MAETZOLD DEREK J 4

4 · CASTLE BIOSCIENCES INC · Filed Dec 11, 2025

Insider Transaction Report

Form 4

Period: 2025-12-09

CASTLE BIOSCIENCES INCCSTL

MAETZOLD DEREK J

DirectorPres. & Chief Exec. Officer

Transactions

Exercise/Conversion
Common Stock
2025-12-09+33,495→ 71,042 total
Tax Payment
Common Stock
2025-12-09$38.25/sh−13,181$504,173→ 57,861 total
Exercise/Conversion
Common Stock
2025-12-10+15,424→ 73,285 total
Tax Payment
Common Stock
2025-12-10$38.02/sh−6,070$230,781→ 67,215 total
Exercise/Conversion
Restricted Stock Units
2025-12-09−33,495→ 33,496 total
→ Common Stock (33,495 underlying)
Exercise/Conversion
Restricted Stock Units
2025-12-10−15,424→ 0 total
→ Common Stock (15,424 underlying)

Holdings

Common Stock
(indirect: By Trust)
52,923
Common Stock
(indirect: By Trust)
44,986
Common Stock
(indirect: By Trust)
3,618
Common Stock
(indirect: By Trust)
3,615
Common Stock
(indirect: By Trust)
85,959
Common Stock
(indirect: By Trust)
18,718
Common Stock
(indirect: By Trust)
44,323

Footnotes (12)

[F1]Each Restricted Stock Unit ("RSU") represents the right to receive one share of the Issuer's Common Stock.
[F10]Held by DJM Grantor Retained Annuity Trust No. 7 of which the Reporting Person is the trustee and beneficiary.
[F11]On December 9, 2022, the Reporting Person was granted 133,983 RSUs which vest in four equal installments beginning on December 9, 2023.
[F12]On December 10, 2021, the Reporting Person was granted 61,698 RSUs which vest in four equal installments beginning on December 10, 2022.
[F2]Held by The Maetzold Descendants 2020 Trust of which the Reporting Person's spouse is the trustee and the Reporting Person's spouse and their children are beneficiaries.
[F3]Held by Derek Maetzold 2020 Irrevocable Trust of which the Reporting Person is the trustee and his children are beneficiaries.
[F4]Held by The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk of which the Reporting Person is the trustee and his child is the beneficiary.
[F5]Held by The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold of which the Reporting Person is the trustee and his child is the beneficiary.
[F6]Held by The Maetzold 2018 Remainder Trust FBO John Derek Maetzold of which the Reporting Person is the trustee and his child is the beneficiary.
[F7]Held by The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold of which the Reporting Person is the trustee and his child is the beneficiary.
[F8]Held by DJM Grantor Retained Annuity Trust No. 5 of which the Reporting Person is the trustee and beneficiary.
[F9]Held by DJM Grantor Retained Annuity Trust No. 6 of which the Reporting Person is the trustee and the beneficiaries are The Maetzold 2018 Remainder Trust FBO John Derek Maetzold, The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk, The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold and The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold.

Documents

1 file

4
wk-form4_1765496931.xmlPrimary
FORM 4