Stock-Based Compensation - Schedule of Fair Value of Each Option Estimated on Date of Grant Using Weighted Average Assumptions (Details) - Stock Options	6 Months Ended
	Jun. 30, 2025	Jun. 30, 2024
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Expected volatility	86.49%	84.99%
Risk-free interest rate	4.30%	4.20%
Expected life (in years)	6 years 10 days	6 years 18 days

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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+ Details

Prelude Therapeutics Inc 10-Q