Opaleye Management Inc. 4

What Happened Opaleye Management Inc., reported as a 10% owner of Alpha Cognition, made open-market purchases of ACOG stock on May 27–29, 2026. The purchases were: 1,161 shares at $5.73 ($6,653) on 5/27; 2,000 shares at a weighted average $5.83 ($11,664) on 5/28; and 70,577 shares at a weighted average $5.90 ($416,397) on 5/29 — a total of 73,738 shares for about $434,714. These were purchases (a bullish-type transaction in the sense of acquiring stock rather than selling).

Key Details

• Transaction dates/prices: 5/27 — 1,161 shares @ $5.73; 5/28 — 2,000 shares @ $5.83 (weighted avg; prices ranged $5.82–$5.85); 5/29 — 70,577 shares @ $5.90 (weighted avg; prices ranged $5.88–$5.90).
• Total value: ~$434,714 for 73,738 shares.
• Shares owned after transaction: not specified in the provided filing details.
• Filing: Form 4 filed 2026-05-29 reporting transactions dated 2026-05-27–05-29 (appears timely based on typical Form 4 rules).
• Footnotes: F1/F2 note the shares are held directly by Opaleye-affiliated funds/accounts (Opaleye may be deemed to beneficially own those securities as manager/portfolio manager). F3/F4 note the reported prices are weighted averages for multiple trades (breakdowns available on request). F5 disclaims beneficial ownership except to the extent of pecuniary interest.

Context Opaleye is an institutional investor (reported as a 10% owner), not an individual executive; such filings reflect institutional buying rather than insider executive trading. The weighted-average footnotes indicate the larger blocks were executed in multiple trades at slightly varying prices; the filer can provide per-trade breakdowns if requested. This Form 4 reports purchases (not sales or option exercises) and therefore signals acquisition activity but does not, by itself, explain the buyer’s motivation.