Opaleye Management Inc. 4

What Happened

• Opaleye Management Inc., reported as a 10% owner of Alpha Cognition (ACOG), purchased a total of 4,575 shares in open-market/private transactions. The filing shows 2,481 shares on 2026-03-18 at a weighted average price of $5.75 (reported value $14,263) and 2,094 shares on 2026-03-19 at a weighted average price of $5.71 (reported value $11,950). These were purchases (Form 4 code P), which represent accumulation by the reporting entity rather than a sale.

Key Details

• Transaction dates & reported prices: 2026-03-18 — 2,481 shares @ $5.75 (weighted avg; range reported $5.749–$5.75 per footnote F3); 2026-03-19 — 2,094 shares @ $5.71 (weighted avg; range reported $5.699–$5.75 per footnote F4).
• Reported total value: $14,263 (Mar 18) + $11,950 (Mar 19) = $26,213.
• Filing: Form 4 filed 2026-03-20 for reporting period beginning 2026-03-18 (appears filed within the usual 2-business-day reporting window).
• Ownership after transaction: not specified in the provided summary of the filing.
• Important footnotes: F1/F2 indicate securities are owned directly by Opaleye-managed vehicles (Opaleye, L.P. and a separately managed account) and that Opaleye Management Inc. may be deemed to beneficially own those securities as manager; F5 disclaims beneficial ownership except to the extent of pecuniary interest; F3/F4 note the reported prices are weighted averages and that breakdowns by individual trade price are available on request.

Context

• This filing reflects institutional purchasing by a reported 10% owner (investment manager activity), not a corporate officer or director. The purchases indicate accumulation by Opaleye-managed accounts but, per the filing, Opaleye disclaims beneficial ownership beyond its pecuniary interest (see F5). No options, awards, gifts, or sales are involved in these reported transactions.