Opaleye Management Inc. 4

What Happened

• Opaleye Management, Inc. (identified as a 10% owner for Sol‑Gel Technologies Ltd., ticker SLGL) made two open‑market purchases: 300 shares on 2026-07-08 at $73.69 each ($22,107) and 229 shares on 2026-07-10 at $73.95 each ($16,935). Total acquired = 529 shares for approximately $39,042. These were purchases (net buys), which investors often view as more informative than routine sales, though the filing does not state the manager’s motive.

Key Details

• Transaction dates and prices:
  • 2026-07-08 — 300 shares @ $73.69 = $22,107
  • 2026-07-10 — 229 shares @ $73.95 = $16,935
• Total shares purchased: 529; total value: ~$39,042.
• Footnotes of note:
  • F1/F2: Shares are owned directly by Opaleye, L.P. (the Fund) and a separately managed account; as investment/portfolio manager, Opaleye Management, Inc. may be deemed to beneficially own those securities.
  • F3: The reported price is a weighted average; purchases occurred at prices in the range $73.475–$73.845. The filer will provide per‑trade prices on request to the SEC/issuer/holders.
  • F4: Opaleye Management, Inc. disclaims beneficial ownership except to the extent of its pecuniary interest.
• Shares owned after the transaction are not stated in this filing.
• Filing timeliness: Report covers transactions on Jul 8 and was filed Jul 10, 2026 — appears timely (no late‑filing code indicated).

Context

• This filing reflects institutional purchases by a 10% owner/manager (not an executive of Sol‑Gel). Institutional buys can reflect the manager’s allocation decision but do not by themselves explain intent or future company prospects.