UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549

FORM 8-K

Current Report
Pursuant to Section 13 or 15(d) of the
Securities Exchange Act of 1934

Date of Report (date of earliest event reported): May 10, 2010

MEDICAL STAFFING NETWORK HOLDINGS, INC.
(Exact name of registrant as specified in its charter)

Delaware		001-31299		65-0865171
(State or other jurisdiction of incorporation)		(Commission File Number)		(IRS Employer Identification No.)

	901 Yamato Road, Suite 110, Boca Raton, FL 33431
	(Address of principal executive offices)

Registrant’s telephone number, including area code: 561-322-1300

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

⃞ Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

⃞ Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

⃞ Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

⃞ Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Item 2.02. Results of Operation and Financial Condition.

On May 10, 2010, the Company issued a press release announcing its results of operations for the first quarter ended March 28, 2010. A copy of the press release is attached as Exhibit 99.1 to this Current Report on Form 8-K.

Item 9.01. Financial Statements and Exhibits.

(a) Exhibits:

	Exhibit	Description

	99.1	Press Release of Medical Staffing Network Holdings, Inc., dated May 10 2010.

SIGNATURE

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

Date:	May 10, 2010	MEDICAL STAFFING NETWORK
		HOLDINGS, INC.


		By:	/s/ Kevin S. Little
			Kevin S. Little
			President and Chief Financial Officer

EXHIBIT INDEX

Exhibit No.	Description

99.1	Press Release of Medical Staffing Network Holdings, Inc., dated May 10 2010.

MEDICAL STAFFING NETWORK HOLDINGS INC 8-K