Note 3 - Summary of Significant Accounting Policies (Details Textual)					3 Months Ended		9 Months Ended								12 Months Ended	21 Months Ended
	Oct. 01, 2025 USD ($) shares	Sep. 15, 2025 USD ($)	Apr. 04, 2025 USD ($)	Jan. 09, 2024 USD ($)	Sep. 30, 2025 USD ($) $ / shares	Sep. 30, 2024 USD ($)	Sep. 30, 2025 USD ($) $ / shares	Sep. 30, 2025 USD ($) $ / shares	Sep. 30, 2025 USD ($) $ / shares	Sep. 30, 2025 USD ($) $ / shares shares	Sep. 30, 2025 USD ($) $ / shares	Sep. 30, 2025 USD ($) TradingDays $ / shares	Sep. 30, 2025 USD ($) Segment $ / shares	Sep. 30, 2024 USD ($)	Dec. 31, 2024 USD ($) $ / shares shares	Sep. 30, 2025 USD ($) $ / shares	Jul. 18, 2024 USD ($) $ / shares
Significant Accounting Policy [Line Item]
Inventory Write-down					$ 1,200,000	$ 600,000		$ 2,600,000						$ 1,600,000
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Goodwill and Intangible Assets					1,200,000,000		$ 1,200,000,000	1,200,000,000	$ 1,200,000,000	$ 1,200,000,000	$ 1,200,000,000	$ 1,200,000,000	$ 1,200,000,000		$ 1,300,000,000	$ 1,200,000,000
Goodwill					484,032,000		484,032,000	484,032,000	484,032,000	484,032,000	484,032,000	484,032,000	484,032,000		529,252,000	484,032,000
Indefinite-Lived Intangible Assets (Excluding Goodwill)					730,400,000		730,400,000	730,400,000	730,400,000	730,400,000	$ 730,400,000	730,400,000	730,400,000		811,600,000	730,400,000
Amount Recognized in Income Due to Inflationary Accounting								10,100,000							10,100,000
Amortization of Intangible Assets					19,531,000	20,433,000		58,835,000						62,290,000
Depreciation					3,200,000	3,700,000		10,400,000						11,900,000
Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate, Percent											21.00%
Unrecognized Tax Benefits, Income Tax Penalties and Interest Accrued					9,900,000		$ 9,900,000	9,900,000	9,900,000	9,900,000	$ 9,900,000	9,900,000	9,900,000			9,900,000
Open Tax Year							2014
Accounts Receivable, Allowance for Credit Loss, Current					1,773,000		$ 1,773,000	1,773,000	$ 1,773,000	$ 1,773,000	$ 1,773,000	$ 1,773,000	$ 1,773,000		$ 1,267,000	$ 1,773,000
Accounts Receivable, Credit Loss Expense (Reversal)					$ 196,400	75,200		$ 530,000						67,500
Common Stock Par Value \| $ / shares					$ 0.01		$ 0.01	$ 0.01	$ 0.01	$ 0.01	$ 0.01	$ 0.01	$ 0.01		$ 0.01	$ 0.01
Stock Repurchased During Period, Value				$ 50,000,000	$ 15,278,000	23,759,000		$ 33,533,000						73,759,000
Share-Based Payment Arrangement, Noncash Expense					3,000,000	2,800,000		7,797,000						7,983,000
Number of Reportable Segments												2	2
Gain (Loss), Foreign Currency Transaction, before Tax					1,100,000	$ 4,100,000		(1,500,000)						$ 100,000
Subsequent Event [Member]
Significant Accounting Policy [Line Item]
Shares retired \| shares	400,000
Shares retired, Value	$ 600,000
Repurchase of Common Stock [Member]
Significant Accounting Policy [Line Item]
Share Repurchase Program, Authorized, Amount			$ 200,000,000														$ 100,000,000
Increase in Share Repurchase Program Authorized Amount			$ 100,000,000
Common Stock Par Value \| $ / shares																	$ 0.01
Stock Repurchased During Period, Shares (in shares) \| shares										24,327,844					25,825,785
Stock Repurchased During Period, Price Per Share (in dollars per share) \| $ / shares									$ 1.36						$ 1.56
Stock Repurchased During Period, Value								33,500,000							$ 40,200,000	$ 73,800,000
Government Contract, BARDA [Member]
Significant Accounting Policy [Line Item]
Accounts Receivable, after Allowance for Credit Loss					$ 2,200,000		$ 2,200,000	2,200,000	$ 2,200,000	$ 2,200,000	$ 2,200,000	$ 2,200,000	$ 2,200,000		$ 3,600,000	$ 2,200,000
Customer Concentration Risk [Member] \| Accounts Receivable [Member] \| Medicare and Medicaid [Member]
Significant Accounting Policy [Line Item]
Concentration Risk, Percentage											6.10%				4.80%
Customer Concentration Risk [Member] \| Accounts Receivable [Member] \| Individual Patients [Member]
Significant Accounting Policy [Line Item]
Concentration Risk, Percentage											2.00%				1.70%
Israel Tax Authority [Member]
Significant Accounting Policy [Line Item]
Income Tax Examination, Estimate of Possible Loss								$ 246,000,000
Software and Software Development Costs [Member]
Significant Accounting Policy [Line Item]
Property, Plant and Equipment, Useful Life (Year)					3 years		3 years	3 years	3 years	3 years	3 years	3 years	3 years			3 years
Minimum [Member]
Significant Accounting Policy [Line Item]
Finite-Lived Intangible Asset, Useful Life (Year)															3 years
Minimum [Member] \| Machinery and Equipment [Member]
Significant Accounting Policy [Line Item]
Property, Plant and Equipment, Useful Life (Year)					5 years		5 years	5 years	5 years	5 years	5 years	5 years	5 years			5 years
Minimum [Member] \| Furniture and Fixtures [Member]
Significant Accounting Policy [Line Item]
Property, Plant and Equipment, Useful Life (Year)					5 years		5 years	5 years	5 years	5 years	5 years	5 years	5 years			5 years
Minimum [Member] \| Building and Building Improvements [Member]
Significant Accounting Policy [Line Item]
Property, Plant and Equipment, Useful Life (Year)					10 years		10 years	10 years	10 years	10 years	10 years	10 years	10 years			10 years
Minimum [Member] \| Vehicles [Member]
Significant Accounting Policy [Line Item]
Property, Plant and Equipment, Useful Life (Year)					3 years		3 years	3 years	3 years	3 years	3 years	3 years	3 years			3 years
Maximum [Member]
Significant Accounting Policy [Line Item]
Finite-Lived Intangible Asset, Useful Life (Year)															20 years
Maximum [Member] \| Machinery and Equipment [Member]
Significant Accounting Policy [Line Item]
Property, Plant and Equipment, Useful Life (Year)					8 years		8 years	8 years	8 years	8 years	8 years	8 years	8 years			8 years
Maximum [Member] \| Furniture and Fixtures [Member]
Significant Accounting Policy [Line Item]
Property, Plant and Equipment, Useful Life (Year)					12 years		12 years	12 years	12 years	12 years	12 years	12 years	12 years			12 years
Maximum [Member] \| Building and Building Improvements [Member]
Significant Accounting Policy [Line Item]
Property, Plant and Equipment, Useful Life (Year)					40 years		40 years	40 years	40 years	40 years	40 years	40 years	40 years			40 years
Maximum [Member] \| Vehicles [Member]
Significant Accounting Policy [Line Item]
Property, Plant and Equipment, Useful Life (Year)					5 years		5 years	5 years	5 years	5 years	5 years	5 years	5 years			5 years
IRELAND
Significant Accounting Policy [Line Item]
Goodwill					$ 89,500,000		$ 89,500,000	$ 89,500,000	$ 89,500,000	$ 89,500,000	$ 89,500,000	$ 89,500,000	$ 89,500,000		$ 79,400,000	$ 89,500,000
Diagnostics [Member]
Significant Accounting Policy [Line Item]
Goodwill					163,400,000		163,400,000	163,400,000	163,400,000	163,400,000	163,400,000	163,400,000	163,400,000		219,700,000	163,400,000
Oncology Transaction [Member]
Significant Accounting Policy [Line Item]
Disposal Group, Including Discontinued Operation, Goodwill					56,300,000		56,300,000	56,300,000	56,300,000	56,300,000	56,300,000	56,300,000	56,300,000			56,300,000
Disposal Group, Held-for-Sale or Disposed of by Sale, Not Discontinued Operations [Member] \| Oncology Transaction [Member]
Significant Accounting Policy [Line Item]
Reclassification of Intangible Assets		$ 30,500,000
In Process Research and Development [Member]
Significant Accounting Policy [Line Item]
Indefinite-Lived Intangible Assets (Excluding Goodwill)					$ 195,000,000		$ 195,000,000	$ 195,000,000	$ 195,000,000	$ 195,000,000	$ 195,000,000	$ 195,000,000	$ 195,000,000		$ 195,000,000	$ 195,000,000

OPKO HEALTH, INC. 10-Q