Insider · CIK 0001985496

Ye Weiguo

Reports to the SEC for 1 company · SAN DIEGO, CA

sec.gov

Transactions

Companies

Filings

CIK

0001985496

Forms 4 and 5

Insider transactions

50 trades

Date	Company	Role	Code	Shares	Price	Value	Shares after
2026-06-18	GYREGYRE THERAPEUTICS, INC.M Exercise/Conversion	Chief Operating Officer	MExercise/Conversion	+3,000 sh	$0.75	+$2,250	703,000
2026-06-18	GYREGYRE THERAPEUTICS, INC.S Sale	Chief Operating Officer	SSale	−3,000 sh	$6.35	−$19.1K	700,000
2026-06-18	GYREGYRE THERAPEUTICS, INC. · Stock Option (Right to Buy)M Exercise/Conversion	Chief Operating Officer	MExercise/Conversion	−3,000 sh	—	—	827,701
2026-06-11	GYREGYRE THERAPEUTICS, INC.M Exercise/Conversion	Chief Operating Officer	MExercise/Conversion	+2,800 sh	$0.75	+$2,100	702,800
2026-06-11	GYREGYRE THERAPEUTICS, INC.S Sale	Chief Operating Officer	SSale	−2,800 sh	$6.17	−$17.3K	700,000
2026-06-11	GYREGYRE THERAPEUTICS, INC. · Stock Option (Right to Buy)M Exercise/Conversion	Chief Operating Officer	MExercise/Conversion	−2,800 sh	—	—	838,701
2026-06-10	GYREGYRE THERAPEUTICS, INC.M Exercise/Conversion	Chief Operating Officer	MExercise/Conversion	+6,418 sh	$0.75	+$4,813.5	706,418
2026-06-10	GYREGYRE THERAPEUTICS, INC.S Sale	Chief Operating Officer	SSale	−6,418 sh	$6.21	−$39.9K	700,000
2026-06-10	GYREGYRE THERAPEUTICS, INC. · Stock Option (Right to Buy)M Exercise/Conversion	Chief Operating Officer	MExercise/Conversion	−6,418 sh	—	—	841,501
2026-06-10	GYREGYRE THERAPEUTICS, INC.M Exercise/Conversion	Chief Operating Officer	MExercise/Conversion	+5,000 sh	$0.75	+$3,750	705,000
2026-06-10	GYREGYRE THERAPEUTICS, INC.S Sale	Chief Operating Officer	SSale	−5,000 sh	$6.24	−$31.2K	700,000
2026-06-10	GYREGYRE THERAPEUTICS, INC. · Stock Option (Right to Buy)M Exercise/Conversion	Chief Operating Officer	MExercise/Conversion	−5,000 sh	—	—	830,701
2026-06-09	GYREGYRE THERAPEUTICS, INC.M Exercise/Conversion	Chief Operating Officer	MExercise/Conversion	+14.5K sh	$0.75	+$10.9K	714,500
2026-06-09	GYREGYRE THERAPEUTICS, INC.S Sale	Chief Operating Officer	SSale	−14.5K sh	$6.14	−$89K	700,000
2026-06-09	GYREGYRE THERAPEUTICS, INC. · Stock Option (Right to Buy)M Exercise/Conversion	Chief Operating Officer	MExercise/Conversion	−14.5K sh	—	—	847,919
2026-06-09	GYREGYRE THERAPEUTICS, INC.M Exercise/Conversion	Chief Operating Officer	MExercise/Conversion	+3,000 sh	$0.75	+$2,250	703,000
2026-06-09	GYREGYRE THERAPEUTICS, INC.S Sale	Chief Operating Officer	SSale	−3,000 sh	$6.15	−$18.5K	700,000
2026-06-09	GYREGYRE THERAPEUTICS, INC. · Stock Option (Right to Buy)M Exercise/Conversion	Chief Operating Officer	MExercise/Conversion	−3,000 sh	—	—	835,701
2026-06-05	GYREGYRE THERAPEUTICS, INC.M Exercise/Conversion	Chief Operating Officer	MExercise/Conversion	+15.4K sh	$0.75	+$11.6K	715,401
2026-06-05	GYREGYRE THERAPEUTICS, INC.S Sale	Chief Operating Officer	SSale	−15.4K sh	$6.40	−$98.6K	700,000
2026-06-05	GYREGYRE THERAPEUTICS, INC. · Stock Option (Right to Buy)M Exercise/Conversion	Chief Operating Officer	MExercise/Conversion	−15.4K sh	—	—	862,419
2026-06-04	GYREGYRE THERAPEUTICS, INC.M Exercise/Conversion	Chief Operating Officer	MExercise/Conversion	+19.6K sh	$0.75	+$14.7K	719,575
2026-06-04	GYREGYRE THERAPEUTICS, INC.S Sale	Chief Operating Officer	SSale	−19.6K sh	$6.13	−$120K	700,000
2026-06-04	GYREGYRE THERAPEUTICS, INC. · Stock Option (Right to Buy)M Exercise/Conversion	Chief Operating Officer	MExercise/Conversion	−19.6K sh	—	—	877,820
2026-05-26	GYREGYRE THERAPEUTICS, INC.M Exercise/Conversion	Chief Operating Officer	MExercise/Conversion	+4,000 sh	$0.75	+$3,000	704,000
2026-05-26	GYREGYRE THERAPEUTICS, INC.S Sale	Chief Operating Officer	SSale	−4,000 sh	$6.10	−$24.4K	700,000
2026-05-26	GYREGYRE THERAPEUTICS, INC. · Stock Option (Right to Buy)M Exercise/Conversion	Chief Operating Officer	MExercise/Conversion	−4,000 sh	—	—	897,395
2026-05-22	GYREGYRE THERAPEUTICS, INC.M Exercise/Conversion	Chief Operating Officer	MExercise/Conversion	+3,500 sh	$0.75	+$2,625	703,500
2026-05-22	GYREGYRE THERAPEUTICS, INC.S Sale	Chief Operating Officer	SSale	−3,500 sh	$6.08	−$21.3K	700,000
2026-05-22	GYREGYRE THERAPEUTICS, INC. · Stock Option (Right to Buy)M Exercise/Conversion	Chief Operating Officer	MExercise/Conversion	−3,500 sh	—	—	901,395
2026-05-21	GYREGYRE THERAPEUTICS, INC.M Exercise/Conversion	Chief Operating Officer	MExercise/Conversion	+12.8K sh	$0.75	+$9,615	712,820
2026-05-21	GYREGYRE THERAPEUTICS, INC.S Sale	Chief Operating Officer	SSale	−12.8K sh	$6.15	−$78.8K	700,000
2026-05-21	GYREGYRE THERAPEUTICS, INC. · Stock Option (Right to Buy)M Exercise/Conversion	Chief Operating Officer	MExercise/Conversion	−12.8K sh	—	—	904,895
2026-05-20	GYREGYRE THERAPEUTICS, INC.M Exercise/Conversion	Chief Operating Officer	MExercise/Conversion	+9,400 sh	$0.75	+$7,050	709,400
2026-05-20	GYREGYRE THERAPEUTICS, INC.S Sale	Chief Operating Officer	SSale	−9,400 sh	$6.15	−$57.8K	700,000
2026-05-20	GYREGYRE THERAPEUTICS, INC. · Stock Option (Right to Buy)M Exercise/Conversion	Chief Operating Officer	MExercise/Conversion	−9,400 sh	—	—	917,715
2026-05-19	GYREGYRE THERAPEUTICS, INC.M Exercise/Conversion	Chief Operating Officer	MExercise/Conversion	+9,120 sh	$0.75	+$6,840	709,120
2026-05-19	GYREGYRE THERAPEUTICS, INC.S Sale	Chief Operating Officer	SSale	−9,120 sh	$6.37	−$58.1K	700,000
2026-05-19	GYREGYRE THERAPEUTICS, INC. · Stock Option (Right to Buy)M Exercise/Conversion	Chief Operating Officer	MExercise/Conversion	−9,120 sh	—	—	927,115
2026-05-18	GYREGYRE THERAPEUTICS, INC.M Exercise/Conversion	Chief Operating Officer	MExercise/Conversion	+200 sh	$0.75	+$150	700,200
2026-05-18	GYREGYRE THERAPEUTICS, INC.S Sale	Chief Operating Officer	SSale	−200 sh	$6.62	−$1,324	700,000
2026-05-18	GYREGYRE THERAPEUTICS, INC. · Stock Option (Right to Buy)M Exercise/Conversion	Chief Operating Officer	MExercise/Conversion	−200 sh	—	—	936,235
2026-05-15	GYREGYRE THERAPEUTICS, INC.M Exercise/Conversion	Chief Operating Officer	MExercise/Conversion	+13.1K sh	$0.75	+$9,825	713,100
2026-05-15	GYREGYRE THERAPEUTICS, INC.S Sale	Chief Operating Officer	SSale	−13.1K sh	$6.65	−$87.1K	700,000
2026-05-15	GYREGYRE THERAPEUTICS, INC. · Stock Option (Right to Buy)M Exercise/Conversion	Chief Operating Officer	MExercise/Conversion	−13.1K sh	—	—	936,435
2026-05-14	GYREGYRE THERAPEUTICS, INC.M Exercise/Conversion	Chief Operating Officer	MExercise/Conversion	+15.6K sh	$0.75	+$11.7K	715,580
2026-05-14	GYREGYRE THERAPEUTICS, INC.S Sale	Chief Operating Officer	SSale	−15.6K sh	$6.91	−$108K	700,000
2026-05-14	GYREGYRE THERAPEUTICS, INC. · Stock Option (Right to Buy)M Exercise/Conversion	Chief Operating Officer	MExercise/Conversion	−15.6K sh	—	—	949,535
2025-04-01	GYREGYRE THERAPEUTICS, INC.M Exercise/Conversion	Chief Operating Officer	MExercise/Conversion	+50K sh	$0.75	+$37.5K	700,000
2025-04-01	GYREGYRE THERAPEUTICS, INC. · Stock Option (Right to Buy)M Exercise/Conversion	Chief Operating Officer	MExercise/Conversion	−50K sh	—	—	965,115

Recent filings

Accepted (ET)
Jun 224
Ye Weiguo0001140361-26-025950
SEC(opens sec.gov)
Jun 154
Ye Weiguo0001140361-26-025208
SEC(opens sec.gov)
Jun 114
Ye Weiguo0001140361-26-024929
SEC(opens sec.gov)
Jun 84
Ye Weiguo0001140361-26-024449
SEC(opens sec.gov)

Companies

GYRE THERAPEUTICS, INC.Chief Operating OfficerGYRE

Address

C/O GYRE THERAPEUTICS, INC. 12730 HIGH BLUFF DRIVE, SUITE 250

SAN DIEGO, CA, 92130