 4 companies · DURHAM, NC

sec.gov

Transactions

Companies

Filings

CIK

0001236365

Forms 4 and 5

Insider transactions

50 trades

Date	Company	Role	Code	Shares	Price	Value	Shares after
2026-04-20	IRDOpus Genetics, Inc.A Award	Director	AAward	+24.4K sh	—	—	317,318
2026-02-12	HURATuHURA Biosciences, Inc./NV · Options (Right to Buy)A Award	Director	AAward	+156K sh	—	—	156,240
2026-01-01	IRDOpus Genetics, Inc.A Award	Director	AAward	+31.2K sh	—	—	292,951
2025-04-30	IRDOpus Genetics, Inc.A Award	Director	AAward	+79.5K sh	—	—	261,763
2025-04-30	IRDOpus Genetics, Inc. · Stock Option (Right to Buy)A Award	Director	AAward	+79.6K sh	—	—	79,592
2025-01-02	IRDOpus Genetics, Inc.A Award	Director	AAward	+50.2K sh	—	—	182,259
2025-01-02	HURATuHURA Biosciences, Inc./NV · Options (Right to Buy)A Award	Director	AAward	+59.6K sh	—	—	59,590
2024-10-18	HURATuHURA Biosciences, Inc./NV · Options (Right to Buy)A Award	Director	AAward	+13.6K sh	—	—	13,553
2024-10-18	HURATuHURA Biosciences, Inc./NV · Options (Right to Buy)A Award	Director	AAward	+13.6K sh	—	—	13,553
2024-06-11	IRDOpus Genetics, Inc.A Award	Director	AAward	+41.1K sh	—	—	132,037
2024-06-11	IRDOpus Genetics, Inc. · Stock Option (Right to Buy)A Award	Director	AAward	+35.2K sh	—	—	35,181
2024-01-01	IRDOpus Genetics, Inc.A Award	Director	AAward	+22.1K sh	—	—	90,894
2023-06-06	IRDOpus Genetics, Inc.A Award	Director	AAward	+11K sh	—	—	68,804
2023-06-06	IRDOpus Genetics, Inc. · Stock OptionA Award	Director	AAward	+9,639 sh	—	—	9,639
2023-04-19	IRDOpus Genetics, Inc.A Award	Director	AAward	+2,819 sh	—	—	57,828
2023-01-11	IRDOpus Genetics, Inc.A Award	Director	AAward	+18.5K sh	—	—	55,009
2022-10-11	IRDOpus Genetics, Inc.X Exercise of In-Money	Director	XExercise of In-Money	+787 sh	$0.00	+$0.079	36,465
2022-10-11	IRDOpus Genetics, Inc. · Series B Warrant (right to buy)X Exercise of In-Money	Director	XExercise of In-Money	−787 sh	—	—	0
2022-07-01	IRDOpus Genetics, Inc.A Award	Director	AAward	+14.1K sh	—	—	35,678
2022-06-13	IRDOpus Genetics, Inc. · Stock Option (right to buy)A Award	Director	AAward	+20K sh	—	—	20,000
2022-05-20	IRDOpus Genetics, Inc.P Purchase	Director	PPurchase	+5,000 sh	$1.99	+$9,950	21,570
2021-11-18	IRDOpus Genetics, Inc.P Purchase	Director	PPurchase	+2,000 sh	$3.50	+$7,000	16,570
2021-06-07	IRDOpus Genetics, Inc. · Stock Option (right to buy)A Award	Director	AAward	+20K sh	—	—	20,000
2020-11-19	IRDOpus Genetics, Inc.P Purchase	Director	PPurchase	+4,434 sh	—	—	14,570
2020-11-19	IRDOpus Genetics, Inc. · Series A Warrant (right to buy)P Purchase	Director	PPurchase	+6,697 sh	—	—	6,697
2020-11-19	IRDOpus Genetics, Inc. · Series B Warrant (right to buy)P Purchase	Director	PPurchase	+787 sh	—	—	787
2020-11-11	IRDOpus Genetics, Inc. · Stock Option (right to buy)A Award	Director	AAward	+5,000 sh	—	—	5,000
2020-11-05	IRDOpus Genetics, Inc.A Award	Director	AAward	+10.1K sh	—	—	10,136
2020-11-05	IRDOpus Genetics, Inc. · Stock Option (right to buy)A Award	Director	AAward	+35.7K sh	—	—	35,663
2020-11-05	IRDOpus Genetics, Inc. · Stock Option (right to buy)A Award	Director	AAward	+52.8K sh	—	—	52,825
2017-12-09	RespireRx Pharmaceuticals Inc.Common Stock Options (to purchase shares of Common Stock)J Other	Director, President and CEO	JOther	+609K sh	—	—	608,704
2017-09-13	RespireRx Pharmaceuticals Inc.P Purchase	Director, President and CEO	PPurchase	+1,097 sh	—	—	74,252
2017-09-13	RespireRx Pharmaceuticals Inc.Common Stock Warrants (right to buy)P Purchase	Director, President and CEO	PPurchase	+2,195 sh	—	—	2,195
2017-06-30	RespireRx Pharmaceuticals Inc.Common Stock Options (to purchase shares of Common Stock)A Award	Director, President and CEO	AAward	+50K sh	—	—	50,000
2017-01-18	RespireRx Pharmaceuticals Inc.Common Stock Options (to purchase shares of Common Stock)A Award	Director, President and CEO	AAward	+75K sh	—	—	75,000
2016-04-07	RespireRx Pharmaceuticals Inc.J Other	Director, President and CEO	JOther	+11.9M sh	—	—	23,775,558
2016-04-07	RespireRx Pharmaceuticals Inc.Common Stock Warrants (right to buy)J Other	Director, President and CEO	JOther	−23.8M sh	—	—	0
2016-04-07	RespireRx Pharmaceuticals Inc.Common Stock Warrants (right to buy)J Other	Director, President and CEO	JOther	+11.9M sh	—	—	11,887,779
2016-03-31	RespireRx Pharmaceuticals Inc.Common Stock Options (to purchase shares of Common Stock)A Award	Director, President and CEO	AAward	+26.5M sh	—	—	26,500,000
2016-02-04	RespireRx Pharmaceuticals Inc.Common Stock Warrants (right to buy)J Other	Director, President and CEO	JOther	+2.63M sh	—	—	2,630,000
2015-08-28	RespireRx Pharmaceuticals Inc.P Purchase	Director, President and CEO	PPurchase	+11.9M sh	—	—	11,887,779
2015-08-28	RespireRx Pharmaceuticals Inc.Common Stock Warrants (right to buy)P Purchase	Director, President and CEO	PPurchase	+23.8M sh	—	—	23,775,558
2015-08-18	RespireRx Pharmaceuticals Inc.Common Stock Options (to purchase shares of Common Stock)A Award	Director, President and CEO	AAward	+5.08M sh	—	—	5,081,300
2015-08-18	RespireRx Pharmaceuticals Inc.Common Stock Options (to purchase shares of Common Stock)A Award	Director, President and CEO	AAward	+80M sh	—	—	80,000,000
2013-10-11	Astex Pharmaceuticals, IncU Disposition from Tender	Director, Chief Executive Officer	UDisposition from Tender	−13.9K sh	—	—	0
2013-10-11	Astex Pharmaceuticals, IncU Disposition from Tender	Director, Chief Executive Officer	UDisposition from Tender	−70 sh	—	—	0
2013-10-11	Astex Pharmaceuticals, IncEmployee Stock Option (Right to buy)D Disposition to Issuer	Director, Chief Executive Officer	DDisposition to Issuer	−250K sh	—	—	0
2013-10-11	Astex Pharmaceuticals, IncEmployee Stock Option (Right to buy)D Disposition to Issuer	Director, Chief Executive Officer	DDisposition to Issuer	−250K sh	—	—	0
2013-10-11	Astex Pharmaceuticals, IncEmployee Stock Option (Right to buy)D Disposition to Issuer	Director, Chief Executive Officer	DDisposition to Issuer	−200K sh	—	—	0
2013-10-11	Astex Pharmaceuticals, IncEmployee Stock Option (Right to buy)D Disposition to Issuer	Director, Chief Executive Officer	DDisposition to Issuer	−360K sh	—	—	0

Recent filings

Accepted (ET)
Apr 224
MANUSO JAMES S J0000905148-26-001787
SEC(opens sec.gov)
Feb 174
MANUSO JAMES S J0000897069-26-000365
SEC(opens sec.gov)
Jan 54
MANUSO JAMES S J0000905148-26-000036
SEC(opens sec.gov)
May 24
MANUSO JAMES S J0000905148-25-001429
SEC(opens sec.gov)
Jan 64
MANUSO JAMES S J0000897069-25-000035
SEC(opens sec.gov)
Jan 64
MANUSO JAMES S J0000905148-25-000039
SEC(opens sec.gov)
Oct 224
MANUSO JAMES S J0000897069-24-002003
SEC(opens sec.gov)
Jun 134
MANUSO JAMES S J0000905148-24-001712
SEC(opens sec.gov)
Jan 34
MANUSO JAMES S J0001140361-24-000496
SEC(opens sec.gov)
Jun 84
MANUSO JAMES S J0001140361-23-029023
SEC(opens sec.gov)
Apr 214
MANUSO JAMES S J0001140361-23-019677
SEC(opens sec.gov)
Jan 124
MANUSO JAMES S J0001140361-23-001517
SEC(opens sec.gov)
Oct 124
MANUSO JAMES S J0001140361-22-036952
SEC(opens sec.gov)
Jul 64
MANUSO JAMES S J0001140361-22-025284
SEC(opens sec.gov)
Jun 154
MANUSO JAMES S J0001140361-22-023050
SEC(opens sec.gov)

Companies

Address

C/O OPUS GENETICS, INC. 8 DAVIS DRIVE, SUITE 220

DURHAM, NC, 27713