Insider · CIK 0001779990

HENDERSON MICHAEL THOMAS

Reports to the SEC for 4 companies · SAN FRANCISCO, CA

sec.gov

Transactions

Companies

Filings

CIK

0001779990

Forms 4 and 5

Insider transactions

50 trades

Date	Company	Role	Code	Shares	Price	Value	Shares after
2026-09-03	APGEApogee Therapeutics, Inc. · Stock Option (Right to Buy)D Disposition to Issuer	Director, Chief Executive Officer	DDisposition to Issuer	−357K sh	—	—	0
2026-09-03	APGEApogee Therapeutics, Inc.D Disposition to Issuer	Director, Chief Executive Officer	DDisposition to Issuer	−921K sh	—	—	0
2026-09-03	APGEApogee Therapeutics, Inc. · Stock Option (Right to Buy)D Disposition to Issuer	Director, Chief Executive Officer	DDisposition to Issuer	−387K sh	—	—	0
2026-09-03	APGEApogee Therapeutics, Inc. · Stock Option (Right to Buy)D Disposition to Issuer	Director, Chief Executive Officer	DDisposition to Issuer	−253K sh	—	—	0
2026-07-10	APGEApogee Therapeutics, Inc.G Gift	Director, Chief Executive Officer	GGift	−75K sh	—	—	920,941
2026-07-08	APGEApogee Therapeutics, Inc.S Sale	Director, Chief Executive Officer	SSale	−20K sh	$133.63	−$2.67M	995,987
2026-06-22	APGEApogee Therapeutics, Inc.S Sale	Director, Chief Executive Officer	SSale	−80K sh	$132.54	−$10.6M	1,015,987
2026-06-22	SYRESpyre Therapeutics, Inc.S Sale	Director	SSale	−20K sh	$100.00	−$2M	68,606
2026-06-10	APGEApogee Therapeutics, Inc.S Sale	Director, Chief Executive Officer	SSale	−2,305 sh	$86.27	−$199K	1,096,601
2026-06-10	APGEApogee Therapeutics, Inc.S Sale	Director, Chief Executive Officer	SSale	−7,654 sh	$82.78	−$634K	1,101,563
2026-06-10	APGEApogee Therapeutics, Inc.S Sale	Director, Chief Executive Officer	SSale	−1,577 sh	$85.19	−$134K	1,098,906
2026-06-10	APGEApogee Therapeutics, Inc.S Sale	Director, Chief Executive Officer	SSale	−1,080 sh	$84.18	−$90.9K	1,100,483
2026-06-10	APGEApogee Therapeutics, Inc.S Sale	Director, Chief Executive Officer	SSale	−614 sh	$86.89	−$53.4K	1,095,987
2026-06-10	APGEApogee Therapeutics, Inc.S Sale	Director, Chief Executive Officer	SSale	−6,770 sh	$82.21	−$557K	1,109,217
2026-05-27	SYRESpyre Therapeutics, Inc. · Stock Option (Right to Buy)A Award	Director	AAward	+8,026 sh	—	—	8,026
2026-05-13	APGEApogee Therapeutics, Inc.S Sale	Director, Chief Executive Officer	SSale	−18.7K sh	$82.05	−$1.53M	1,117,328
2026-05-13	APGEApogee Therapeutics, Inc.S Sale	Director, Chief Executive Officer	SSale	−1,341 sh	$82.58	−$111K	1,115,987
2026-05-08	SYRESpyre Therapeutics, Inc.S Sale	Director	SSale	−19.3K sh	$75.35	−$1.45M	88,606
2026-05-08	SYRESpyre Therapeutics, Inc.S Sale	Director	SSale	−24.8K sh	$74.76	−$1.86M	107,875
2026-05-08	SYRESpyre Therapeutics, Inc.S Sale	Director	SSale	−33.5K sh	$73.72	−$2.47M	132,689
2026-05-08	SYRESpyre Therapeutics, Inc.S Sale	Director	SSale	−2,404 sh	$72.57	−$174K	166,202
2026-04-16	APGEApogee Therapeutics, Inc. · Stock Option (Right to Buy)M Exercise/Conversion	Director, Chief Executive Officer	MExercise/Conversion	−3,000 sh	—	—	387,012
2026-04-16	APGEApogee Therapeutics, Inc.M Exercise/Conversion	Director, Chief Executive Officer	MExercise/Conversion	+3,000 sh	$22.86	+$68.6K	1,135,987
2026-04-08	APGEApogee Therapeutics, Inc.S Sale	Director, Chief Executive Officer	SSale	−17.8K sh	$82.48	−$1.47M	1,135,187
2026-04-08	APGEApogee Therapeutics, Inc.S Sale	Director, Chief Executive Officer	SSale	−200 sh	$85.00	−$17K	1,132,987
2026-04-08	APGEApogee Therapeutics, Inc.S Sale	Director, Chief Executive Officer	SSale	−2,000 sh	$83.26	−$167K	1,133,187
2026-03-11	APGEApogee Therapeutics, Inc.S Sale	Director, Chief Executive Officer	SSale	−8,363 sh	$74.29	−$621K	1,164,624
2026-03-11	APGEApogee Therapeutics, Inc.S Sale	Director, Chief Executive Officer	SSale	−8,219 sh	$74.83	−$615K	1,156,405
2026-03-11	APGEApogee Therapeutics, Inc.S Sale	Director, Chief Executive Officer	SSale	−3,418 sh	$75.86	−$259K	1,152,987
2026-02-11	APGEApogee Therapeutics, Inc.S Sale	Director, Chief Executive Officer	SSale	−955 sh	$64.99	−$62.1K	1,172,987
2026-02-11	APGEApogee Therapeutics, Inc.S Sale	Director, Chief Executive Officer	SSale	−7,551 sh	$63.73	−$481K	1,173,942
2026-02-11	APGEApogee Therapeutics, Inc.S Sale	Director, Chief Executive Officer	SSale	−11.5K sh	$62.96	−$724K	1,181,493
2026-01-21	SYRESpyre Therapeutics, Inc.J Other	Director	JOther	+63.2K sh	—	—	168,606
2026-01-14	APGEApogee Therapeutics, Inc.S Sale	Director, Chief Executive Officer	SSale	−5,386 sh	$83.16	−$448K	1,193,457
2026-01-14	APGEApogee Therapeutics, Inc.S Sale	Director, Chief Executive Officer	SSale	−470 sh	$83.79	−$39.4K	1,192,987
2026-01-14	APGEApogee Therapeutics, Inc.S Sale	Director, Chief Executive Officer	SSale	−8,476 sh	$79.82	−$677K	1,203,071
2026-01-14	APGEApogee Therapeutics, Inc.S Sale	Director, Chief Executive Officer	SSale	−1,440 sh	$78.64	−$113K	1,211,547
2026-01-14	APGEApogee Therapeutics, Inc.S Sale	Director, Chief Executive Officer	SSale	−2,374 sh	$81.00	−$192K	1,200,697
2026-01-14	APGEApogee Therapeutics, Inc.S Sale	Director, Chief Executive Officer	SSale	−1,854 sh	$82.41	−$153K	1,198,843
2026-01-02	APGEApogee Therapeutics, Inc. · Stock Option (Right to Buy)A Award	Director, Chief Executive Officer	AAward	+253K sh	—	—	253,016
2025-12-10	APGEApogee Therapeutics, Inc.S Sale	Director, Chief Executive Officer	SSale	−10K sh	$75.79	−$758K	1,213,547
2025-12-10	APGEApogee Therapeutics, Inc.S Sale	Director, Chief Executive Officer	SSale	−9,435 sh	$74.88	−$706K	1,223,552
2025-12-10	APGEApogee Therapeutics, Inc.S Sale	Director, Chief Executive Officer	SSale	−560 sh	$76.58	−$42.9K	1,212,987
2025-12-04	APGEApogee Therapeutics, Inc.S Sale	Director, Chief Executive Officer	SSale	−40K sh	$75.01	−$3M	1,232,987
2025-11-13	APGEApogee Therapeutics, Inc.S Sale	Director, Chief Executive Officer	SSale	−1,786 sh	$63.89	−$114K	1,273,087
2025-11-13	APGEApogee Therapeutics, Inc.S Sale	Director, Chief Executive Officer	SSale	−3,340 sh	$61.93	−$207K	1,289,647
2025-11-13	APGEApogee Therapeutics, Inc.S Sale	Director, Chief Executive Officer	SSale	−14.8K sh	$63.14	−$933K	1,274,873
2025-11-13	APGEApogee Therapeutics, Inc.S Sale	Director, Chief Executive Officer	SSale	−100 sh	$64.52	−$6,452	1,272,987
2025-05-29	SYRESpyre Therapeutics, Inc. · Stock Option (Right to Buy)A Award	Director	AAward	+25K sh	—	—	25,000
2025-03-05	APGEApogee Therapeutics, Inc.S Sale	Director, Chief Executive Officer	SSale	−7,326 sh	$29.98	−$220K	1,295,661

Recent filings

Accepted (ET)
Sep 34
HENDERSON MICHAEL THOMAS0001140361-26-035609
SEC(opens sec.gov)
Jul 104
HENDERSON MICHAEL THOMAS0001104659-26-082758
SEC(opens sec.gov)
Jun 244
HENDERSON MICHAEL THOMAS0001104659-26-077426
SEC(opens sec.gov)
Jun 234
HENDERSON MICHAEL THOMAS0001636282-26-000084
SEC(opens sec.gov)
Jun 124
HENDERSON MICHAEL THOMAS0001104659-26-073567
SEC(opens sec.gov)
May 294
HENDERSON MICHAEL THOMAS0001636282-26-000067
SEC(opens sec.gov)
May 154
HENDERSON MICHAEL THOMAS0001104659-26-062867
SEC(opens sec.gov)
May 84
HENDERSON MICHAEL THOMAS0001636282-26-000053
SEC(opens sec.gov)

Companies

Address

C/O APOGEE THERAPEUTICS, INC. 1 LETTERMAN DRIVE, BUILDING B

SAN FRANCISCO, CA, 94129