Pay vs Performance Disclosure - USD ($)

12 Months Ended

Dec. 31, 2025

Dec. 31, 2024

Dec. 31, 2023

Pay-Versus-Performance

As required by Section 953(a) of the Dodd-Frank Wall Street Reform and Consumer Protection Act and Item 402(v) of Regulation S-K, we are providing the following disclosure regarding executive compensation for our NEOs our total shareholder return and our net income. Those rules require amounts included in the “compensation actually paid” columns of the table to be calculated according to a particular formula intended to demonstrate the relationship between executive compensation actually paid to a company’s NEOs and the company’s performance. The formula reflects a number of fair value adjustments to equity awards intended to show the change in value of those awards from one year to another. They do not reflect, however, the precise amounts actually earned by or paid to our executives during the years shown in the table.

The compensation committee approves and administers our executive compensation program to align executive compensation with stockholder interests by linking pay to performance. Our overall compensation program includes a mix of short-term and long-term components through our annual incentive plan and equity awards.


Pay-Versus-Performance
Year(1) (a)	Summary Compensation Table Total for PEO (Faga) (2) (b)		Compensation Actually Paid for PEO (Faga) (3) (c)			Average Summary Compensation Table Total for Non-PEO NEO (2) (d)		Average Compensation Actually Paid for Non-PEO NEOs (3) (e)		Value of Initial Fixed $100 Investment Based on Total Shareholder Return (4) (f)		Net Income (g)
2025	$	6,133,943	$	41,738,418		$	2,186,652	$	12,471,713	$	156	$	(13,232,000	)
2024	$	13,630,292	$	9,160,362		$	3,911,208	$	1,844,033	$	43	$	(145,231,000	)
2023	$	7,461,920	$	(1,737,869	)	$	2,349,651	$	544,250	$	69	$	(163,619,000	)

(1) The Company’s PEOs and NEOs for the applicable fiscal years were as follows:


Year	PEO 1	Non-PEO NEOs
2025	Daniel Faga	Dennis Mulroy, Paul Lizzul
2024	Daniel Faga	Dennis Mulroy, Paul Lizzul
2023	Daniel Faga	Eric Loumeau, Paul Lizzul

(2) The dollar amounts reported in these columns represent (i) the amount of total compensation reported in the Summary Compensation Table for the applicable fiscal year our PEO and (ii) the average dollar amounts of total compensation reported in the Summary Compensation Table for the applicable fiscal year for our other NEOs as a group (excluding our PEO).

(3) The dollar amounts reported in these columns represent (i) the “compensation actually paid” to our PEO and (ii) the average “compensation actually paid” to our other NEOs as a group (excluding our PEO), based on their total compensation reported in the Summary Compensation Table for the applicable fiscal years and adjusted in accordance with Item 402(v) of Regulation S-K. The dollar amounts reported in this column for the latest fiscal year are adjusted as shown in the table below:


		2025 (PEO)			2025 (NEO Average)
	Summary Compensation Table - Total Compensation	$	6,133,943		$	2,186,652
-	Grant Date Fair Value of Stock Awards and Option Awards Granted in Fiscal Year	$	(4,937,654	)	$	(1,402,155	)
+	Fair Value at Fiscal Year End of Outstanding and Unvested Stock Awards and Option Awards Granted in Fiscal Year	$	20,014,968		$	5,684,280
+	Change in Fair Value of Outstanding and Unvested Stock Awards and Option Awards Granted in Prior Fiscal Years	$	17,158,745		$	4,805,546
+	Fair Value at Vesting of Stock Awards and Option Awards Granted in Fiscal Year That Vested During Fiscal Year	$	—		$	—
+	Change in Fair Value as of Vesting Date of Stock Awards and Option Awards Granted in Prior Fiscal Years For Which Applicable Vesting Conditions Were Satisfied During Fiscal Year	$	3,368,416		$	1,197,390
-	Fair Value as of Prior Fiscal Year End of Stock Awards and Option Awards Granted in Prior Fiscal Years That Failed to Meet Applicable Vesting Conditions During Fiscal Year	$	—		$	—
=	Compensation Actually Paid	$	41,738,418		$	12,471,713

The fair value or change in fair value, as applicable, of equity awards in the “Compensation Actually Paid” columns has been estimated pursuant to the guidance in ASC Topic 718, and the valuation assumptions used to calculate fair values did not materially differ from those disclosed at the time of the grant.

(4) Pursuant to Item 402(v) of Regulation S-K, the comparison assumes $100 was invested on December 31, 2022 in our common stock. Historic stock price performance is not necessarily indicative of future stock price performance.

Named Executive Officers, Footnote

(1) The Company’s PEOs and NEOs for the applicable fiscal years were as follows:


Year	PEO 1	Non-PEO NEOs
2025	Daniel Faga	Dennis Mulroy, Paul Lizzul
2024	Daniel Faga	Dennis Mulroy, Paul Lizzul
2023	Daniel Faga	Eric Loumeau, Paul Lizzul

PEO Total Compensation Amount

$ 6,133,943

$ 13,630,292

$ 7,461,920

PEO Actually Paid Compensation Amount

$ 41,738,418

9,160,362

(1,737,869)

Adjustment To PEO Compensation, Footnote


		2025 (PEO)			2025 (NEO Average)
	Summary Compensation Table - Total Compensation	$	6,133,943		$	2,186,652
-	Grant Date Fair Value of Stock Awards and Option Awards Granted in Fiscal Year	$	(4,937,654	)	$	(1,402,155	)
+	Fair Value at Fiscal Year End of Outstanding and Unvested Stock Awards and Option Awards Granted in Fiscal Year	$	20,014,968		$	5,684,280
+	Change in Fair Value of Outstanding and Unvested Stock Awards and Option Awards Granted in Prior Fiscal Years	$	17,158,745		$	4,805,546
+	Fair Value at Vesting of Stock Awards and Option Awards Granted in Fiscal Year That Vested During Fiscal Year	$	—		$	—
+	Change in Fair Value as of Vesting Date of Stock Awards and Option Awards Granted in Prior Fiscal Years For Which Applicable Vesting Conditions Were Satisfied During Fiscal Year	$	3,368,416		$	1,197,390
-	Fair Value as of Prior Fiscal Year End of Stock Awards and Option Awards Granted in Prior Fiscal Years That Failed to Meet Applicable Vesting Conditions During Fiscal Year	$	—		$	—
=	Compensation Actually Paid	$	41,738,418		$	12,471,713

Non-PEO NEO Average Total Compensation Amount

$ 2,186,652

3,911,208

2,349,651

Non-PEO NEO Average Compensation Actually Paid Amount

$ 12,471,713

1,844,033

544,250

Adjustment to Non-PEO NEO Compensation Footnote


		2025 (PEO)			2025 (NEO Average)
	Summary Compensation Table - Total Compensation	$	6,133,943		$	2,186,652
-	Grant Date Fair Value of Stock Awards and Option Awards Granted in Fiscal Year	$	(4,937,654	)	$	(1,402,155	)
+	Fair Value at Fiscal Year End of Outstanding and Unvested Stock Awards and Option Awards Granted in Fiscal Year	$	20,014,968		$	5,684,280
+	Change in Fair Value of Outstanding and Unvested Stock Awards and Option Awards Granted in Prior Fiscal Years	$	17,158,745		$	4,805,546
+	Fair Value at Vesting of Stock Awards and Option Awards Granted in Fiscal Year That Vested During Fiscal Year	$	—		$	—
+	Change in Fair Value as of Vesting Date of Stock Awards and Option Awards Granted in Prior Fiscal Years For Which Applicable Vesting Conditions Were Satisfied During Fiscal Year	$	3,368,416		$	1,197,390
-	Fair Value as of Prior Fiscal Year End of Stock Awards and Option Awards Granted in Prior Fiscal Years That Failed to Meet Applicable Vesting Conditions During Fiscal Year	$	—		$	—
=	Compensation Actually Paid	$	41,738,418		$	12,471,713

Compensation Actually Paid vs. Total Shareholder Return

The following graph displays our compensation actually paid (CAP) vs. our cumulative TSR.

1. Cumulative TSR is calculated by dividing the sum of the cumulative amount of dividends for the measurement period, assuming dividend reinvestment, and the difference between the Company’s share price at the end and the beginning of the measurement period by the Company’s share price at the beginning of the measurement period.

Compensation Actually Paid vs. Net Income

The following graph displays our compensation actually paid vs. Net Income. As a pre-commercial biotechnology company, we do not believe Net Income is yet a reasonable metric to measure our financial performance.

1. “Net Income” is calculated by subtracting expenses, interest, and taxes from revenue. The dollar amounts reported represent the amount of Net Income reflected in the Company’s audited financial statements for the applicable year.

Total Shareholder Return Amount

$ 156

Net Income (Loss)

$ (13,232,000)

$ (145,231,000)

$ (163,619,000)

PEO Name

Daniel Faga

Additional 402(v) Disclosure

Pursuant to Item 402(v) of Regulation S-K, the comparison assumes $100 was invested on December 31, 2022 in our common stock. Historic stock price performance is not necessarily indicative of future stock price performance.

PEO | Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table

Pay vs Performance Disclosure

Adjustment to Compensation, Amount

$ (4,937,654)

PEO | Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested

Pay vs Performance Disclosure

Adjustment to Compensation, Amount

20,014,968

PEO | Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested

Pay vs Performance Disclosure

Adjustment to Compensation, Amount

17,158,745

ANAPTYSBIO, INC 10-K/A