v3.25.4

Income Taxes - Schedule of Reconciliation of the Federal Statutory Income Tax Rate and the Company's Effective Income Tax Rate (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2025	Dec. 31, 2024	Dec. 31, 2023
Income Tax Disclosure [Abstract]
Federal statutory income tax rate	(21.00%)	(21.00%)	(21.00%)
Provision for income taxes at U.S. federal statutory rate Amount	$ (86,666)
State income taxes		(7.90%)	(8.60%)
Research and development tax credits, percent	(2.30%)	(7.40%)	(6.90%)
Research and development credits, Amount	$ (9,547)
Orphan drug credits, percent	(6.50%)
Orphan drug credits, Amount	$ (26,678)
Other reconciling items, percent	0.20%
Other reconciling items, Amount	$ 666
Stock-based compensation, percent	4.50%	2.00%	1.60%
Stock-based compensation, Amount	$ 18,718
Non-deductible officers' compensation, percent		0.10%	0.00%
Change in valuation allowance, percent	25.10%	34.20%	34.90%
Changes in valuation allowances, Amount	$ 103,507
Effective tax rate	0.00%	0.00%	0.00%
Total tax provision	$ 0

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Intellia Therapeutics, Inc. 10-K